[Hub]/) : Traits : Whole body fat mass :

chr17:41,555,474-43,332,365

Best TWAS P=2.06e-13 · Best GWAS P=2.67e-13 conditioned to 0.152

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C17orf65 0.07 0.06 enet 15 0.07 4.5e-09 6.7 -5.8 6.1e-09 -0.84 0.18 0.82 FALSE
2 GTEx Adipose Subcutaneous ASB16-AS1 0.12 0.05 enet 16 0.05 3.7e-05 6.7 -5.9 3.6e-09 -0.75 0.07 0.82 FALSE
3 GTEx Adipose Visceral Omentum ASB16-AS1 0.14 0.12 lasso 5 0.10 9.8e-06 6.2 -6.3 3.6e-10 -0.84 0.33 0.63 FALSE
4 GTEx Breast Mammary Tissue (Female) ASB16-AS1 0.08 0.04 lasso 2 0.06 7.9e-03 6.2 -6.3 3.0e-10 -0.85 0.05 0.53 FALSE
5 GTEx Cells Transformed fibroblasts ASB16 0.14 0.14 lasso 3 0.12 2.0e-09 6.7 -6.7 2.0e-11 -0.89 0.11 0.89 FALSE
6 GTEx Cells Transformed fibroblasts FZD2 0.11 0.00 enet 21 0.04 1.0e-03 2.0 5.6 2.1e-08 0.48 0.07 0.42 FALSE
7 GTEx Cells Transformed fibroblasts ASB16-AS1 0.17 0.17 lasso 4 0.16 2.3e-12 6.7 -6.5 7.9e-11 -0.83 0.11 0.89 FALSE
8 GTEx Esophagus Mucosa ASB16 0.10 0.10 lasso 4 0.08 8.2e-06 6.7 -6.7 2.0e-11 -0.89 0.07 0.92 FALSE
9 GTEx Esophagus Mucosa ASB16-AS1 0.11 0.08 enet 16 0.07 3.7e-05 4.9 -5.7 1.2e-08 -0.78 0.17 0.82 FALSE
10 GTEx Heart Left Ventricle RP5-882C2.2 0.14 0.08 lasso 5 0.10 8.1e-06 6.3 -6.6 3.5e-11 -0.83 0.04 0.94 FALSE
11 GTEx Lung ASB16 0.09 0.09 enet 15 0.07 3.4e-06 6.7 -5.9 4.7e-09 -0.81 0.05 0.95 FALSE
12 GTEx Lung ASB16-AS1 0.15 0.12 enet 19 0.12 1.5e-09 6.7 -5.5 3.0e-08 -0.79 0.08 0.92 FALSE
13 GTEx Muscle Skeletal ASB16 0.07 0.06 lasso 3 0.06 2.9e-06 5.3 5.8 5.8e-09 0.80 0.12 0.88 FALSE
14 GTEx Nerve Tibial ASB16 0.12 0.07 lasso 5 0.07 7.5e-06 6.7 -6.6 5.4e-11 -0.87 0.10 0.90 FALSE
15 GTEx Nerve Tibial ASB16-AS1 0.17 0.15 lasso 5 0.16 1.4e-11 6.7 -6.3 3.9e-10 -0.85 0.13 0.87 FALSE
16 GTEx Pituitary ASB16-AS1 0.19 0.17 lasso 4 0.22 3.8e-06 4.0 -5.8 5.5e-09 -0.79 0.12 0.72 FALSE
17 GTEx Skin Sun Exposed Lower leg ASB16 0.11 0.03 enet 9 0.02 4.3e-03 6.4 -5.2 1.7e-07 -0.74 0.16 0.62 FALSE
18 GTEx Skin Sun Exposed Lower leg ASB16-AS1 0.13 0.09 lasso 5 0.07 2.7e-06 6.4 -6.3 2.4e-10 -0.87 0.17 0.83 FALSE
19 GTEx Testis ASB16-AS1 0.35 0.25 lasso 5 0.23 1.0e-10 6.7 -6.8 1.2e-11 -0.90 0.06 0.94 FALSE
20 GTEx Thyroid RP5-882C2.2 0.10 0.07 lasso 3 0.07 2.9e-06 6.7 -6.6 3.8e-11 -0.85 0.02 0.97 FALSE
21 GTEx Thyroid ASB16-AS1 0.14 0.06 lasso 2 0.04 5.4e-04 6.7 -6.7 1.6e-11 -0.89 0.08 0.86 FALSE
22 GTEx Whole Blood ASB16 0.11 0.03 enet 24 0.03 6.3e-04 6.4 -5.3 1.5e-07 -0.63 0.11 0.63 FALSE
23 GTEx Whole Blood ASB16-AS1 0.14 0.05 lasso 6 0.04 3.1e-04 6.7 -6.8 9.9e-12 -0.90 0.10 0.90 FALSE
