[Hub]/) : Traits : Whole body fat mass :

chr6:160,071,844-161,571,560

Best TWAS P=1.95e-09 · Best GWAS P=3.26e-10 conditioned to 0.00139

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia SLC22A3 0.15 0.10 enet 39 0.11 5.6e-04 -5.4 -6.0 2.0e-09 0.64 0.21 0.50 TRUE
2 GTEx Brain Frontal Cortex BA9 SLC22A3 0.26 0.08 lasso 6 0.05 1.5e-02 -4.3 -5.2 2.3e-07 0.62 0.10 0.71 FALSE
3 GTEx Nerve Tibial SLC22A3 0.20 0.10 lasso 7 0.13 3.2e-09 -5.2 -5.3 1.2e-07 0.54 0.84 0.15 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic SLC22A3 0.15 0.05 lasso 9 0.05 9.9e-04 -4.5 -5.8 4.9e-09 0.82 0.02 0.98 FALSE
5 GTEx Skin Sun Exposed Lower leg SLC22A3 0.29 0.14 lasso 10 0.20 3.7e-16 3.3 -5.3 1.3e-07 0.52 0.96 0.04 FALSE
6 ROSMAP Brain Pre-frontal Cortex SLC22A3 0.14 0.20 lasso 10 0.19 2.4e-24 -4.8 -5.1 2.8e-07 0.61 0.94 0.06 FALSE