[Hub]/) : Traits : Whole body fat mass : ← →

chr7:2,032,803-3,581,391

Best TWAS P=1.58e-21 · Best GWAS P=3.13e-19 conditioned to 0.367

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-8.6	9.5	1.6e-21	-0.90	0.06	0.94	TRUE
3	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-9.0	-8.8	1.2e-18	0.99	0.00	1.00	FALSE
12	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-8.5	-8.8	1.9e-18	0.94	0.02	0.92	FALSE
16	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	5.4	-8.3	1.0e-16	0.71	0.01	0.71	FALSE
8	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-8.6	-8.3	1.1e-16	0.94	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	6.2	7.5	6.2e-14	-0.43	1.00	0.00	FALSE
15	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	6.2	-7.0	3.7e-12	0.52	1.00	0.00	FALSE
2	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-8.6	-6.8	8.4e-12	0.84	0.03	0.97	FALSE
7	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-7.8	-6.8	9.8e-12	0.87	0.07	0.93	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	2.7	-6.7	1.7e-11	0.78	0.05	0.76	FALSE
5	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-3.8	-6.6	4.2e-11	0.87	0.02	0.92	FALSE
13	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-5.4	-6.6	4.2e-11	0.63	0.90	0.10	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-4.0	-6.6	4.5e-11	0.86	0.03	0.96	FALSE
4	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-8.6	-6.3	3.8e-10	0.86	0.04	0.96	FALSE
11	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-4.1	-6.1	8.1e-10	0.87	0.16	0.84	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	5.4	6.1	9.2e-10	-0.60	0.04	0.90	FALSE
10	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-4.1	-6.1	1.0e-09	0.86	0.73	0.27	FALSE
9	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-7.7	-6.1	1.1e-09	0.78	0.02	0.98	FALSE