[Hub]/) : Traits : Whole body fat mass :

chr19:17,512,412-19,190,906

Best TWAS P=2.41e-17 · Best GWAS P=1.92e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1683 0.09 0.06 enet 14 0.10 6.6e-12 -3.1 5.3 1.2e-07 0.13 0.87 0.13 FALSE
2 GTEx Colon Transverse KIAA1683 0.15 0.02 lasso 3 0.02 3.3e-02 -3.5 5.8 8.6e-09 0.15 0.32 0.17 FALSE
3 GTEx Nerve Tibial KIAA1683 0.25 0.22 lasso 9 0.28 5.2e-20 6.9 5.2 2.5e-07 0.08 1.00 0.00 FALSE
4 GTEx Pancreas AC007192.6 0.19 0.00 enet 28 0.01 1.3e-01 8.5 -5.5 4.9e-08 -0.29 0.04 0.54 FALSE
5 GTEx Testis PDE4C 0.39 0.44 lasso 2 0.43 5.8e-21 -6.0 -6.0 2.4e-09 -0.39 1.00 0.00 FALSE
6 GTEx Testis AC068499.10 0.38 0.41 lasso 3 0.40 6.8e-19 -6.0 -6.1 1.2e-09 -0.41 1.00 0.00 FALSE
7 GTEx Thyroid KIAA1683 0.11 0.07 enet 14 0.12 2.1e-09 4.5 7.0 1.8e-12 0.23 0.58 0.41 FALSE
8 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 6.9 -6.9 4.1e-12 -0.20 0.04 0.14 FALSE
9 NTR Blood IFI30 0.03 0.02 lasso 6 0.02 8.8e-08 8.0 6.4 2.0e-10 0.31 0.15 0.85 FALSE
10 ROSMAP Brain Pre-frontal Cortex PDE4C 0.18 0.12 enet 17 0.19 3.3e-24 -2.5 -5.4 6.2e-08 -0.22 0.80 0.20 FALSE
11 ROSMAP Brain Pre-frontal Cortex JUND 0.17 0.17 lasso 5 0.20 2.7e-25 6.9 5.9 3.9e-09 0.13 1.00 0.00 TRUE
12 YFS Blood MAST3 0.06 0.04 lasso 5 0.04 4.2e-12 8.5 -8.1 7.4e-16 -0.56 0.04 0.96 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma IL12RB1 0.07 0.02 lasso 3 0.01 6.4e-02 5.1 -5.3 1.2e-07 -0.43 0.14 0.04 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma IL12RB1 0.11 0.03 blup 58 0.03 7.3e-03 5.1 -5.3 1.3e-07 -0.49 0.18 0.15 FALSE
15 The Cancer Genome Atlas Glioblastoma Multiforme JUND 0.17 0.00 blup 57 0.03 5.4e-02 6.9 7.1 1.2e-12 0.25 0.01 0.59 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IL12RB1 0.05 0.03 enet 11 0.05 2.3e-06 -2.7 -5.3 9.8e-08 -0.44 0.48 0.41 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 6.9 6.9 3.9e-12 0.20 0.14 0.13 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAST3 0.04 0.02 blup 65 0.01 7.3e-02 8.5 -6.9 6.9e-12 -0.53 0.01 0.30 FALSE
19 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JUND 0.11 0.03 blup 58 0.04 1.4e-03 -3.9 7.0 3.2e-12 0.22 0.04 0.08 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 6.9 6.8 7.9e-12 0.19 0.19 0.04 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma MAST3 0.02 0.02 lasso 3 0.01 1.5e-02 8.4 -8.5 2.4e-17 -0.95 0.01 0.93 TRUE
22 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IL12RB1 0.07 0.04 blup 58 0.06 4.9e-07 5.1 -6.3 2.8e-10 -0.57 0.88 0.10 FALSE
23 The Cancer Genome Atlas Testicular Germ Cell Tumors CRTC1 0.33 0.08 lasso 5 0.12 3.6e-05 -4.2 -5.9 4.0e-09 0.04 0.04 0.52 TRUE
24 The Cancer Genome Atlas Testicular Germ Cell Tumors IL12RB1 0.10 0.01 enet 10 0.06 2.6e-03 2.0 -7.1 1.4e-12 -0.62 0.02 0.56 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma IL12RB1 0.08 0.04 lasso 3 0.05 8.9e-06 4.1 -5.5 3.0e-08 -0.46 0.41 0.35 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma MAST3 0.04 0.02 lasso 2 0.00 3.4e-01 8.4 -8.4 3.8e-17 -0.95 0.02 0.86 FALSE