TWAS hub - MC4R

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.095	0.031	1.6e-05	0.021	0.042	0.028	0.04	0.021	0.0012	6.7e-06	0.00019	1e-05	0.0011

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1
Leg fat-free mass (left)	29.0	153.4	153.4	-12.4
Leg predicted mass (left)	29.0	153.8	153.8	-12.4
Leg predicted mass (right)	28.7	153.0	153.0	-12.4
Arm fat-free mass (left)	28.4	144.0	144.0	-12.0
Leg fat-free mass (right)	28.3	151.3	151.3	-12.3
Basal metabolic rate	28.2	156.0	156.0	-12.5
Arm fat-free mass (right)	27.6	141.6	141.6	-11.9
Whole body fat-free mass	27.3	156.3	156.3	-12.5
Comparative body size at age 10	27.1	74.9	74.9	-8.7
Whole body water mass	27.0	153.8	153.8	-12.4
Weight	26.9	132.2	132.2	-11.5
Arm predicted mass (left)	26.7	135.7	135.7	-11.7
BMI	25.8	149.5	149.5	-12.2
Arm predicted mass (right)	25.7	131.7	131.7	-11.5
Impedance of leg (right)	24.1	116.7	116.7	10.8
Trunk predicted mass	24.0	136.9	136.9	-11.7
Trunk fat-free mass	23.8	136.9	136.9	-11.7
Impedance of whole body	23.8	121.0	121.0	11.0
Impedance of leg (left)	23.2	112.6	112.6	10.6
Arm fat mass (left)	22.1	90.8	90.8	-9.5
Body mass index (BMI)	21.1	89.8	89.8	-9.5
Arm fat mass (right)	21.1	86.8	86.8	-9.3
Waist circumference	21.0	76.8	76.8	-8.8
Leg fat mass (left)	20.5	80.2	80.2	-9.0
Hip circumference	20.4	87.8	87.8	-9.4
Suffer from ‘nerves’	20.0	31.3	31.3	5.6
Leg fat mass (right)	19.8	76.6	76.6	-8.8
Body Mass Index (BMI) (2010)	19.3	26.5	26.5	-5.2
Whole body fat mass	18.5	77.2	77.2	-8.8
Impedance of arm (left)	17.9	82.8	82.8	9.1
Impedance of arm (right)	17.4	80.9	80.9	9.0
Trunk fat mass	16.2	69.4	69.4	-8.3
Type 2 Diabetes (T2D) (2012)	13.9	16.1	16.1	-4.0
Worry (Nagel 2018)	13.7	28.8	28.8	5.4
Arm fat percentage (right)	11.8	46.4	46.4	-6.8
Arm fat percentage (left)	11.3	44.9	44.9	-6.7
Worrier / anxious feelings	10.8	20.3	20.3	4.5
Neuroticism (Nagel 2018)	10.6	24.9	24.9	5.0
Neuroticism score	8.6	17.9	17.9	4.2
Leg fat percentage (left)	8.1	29.4	29.4	-5.4
Body fat percentage	7.7	30.4	30.4	-5.5
Neuroticism (2016)	7.5	10.8	10.8	3.3
Tense / ‘highly strung’	7.5	12.4	12.4	3.5
Leg fat percentage (right)	7.2	26.2	26.2	-5.1
Trunk fat percentage	7.0	28.0	28.0	-5.3
Neuroticism	6.9	16.6	16.6	4.1
Nervous feelings	6.2	11.5	11.5	3.4
Seen doctor (GP) for nerves, anxiety, tension or depression	5.8	8.9	8.9	3.0
Irritability	5.8	9.9	9.9	3.1
Mineral and other dietary supplements	5.7	7.7	7.7	2.8
Type 2 Diabetes (T2D) (2018)	5.5	10.2	10.2	-3.2
Gout (self-reported)	5.5	7.6	7.6	-2.8
HDL Cholesterol	5.4	9.0	9.0	3.0
Long-standing illness, disability or infirmity	5.4	8.3	8.3	-2.9
Average weekly beer plus cider intake	5.4	7.8	7.8	2.8
Miserableness	5.1	8.8	8.8	3.0
Deep venous thrombosis (DVT) (self-reported)	5.1	6.6	6.6	-2.6
Age started oral contraceptive pill	4.9	6.1	6.1	-2.5
Triglycerides	4.7	7.6	7.6	-2.8
Number of treatments/medications taken	4.5	8.1	8.1	-2.8
Alcohol intake frequency.	4.5	10.4	10.4	-3.2
Schizophrenia (2014)	4.4	9.7	9.7	-3.1
Heel bone mineral density (BMD) T-score, automated (right)	4.4	10.0	10.0	-3.2
Hand grip strength (left)	4.3	11.2	11.2	-3.4
Heel bone mineral density (BMD) T-score, automated (left)	4.1	9.2	9.2	-3.0
Frequency of tenseness / restlessness in last 2 weeks	4.1	6.4	6.4	2.5
