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chr17:41,555,474-43,332,365

Best TWAS P=2.06e-13 · Best GWAS P=2.67e-13 conditioned to 0.152

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf65	0.03	0.00	blup	37	0.01	2.3e-02	6.7	-7.3	2.1e-13	-0.92	0.02	0.86	TRUE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ASB16	0.04	0.04	lasso	4	0.03	1.8e-04	7.3	-7.3	3.6e-13	-0.99	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ASB16	0.02	0.02	blup	39	0.02	3.8e-03	7.3	-7.2	5.1e-13	-0.90	0.01	0.56	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf65	0.03	0.03	lasso	7	0.03	3.8e-04	6.7	-7.1	1.8e-12	-0.94	0.02	0.93	FALSE
41	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C17orf65	0.07	0.02	blup	38	0.04	1.1e-02	6.2	-7.0	3.1e-12	-0.86	0.03	0.18	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf65	0.03	0.01	lasso	10	0.02	3.6e-03	6.5	-6.9	5.7e-12	-0.82	0.03	0.85	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ASB16	0.02	0.03	blup	40	0.03	1.3e-04	6.4	-6.9	5.9e-12	-0.89	0.12	0.86	FALSE
39	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C17orf65	0.09	0.09	enet	8	0.08	2.9e-04	6.2	-6.8	7.5e-12	-0.91	0.03	0.93	FALSE
23	GTEx	Whole Blood	ASB16-AS1	0.14	0.05	lasso	6	0.04	3.1e-04	6.7	-6.8	9.9e-12	-0.90	0.10	0.90	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf65	0.05	0.06	blup	38	0.05	4.2e-04	5.3	-6.8	1.0e-11	-0.90	0.08	0.81	FALSE
19	GTEx	Testis	ASB16-AS1	0.35	0.25	lasso	5	0.23	1.0e-10	6.7	-6.8	1.2e-11	-0.90	0.06	0.94	FALSE
21	GTEx	Thyroid	ASB16-AS1	0.14	0.06	lasso	2	0.04	5.4e-04	6.7	-6.7	1.6e-11	-0.89	0.08	0.86	FALSE
5	GTEx	Cells Transformed fibroblasts	ASB16	0.14	0.14	lasso	3	0.12	2.0e-09	6.7	-6.7	2.0e-11	-0.89	0.11	0.89	FALSE
8	GTEx	Esophagus Mucosa	ASB16	0.10	0.10	lasso	4	0.08	8.2e-06	6.7	-6.7	2.0e-11	-0.89	0.07	0.92	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	ASB16	0.05	0.06	blup	40	0.05	4.6e-04	6.4	-6.7	2.2e-11	-0.90	0.04	0.89	FALSE
10	GTEx	Heart Left Ventricle	RP5-882C2.2	0.14	0.08	lasso	5	0.10	8.1e-06	6.3	-6.6	3.5e-11	-0.83	0.04	0.94	FALSE
20	GTEx	Thyroid	RP5-882C2.2	0.10	0.07	lasso	3	0.07	2.9e-06	6.7	-6.6	3.8e-11	-0.85	0.02	0.97	FALSE
14	GTEx	Nerve Tibial	ASB16	0.12	0.07	lasso	5	0.07	7.5e-06	6.7	-6.6	5.4e-11	-0.87	0.10	0.90	FALSE
36	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf65	0.07	0.05	lasso	6	0.05	3.1e-06	6.7	-6.5	5.9e-11	-0.88	0.02	0.97	FALSE
7	GTEx	Cells Transformed fibroblasts	ASB16-AS1	0.17	0.17	lasso	4	0.16	2.3e-12	6.7	-6.5	7.9e-11	-0.83	0.11	0.89	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf65	0.04	0.04	blup	37	0.03	1.4e-04	6.7	-6.5	1.1e-10	-0.86	0.14	0.84	FALSE
