Hub : Genes

SFXN3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1610	0.0450	2.0e-05	0.039	0.045	0.065	0.103	0.068	1.6e-05	3.5e-06	2.1e-08	1.5e-12	1.2e-08
2	GTEx	Brain Cortex	0.3150	0.1010	4.6e-03	0.029	NA	0.126	NA	0.086	5.3e-02	NA	2.5e-04	NA	2.2e-03
3	GTEx	Nerve Tibial	0.2361	0.0691	4.1e-04	0.066	NA	0.143	NA	0.168	2.0e-05	NA	2.6e-10	NA	5.7e-12
4	GTEx	Skin Sun Exposed Lower leg	0.1740	0.0610	1.4e-03	0.005	NA	0.005	NA	0.007	1.1e-01	NA	1.2e-01	NA	7.7e-02
5	METSIM	Adipose	0.1176	0.0335	8.2e-06	0.002	0.039	0.023	NA	0.012	1.2e-01	1.6e-06	1.7e-04	NA	6.0e-03
6	NTR	Blood	0.0289	0.0111	1.1e-03	0.023	0.007	0.021	0.014	0.024	4.2e-08	1.7e-03	1.8e-07	1.6e-05	2.7e-08
7	ROSMAP	Brain Pre-frontal Cortex	0.0959	0.0373	2.9e-03	0.000	0.019	0.042	0.042	0.006	3.3e-01	1.3e-03	3.2e-06	4.0e-06	5.1e-02
8	TCGA	Cervical Squamous Cell Carcinoma	0.1050	0.0510	6.2e-03	0.037	0.047	0.012	NA	0.013	6.6e-03	2.2e-03	8.2e-02	NA	7.0e-02
9	TCGA	Colon Adenocarcinoma	0.0700	0.0360	9.2e-03	0.033	0.038	0.053	NA	0.062	5.2e-03	2.9e-03	5.4e-04	NA	1.8e-04
10	TCGA	Brain Lower Grade Glioma	0.1786	0.0695	5.0e-03	0.049	0.042	0.049	NA	0.046	2.6e-06	1.4e-05	2.8e-06	NA	5.4e-06
11	TCGA	Lung Squamous Cell Carcinoma	0.0749	0.0323	1.6e-03	0.040	0.042	0.034	NA	0.039	2.1e-05	1.4e-05	8.6e-05	NA	2.6e-05
12	TCGA	Thyroid Carcinoma	0.1480	0.0470	2.5e-05	0.073	0.065	0.059	NA	0.071	1.2e-07	6.7e-07	1.9e-06	NA	2.0e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.2	0.3	1.1	-0.4	0.8	0.5	0.4	-1.0	0.2	0.4	-0.1	0.5	0.6	-0.6	-0.2
Bipolar Disorder or Schizophrenia	0.4	0.9	5.0	0.6	2.2	0.6	0.9	0.8	0.3	0.9	0.9	1.2	1.0	-0.2	0.3
Depressed Affect (Nagel 2018)	2.2	4.7	17.4	1.2	2.2	-1.4	-0.2	2.0	3.4	3.3	0.8	4.2	1.1	0.8	1.4
Depression (Nagel 2018)	1.2	1.8	7.0	0.8	0.1	-1.0	0.6	1.2	2.2	0.8	1.4	2.6	0.7	1.6	1.1
Intelligence (Savage-Jansen 2018)	0.3	1.1	8.3	0.3	-1.2	-0.7	-0.2	2.9	0.5	-0.8	-0.5	-0.4	-0.3	0.8	0.2
Neuroticism (Nagel 2018)	1.4	3.2	9.7	0.9	2.4	-0.8	0.2	1.7	3.1	3.0	0.2	3.1	0.1	0.4	0.3
Schizophrenia (2018)	0.6	1.3	5.2	1.1	2.3	0.4	0.8	1.9	0.2	0.8	1.1	1.1	1.1	0.1	0.5
Schizophrenia vs Biploar Disorder	0.4	0.6	4.2	-0.1	1.1	-0.7	0.4	2.0	-0.1	-0.0	0.7	0.2	-0.6	-0.2	-0.5
Worry (Nagel 2018)	0.5	1.0	4.8	0.1	1.0	0.6	0.7	-0.3	2.2	1.6	0.1	1.6	-0.7	0.3	-0.4
Alzheimer’s Disease (in mother)	2.0	2.4	7.5	0.9	-1.1	-2.7	-2.7	-0.1	-0.0	-0.9	2.1	0.2	0.4	2.2	1.0
Alzheimer’s Disease (in father)	1.4	1.6	6.6	-0.7	-1.1	0.1	-0.5	-0.5	-2.1	-2.6	0.8	-1.7	-1.0	-0.8	-0.7
Alzheimer’s Disease (including proxy)	1.5	2.2	7.2	1.4	-0.1	-2.0	-2.7	0.1	-1.0	-1.4	2.2	-0.2	0.1	2.2	0.9
Crohns Disease (2017)	1.3	2.9	7.3	-1.0	-1.9	2.3	0.7	-1.6	-1.6	-2.7	-2.2	-1.3	-0.5	-2.0	-1.0
Irritable Bowel Disease (IBD)	0.6	1.5	3.6	-0.4	-1.2	1.9	0.4	-1.4	-1.0	-1.9	-1.5	-0.9	-0.2	-1.5	-0.9
Ulcerative Colitis (UC)	0.1	0.2	1.0	0.1	-0.2	1.0	-0.1	-0.6	-0.1	-0.4	-0.3	-0.2	0.4	-0.5	-0.3
Major Depression (MDD)	0.3	0.4	1.3	-0.3	0.7	-0.1	0.6	0.6	1.1	0.8	0.0	1.0	-0.1	-0.1	-0.2
Reaction Time	0.5	1.0	3.8	0.8	-0.5	-1.1	-1.9	0.2	0.9	-0.1	-0.3	1.9	0.8	-0.1	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.8	0.4	0.2	-0.3	0.0	2.0	1.2	0.6	-1.0	1.0	0.2	0.9	0.7
Breast Cancer	0.2	0.4	1.5	-0.3	1.0	-1.0	-0.1	-0.2	0.3	0.7	-0.9	1.2	0.3	-0.5	-0.1
Ovarian Cancer	0.9	1.2	6.1	-1.0	1.0	-1.6	-2.5	-0.3	-0.7	-0.6	1.0	-0.4	-0.5	-0.5	-1.0
Prostate Cancer	0.4	0.6	2.6	-1.3	-0.7	0.1	0.0	-0.9	-1.6	-0.2	0.4	-1.0	-0.3	-0.6	-0.6
Age at First Birth	0.9	1.3	5.9	0.4	1.2	-1.3	-0.9	-0.7	0.7	0.1	2.4	-0.5	0.0	1.9	-0.3
Bipolar Disorder (2011)	0.6	0.6	2.0	-1.0	0.0	1.0	-0.2	-1.4	-1.0	-0.5	-0.8	-0.3	0.2	-1.2	-0.1
Body Mass Index (BMI) (2010)	2.4	3.3	18.1	0.3	-0.0	-1.8	-2.0	4.3	1.0	0.7	1.8	1.8	1.0	2.2	0.4
Coronary Artery Disease (CAD)	0.5	0.6	4.1	-0.5	0.4	-0.7	-0.7	-0.0	0.5	0.1	1.0	2.0	0.1	0.3	0.5
Crohns Disease (2012)	1.1	1.8	6.8	-0.5	-0.3	2.6	1.3	0.1	-0.4	-1.7	-2.1	-1.0	-0.5	-1.7	-1.2
Mean Putamen Volume	0.7	0.7	4.4	-0.7	0.1	0.2	0.4	2.1	-0.3	0.5	1.6	0.2	0.5	0.8	0.2
Fasting Glucose	0.6	0.7	2.0	-0.6	1.4	0.1	-0.5	-0.2	0.6	1.1	0.9	0.8	1.3	-0.3	0.7
HbA1C	0.9	1.1	2.5	-0.9	-0.5	0.5	0.5	-1.4	-1.0	-0.7	-0.8	-1.2	-1.6	-1.0	-1.4
HDL Cholesterol	0.3	0.5	3.1	-0.3	-1.0	-0.9	-0.4	-1.8	0.4	-0.2	-0.1	0.6	-0.2	-0.7	0.6
LDL Cholesterol	1.1	1.7	5.9	0.4	0.8	-1.3	-1.0	0.7	1.2	1.3	0.2	1.4	2.4	1.3	2.1