Blood clot in the leg (DVT)	3.8	5.0	5.0	-2.2
Alcohol drinker status: Never	3.6	4.3	4.3	-2.1
Depressed Affect (Nagel 2018)	3.4	7.1	7.1	2.7
Standing height	3.4	33.9	33.9	-5.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.4	7.2	7.2	2.7
Schizophrenia (2018)	3.3	6.9	6.9	-2.6
Birth weight	3.3	7.1	7.1	2.7
Medication: Allopurinol	3.3	4.4	4.4	-2.1
Eye problems/disorders: Glaucoma	3.3	3.9	3.9	-2.0
Mouth/teeth dental problems: Dentures	3.2	5.4	5.4	-2.3
Worry too long after embarrassment	3.2	5.3	5.3	2.3
Knee pain experienced in last month	3.2	5.0	5.0	-2.2
LDL Cholesterol	3.1	4.9	4.9	2.2
Medication: Levothyroxine sodium	3.0	5.1	5.1	-2.2
Schizophrenia vs Biploar Disorder	2.9	3.8	3.8	-2.0
Multivitamins +/- minerals	2.9	3.6	3.6	-1.9
Medication: Cholesterol lowering	2.9	4.5	4.5	-2.1
Medication: Co-codamol	2.8	3.3	3.3	-1.8
Heart attack/myocardial infarction (self-reported)	2.8	3.6	3.6	-1.9
Prostate Cancer	2.7	3.9	3.9	2.0
Frequency of depressed mood in last 2 weeks	2.7	3.8	3.8	2.0
Taking other prescription medications	2.7	4.2	4.2	-2.1
Hand grip strength (right)	2.6	7.0	7.0	-2.7
Bipolar Disorder or Schizophrenia	2.5	6.1	6.1	-2.5
Depression (Nagel 2018)	2.5	3.7	3.7	1.9
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.1	5.1	-2.3
Height	2.4	46.0	46.0	-6.8
Diabetes diagnosed by doctor	2.4	3.9	3.9	-2.0
Coronary Artery Disease (CAD)	2.2	2.6	2.6	-1.6
Supplements: Glucosamine	2.2	2.8	2.8	-1.7
Had other major operations	2.2	2.7	2.7	1.6
Heart attack	2.2	2.9	2.9	-1.7
Hair/balding pattern: Pattern 3	2.2	3.3	3.3	-1.8
Maternal smoking around birth	2.1	3.0	3.0	-1.7
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	2.4	-1.5
Smoking status: Current	2.1	3.3	3.3	-1.8
Number of self-reported non-cancer illnesses	2.1	3.6	3.6	-1.9
Guilty feelings	2.1	3.1	3.1	1.8
Alcohol usually taken with meals	2.0	3.2	3.2	-1.8
Birth weight of first child	2.0	3.5	3.5	-1.9
Number of live births	1.9	2.7	2.7	-1.6
Vascular/heart problems diagnosed by doctor	1.9	5.1	5.1	2.3
Length of working week for main job	1.8	2.0	2.0	-1.4
Comparative height size at age 10	1.8	9.9	9.9	-3.1
Smoking Status	1.6	3.8	3.8	-2.0
Cardiovascular Disease	1.6	5.3	5.3	-2.3
Medication: Simvastatin	1.6	2.4	2.4	-1.6
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	2.0	-1.4
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	2.6	1.6
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	1.9	1.4
Vitamin and mineral supplements	1.5	2.0	2.0	1.4
High blood pressure	1.5	4.2	4.2	-2.1
Headache pain in last month	1.5	2.5	2.5	1.6
Glaucoma (self-reported)	1.5	1.7	1.7	-1.3
Overall health rating	1.5	3.2	3.2	-1.8
Commuting to job workplace: Public transport	1.5	1.8	1.8	-1.3
Medication for hormone replacement therapy	1.4	1.5	1.5	1.2
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	1.8	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	1.6	1.3
Tinnitus: Yes, now most or all of the time	1.4	1.6	1.6	-1.3
Current tobacco smoking	1.3	2.1	2.1	-1.4
Qualifications: CSEs or equivalent	1.3	1.7	1.7	1.3
Sitting height	1.3	9.5	9.5	-3.1
Exposure to tobacco smoke at home	1.3	1.4	1.4	1.2
Medication: Blood pressure	1.3	2.3	2.3	-1.5
Hypertension (Self-reported)	1.3	3.6	3.6	-1.9
Heel T-Score	1.2	9.2	9.2	-3.0
