[Hub]/) : Traits : Whole body fat mass : ← →

chr8:21,249,296-24,094,711

Best TWAS P=2.98e-10 · Best GWAS P=5.24e-11 conditioned to 0.577

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Cells Transformed fibroblasts	SLC25A37	0.13	0.05	lasso	5	0.04	3.0e-04	-6.6	6.3	3.0e-10	-0.86	0.00	1.00	TRUE
7	GTEx	Esophagus Mucosa	AC091171.1	0.14	0.07	lasso	4	0.05	2.2e-04	5.4	5.6	2.5e-08	-0.06	0.01	0.98	TRUE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	CHMP7	0.03	0.03	blup	89	0.01	3.8e-02	3.8	-5.3	1.4e-07	0.10	0.02	0.23	TRUE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOXL2	0.16	0.03	lasso	4	0.05	1.2e-03	-4.9	5.9	3.2e-09	-0.59	0.01	0.79	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC25A37	0.11	0.09	lasso	5	0.09	7.8e-10	-5.1	-5.6	2.2e-08	0.59	0.87	0.13	FALSE
20	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NUDT18	0.15	0.17	lasso	4	0.12	2.3e-04	-5.4	-5.5	3.3e-08	0.05	0.01	0.96	FALSE
5	GTEx	Cells Transformed fibroblasts	AC091171.1	0.15	0.06	lasso	2	0.05	2.2e-04	-5.5	5.5	5.0e-08	-0.05	0.01	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	NUDT18	0.10	0.04	enet	6	0.03	4.7e-03	5.0	5.4	7.0e-08	-0.05	0.02	0.89	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	NUDT18	0.11	0.22	lasso	6	0.22	3.6e-24	-5.5	-5.4	7.3e-08	0.06	0.01	0.99	FALSE
6	GTEx	Esophagus Mucosa	FAM160B2	0.15	0.05	enet	19	0.09	1.7e-06	5.3	5.3	1.0e-07	0.01	0.01	0.98	FALSE
9	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	NUDT18	0.09	0.03	blup	45	0.08	1.3e-04	-5.3	-5.3	1.1e-07	0.06	0.02	0.96	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	NUDT18	0.10	0.16	lasso	2	0.16	2.3e-09	-5.3	-5.3	1.1e-07	0.05	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HR	0.06	0.01	bslmm	452	0.03	3.8e-05	-2.6	5.3	1.2e-07	-0.01	0.03	0.90	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM160B2	0.06	0.07	lasso	1	0.06	2.3e-04	5.3	5.3	1.2e-07	-0.05	0.01	0.89	FALSE
8	GTEx	Thyroid	NUDT18	0.17	0.19	lasso	3	0.19	3.2e-14	-5.2	-5.2	1.8e-07	0.05	0.03	0.97	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FAM160B2	0.02	0.02	blup	53	0.02	1.8e-03	-5.5	5.2	2.2e-07	-0.05	0.02	0.92	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NUDT18	0.06	0.08	lasso	3	0.07	1.6e-08	-5.3	-5.2	2.2e-07	0.05	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	FAM160B2	0.08	0.06	lasso	4	0.05	1.4e-05	-5.5	5.2	2.2e-07	-0.05	0.01	0.99	FALSE
3	GTEx	Cells Transformed fibroblasts	FAM160B2	0.18	0.09	lasso	5	0.10	4.0e-08	-5.5	5.1	3.0e-07	-0.06	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Rectum Adenocarcinoma	NUDT18	0.24	0.08	lasso	6	0.06	1.7e-02	-5.4	-5.1	3.0e-07	0.05	0.01	0.69	FALSE