[Hub]/) : Traits : Whole body fat mass : ← →

chr2:35,883,253-37,567,226

Best TWAS P=4.8e-13 · Best GWAS P=5.24e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FEZ2	0.16	0.24	lasso	2	0.22	1.3e-26	7.2	-7.2	4.8e-13	-1.00	0.00	1.00	TRUE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	FEZ2	0.01	0.01	blup	85	0.01	1.0e-03	6.5	-7.1	1.0e-12	-0.92	0.01	0.96	FALSE
3	GTEx	Artery Tibial	CRIM1	0.10	0.04	lasso	4	0.05	1.4e-04	6.5	-7.0	1.8e-12	-0.87	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEZ2	0.06	0.05	blup	87	0.08	1.4e-08	6.9	-6.9	4.5e-12	-0.93	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	AC007401.1	0.10	0.02	lasso	4	0.02	5.4e-03	6.5	6.9	4.6e-12	0.88	0.03	0.94	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	FEZ2	0.41	0.55	lasso	5	0.58	3.1e-93	6.9	-6.9	5.8e-12	-0.95	0.03	0.97	FALSE
14	GTEx	Whole Blood	AC007401.1	0.06	0.06	lasso	5	0.05	4.6e-05	6.5	6.8	8.9e-12	0.91	0.09	0.89	FALSE
8	GTEx	Brain Cerebellar Hemisphere	RP11-490M8.1	0.37	0.18	lasso	4	0.15	1.2e-04	6.6	6.8	1.5e-11	0.92	0.02	0.94	FALSE
19	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FEZ2	0.06	0.05	lasso	4	0.04	3.3e-03	6.8	-6.7	1.6e-11	-0.94	0.03	0.84	FALSE
12	GTEx	Spleen	FEZ2	0.42	0.16	enet	25	0.17	3.9e-05	5.9	6.7	1.8e-11	0.69	0.03	0.90	FALSE
10	GTEx	Brain Cerebellum	AC007401.1	0.27	0.21	enet	5	0.20	1.5e-06	6.6	6.7	2.5e-11	0.87	0.05	0.92	FALSE
15	NTR	Blood	CRIM1	0.09	0.10	lasso	6	0.11	3.1e-32	6.2	-6.7	2.5e-11	-0.93	0.07	0.93	FALSE
6	GTEx	Brain Cerebellar Hemisphere	FEZ2	0.41	0.30	lasso	6	0.28	8.6e-08	6.5	6.6	3.4e-11	0.91	0.02	0.97	FALSE
5	GTEx	Brain Cerebellar Hemisphere	CRIM1	0.36	0.21	lasso	5	0.16	5.4e-05	6.6	6.6	3.6e-11	0.86	0.04	0.90	FALSE
7	GTEx	Brain Cerebellar Hemisphere	AC007401.1	0.40	0.26	lasso	4	0.22	2.3e-06	6.6	6.6	3.9e-11	0.89	0.04	0.95	FALSE
9	GTEx	Brain Cerebellum	FEZ2	0.44	0.26	lasso	6	0.23	2.6e-07	6.4	6.5	6.7e-11	0.85	0.11	0.88	FALSE
13	GTEx	Whole Blood	FEZ2	0.11	0.09	enet	25	0.10	8.4e-10	6.5	6.3	2.7e-10	0.82	0.08	0.92	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	FEZ2	0.11	0.03	blup	84	0.07	6.1e-05	7.2	-6.2	4.4e-10	-0.91	0.02	0.97	FALSE
11	GTEx	Brain Cerebellum	RP11-490M8.1	0.21	0.21	lasso	4	0.20	1.4e-06	5.9	6.2	5.6e-10	0.84	0.04	0.94	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FEZ2	0.04	0.00	blup	88	0.02	6.1e-03	6.4	-5.9	4.2e-09	-0.84	0.03	0.80	FALSE
4	GTEx	Artery Tibial	RP11-78I14.1	0.10	0.08	enet	16	0.07	4.2e-06	6.5	-5.8	5.6e-09	-0.72	0.08	0.87	FALSE
21	The Cancer Genome Atlas	Esophageal Carcinoma	FEZ2	0.11	0.01	blup	87	0.02	7.1e-02	6.4	-5.8	7.0e-09	-0.82	0.04	0.36	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	FEZ2	0.07	0.06	blup	87	0.06	2.4e-06	6.6	-5.8	7.2e-09	-0.82	0.14	0.85	FALSE
17	YFS	Blood	FEZ2	0.40	0.52	bslmm	615	0.55	7.7e-222	6.2	5.6	2.6e-08	0.83	0.55	0.45	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FEZ2	0.18	0.21	lasso	6	0.21	5.3e-08	-4.2	-5.4	6.4e-08	-0.68	0.13	0.84	FALSE