Best TWAS P=2.33e-07 · Best GWAS P=5.73e-07 conditioned to 0.39
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | RASIP1 | 0.21 | 0.13 | enet | 19 | 0.17 | 1.1e-13 | 3.8 | -5.2 | 2.3e-07 | -0.14 | 0.07 | 0.84 | TRUE |
| 2 | GTEx | Spleen | PPFIA3 | 0.25 | 0.23 | lasso | 4 | 0.21 | 3.9e-06 | 4.7 | -5.1 | 3.1e-07 | -0.90 | 0.01 | 0.96 | TRUE |