TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr7:4,776,547-7,318,723
Best TWAS P=5.78e-09 · Best GWAS P=7.7e-10 conditioned to 9.42e-08
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
ZDHHC4
0.29
0.09
enet
19
0.13
7.5e-08
4.2
-5.8
5.8e-09
-0.27
0.9
0.05
TRUE
2
GTEx
Esophagus Mucosa
AC092171.4
0.14
0.07
lasso
3
0.05
3.2e-04
5.1
5.2
1.6e-07
-0.10
0.0
0.99
TRUE
3
METSIM
Adipose
FBXL18
0.08
0.06
lasso
3
0.05
1.6e-07
5.1
5.2
1.6e-07
-0.10
0.0
1.00
FALSE