Lupus	0.3	0.5	1.5	-0.5	-1.2	0.4	1.2	-0.5	-0.1	1.2	-0.1	-0.3	-0.3	-0.6	0.1
Neuroticism (2016)	2.4	3.5	10.9	1.2	3.3	-0.2	0.9	2.3	2.2	2.6	1.1	2.5	0.8	1.6	1.2
Primary Biliary Cirrhosis	1.4	2.0	4.8	2.1	-0.1	-0.0	-0.9	1.7	-1.3	1.5	1.1	-1.1	1.5	2.2	1.3
Rheumatoid Arthritis	0.3	0.4	1.7	0.3	0.8	0.3	0.5	1.3	-0.1	-0.0	0.3	-0.2	-0.8	-0.8	-0.2
Schizophrenia (2014)	0.6	1.3	4.9	1.0	2.2	1.0	1.3	1.6	0.1	1.1	-0.1	1.2	1.1	-0.5	0.9
Triglycerides	0.3	0.5	1.4	0.6	-0.6	0.5	-0.7	0.6	-1.2	-0.7	0.1	-0.5	1.1	0.3	0.6
Type 2 Diabetes (T2D) (2012)	1.0	1.1	7.1	-0.9	0.1	0.8	0.2	0.1	0.4	0.7	-2.7	0.5	-0.6	-1.7	-0.7
Ulcerative Colitis	0.5	0.8	3.3	-0.5	-0.4	1.0	-0.1	-0.8	-0.9	-1.8	-0.6	-0.9	-0.7	-0.3	-1.1
Blood Eosinophil Count	0.1	0.7	1.7	1.0	1.3	-0.7	-0.7	1.2	0.2	0.9	1.2	0.6	-0.5	-0.1	0.4
Blood Platelet Count	0.2	2.2	5.5	0.1	1.0	0.0	0.4	1.3	-0.6	1.9	2.3	-1.4	2.0	2.4	1.4
Blood Red Count	0.1	0.9	3.0	1.7	1.6	0.3	-0.2	-0.0	1.2	-0.4	-1.4	0.6	0.4	-0.4	0.7
Blood White Count	0.3	2.4	9.0	2.0	1.8	-1.9	-1.4	1.2	0.2	1.0	3.0	-0.0	0.8	1.8	1.2
Heel T-Score	0.3	2.3	10.6	0.3	2.3	1.5	0.7	3.3	-1.8	0.2	1.1	-0.5	0.6	1.9	-0.2
BMI	1.7	9.7	34.9	3.1	-0.3	-2.8	-1.5	5.9	2.9	2.8	2.6	3.5	3.5	2.7	2.6
Height	0.2	4.1	13.3	-1.2	0.4	0.2	2.1	2.9	1.9	1.7	-2.8	2.5	0.4	-3.6	-0.5
Waist Hip Ratio (WHR)	0.3	1.2	9.4	-0.5	1.5	0.0	-1.3	-3.1	-0.6	-0.6	0.0	-0.7	-0.5	-0.1	0.2
Systolic Blood Pressure	1.5	7.3	63.4	0.2	1.7	1.7	0.2	-8.0	-0.2	-1.0	-2.3	-1.4	-1.9	-2.0	-1.6
Smoking Status	1.3	3.2	10.1	2.1	-0.9	-3.1	-2.5	-3.2	0.4	-2.0	-1.2	0.9	-0.8	-0.5	0.6
Allergy or Eczema	1.6	4.2	9.3	1.8	-0.1	-1.0	-0.6	0.1	2.8	3.1	2.0	2.9	1.6	2.5	2.8
Cardiovascular Disease	0.2	0.5	5.0	-0.3	0.4	0.4	-0.4	-2.2	-0.0	-0.8	0.1	-0.3	0.0	-0.2	-0.2
Hypothyroidism (self reported)	0.3	0.7	2.1	-1.0	-1.3	0.7	0.1	0.0	-0.8	-1.4	-0.2	-0.0	-0.2	-1.3	-0.8
Respiratory disease	0.2	0.5	1.6	0.1	0.2	-0.4	-0.3	-1.1	0.3	-0.0	-1.1	0.7	0.3	-1.3	0.5
Type 2 Diabetes (T2D) (2018)	1.4	2.7	6.0	2.4	1.3	-0.7	-0.7	2.4	0.9	1.6	-0.7	1.9	1.2	1.7	2.4
Lung FEV1/FVC ratio	0.5	2.5	13.7	-0.6	-2.0	0.1	0.8	3.7	-2.1	-1.1	1.8	-0.4	0.5	1.5	-0.1
Lung FVC	0.5	2.6	11.2	0.1	-1.8	-0.5	-1.3	3.4	-1.4	0.1	2.2	0.3	2.2	0.8	1.5
Neuroticism	1.3	3.1	9.4	0.8	2.8	0.1	0.3	1.7	2.8	3.1	-0.3	2.8	0.3	0.6	0.2
Chronotype (morning person)	0.8	1.9	7.3	-1.6	-1.9	-0.4	0.2	-2.7	-1.3	-1.3	0.4	-1.2	-1.2	-1.3	-1.1
Hair Pigment	0.0	0.9	3.8	0.2	-0.2	-0.2	-1.5	1.3	-0.1	0.7	1.5	0.0	0.6	1.9	0.1
Tanning	0.1	0.8	2.2	0.9	1.5	-1.5	-1.4	-0.4	0.4	0.2	0.7	1.0	0.1	0.5	0.8
Hand grip strength (left)	1.3	3.5	9.7	0.9	-1.9	3.1	1.4	-0.2	-2.3	-2.5	-2.8	-1.8	0.6	-1.7	-0.7
Number of treatments/medications taken	0.5	0.9	2.6	-1.6	-0.3	-0.3	1.4	-1.6	0.5	-0.9	0.3	0.5	-1.0	-0.4	-1.0
Average weekly spirits intake	0.7	0.9	3.4	-0.8	-0.3	-0.0	0.1	0.8	-0.0	-1.0	0.2	-0.7	-1.5	-1.3	-1.8
Sensitivity / hurt feelings	0.7	1.2	4.6	1.0	2.1	0.1	0.3	2.0	0.9	0.9	-0.2	0.4	-1.1	0.7	-1.3
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.9	0.3	-0.2	-1.1	-0.2	1.7	-0.0	-0.6	0.9	0.1	-0.1	1.0	-0.3
Hearing difficulty/problems: Yes	1.2	1.9	7.1	-1.7	-1.7	0.6	1.0	-0.7	-1.1	-1.5	-1.2	-0.9	-0.4	-2.7	-1.4
Relative age of first facial hair	0.8	1.6	8.5	0.4	-0.4	1.3	-0.6	0.7	-0.7	0.3	1.4	-0.6	1.6	2.9	1.7
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.8	-1.4	-0.8	0.7	0.7	0.8	0.2	-0.6	-0.2	0.0	-0.8	-0.3	-1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.3	0.2	-0.3	-0.6	0.1	-0.6	0.3	-0.6	1.1	0.1	-1.5	-0.1	-0.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.7	-0.6	0.6	0.3	-0.5	-0.6	-0.1	-0.6	0.3	0.2	-0.5	-1.3	-0.2
Systolic blood pressure, automated reading	0.6	1.7	12.3	1.1	0.8	-0.6	-0.6	-3.5	1.2	0.8	0.8	0.9	0.5	1.0	0.9
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	3.3	0.8	-0.7	-0.4	-1.8	-1.3	0.5	0.4	-1.2	0.6	0.4	0.0	0.5
Angina	0.9	1.1	2.6	-0.0	-1.1	1.2	1.3	-1.2	-0.2	-1.6	-1.3	0.3	-1.3	-1.3	-0.6
Medication for hormone replacement therapy	1.6	1.7	6.7	-1.8	-0.2	0.6	0.8	-1.2	0.0	-0.2	0.2	-0.3	-2.2	-2.6	-1.8
Vitamin and mineral supplements	0.5	0.6	3.8	-0.3	0.2	-0.1	-0.9	-1.9	-0.1	-0.4	-1.0	-0.3	0.1	-1.0	-0.6
Supplements: Zinc	1.0	1.1	3.6	-1.2	-1.5	0.0	1.0	-0.6	0.3	0.0	-1.3	0.0	-1.7	-1.9	-0.3
Medication: Co-codamol	1.1	1.3	7.0	-0.2	0.2	-0.8	-0.3	0.2	1.8	1.4	0.4	2.6	0.9	0.3	1.3
Medication: Metformin	0.7	0.9	8.4	0.3	0.0	-0.8	-0.4	2.9	0.9	0.4	-0.5	0.7	-0.0	0.4	0.4
