TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr18:57,349,900-58,729,694
Best TWAS P=1.57e-18 · Best GWAS P=3.4e-60 conditioned to 1.38e-43
57.4M
57.6M
57.8M
58M
58.2M
58.4M
58.6M
58.8M
0
10
20
30
40
50
60
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
MC4R
0.1
0.02
blup
455
0.04
6.7e-06
12
-8.8
1.6e-18
-0.59
0.23
0.66
TRUE