TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
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→
chr10:101,975,269-103,493,226
Best TWAS P=1.44e-08 · Best GWAS P=1.7e-09 conditioned to 0.322
102M
102.2M
102.4M
102.6M
102.8M
103M
103.2M
103.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellum
RP11-179B2.2
0.37
0.21
lasso
4
0.20
1.4e-06
4.9
5.7
1.4e-08
0.70
0.27
0.41
TRUE
2
METSIM
Adipose
SFXN3
0.12
0.00
blup
415
0.04
1.6e-06
1.9
5.4
8.4e-08
0.26
0.16
0.03
TRUE