Best TWAS P=2.59e-08 · Best GWAS P=7.65e-07 conditioned to 0.0811
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SLC26A1 | 0.12 | 0.06 | bslmm | 400 | 0.08 | 8.0e-10 | 4.2 | 5.3 | 9.3e-08 | 0.42 | 0.05 | 0.82 | TRUE |
2 | GTEx | Artery Tibial | GAK | 0.19 | 0.03 | enet | 29 | 0.10 | 2.4e-08 | -2.9 | 5.1 | 2.6e-07 | 0.57 | 0.00 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PCGF3 | 0.03 | 0.00 | blup | 69 | 0.01 | 3.7e-03 | 3.2 | 5.6 | 2.6e-08 | 0.44 | 0.00 | 0.04 | TRUE |