Best TWAS P=1.2e-08 · Best GWAS P=2.16e-07 conditioned to 0.0439
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NOP14 | 0.12 | 0.06 | enet | 11 | 0.09 | 2.9e-07 | -3.7 | 5.6 | 2.1e-08 | -0.77 | 0.07 | 0.90 | FALSE |
| 2 | GTEx | Colon Transverse | GRK4 | 0.27 | 0.25 | enet | 18 | 0.25 | 2.4e-12 | -4.5 | 5.3 | 1.1e-07 | -0.95 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Whole Blood | HTT | 0.10 | 0.00 | enet | 15 | 0.03 | 1.4e-03 | 4.8 | 5.7 | 1.2e-08 | -0.40 | 0.06 | 0.52 | TRUE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | RNF4 | 0.14 | 0.02 | blup | 47 | 0.07 | 3.1e-04 | 3.4 | 5.2 | 2.3e-07 | -0.22 | 0.00 | 0.02 | TRUE |