Systolic Blood Pressure	1.2	6.0	6.0	2.4
Sensitivity / hurt feelings	1.2	2.1	2.1	1.4
Prospective memory result	1.2	1.4	1.4	-1.2
Medication: Ventolin 100micrograms inhaler	1.2	1.5	1.5	-1.2
Crohns Disease (2012)	1.1	1.7	1.7	-1.3
Relative age voice broke	1.1	1.7	1.7	1.3
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	1.1	-1.1
Mean time to correctly identify matches	1.1	2.1	2.1	1.4
Osteoporosis (self-reported)	1.1	1.4	1.4	1.2
Hearing aid user	1.1	1.3	1.3	1.1
Pain type(s) experienced in last month: Hip pain	1.1	1.4	1.4	-1.2
Supplements: Fish oil (including cod liver oil)	1.1	1.5	1.5	-1.2
Supplements: Calcium	1.1	1.2	1.2	-1.1
Fasting Glucose	1.0	1.2	1.2	-1.1
Relative age of first facial hair	1.0	2.0	2.0	1.4
Mouth/teeth dental problems	1.0	1.6	1.6	1.3
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	1.3	1.2
Asthma (self-reported)	1.0	2.0	2.0	-1.4
Diastolic blood pressure, automated reading	1.0	3.0	3.0	-1.7
Lung FVC	0.9	4.5	4.5	2.1
Diabetes (self-reported)	0.9	1.4	1.4	-1.2
Time employed in main current job	0.9	1.0	1.0	-1.0
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	1.8	-1.3
Major Depression (MDD)	0.8	0.9	0.9	1.0
Blood Platelet Count	0.7	7.8	7.8	2.8
Angina	0.7	1.0	1.0	-1.0
Diabetes (mother)	0.7	0.8	0.8	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	0.9	1.0
Allergy	0.7	1.5	1.5	1.2
Pain all over the body in last month	0.7	0.8	0.8	-0.9
Angina (self-reported)	0.7	1.0	1.0	-1.0
Commuting to job workplace: Car/motor vehicle	0.7	0.8	0.8	0.9
Breast cancer (self-reported)	0.7	0.9	0.9	0.9
Pack years of smoking	0.7	1.0	1.0	-1.0
Crohns Disease (2017)	0.6	1.3	1.3	-1.1
Reaction Time	0.6	1.1	1.1	1.0
Respiratory disease	0.6	1.4	1.4	-1.2
Ever had hysterectomy (womb removed)	0.6	0.7	0.7	-0.8
Medication: Atenolol	0.6	0.8	0.8	-0.9
Hair/balding pattern: Pattern 2	0.6	0.8	0.8	0.9
Qualifications: None of the above	0.6	1.2	1.2	-1.1
Asthma	0.6	1.2	1.2	-1.1
Illnesses of mother	0.6	0.7	0.7	0.8
Wheeze or whistling in the chest in last year	0.6	1.1	1.1	-1.1
Health satisfaction	0.6	0.7	0.7	-0.9
Medication: Aspirin	0.6	0.7	0.7	-0.9
Alcohol drinker status: Previous	0.6	0.7	0.7	-0.9
Alzheimer’s Disease (in mother)	0.5	0.6	0.6	-0.8
HbA1C	0.5	0.5	0.5	-0.7
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	0.6	-0.8
Fluid intelligence score	0.5	1.1	1.1	-1.0
Hair/balding pattern: Pattern 4	0.5	1.2	1.2	-1.1
Chronic bronchitis/emphysema (mother)	0.5	0.5	0.5	-0.7
Exposure to tobacco smoke outside home	0.5	0.7	0.7	0.8
Number of children fathered	0.5	0.5	0.5	-0.7
Family relationship satisfaction	0.5	0.6	0.6	-0.8
Loneliness, isolation	0.5	0.7	0.7	0.9
Friendships satisfaction	0.5	0.6	0.6	-0.8
Medication for cholesterol	0.5	0.7	0.7	0.8
High cholesterol (Self-reported)	0.5	0.8	0.8	-0.9
Risk taking	0.5	0.7	0.7	-0.8
Primary Biliary Cirrhosis	0.4	0.6	0.6	-0.8
Blood Red Count	0.4	3.4	3.4	-1.9
Blood White Count	0.4	2.6	2.6	1.6
High blood pressure (mother)	0.4	0.6	0.6	-0.7
Illnesses of siblings	0.4	0.5	0.5	-0.7
Medication for pain relief, constipation, heartburn	0.4	0.7	0.7	0.9
Medication: Ibuprofen	0.4	0.4	0.4	-0.7
Heart disease (mother)	0.4	0.5	0.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.4	-0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.5	-0.7
Mood swings	0.4	0.7	0.7	0.8
