TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
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chr19:3,309,021-4,821,612
Best TWAS P=4.43e-08 · Best GWAS P=1.83e-10 conditioned to 0.00039
3.4M
3.6M
3.8M
4M
4.2M
4.4M
4.6M
4.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Sigmoid
MAP2K2
0.20
0.11
lasso
3
0.13
3.0e-05
-5.0
-5.5
4.4e-08
0.71
0.02
0.85
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
PIAS4
0.14
0.12
lasso
6
0.11
1.6e-13
-5.2
-5.2
2.1e-07
0.66
0.64
0.36
FALSE