[Hub]/) : Traits : Whole body fat mass :

chr10:103,746,504-105,282,664

Best TWAS P=5.31e-08 · Best GWAS P=3.49e-07 conditioned to 0.0144

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ARL3 0.20 0.09 enet 32 0.07 3.7e-03 5.1 5.4 5.3e-08 0.57 0.05 0.87 TRUE
2 GTEx Breast Mammary Tissue (Female) CYP17A1-AS1 0.14 0.01 lasso 11 0.00 4.7e-01 4.1 5.1 3.0e-07 0.60 0.04 0.37 FALSE
3 GTEx Nerve Tibial CYP17A1-AS1 0.14 0.08 lasso 6 0.06 7.2e-05 4.9 5.2 2.0e-07 0.82 0.02 0.97 FALSE
4 ROSMAP Brain Pre-frontal Cortex CYP17A1-AS1 0.15 0.18 lasso 6 0.19 1.3e-23 5.1 5.3 1.4e-07 0.81 0.02 0.98 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma AS3MT 0.06 0.09 enet 6 0.07 1.3e-06 4.7 -5.3 9.6e-08 -0.80 0.04 0.95 FALSE