Diabetes (father)	1.5	1.8	6.9	-0.6	-1.6	-2.2	-1.9	-2.6	0.5	-0.7	0.3	-0.8	-0.9	-0.7	-0.9
Diabetes (mother)	0.7	0.9	3.0	-0.9	0.2	0.9	1.7	1.4	0.2	0.1	-0.8	-0.2	-0.4	-1.7	-1.0
Severe depression (siblings)	0.3	0.4	1.2	0.5	0.7	-1.1	-0.6	1.1	0.8	0.4	-0.6	0.1	0.1	-0.1	0.1
Pack years adult smoking proportion	1.2	1.8	5.7	-1.1	-0.6	-1.9	-1.8	-0.8	-0.5	-1.4	-0.8	-0.7	-1.4	-2.4	-1.1
Impedance of leg (right)	1.0	5.0	19.5	-0.5	4.4	4.0	1.8	-1.2	-2.6	-0.1	-0.1	-3.1	-1.3	0.8	-1.0
Leg fat-free mass (left)	1.1	5.7	14.9	0.7	-1.6	-3.6	-1.7	3.6	3.4	1.6	0.4	3.9	2.0	-0.9	1.4
Trunk fat percentage	1.2	4.6	20.0	2.4	1.2	-1.3	-0.7	4.5	1.9	2.2	1.6	1.7	2.0	2.1	2.0
Hand grip strength (right)	0.7	1.9	5.3	0.1	-1.9	1.8	1.0	0.2	-1.6	-2.3	-2.1	-1.1	-0.2	-1.2	-0.8
Townsend deprivation index at recruitment	0.9	1.2	4.2	0.7	0.7	-2.1	-1.4	-0.4	1.4	0.6	0.5	1.8	1.0	0.4	0.8
Current tobacco smoking	1.2	1.9	5.4	0.3	-1.5	-2.3	-1.0	-1.4	1.6	-2.0	-0.9	1.1	-1.3	-1.6	-0.2
Average weekly fortified wine intake	0.4	0.4	2.7	0.4	-0.1	-0.5	-1.6	-0.7	-0.8	-0.4	0.2	-0.1	-0.9	-0.2	-0.1
Maternal smoking around birth	2.3	3.3	11.2	-1.7	-1.3	1.2	0.7	-2.1	0.2	-2.1	-3.3	-0.2	-0.8	-3.4	-1.0
Fed-up feelings	2.0	3.7	9.3	1.8	2.5	-0.7	0.1	2.2	2.7	3.0	-0.2	2.4	1.8	1.5	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	2.9	0.8	-1.1	-1.2	-0.1	1.5	0.9	-0.4	0.1	1.7	0.6	0.5	0.6
Relative age voice broke	1.1	1.7	7.5	0.6	1.0	-0.2	-2.1	-0.3	0.3	1.0	1.4	0.2	1.2	2.7	1.6
Taking other prescription medications	0.2	0.3	1.6	-0.5	0.2	0.3	1.2	0.8	0.7	0.0	0.0	0.3	-0.2	-0.3	-0.3
Age when periods started (menarche)	0.3	0.7	2.5	-0.3	-0.3	-0.0	-0.3	-1.1	-1.0	-0.9	0.7	-1.6	-0.8	1.0	-0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.8	0.4	-0.0	0.4	1.3	0.5	0.0	-0.5	-1.1	0.0	-1.4	-1.2	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	5.6	1.0	0.5	-0.1	-0.2	2.4	-1.3	-0.0	1.6	-1.1	0.4	1.6	0.4
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.6	-0.2	-0.9	-1.9	-1.6	-1.4	-0.2	-1.1	0.6	-0.1	0.2	0.9	0.0
Qualifications: CSEs or equivalent	0.3	0.4	2.0	-0.5	0.0	-0.4	-0.8	-1.4	0.5	-0.5	-0.1	-0.3	-0.1	-0.9	-0.8
Serious illness, injury or assault to yourself	0.5	0.6	1.8	-0.7	0.3	1.3	1.1	0.1	0.6	1.2	-0.3	0.3	0.5	-1.3	0.0
High blood pressure	0.1	0.4	1.7	0.4	-0.0	-0.3	0.1	-1.3	0.5	-0.5	0.6	0.3	0.9	1.0	0.4
Hayfever, allergic rhinitis or eczema	1.5	3.3	7.2	2.3	-0.9	-1.1	-0.9	-0.4	2.3	2.4	0.5	2.4	1.5	2.1	2.7
Multivitamins +/- minerals	0.5	0.7	4.0	0.2	0.2	-0.2	0.7	2.0	0.4	0.7	1.1	0.0	0.2	1.1	0.4
Stomach or abdominal pain in last month	0.3	0.4	1.5	-0.2	-0.3	-1.2	-1.0	-0.3	0.1	0.0	0.9	0.8	-0.2	0.4	0.6
Supplements: Glucosamine	0.4	0.5	1.9	-1.4	-1.0	-0.4	-0.1	-0.4	0.3	-0.7	0.5	0.6	-0.5	0.6	-0.8
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.3	-1.4	0.2	1.4	1.8	0.7	-0.9	-1.1	0.3	-0.9	-0.7	-1.5	-1.8
Medication: Atenolol	0.7	0.9	2.8	0.3	1.5	1.2	1.1	-0.1	1.7	0.8	-1.3	0.5	-0.4	-0.3	0.0
Medication: Levothyroxine sodium	0.2	0.4	1.4	-0.4	-0.2	0.8	-0.1	-0.2	-0.7	-1.2	0.4	-0.2	-0.7	-0.9	-0.8
Sitting height	0.2	1.2	6.9	-1.2	-0.0	-0.2	0.9	1.4	0.8	0.4	-1.2	1.0	0.1	-2.6	-0.5
Chronic bronchitis/emphysema (father)	2.4	2.8	10.1	-1.5	1.8	1.5	1.9	-0.5	1.1	0.7	-2.7	1.1	-0.7	-3.2	-1.0
High blood pressure (mother)	0.1	0.1	0.4	-0.3	0.3	0.6	-0.1	0.4	-0.7	0.1	-0.2	-0.0	0.3	0.2	0.2
Body mass index (BMI)	2.4	10.2	22.3	3.0	-0.7	-3.6	-2.1	4.7	3.6	2.9	2.6	4.0	3.6	2.6	3.3
Impedance of leg (left)	1.2	5.8	20.0	-0.5	4.2	4.5	2.4	-1.8	-2.8	-0.2	-0.3	-3.4	-1.2	0.8	-1.0
Leg predicted mass (left)	1.0	5.5	14.4	0.7	-1.7	-3.6	-1.7	3.6	3.3	1.6	0.4	3.8	1.9	-0.9	1.4
Trunk fat mass	1.3	5.6	25.3	2.1	0.4	-2.1	-1.1	5.0	2.4	2.2	1.7	2.4	2.3	1.6	2.0
Waist circumference	1.7	6.1	15.6	2.2	0.3	-2.2	-1.2	4.0	2.9	2.3	1.8	3.3	3.0	1.9	2.5
Number of incorrect matches in round	0.5	0.8	2.0	-0.5	-0.5	0.8	1.4	-1.4	0.3	0.3	-1.0	0.9	-0.6	-1.3	-0.5
Past tobacco smoking	0.5	1.0	3.2	-1.6	0.1	1.8	1.2	1.2	-0.6	0.7	0.8	-0.4	-0.1	-1.0	-0.6
Alcohol usually taken with meals	0.6	0.9	4.8	0.0	-0.2	-0.4	0.2	1.6	-0.3	0.0	1.8	-0.5	-0.1	2.2	0.2
Nervous feelings	1.5	2.9	13.2	0.2	3.6	2.2	2.3	1.7	1.5	1.6	-0.8	0.8	-0.6	-0.2	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.5	3.6	0.1	0.1	0.5	0.5	1.9	0.8	0.0	-0.7	1.0	-0.2	0.5	0.2
Hearing difficulty/problems with background noise	1.6	2.5	7.0	-1.6	-0.1	2.6	2.7	2.4	-0.3	-0.4	-1.8	-0.2	0.5	-1.7	-1.2
