Best TWAS P=7.37e-09 · Best GWAS P=9.04e-08 conditioned to 0.000966
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PCYT1A | 0.11 | 0.03 | lasso | 3 | 0.00 | 0.3920 | 5.3 | -5.3 | 1.2e-07 | -0.52 | 0.02 | 0.86 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | UBXN7 | 0.20 | 0.00 | enet | 16 | 0.02 | 0.0352 | -4.6 | -5.4 | 8.1e-08 | -0.58 | 0.03 | 0.86 | FALSE |
| 3 | GTEx | Spleen | PCYT1A | 0.19 | 0.05 | lasso | 4 | 0.09 | 0.0031 | -4.1 | -5.2 | 2.2e-07 | -0.53 | 0.05 | 0.51 | FALSE |
| 4 | GTEx | Stomach | SLC51A | 0.13 | 0.06 | enet | 12 | 0.03 | 0.0193 | 4.7 | -5.8 | 7.4e-09 | -0.40 | 0.01 | 0.94 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN7 | 0.02 | 0.01 | blup | 45 | 0.02 | 0.0042 | 4.0 | -5.8 | 9.0e-09 | -0.67 | 0.02 | 0.57 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PCYT1A | 0.12 | 0.05 | blup | 68 | 0.06 | 0.0002 | 4.9 | -5.5 | 4.7e-08 | -0.23 | 0.01 | 0.91 | FALSE |