Mother’s age at death	0.4	0.5	0.5	0.7
Fractured/broken bones in last 5 years	0.4	0.5	0.5	0.7
Bipolar Disorder (2018)	0.3	0.4	0.4	-0.6
Irritable Bowel Disease (IBD)	0.3	0.6	0.6	-0.8
Supplements: Zinc	0.3	0.3	0.3	-0.5
Diabetes (father)	0.3	0.4	0.4	-0.6
Pack years adult smoking proportion	0.3	0.4	0.4	-0.7
Fed-up feelings	0.3	0.5	0.5	0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.3	0.6
Chronic bronchitis/emphysema (father)	0.3	0.4	0.4	-0.6
Father’s age at death	0.3	0.4	0.4	-0.7
Happiness	0.3	0.4	0.4	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	0.9	0.9
Pulse wave Arterial Stiffness index	0.3	0.3	0.3	-0.6
Loud music exposure frequency	0.3	0.3	0.3	-0.6
Number of full brothers	0.3	0.3	0.3	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.4	-0.6
Chest pain or discomfort	0.3	0.5	0.5	-0.7
Illnesses of siblings: Diabetes	0.3	0.4	0.4	-0.7
Commuting to job workplace: Cycle	0.3	0.4	0.4	-0.6
Pain experienced in last month	0.3	0.5	0.5	0.7
Alzheimer’s Disease (in father)	0.2	0.2	0.2	0.4
Lupus	0.2	0.3	0.3	0.6
Rheumatoid Arthritis	0.2	0.3	0.3	-0.5
Ulcerative Colitis	0.2	0.3	0.3	-0.5
Allergy or Eczema	0.2	0.6	0.6	-0.8
Lung FEV1/FVC ratio	0.2	1.2	1.2	-1.1
Tanning	0.2	2.3	2.3	1.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.2	0.5
Medication: Metformin	0.2	0.3	0.3	-0.5
Serious illness, injury or assault to yourself	0.2	0.3	0.3	-0.5
Stomach or abdominal pain in last month	0.2	0.2	0.2	-0.4
Past tobacco smoking	0.2	0.3	0.3	0.5
Financial difficulties in last 2 years	0.2	0.3	0.3	0.6
Alcohol intake versus 10 years previously	0.2	0.3	0.3	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.3	0.5
Falls in the last year	0.2	0.3	0.3	0.6
Pulse rate	0.2	0.3	0.3	0.6
Depression (self-reported)	0.2	0.3	0.3	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.3	0.5
Medication: Paracetamol	0.2	0.3	0.3	0.5
Qualifications: College or University degree	0.2	0.6	0.6	-0.8
Supplements: Vitamin C	0.2	0.2	0.2	0.5
Qualifications: nursing, teaching	0.2	0.3	0.3	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.2	-0.4
Osteoarthritis (self-reported)	0.2	0.3	0.3	-0.6
Medication: Aspirin	0.2	0.3	0.3	-0.5
Illnesses of father: None of the above (group 1)	0.2	0.2	0.2	0.5
Financial situation satisfaction	0.2	0.2	0.2	-0.4
Medication: Blood pressure	0.2	0.4	0.4	-0.6
Medication: Atorvastatin	0.2	0.2	0.2	-0.5
Number of operations (self-reported)	0.2	0.3	0.3	0.6
Ever depressed for a whole week	0.2	0.2	0.2	0.4
Unable to work because of sickness or disability	0.2	0.2	0.2	-0.5
Myopia	0.2	0.3	0.3	0.6
Intelligence (Savage-Jansen 2018)	0.1	0.4	0.4	0.7
Alzheimer’s Disease (including proxy)	0.1	0.1	0.1	0.3
Bipolar Disorder (2011)	0.1	0.1	0.1	0.4
Blood Eosinophil Count	0.1	0.7	0.7	-0.8
Hypothyroidism (self reported)	0.1	0.3	0.3	-0.5
Hair Pigment	0.1	2.0	2.0	1.4
Average weekly spirits intake	0.1	0.1	0.1	-0.4
Severe depression (siblings)	0.1	0.1	0.1	-0.4
Forced vital capacity (FVC)	0.1	0.3	0.3	0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	0.4	0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.2	0.4
Medication: Lansoprazole	0.1	0.1	0.1	0.3
Pulse wave reflection index	0.1	0.2	0.2	0.4
Medication: Amlodipine	0.1	0.2	0.2	-0.4
High blood pressure (siblings)	0.1	0.1	0.1	0.4