Hair/balding pattern: Pattern 2	0.9	1.1	3.1	1.4	0.4	-0.7	-1.8	-1.6	-1.6	-0.5	0.8	-1.0	0.2	0.9	0.5
Had menopause	0.5	0.6	1.5	0.6	0.5	1.0	0.9	1.2	1.0	0.4	0.5	1.2	-0.1	0.3	0.2
Had other major operations	0.9	1.1	5.5	0.0	1.1	0.7	1.1	2.3	0.7	1.1	0.9	0.6	0.8	0.8	0.6
Forced vital capacity (FVC)	0.2	0.9	3.0	-1.3	-1.0	0.3	-0.4	1.7	-1.5	0.5	1.0	-0.3	0.8	-1.0	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	7.5	1.0	0.8	-0.0	-0.0	2.7	-1.2	0.1	1.6	-0.9	0.1	1.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.7	-0.4	0.1	-1.3	-0.1	-1.1	0.9	0.9	0.2	1.2	-0.0	-0.1	0.3
Qualifications: None of the above	0.6	1.3	2.9	1.0	-0.1	-1.7	-0.8	-1.6	1.0	0.5	0.8	1.5	1.3	0.8	1.5
Financial difficulties in last 2 years	0.4	0.5	1.5	0.9	-0.2	-0.6	0.7	-0.6	0.7	0.7	-0.8	1.2	0.3	-0.1	1.0
Mouth/teeth dental problems	0.3	0.5	2.0	0.3	-0.6	0.8	0.6	1.1	-0.6	0.1	-0.5	-0.2	1.4	-0.5	0.5
Heart attack	0.4	0.5	1.4	0.7	0.4	0.8	1.1	0.3	0.9	1.2	-0.1	0.9	-0.2	-0.1	0.7
Allergy	0.8	1.8	4.7	-1.3	1.2	1.5	0.8	0.9	-2.2	-1.1	0.0	-2.2	-0.6	-0.3	-1.8
Pain all over the body in last month	0.6	0.7	3.1	-1.4	0.5	-0.5	-0.1	-0.2	1.0	0.0	-0.8	0.7	0.2	-1.8	-0.6
Diabetes (self-reported)	1.2	1.8	4.2	1.4	1.0	-1.3	-1.3	2.0	1.8	1.3	-0.6	1.9	0.2	1.2	1.3
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	5.8	0.3	-2.4	-0.9	-0.1	-0.7	0.1	-0.6	0.8	-0.3	-0.8	0.7	0.3
Medication: Ramipril	0.7	0.9	4.6	1.3	-1.3	0.9	1.0	-0.5	0.8	-0.6	-2.1	-0.1	0.0	-0.4	-0.2
Medication: Simvastatin	0.3	0.4	1.5	-1.2	-0.1	0.2	0.0	-0.4	0.4	-0.1	0.8	-0.6	-1.2	0.5	-0.5
Fluid intelligence score	0.3	0.6	2.6	0.1	0.8	-0.2	-0.7	1.2	0.4	0.7	-1.6	0.7	-0.5	-0.3	0.2
Illnesses of siblings	0.4	0.6	2.0	0.7	0.7	0.1	-1.4	0.9	-0.9	-0.3	-1.2	-0.7	0.3	-0.3	-0.1
Neuroticism score	1.1	2.4	7.3	1.1	2.7	-0.4	-0.1	2.1	2.3	2.2	-0.0	2.2	-0.0	0.4	-0.0
Weight	1.6	8.0	28.5	1.9	-0.5	-2.9	-1.1	5.3	3.6	2.7	1.5	3.9	3.1	1.0	2.3
Impedance of arm (right)	1.3	5.8	16.0	-0.8	2.4	3.6	1.8	-0.9	-3.2	-1.8	-2.1	-4.0	-2.6	-1.1	-2.1
Arm fat percentage (right)	1.6	6.2	24.3	2.8	0.2	-2.3	-1.8	4.9	2.3	1.9	2.0	2.1	2.4	2.2	2.4
Trunk fat-free mass	0.8	4.7	12.7	-0.1	-2.1	-3.4	-1.4	2.9	3.0	1.2	0.6	3.6	1.8	-1.1	0.9
Hip circumference	2.1	9.0	36.2	2.9	-0.2	-2.0	-0.4	6.0	2.9	2.9	2.3	3.4	3.6	2.3	2.8
Time employed in main current job	0.5	0.6	2.4	-0.8	0.1	-1.5	-0.3	-0.4	0.8	0.7	1.5	0.4	0.1	0.3	-0.0
Alcohol intake versus 10 years previously	1.1	1.7	6.6	2.6	0.1	-1.4	-1.0	-0.9	0.8	1.5	0.1	2.0	1.2	0.0	1.4
Father’s age at death	0.8	1.1	2.7	-0.4	-1.5	1.6	1.6	1.1	-1.0	-0.5	-1.3	-0.9	-0.4	0.1	-0.6
Worrier / anxious feelings	0.6	1.1	3.1	0.4	1.3	0.5	0.8	1.4	1.4	1.2	1.0	1.1	-0.1	1.8	-0.3
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	10.3	-0.4	0.6	-3.2	-1.7	1.8	1.9	0.5	1.0	2.6	0.3	0.9	1.1
Falls in the last year	1.7	2.4	8.1	-0.2	0.6	-2.5	-1.2	0.8	2.2	1.4	1.0	2.9	0.5	1.2	1.4
Hair/balding pattern: Pattern 3	0.8	1.2	3.5	-1.4	-1.5	1.9	0.8	0.9	-1.1	-0.8	-1.0	-0.8	0.9	-0.8	-0.3
Number of live births	1.5	2.2	4.3	0.1	-0.7	-0.2	-0.5	2.0	2.1	1.7	1.3	1.6	2.1	1.2	1.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.0	-1.2	-1.2	0.3	-0.6	2.1	-2.2	0.3	1.5	-0.4	0.8	-0.4	0.1
Pulse rate	0.2	0.4	1.2	0.5	-0.2	0.6	1.1	-1.0	-0.3	-0.2	-0.5	-0.8	0.6	-0.1	0.6
Happiness	1.5	1.9	5.1	2.2	1.1	-0.8	-0.1	1.8	1.2	1.7	0.6	1.0	0.7	2.1	1.4
Noisy workplace	0.4	0.5	1.8	-0.5	-1.1	-0.3	-0.0	-0.9	0.3	-0.7	-0.1	-0.1	-1.3	-0.7	-0.6
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.5	-0.5	-1.2	0.5	1.3	0.6	-1.1	-1.3	-1.9	-1.4	-1.4	-1.2	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.5	1.2	0.8	-0.5	-0.4	-0.7	0.1	1.1	1.2	0.4	-0.1	1.6	0.1
Mouth/teeth dental problems: Dentures	1.2	2.0	12.5	1.2	1.3	-0.1	-0.3	-3.5	1.8	0.7	-0.8	0.1	-2.1	0.3	-0.4
Asthma	0.3	0.6	3.1	0.0	-0.6	-0.8	-0.3	-1.4	-0.2	-0.6	-0.8	0.2	-0.4	-1.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	7.5	-0.9	2.0	-2.0	-0.3	-0.1	2.3	0.9	0.8	2.7	0.1	0.0	-0.1
Medication: Cholesterol lowering	1.5	2.3	6.7	-2.6	-0.8	1.5	1.8	-1.0	-0.8	-1.6	-0.7	-1.4	-1.8	-1.3	-1.8
Depression (self-reported)	1.4	1.7	4.2	0.2	1.8	0.5	1.8	0.4	1.9	1.3	-1.6	2.0	0.5	-0.7	0.2
Medication: Lansoprazole	0.9	1.0	3.0	0.5	1.1	-1.2	-0.1	0.6	1.7	-0.1	1.0	1.0	-1.5	0.7	-0.9
Prospective memory result	0.5	0.6	1.7	0.7	-0.0	-0.4	-0.1	0.7	0.7	0.9	1.3	0.8	0.8	0.6	1.0
Lung cancer (father)	0.4	0.5	3.6	1.9	0.7	-0.5	-0.2	-0.4	-0.3	0.3	-0.3	-0.3	0.4	0.5	0.5
