[Hub]/) : Traits : Whole body fat mass :

chr7:2,032,803-3,581,391

Best TWAS P=1.58e-21 · Best GWAS P=3.13e-19 conditioned to 0.367

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 6.2 7.5 6.2e-14 -0.43 1.00 0.00 FALSE
2 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -8.6 -6.8 8.4e-12 0.84 0.03 0.97 FALSE
3 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -9.0 -8.8 1.2e-18 0.99 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -8.6 -6.3 3.8e-10 0.86 0.04 0.96 FALSE
5 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -3.8 -6.6 4.2e-11 0.87 0.02 0.92 FALSE
6 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -4.0 -6.6 4.5e-11 0.86 0.03 0.96 FALSE
7 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -7.8 -6.8 9.8e-12 0.87 0.07 0.93 FALSE
8 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -8.6 -8.3 1.1e-16 0.94 0.02 0.98 FALSE
9 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -7.7 -6.1 1.1e-09 0.78 0.02 0.98 FALSE
10 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -4.1 -6.1 1.0e-09 0.86 0.73 0.27 FALSE
11 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -4.1 -6.1 8.1e-10 0.87 0.16 0.84 FALSE
12 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -8.5 -8.8 1.9e-18 0.94 0.02 0.92 FALSE
13 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -5.4 -6.6 4.2e-11 0.63 0.90 0.10 FALSE
14 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -8.6 9.5 1.6e-21 -0.90 0.06 0.94 TRUE
15 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 6.2 -7.0 3.7e-12 0.52 1.00 0.00 FALSE
16 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 5.4 -8.3 1.0e-16 0.71 0.01 0.71 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 5.4 6.1 9.2e-10 -0.60 0.04 0.90 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 2.7 -6.7 1.7e-11 0.78 0.05 0.76 FALSE