Forced vital capacity (FVC), Best measure	0.1	0.4	0.4	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.2	0.4
Age at first live birth	0.1	0.2	0.2	0.4
Eye problems/disorders: None of the above	0.1	0.1	0.1	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.4
Age at last live birth	0.1	0.1	0.1	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.1	0.3
Medication: Gliclazide	0.1	0.1	0.1	0.4
Wears glasses or contact lenses	0.1	0.2	0.2	0.4
Ever taken oral contraceptive pill	0.1	0.1	0.1	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.2	0.4
Medication: Paracetamol	0.1	0.1	0.1	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.4
Cholesterol lowering medication	0.1	0.1	0.1	-0.3
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	0.3
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.2
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.0	-0.1
Breast Cancer	0.0	0.0	0.0	0.1
Ovarian Cancer	0.0	0.0	0.0	-0.0
Age at First Birth	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.1	0.1	0.4
Chronotype (morning person)	0.0	0.0	0.0	-0.1
Hearing difficulty/problems: Yes	0.0	0.0	0.0	-0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	0.1
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.3
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	0.1
Townsend deprivation index at recruitment	0.0	0.0	0.0	-0.2
Average weekly fortified wine intake	0.0	0.0	0.0	-0.2
Age when periods started (menarche)	0.0	0.0	0.0	0.0
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.1	-0.2
Number of incorrect matches in round	0.0	0.1	0.1	0.2
Hearing difficulty/problems with background noise	0.0	0.0	0.0	-0.0
Had menopause	0.0	0.0	0.0	0.1
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	0.1
Medication: Ramipril	0.0	0.0	0.0	0.0
Noisy workplace	0.0	0.0	0.0	0.1
Lung cancer (father)	0.0	0.0	0.0	0.1
Breastfed as a baby	0.0	0.0	0.0	-0.1
Peak expiratory flow (PEF)	0.0	0.0	0.0	-0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	0.1
Pulse wave peak to peak time	0.0	0.0	0.0	0.1
Shortness of breath walking on level ground	0.0	0.0	0.0	-0.1
Emphysema/chronic bronchitis	0.0	0.0	0.0	0.2
Neck or shoulder pain in last month	0.0	0.0	0.0	0.2
Migraine (self-reported)	0.0	0.0	0.0	0.1
Medication: Omeprazole	0.0	0.0	0.0	-0.2
Medication: Seretide 50 evohaler	0.0	0.0	0.0	0.1
Pulse rate, automated reading	0.0	0.0	0.0	-0.1
Number of full sisters	0.0	0.0	0.0	-0.1
Had major operations	0.0	0.0	0.0	-0.1
Leg pain on walking	0.0	0.0	0.0	0.1
Illnesses of father: Heart disease	0.0	0.0	0.0	-0.1
Smoking status: Previous	0.0	0.0	0.0	0.2
Average weekly red wine intake	0.0	0.0	0.0	-0.1
Ever had bowel cancer screening	0.0	0.0	0.0	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.2
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.2
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.0	0.1
Back pain experienced in last month	0.0	0.0	0.0	-0.0
Average weekly champagne plus white wine intake	0.0	0.1	0.1	0.3
Medication: Lisinopril	0.0	0.0	0.0	-0.2
Illnesses of father: High blood pressure	0.0	0.0	0.0	0.1
Ever smoked	0.0	0.0	0.0	0.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	0.1
Heart disease (siblings)	0.0	0.0	0.0	0.0

Hub : Genes

MC4R

Models

Trait associations