Illnesses of mother	0.5	0.7	2.2	0.9	1.5	0.3	0.3	-0.9	1.2	1.1	-0.3	0.9	0.6	0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.4	4.6	-1.8	-1.2	0.5	-0.5	2.2	-1.9	-0.2	1.3	-0.4	-0.2	-1.0	-0.7
Pulse wave Arterial Stiffness index	0.3	0.4	1.2	-0.3	-0.3	0.7	0.4	0.7	-0.1	-0.4	-1.1	-0.8	-0.5	-0.8	-0.6
Impedance of arm (left)	1.4	6.5	15.8	-1.4	2.2	3.8	2.1	-1.1	-3.0	-1.7	-1.7	-4.0	-3.3	-1.4	-2.8
Arm fat mass (right)	1.8	7.5	26.1	2.6	-0.3	-2.9	-1.8	5.1	2.8	2.4	2.2	3.0	2.9	1.9	2.6
Trunk predicted mass	0.8	4.6	12.5	-0.1	-2.1	-3.5	-1.5	2.8	3.0	1.2	0.6	3.5	1.9	-1.1	1.0
Standing height	0.3	2.5	11.5	-2.1	0.1	0.7	1.7	1.8	0.5	0.1	-1.8	0.5	-0.7	-3.4	-1.7
Length of working week for main job	0.6	0.6	2.3	0.5	1.5	-0.5	-0.3	1.2	0.5	0.6	0.3	1.0	0.4	-0.0	1.2
Exposure to tobacco smoke at home	0.7	0.8	3.1	-0.5	0.0	-1.8	-0.8	-0.8	1.2	-0.0	1.3	0.9	-0.7	0.6	0.0
Breastfed as a baby	0.3	0.4	0.8	0.8	0.9	0.4	0.0	0.4	-0.9	-0.9	-0.4	-0.7	-0.8	0.2	0.1
Tense / ‘highly strung’	0.6	1.0	3.2	0.8	0.9	-1.5	-1.1	-0.0	1.8	1.1	-0.2	1.3	-0.8	0.3	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.1	-0.4	0.7	0.8	1.4	-0.4	0.5	0.5	-0.5	0.1	-0.9	-0.6	-1.2
Hair/balding pattern: Pattern 4	0.4	0.9	2.3	0.9	1.4	-0.4	-0.3	1.1	1.0	0.9	1.0	1.5	0.0	0.9	0.7
Birth weight of first child	0.3	0.6	2.5	-0.6	-0.1	-1.4	-1.6	-0.5	0.2	0.4	0.6	0.0	0.3	0.7	0.7
Peak expiratory flow (PEF)	0.2	0.5	2.1	-0.2	0.1	-0.7	-1.2	0.6	-1.5	0.5	1.1	0.3	0.2	0.1	0.2
Pulse wave reflection index	0.6	0.8	3.4	-0.2	-0.0	1.4	1.3	1.8	0.0	0.7	-0.6	0.6	1.0	-0.3	0.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	6.2	-0.8	1.0	-1.0	-0.5	0.9	2.5	0.4	1.1	1.8	-0.0	0.8	0.2
Loud music exposure frequency	0.4	0.5	1.2	0.8	0.4	-1.0	-1.1	0.2	0.8	0.3	-0.2	1.1	-0.3	-0.4	0.5
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	5.9	0.0	0.2	0.2	0.9	0.3	-1.3	-0.5	0.7	-2.4	-1.5	-0.8	-2.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.5	-0.1	0.8	-1.4	-0.9	1.6	-0.2	0.5	1.4	-0.4	-0.4	0.9	-0.1
Blood clot in the leg (DVT)	1.0	1.3	4.8	2.1	0.5	1.2	1.1	0.3	0.5	0.9	-2.2	0.5	0.8	0.1	1.5
Medication: Paracetamol	0.4	0.7	1.8	-0.4	-0.1	0.2	0.5	-1.4	1.4	1.0	0.3	1.2	1.0	0.6	0.5
Headache pain in last month	0.2	0.3	1.1	0.1	-0.3	-0.2	-0.3	-0.9	1.1	1.0	-0.7	0.6	-0.1	0.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.8	1.7	0.6	-1.0	-1.2	1.4	0.2	1.1	0.5	0.4	1.4	0.8	1.4
Glaucoma (self-reported)	0.6	0.7	2.9	0.6	0.2	-1.1	-1.7	-1.2	-0.6	0.1	0.7	-0.4	-0.5	0.7	0.4
Gout (self-reported)	0.5	0.7	3.6	0.5	-0.4	-1.0	-0.2	-1.9	-0.0	0.6	-0.7	0.8	0.3	-0.2	1.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.5	-0.6	-0.6	0.6	0.2	0.6	-0.5	-1.2	0.4	0.2	-0.2	-0.3	-0.8
Medication: Amlodipine	0.4	0.6	2.1	-1.0	-0.3	0.4	0.7	-0.1	1.2	-0.5	1.4	0.2	0.5	1.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.8	-0.9	-0.7	-0.7	0.5	0.2	-0.3	0.3	-0.2	0.4	0.6	0.5
Birth weight	0.4	0.9	3.1	-0.8	-1.8	0.1	-1.2	-1.0	-1.3	-0.9	-0.6	-0.4	-0.5	-0.7	-0.4
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.8	0.1	1.3	-0.1	1.0	-0.0	1.5	1.0	-0.7	1.7	-0.6	-1.0	0.2
High blood pressure (siblings)	0.8	1.1	2.5	-1.3	-1.2	0.7	1.6	-0.9	-0.3	-0.6	0.4	-1.0	-1.5	-0.4	-1.4
Forced vital capacity (FVC), Best measure	0.3	1.1	3.8	-1.9	-0.9	0.5	-0.4	1.5	-1.3	0.1	0.6	-0.4	-0.3	-1.8	-0.8
Body fat percentage	1.6	6.4	22.8	2.7	1.3	-1.6	-1.1	4.8	2.3	2.5	2.1	2.2	2.6	2.7	2.6
Leg fat percentage (right)	2.4	8.8	26.5	3.0	1.7	-1.8	-1.2	5.2	2.5	2.8	3.1	2.6	3.0	3.7	2.9
Arm fat-free mass (right)	0.9	4.8	14.3	0.1	-1.8	-3.3	-1.4	2.5	3.2	1.7	1.2	3.8	2.1	-0.6	1.4
Exposure to tobacco smoke outside home	2.0	2.6	8.5	-1.0	0.1	2.4	2.5	-0.7	-1.2	-0.8	-2.9	0.0	-1.0	-2.3	-0.8
Comparative body size at age 10	1.0	2.8	11.8	-0.4	-1.4	-0.3	1.2	3.4	2.4	1.2	-0.2	3.1	1.0	0.2	0.6
Number of full brothers	0.3	0.3	1.8	-1.0	-1.4	-0.2	-0.3	-0.1	-0.1	-0.2	-0.2	0.3	0.1	-1.0	-0.2
Worry too long after embarrassment	1.3	2.2	6.9	0.1	1.4	-1.7	-0.4	2.6	2.2	2.2	-0.2	2.0	-0.8	0.1	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	4.3	-1.0	0.8	0.3	0.9	-1.5	1.1	-0.0	-1.1	0.4	-1.6	-1.9	-2.1
Wheeze or whistling in the chest in last year	0.8	1.5	6.5	0.5	-1.5	-2.5	-0.7	-0.9	1.8	-0.5	0.7	1.4	0.2	-0.5	1.1
Number of children fathered	1.1	1.2	3.1	0.3	-1.5	-1.8	-0.9	1.4	-0.0	-1.7	1.4	-0.4	-1.1	0.4	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.5	-0.0	-1.9	1.5	1.1	-0.6	-1.0	-1.3	-0.5	-1.1	0.1	0.2	-0.3
