Best TWAS P=3.2e-08 · Best GWAS P=1.17e-06 conditioned to 0.0281
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | FAM85A | 0.09 | 0.04 | enet | 28 | 0.04 | 1.4e-04 | -4.5 | 5.5 | 3.2e-08 | 0.55 | 0.01 | 0.91 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | RP11-481A20.11 | 0.06 | 0.04 | blup | 286 | 0.04 | 2.2e-06 | 3.8 | 5.2 | 1.7e-07 | 0.73 | 0.23 | 0.48 | FALSE |