TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr4:2,229,206-3,943,984
Best TWAS P=1.2e-08 · Best GWAS P=2.16e-07 conditioned to 0.0439
2.2M
2.4M
2.6M
2.8M
3M
3.2M
3.4M
3.6M
3.8M
4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Whole Blood
HTT
0.10
0.00
enet
15
0.03
1.4e-03
4.8
5.7
1.2e-08
-0.40
0.06
0.52
TRUE
4
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
RNF4
0.14
0.02
blup
47
0.07
3.1e-04
3.4
5.2
2.3e-07
-0.22
0.00
0.02
TRUE
1
GTEx
Cells Transformed fibroblasts
NOP14
0.12
0.06
enet
11
0.09
2.9e-07
-3.7
5.6
2.1e-08
-0.77
0.07
0.90
FALSE
2
GTEx
Colon Transverse
GRK4
0.27
0.25
enet
18
0.25
2.4e-12
-4.5
5.3
1.1e-07
-0.95
0.02
0.97
FALSE