TWAS
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Genes
Traits
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Traits
:
Whole body fat mass
:
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chr8:8,165,004-10,985,432
Best TWAS P=1.74e-09 · Best GWAS P=4.28e-09 conditioned to 0.0113
8M
8.5M
9M
9.5M
10M
10.5M
11M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
NTR
Blood
MSRA
0.02
0.01
blup
833
0.01
2.3e-05
3.6
-6.0
1.7e-09
-0.66
0.48
0.51
TRUE
1
GTEx
Cells Transformed fibroblasts
ERI1
0.34
0.35
lasso
7
0.35
1.9e-27
4.8
-5.2
1.9e-07
-0.52
0.01
0.98
FALSE