Age at first live birth	0.9	1.6	5.6	-2.4	-1.0	0.4	-0.1	-1.0	-1.2	-1.6	0.7	-1.5	-1.1	0.1	-2.0
Pulse wave peak to peak time	0.3	0.3	0.9	0.3	0.2	-0.8	-0.5	-0.4	0.2	0.4	0.9	0.8	0.5	0.5	0.5
Health satisfaction	0.2	0.2	1.0	0.1	0.1	-0.0	0.5	-0.4	0.3	0.1	-1.0	-0.1	-0.4	-0.9	-0.1
Shortness of breath walking on level ground	1.1	1.3	5.8	0.9	-0.2	0.1	1.0	0.4	2.4	1.0	-0.5	1.7	1.2	0.5	1.5
Qualifications: College or University degree	0.2	0.6	4.0	0.8	-0.2	0.2	-0.7	2.0	-1.0	-0.0	-0.8	-0.3	-0.4	0.5	-0.3
Eye problems/disorders: None of the above	0.7	0.8	2.7	-1.4	-1.7	-0.0	0.9	0.9	-0.3	-1.1	0.3	-0.9	0.1	0.5	-1.0
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.0	-1.0	-0.6	-0.2	0.4	1.1	0.3	-0.8	-0.5	1.2	-0.1	-1.4	0.0
Emphysema/chronic bronchitis	1.1	1.3	4.6	-1.1	-0.2	-1.1	-1.1	-1.0	0.1	-1.1	-0.3	0.1	-1.6	-2.1	-1.4
Medication for pain relief, constipation, heartburn	0.3	0.4	1.8	0.9	-0.6	0.1	-0.9	-0.3	-0.2	-0.4	0.3	-1.3	-0.9	-0.4	-0.0
Neck or shoulder pain in last month	0.3	0.4	2.1	0.4	0.5	-0.1	0.1	-0.5	0.1	0.2	0.7	0.8	0.2	1.4	0.8
Medication: Blood pressure	0.3	0.6	2.1	-0.8	-0.9	-0.4	-0.2	-1.4	0.6	-0.6	1.0	0.0	-0.8	0.4	-0.6
Angina (self-reported)	0.9	1.2	3.1	-0.2	-1.2	1.0	1.2	-1.4	-0.2	-1.7	-1.1	0.4	-1.5	-1.3	-0.6
Migraine (self-reported)	1.4	1.7	6.4	-1.1	-1.1	2.1	2.5	-0.9	-0.4	-0.1	-0.2	-1.8	-1.1	-0.1	-1.3
Medication: Ibuprofen	1.7	2.0	5.6	-1.3	1.7	-2.4	-0.9	-0.5	2.2	0.7	1.3	2.3	-0.5	-0.1	-0.5
Medication: Allopurinol	0.6	0.8	3.8	0.0	-0.3	-0.4	0.6	-2.0	-0.3	-0.2	-1.6	0.0	-0.7	-1.5	-0.2
Medication: Omeprazole	0.9	1.1	2.8	0.3	-0.0	-1.7	-1.6	1.3	0.1	1.0	0.3	1.2	0.9	0.5	1.3
Medication: Seretide 50 evohaler	1.3	1.5	4.0	-0.2	-1.2	0.5	0.3	-1.3	-1.0	-1.0	-1.7	-1.2	-1.5	-2.0	-1.3
Mean time to correctly identify matches	0.5	1.0	4.0	0.8	-0.7	-1.0	-1.2	0.9	0.9	-0.2	-0.1	2.0	1.1	0.5	1.3
Heart disease (mother)	0.4	0.5	1.9	-0.4	-1.4	-0.8	-0.3	1.0	0.0	-1.0	0.7	0.1	-0.7	-0.2	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.7	0.0	-1.0	-1.5	-1.6	-0.1	-0.6	-0.1	0.5	0.1	0.1	1.2	1.2
Whole body fat mass	1.8	7.3	28.7	2.6	0.5	-2.4	-1.4	5.4	2.5	2.5	2.1	2.7	3.0	2.2	2.6
Leg fat mass (right)	2.7	10.3	29.4	3.0	0.7	-2.9	-1.8	5.4	3.1	3.0	2.8	3.5	3.7	2.9	3.4
Arm predicted mass (right)	0.9	4.4	13.9	0.1	-1.6	-3.1	-1.4	2.4	3.1	1.7	1.1	3.7	2.0	-0.6	1.2
Pulse rate, automated reading	0.3	0.8	1.8	-0.8	-1.2	0.7	0.3	-1.0	-0.5	-1.2	-1.1	-0.9	0.3	-1.4	-0.6
Alcohol intake frequency.	0.5	1.2	4.0	1.9	0.5	-0.7	-0.3	-0.6	1.3	2.0	-0.2	1.8	0.3	-0.6	0.7
Comparative height size at age 10	0.8	4.2	22.5	-2.1	-1.7	1.5	2.5	-0.2	-0.2	0.0	-3.3	0.4	-0.5	-4.7	-0.8
Number of full sisters	0.9	1.1	2.8	1.7	0.6	-1.0	-1.3	1.1	0.6	1.1	0.1	1.0	1.3	0.6	1.2
Suffer from ‘nerves’	0.7	1.1	4.0	-1.4	0.4	-0.1	-0.6	-1.1	0.7	0.5	0.6	0.6	-1.9	-0.5	-2.0
Overall health rating	0.6	1.2	5.4	-0.3	0.0	-1.4	-0.6	1.3	1.8	0.4	0.3	2.3	1.1	0.2	0.9
Chest pain or discomfort	0.4	0.6	3.4	0.9	0.5	-1.8	-1.0	-0.0	0.9	0.9	0.3	0.3	-0.5	0.3	0.5
Had major operations	1.6	1.8	4.8	-1.1	-0.5	1.5	0.8	1.0	-1.8	-2.2	-1.7	-1.1	-1.0	-0.7	-1.8
Age at last live birth	0.8	1.2	5.0	-2.2	-1.1	-0.2	-0.2	-0.8	-0.1	-1.2	0.2	-0.1	-1.4	-0.8	-1.9
Family relationship satisfaction	1.2	1.5	4.3	1.6	0.9	0.1	1.0	2.1	0.7	1.5	-0.4	0.9	1.5	1.0	1.7
Leg pain on walking	1.4	1.8	7.8	-0.0	0.6	-0.6	0.4	0.4	2.4	1.8	-0.2	2.8	1.4	0.5	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.7	-0.8	0.7	1.0	1.8	0.1	-0.6	-1.3	-1.9	-0.9	-0.7	-1.7	-1.4
Commuting to job workplace: Car/motor vehicle	3.2	3.7	9.1	-1.6	-0.7	3.0	3.0	0.6	-2.2	-1.7	-1.1	-2.4	-1.1	-2.0	-1.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.3	-0.2	-0.2	0.1	-0.2	-0.4	-0.6	-0.3	-1.2	-0.3	0.5	-0.6	0.5
Medication: Aspirin	0.9	1.2	4.9	-1.3	-2.0	-0.3	0.1	0.5	-1.2	-2.2	0.1	-0.7	-0.4	-0.0	-1.0
Supplements: Vitamin C	0.5	0.6	1.8	-0.8	-0.3	0.3	0.0	1.2	0.6	-0.1	0.6	0.3	-1.3	-1.1	-1.3
Knee pain experienced in last month	0.7	1.1	3.8	1.3	0.2	-0.3	0.4	0.5	0.0	0.7	-0.3	0.8	1.6	1.7	1.9
Hypertension (Self-reported)	0.2	0.6	2.2	0.7	-0.1	-0.6	-0.4	-1.2	0.6	-0.5	0.7	0.3	1.1	1.5	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.2	0.6	1.5	-1.3	-0.6	0.5	0.8	0.9	1.3	1.4	-0.3	0.4	-0.3
Illnesses of father: Heart disease	0.9	1.3	4.7	-0.9	1.6	1.3	1.3	2.2	-0.4	0.0	0.3	-1.2	-0.3	-0.7	-1.4