37	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C17orf65	0.04	0.03	blup	39	0.03	2.7e-03	7.3	-6.4	1.2e-10	-0.89	0.01	0.92	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	ASB16	0.03	0.03	lasso	3	0.03	3.2e-04	6.2	-6.3	2.3e-10	-0.85	0.13	0.76	FALSE
18	GTEx	Skin Sun Exposed Lower leg	ASB16-AS1	0.13	0.09	lasso	5	0.07	2.7e-06	6.4	-6.3	2.4e-10	-0.87	0.17	0.83	FALSE
4	GTEx	Breast Mammary Tissue (Female)	ASB16-AS1	0.08	0.04	lasso	2	0.06	7.9e-03	6.2	-6.3	3.0e-10	-0.85	0.05	0.53	FALSE
3	GTEx	Adipose Visceral Omentum	ASB16-AS1	0.14	0.12	lasso	5	0.10	9.8e-06	6.2	-6.3	3.6e-10	-0.84	0.33	0.63	FALSE
15	GTEx	Nerve Tibial	ASB16-AS1	0.17	0.15	lasso	5	0.16	1.4e-11	6.7	-6.3	3.9e-10	-0.85	0.13	0.87	FALSE
38	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C17orf65	0.09	0.02	blup	38	0.04	8.0e-03	6.7	-6.1	1.2e-09	-0.86	0.01	0.60	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	ASB16	0.02	0.02	lasso	4	0.01	6.3e-03	6.7	-6.1	1.3e-09	-0.83	0.05	0.54	FALSE
40	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C17orf65	0.15	0.05	blup	37	0.09	1.7e-03	6.7	-6.0	1.7e-09	-0.83	0.02	0.64	FALSE
2	GTEx	Adipose Subcutaneous	ASB16-AS1	0.12	0.05	enet	16	0.05	3.7e-05	6.7	-5.9	3.6e-09	-0.75	0.07	0.82	FALSE
11	GTEx	Lung	ASB16	0.09	0.09	enet	15	0.07	3.4e-06	6.7	-5.9	4.7e-09	-0.81	0.05	0.95	FALSE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ASB16	0.03	0.01	enet	4	0.02	1.2e-02	6.4	-5.8	5.0e-09	-0.82	0.02	0.53	FALSE
16	GTEx	Pituitary	ASB16-AS1	0.19	0.17	lasso	4	0.22	3.8e-06	4.0	-5.8	5.5e-09	-0.79	0.12	0.72	FALSE
13	GTEx	Muscle Skeletal	ASB16	0.07	0.06	lasso	3	0.06	2.9e-06	5.3	5.8	5.8e-09	0.80	0.12	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C17orf65	0.07	0.06	enet	15	0.07	4.5e-09	6.7	-5.8	6.1e-09	-0.84	0.18	0.82	FALSE
9	GTEx	Esophagus Mucosa	ASB16-AS1	0.11	0.08	enet	16	0.07	3.7e-05	4.9	-5.7	1.2e-08	-0.78	0.17	0.82	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C17orf65	0.05	0.05	lasso	2	0.05	2.5e-06	5.3	-5.6	1.8e-08	-0.78	0.12	0.88	FALSE
6	GTEx	Cells Transformed fibroblasts	FZD2	0.11	0.00	enet	21	0.04	1.0e-03	2.0	5.6	2.1e-08	0.48	0.07	0.42	FALSE
12	GTEx	Lung	ASB16-AS1	0.15	0.12	enet	19	0.12	1.5e-09	6.7	-5.5	3.0e-08	-0.79	0.08	0.92	FALSE
22	GTEx	Whole Blood	ASB16	0.11	0.03	enet	24	0.03	6.3e-04	6.4	-5.3	1.5e-07	-0.63	0.11	0.63	FALSE
17	GTEx	Skin Sun Exposed Lower leg	ASB16	0.11	0.03	enet	9	0.02	4.3e-03	6.4	-5.2	1.7e-07	-0.74	0.16	0.62	FALSE