Best TWAS P=5.22e-13 · Best GWAS P=1.91e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 7.0 | -7.2 | 5.2e-13 | -0.99 | 0.00 | 1.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC35F6 | 0.05 | 0.04 | enet | 11 | 0.04 | 8.0e-06 | -5.1 | 5.5 | 4.6e-08 | 0.73 | 0.24 | 0.75 | FALSE |