Illnesses of siblings: Diabetes	2.0	2.5	5.5	1.0	0.6	-1.0	-0.7	1.6	1.3	1.4	2.4	1.4	1.9	2.1	2.3
Smoking status: Previous	0.6	0.9	3.8	1.6	0.5	-0.7	-0.4	-1.2	-0.3	0.3	-0.5	-0.1	1.0	1.9	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.9	-1.4	-0.4	0.8	0.3	-0.1	-1.0	-0.2	-0.7	-1.3	-0.0	-1.7	-0.9
Whole body fat-free mass	0.9	5.2	14.1	0.2	-2.0	-3.6	-1.6	3.1	3.2	1.4	0.6	3.8	2.0	-1.0	1.2
Leg fat-free mass (right)	0.9	4.7	12.1	0.5	-2.1	-3.4	-1.3	3.1	3.0	1.2	0.0	3.5	1.7	-1.2	1.1
Arm fat percentage (left)	1.4	5.6	22.5	2.5	0.3	-2.3	-1.8	4.7	2.4	1.9	2.2	2.1	2.0	2.0	2.0
Average weekly red wine intake	0.5	0.7	5.0	-0.1	-0.6	0.4	0.2	2.2	0.6	-0.0	0.4	0.7	0.1	1.2	0.3
Handedness (chirality/laterality): Left-handed	1.1	1.3	4.5	2.1	-0.3	0.3	0.8	-0.6	-0.1	1.2	-0.6	0.6	1.9	1.0	1.8
Mood swings	2.1	3.8	14.3	0.9	2.1	-1.7	-0.3	1.5	3.6	2.6	0.6	3.8	0.1	-0.3	0.3
Loneliness, isolation	0.7	0.9	4.7	0.3	1.6	-0.2	-0.2	2.2	0.8	0.9	0.3	0.7	1.0	0.7	0.2
Long-standing illness, disability or infirmity	1.1	1.6	3.2	1.3	0.6	-1.5	-1.0	1.6	0.8	1.2	1.4	1.8	1.1	1.1	1.5
Ever had bowel cancer screening	1.1	1.3	2.9	-0.7	-1.6	1.2	1.7	1.5	-0.9	-1.4	-0.5	-0.6	-0.8	-0.8	-1.0
Diabetes diagnosed by doctor	1.0	1.6	4.9	1.0	0.8	-1.1	-0.5	2.2	1.8	1.0	-0.7	2.2	-0.2	0.7	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.2	-1.5	-0.3	-0.6	0.3	0.9	0.8	0.5	-0.2	0.8	0.1	-1.0	0.0
Friendships satisfaction	2.3	2.9	8.1	2.8	1.5	-1.0	-0.2	1.7	1.1	1.9	-0.1	1.4	1.8	2.3	2.2
Qualifications: nursing, teaching	0.3	0.5	2.8	0.3	0.3	0.8	1.7	0.8	0.4	0.1	0.3	-0.7	0.1	0.4	-0.1
Commuting to job workplace: Walk	0.8	0.9	2.4	-0.9	0.6	-1.5	0.2	-1.3	0.8	0.3	1.5	0.8	-1.0	-0.3	-0.6
Eye problems/disorders: Cataract	0.5	0.6	2.8	1.1	1.7	1.1	0.2	0.3	-0.9	0.3	0.1	-0.9	0.1	-0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	6.1	-2.5	-1.7	-0.9	-1.7	-1.6	-1.3	-2.1	0.5	-1.3	-0.7	-0.6	-1.0
Medication for cholesterol	0.5	0.7	2.1	0.6	-0.8	-0.9	-1.4	-1.5	-1.0	-0.2	0.9	0.4	0.1	0.6	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.5	1.6	0.0	-1.0	-0.5	0.8	1.3	0.9	-0.1	1.3	1.0	1.1	1.5
Back pain experienced in last month	0.1	0.2	0.5	-0.0	0.3	-0.7	0.1	-0.5	0.6	0.5	-0.1	0.7	0.2	-0.0	0.2
Mineral and other dietary supplements	0.3	0.4	1.9	0.6	0.4	-0.3	-0.9	1.4	-0.0	-0.0	0.2	-0.5	0.9	0.3	-0.1
Breast cancer (self-reported)	0.3	0.4	1.2	-1.1	-0.8	0.2	1.0	-0.4	-0.7	-0.7	-0.2	0.1	0.2	-0.5	0.0
Asthma (self-reported)	0.3	0.6	2.2	0.3	-0.7	-1.2	-0.5	-1.3	-0.3	-0.7	-0.6	0.1	-0.3	-1.5	0.2
Osteoporosis (self-reported)	0.2	0.3	1.1	-0.7	1.1	0.1	0.0	-0.4	0.9	0.3	0.1	0.2	-0.3	-0.6	-0.3
Osteoarthritis (self-reported)	1.4	1.8	6.5	-1.2	-0.3	-2.3	-0.9	-1.2	1.9	1.0	-0.3	2.6	-0.2	-0.7	0.4
Medication: Aspirin	1.3	1.7	6.7	-1.6	-2.3	-0.2	0.1	-0.2	-1.6	-2.6	0.2	-1.1	-0.9	-0.1	-1.3
Medication: Gliclazide	1.0	1.1	3.7	0.4	1.2	0.9	1.4	1.9	1.2	0.6	-1.5	0.9	0.1	0.4	0.1
Illnesses of father: None of the above (group 1)	2.1	2.5	6.7	2.6	-0.0	0.1	0.5	0.6	1.3	1.8	-0.3	2.2	1.8	2.2	2.1
Smoking status: Current	1.4	2.2	6.7	0.7	-1.5	-2.6	-1.4	-1.4	1.8	-1.9	-0.9	1.2	-1.3	-1.5	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	10.4	-1.4	0.6	1.4	0.3	3.2	-2.2	0.7	2.6	-0.6	0.8	0.3	-0.5
Whole body water mass	0.9	5.1	14.0	0.2	-2.1	-3.6	-1.6	3.1	3.2	1.4	0.5	3.7	1.9	-1.1	1.1
Leg predicted mass (right)	0.9	4.6	12.1	0.4	-2.2	-3.4	-1.3	3.1	3.0	1.2	-0.1	3.5	1.6	-1.4	1.1
Arm fat mass (left)	1.7	7.0	24.5	2.4	-0.4	-2.7	-1.5	5.0	2.9	2.4	2.0	3.0	2.7	1.7	2.4
Number of self-reported non-cancer illnesses	0.2	0.3	1.5	-0.5	0.2	-0.3	0.5	-0.7	1.2	-0.1	-0.1	1.0	-0.5	-0.1	-0.3
Average weekly champagne plus white wine intake	1.5	2.0	5.3	-1.1	-1.7	2.3	1.7	-0.9	-1.3	-0.9	-0.8	-2.3	-1.2	-0.5	-1.2
Miserableness	3.1	5.3	14.7	2.1	3.2	-1.1	-0.6	2.4	2.6	3.8	0.8	2.9	1.8	1.5	2.4
Guilty feelings	2.4	3.7	9.8	1.6	2.1	-1.7	-1.7	2.1	2.5	3.1	0.4	2.9	1.1	0.6	1.0
Wears glasses or contact lenses	0.5	0.6	1.9	-0.9	-0.7	0.1	0.4	0.9	-1.3	-0.8	-0.4	-1.4	0.0	-0.6	-0.5
Ever taken oral contraceptive pill	1.0	1.1	4.0	-0.2	-0.5	-2.0	-1.9	-0.9	-0.1	-0.2	1.7	0.1	-0.5	1.1	0.2
Hearing aid user	1.9	2.1	5.7	-2.2	-2.4	1.2	1.4	-1.1	-1.2	-1.3	-1.1	-0.1	-0.5	-2.1	-1.0
Mother’s age at death	1.4	1.8	3.9	2.0	1.1	1.6	0.9	1.6	-1.8	-0.6	-2.0	-1.5	-0.2	0.1	-1.0