24 The Cancer Genome Atlas Bladder Urothelial Carcinoma ASB16 0.03 0.01 enet 4 0.02 1.2e-02 6.4 -5.8 5.0e-09 -0.82 0.02 0.53 FALSE
25 The Cancer Genome Atlas Bladder Urothelial Carcinoma C17orf65 0.03 0.00 blup 37 0.01 2.3e-02 6.7 -7.3 2.1e-13 -0.92 0.02 0.86 TRUE
26 The Cancer Genome Atlas Colon Adenocarcinoma ASB16 0.05 0.06 blup 40 0.05 4.6e-04 6.4 -6.7 2.2e-11 -0.90 0.04 0.89 FALSE
27 The Cancer Genome Atlas Colon Adenocarcinoma C17orf65 0.05 0.06 blup 38 0.05 4.2e-04 5.3 -6.8 1.0e-11 -0.90 0.08 0.81 FALSE
28 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ASB16 0.02 0.02 blup 39 0.02 3.8e-03 7.3 -7.2 5.1e-13 -0.90 0.01 0.56 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C17orf65 0.03 0.01 lasso 10 0.02 3.6e-03 6.5 -6.9 5.7e-12 -0.82 0.03 0.85 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ASB16 0.02 0.03 blup 40 0.03 1.3e-04 6.4 -6.9 5.9e-12 -0.89 0.12 0.86 FALSE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C17orf65 0.05 0.05 lasso 2 0.05 2.5e-06 5.3 -5.6 1.8e-08 -0.78 0.12 0.88 FALSE
32 The Cancer Genome Atlas Brain Lower Grade Glioma ASB16 0.03 0.03 lasso 3 0.03 3.2e-04 6.2 -6.3 2.3e-10 -0.85 0.13 0.76 FALSE
33 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf65 0.04 0.04 blup 37 0.03 1.4e-04 6.7 -6.5 1.1e-10 -0.86 0.14 0.84 FALSE
34 The Cancer Genome Atlas Lung Adenocarcinoma ASB16 0.02 0.02 lasso 4 0.01 6.3e-03 6.7 -6.1 1.3e-09 -0.83 0.05 0.54 FALSE
35 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ASB16 0.04 0.04 lasso 4 0.03 1.8e-04 7.3 -7.3 3.6e-13 -0.99 0.01 0.99 FALSE
36 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C17orf65 0.07 0.05 lasso 6 0.05 3.1e-06 6.7 -6.5 5.9e-11 -0.88 0.02 0.97 FALSE
37 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C17orf65 0.04 0.03 blup 39 0.03 2.7e-03 7.3 -6.4 1.2e-10 -0.89 0.01 0.92 FALSE
38 The Cancer Genome Atlas Pancreatic Adenocarcinoma C17orf65 0.09 0.02 blup 38 0.04 8.0e-03 6.7 -6.1 1.2e-09 -0.86 0.01 0.60 FALSE
39 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C17orf65 0.09 0.09 enet 8 0.08 2.9e-04 6.2 -6.8 7.5e-12 -0.91 0.03 0.93 FALSE
40 The Cancer Genome Atlas Skin Cutaneous Melanoma C17orf65 0.15 0.05 blup 37 0.09 1.7e-03 6.7 -6.0 1.7e-09 -0.83 0.02 0.64 FALSE
41 The Cancer Genome Atlas Testicular Germ Cell Tumors C17orf65 0.07 0.02 blup 38 0.04 1.1e-02 6.2 -7.0 3.1e-12 -0.86 0.03 0.18 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma C17orf65 0.03 0.03 lasso 7 0.03 3.8e-04 6.7 -7.1 1.8e-12 -0.94 0.02 0.93 FALSE