[Hub]/) : Traits : Whole body fat mass :

chr8:21,249,296-24,094,711

Best TWAS P=2.98e-10 · Best GWAS P=5.24e-11 conditioned to 0.577

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HR 0.06 0.01 bslmm 452 0.03 3.8e-05 -2.6 5.3 1.2e-07 -0.01 0.03 0.90 FALSE
2 GTEx Cells Transformed fibroblasts SLC25A37 0.13 0.05 lasso 5 0.04 3.0e-04 -6.6 6.3 3.0e-10 -0.86 0.00 1.00 TRUE
3 GTEx Cells Transformed fibroblasts FAM160B2 0.18 0.09 lasso 5 0.10 4.0e-08 -5.5 5.1 3.0e-07 -0.06 0.01 0.99 FALSE
4 GTEx Cells Transformed fibroblasts NUDT18 0.10 0.04 enet 6 0.03 4.7e-03 5.0 5.4 7.0e-08 -0.05 0.02 0.89 FALSE
5 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.5 5.5 5.0e-08 -0.05 0.01 0.98 FALSE
6 GTEx Esophagus Mucosa FAM160B2 0.15 0.05 enet 19 0.09 1.7e-06 5.3 5.3 1.0e-07 0.01 0.01 0.98 FALSE
7 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.4 5.6 2.5e-08 -0.06 0.01 0.98 TRUE
8 GTEx Thyroid NUDT18 0.17 0.19 lasso 3 0.19 3.2e-14 -5.2 -5.2 1.8e-07 0.05 0.03 0.97 FALSE
9 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.3 -5.3 1.1e-07 0.06 0.02 0.96 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma FAM160B2 0.06 0.07 lasso 1 0.06 2.3e-04 5.3 5.3 1.2e-07 -0.05 0.01 0.89 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC25A37 0.11 0.09 lasso 5 0.09 7.8e-10 -5.1 -5.6 2.2e-08 0.59 0.87 0.13 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOXL2 0.16 0.03 lasso 4 0.05 1.2e-03 -4.9 5.9 3.2e-09 -0.59 0.01 0.79 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NUDT18 0.10 0.16 lasso 2 0.16 2.3e-09 -5.3 -5.3 1.1e-07 0.05 0.02 0.98 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.5 -5.4 7.3e-08 0.06 0.01 0.99 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FAM160B2 0.02 0.02 blup 53 0.02 1.8e-03 -5.5 5.2 2.2e-07 -0.05 0.02 0.92 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NUDT18 0.06 0.08 lasso 3 0.07 1.6e-08 -5.3 -5.2 2.2e-07 0.05 0.02 0.98 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma CHMP7 0.03 0.03 blup 89 0.01 3.8e-02 3.8 -5.3 1.4e-07 0.10 0.02 0.23 TRUE
18 The Cancer Genome Atlas Rectum Adenocarcinoma NUDT18 0.24 0.08 lasso 6 0.06 1.7e-02 -5.4 -5.1 3.0e-07 0.05 0.01 0.69 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma FAM160B2 0.08 0.06 lasso 4 0.05 1.4e-05 -5.5 5.2 2.2e-07 -0.05 0.01 0.99 FALSE
20 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.4 -5.5 3.3e-08 0.05 0.01 0.96 FALSE