Financial situation satisfaction	0.3	0.3	1.0	1.0	-0.2	-0.9	0.1	0.2	1.0	0.3	0.2	0.5	-0.1	0.7	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.1	0.1	-1.0	-1.5	-0.3	-0.8	0.8	0.2	0.9	1.1	-0.5	-0.5	-0.2
Commuting to job workplace: Public transport	1.0	1.2	3.0	1.6	0.6	-1.3	-1.2	0.6	1.6	0.8	-0.2	1.4	0.1	1.7	0.6
Eye problems/disorders: Glaucoma	0.8	0.9	3.3	1.2	0.0	-1.4	-1.8	-1.6	-0.5	0.1	-0.4	-0.3	-1.0	0.0	0.1
Medication: Blood pressure	0.3	0.6	2.1	1.5	0.2	0.1	0.5	0.8	1.3	-0.1	-0.6	0.7	0.9	0.7	0.4
Pain type(s) experienced in last month: Hip pain	1.6	2.0	5.0	1.6	0.5	-1.9	-1.3	0.3	0.4	1.4	0.5	2.0	0.5	2.2	1.9
Supplements: Fish oil (including cod liver oil)	0.4	0.6	3.5	0.5	-0.3	0.1	0.9	-1.9	0.5	0.2	-1.0	0.4	-0.7	-0.1	0.3
High cholesterol (Self-reported)	0.5	1.0	3.8	-2.0	0.0	1.4	0.9	0.2	0.0	-1.5	-0.5	-1.0	-0.9	-0.0	-0.7
Medication: Bendroflumethiazide	0.3	0.4	1.4	0.5	-0.2	-0.9	0.3	0.4	0.8	-0.4	-0.0	-0.4	0.8	1.2	0.8
Medication: Paracetamol	0.4	0.7	2.7	-0.9	0.0	-0.4	-0.4	-1.6	1.2	0.7	0.4	1.3	0.1	0.3	0.4
Medication: Lisinopril	0.2	0.3	1.1	-0.4	-0.1	-0.9	-0.0	-1.0	0.8	-0.8	0.6	0.1	0.2	-0.0	0.2
Medication: Atorvastatin	0.9	1.2	4.1	-1.3	-0.7	1.2	1.1	-0.7	-0.2	-2.0	-0.9	-0.5	-0.9	-1.6	-0.4
Illnesses of father: High blood pressure	1.2	1.5	6.2	-1.5	-0.5	-1.0	-0.8	-0.4	-0.1	-1.7	2.5	-1.5	-0.7	0.7	-1.4
Alcohol drinker status: Never	1.4	1.7	6.8	-0.5	-1.1	-0.8	0.1	-1.0	-0.9	-0.8	0.5	-2.2	-2.6	-1.4	-1.4
Ever smoked	0.8	1.4	5.7	1.3	-0.7	-2.4	-2.1	-0.9	0.3	-1.5	0.0	-0.0	0.1	1.1	0.6
Basal metabolic rate	1.1	5.8	15.1	0.7	-1.5	-3.5	-1.5	3.7	3.3	1.8	0.7	3.9	2.4	-0.5	1.5
Leg fat percentage (left)	2.1	7.5	22.4	2.9	1.3	-1.7	-1.0	4.7	2.4	2.7	2.7	2.4	3.0	3.4	2.9
Arm fat-free mass (left)	1.0	5.0	13.6	0.9	-1.3	-2.8	-1.0	3.2	3.1	2.1	0.8	3.7	2.8	-0.3	1.9
Number of operations (self-reported)	0.2	0.4	1.1	-0.8	-0.4	0.2	0.7	1.1	0.2	-0.8	0.5	-0.0	-0.5	-0.3	-0.6
Average weekly beer plus cider intake	0.2	0.3	1.1	0.4	-0.1	-0.6	-0.3	-1.0	-0.7	0.6	0.1	-0.1	0.6	0.2	0.5
Irritability	0.5	0.9	4.2	1.1	0.7	-0.4	-0.1	0.9	2.0	1.1	-0.7	0.9	0.6	0.5	0.7
Risk taking	0.3	0.5	2.0	-0.5	0.0	-0.7	-0.5	-1.4	0.8	-1.0	-0.1	0.3	-0.5	-0.8	-0.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.3	0.1	-0.8	0.1	0.5	-0.5	-1.1	-0.8	-0.2	-0.8	-0.2	0.1	0.0
Fractured/broken bones in last 5 years	2.1	2.7	6.3	2.1	1.5	-0.3	-0.2	0.7	2.3	2.1	0.2	2.0	2.0	1.1	2.5
Age started oral contraceptive pill	0.5	0.6	1.7	-1.1	-0.4	1.3	0.9	0.1	-0.7	-0.9	-0.6	-0.6	-0.3	-0.1	-1.0
Diastolic blood pressure, automated reading	0.8	2.6	7.7	1.1	0.7	-2.5	-2.1	-1.8	1.4	1.0	2.8	1.1	0.9	1.5	1.0
Ever depressed for a whole week	0.2	0.2	0.7	-0.5	-0.3	-0.9	-0.1	-0.1	-0.3	0.1	0.3	0.6	0.6	0.4	0.6
Unable to work because of sickness or disability	1.3	1.7	4.9	-2.2	-0.1	-1.2	-0.4	-1.9	0.2	-0.5	0.4	0.5	-1.8	-2.2	-1.6
Commuting to job workplace: Cycle	0.4	0.5	2.2	-0.6	-0.0	-0.7	-0.4	-0.8	1.5	-0.1	0.7	0.8	-0.3	-0.4	-0.9
Myopia	0.7	1.0	4.9	-0.4	-0.0	-1.3	-2.2	1.2	0.4	0.4	-0.1	1.2	1.1	-0.3	0.5
Vascular/heart problems diagnosed by doctor	0.1	0.2	1.3	-0.2	-0.0	-0.0	-0.5	1.1	-0.3	0.6	-0.1	-0.1	-0.4	-0.4	0.1
Cholesterol lowering medication	0.7	1.1	5.1	0.0	0.2	0.3	0.0	2.3	1.9	0.4	0.7	0.6	0.6	1.6	0.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.2	-0.1	0.1	-2.0	-1.8	2.0	0.2	0.7	0.4	1.5	0.6	0.7	1.1
Pain experienced in last month	0.6	1.0	3.1	-0.7	-0.9	0.2	-0.7	-0.5	-0.8	-1.6	-0.4	-0.8	-1.1	-1.8	-1.1
Supplements: Calcium	1.1	1.2	3.7	-1.2	0.2	1.1	0.6	-0.7	-1.0	-0.4	-1.0	-1.1	-1.2	-1.9	-1.5
Basal cell carcinoma (self-reported)	1.3	1.6	3.6	-1.1	-1.4	0.8	0.8	-1.4	-0.8	-1.3	-0.9	-0.9	-1.8	-1.9	-1.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.4	0.5	0.3	0.8	1.2	-0.1	0.9	1.1	-0.2	1.0	0.1	-0.2	0.8
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	5.4	2.0	0.3	1.4	1.1	-0.3	0.4	0.7	-2.3	0.4	0.8	0.1	1.4
Heart disease (siblings)	0.8	0.9	3.7	0.5	-1.4	-0.2	0.8	0.1	1.6	0.5	0.4	1.9	0.5	0.7	0.9
Alcohol drinker status: Previous	1.0	1.2	4.5	1.4	-0.7	2.1	0.8	1.5	0.1	0.5	-1.2	1.1	0.5	0.0	0.6
Pack years of smoking	1.1	1.7	4.2	-1.1	-1.2	-1.7	-1.7	-0.4	-0.7	-1.7	-0.7	-0.8	-1.2	-2.1	-1.0
Impedance of whole body	1.4	7.3	21.9	-1.1	3.4	4.7	2.6	-1.9	-3.4	-1.1	-1.2	-4.2	-2.5	-0.3	-2.1
Leg fat mass (left)	2.3	9.0	26.6	2.8	0.5	-2.7	-1.7	5.2	3.0	2.9	2.5	3.4	3.5	2.6	3.1
Arm predicted mass (left)	1.0	5.1	15.2	0.9	-1.3	-2.9	-1.1	2.9	3.2	2.1	0.8	3.9	2.7	-0.2	1.8