TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat mass
:
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chr8:11,171,087-12,751,157
Best TWAS P=3.2e-08 · Best GWAS P=1.17e-06 conditioned to 0.0281
11.2M
11.4M
11.6M
11.8M
12M
12.2M
12.4M
12.6M
12.8M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
FAM85A
0.09
0.04
enet
28
0.04
1.4e-04
-4.5
5.5
3.2e-08
0.55
0.01
0.91
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
RP11-481A20.11
0.06
0.04
blup
286
0.04
2.2e-06
3.8
5.2
1.7e-07
0.73
0.23
0.48
FALSE