TWAS hub - SFXN3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1610	0.0450	2.0e-05	0.039	0.045	0.065	0.103	0.068	1.6e-05	3.5e-06	2.1e-08	1.5e-12	1.2e-08
2	GTEx	Brain Cortex	0.3150	0.1010	4.6e-03	0.029	NA	0.126	NA	0.086	5.3e-02	NA	2.5e-04	NA	2.2e-03
3	GTEx	Nerve Tibial	0.2361	0.0691	4.1e-04	0.066	NA	0.143	NA	0.168	2.0e-05	NA	2.6e-10	NA	5.7e-12
4	GTEx	Skin Sun Exposed Lower leg	0.1740	0.0610	1.4e-03	0.005	NA	0.005	NA	0.007	1.1e-01	NA	1.2e-01	NA	7.7e-02
5	METSIM	Adipose	0.1176	0.0335	8.2e-06	0.002	0.039	0.023	NA	0.012	1.2e-01	1.6e-06	1.7e-04	NA	6.0e-03
6	NTR	Blood	0.0289	0.0111	1.1e-03	0.023	0.007	0.021	0.014	0.024	4.2e-08	1.7e-03	1.8e-07	1.6e-05	2.7e-08
7	ROSMAP	Brain Pre-frontal Cortex	0.0959	0.0373	2.9e-03	0.000	0.019	0.042	0.042	0.006	3.3e-01	1.3e-03	3.2e-06	4.0e-06	5.1e-02
8	TCGA	Cervical Squamous Cell Carcinoma	0.1050	0.0510	6.2e-03	0.037	0.047	0.012	NA	0.013	6.6e-03	2.2e-03	8.2e-02	NA	7.0e-02
9	TCGA	Colon Adenocarcinoma	0.0700	0.0360	9.2e-03	0.033	0.038	0.053	NA	0.062	5.2e-03	2.9e-03	5.4e-04	NA	1.8e-04
10	TCGA	Brain Lower Grade Glioma	0.1786	0.0695	5.0e-03	0.049	0.042	0.049	NA	0.046	2.6e-06	1.4e-05	2.8e-06	NA	5.4e-06
11	TCGA	Lung Squamous Cell Carcinoma	0.0749	0.0323	1.6e-03	0.040	0.042	0.034	NA	0.039	2.1e-05	1.4e-05	8.6e-05	NA	2.6e-05
12	TCGA	Thyroid Carcinoma	0.1480	0.0470	2.5e-05	0.073	0.065	0.059	NA	0.071	1.2e-07	6.7e-07	1.9e-06	NA	2.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Commuting to job workplace: Car/motor vehicle	3.2	3.7	9.1	-1.6	-0.7	3.0	3.0	0.6	-2.2	-1.7	-1.1	-2.4	-1.1	-2.0	-1.7
Miserableness	3.1	5.3	14.7	2.1	3.2	-1.1	-0.6	2.4	2.6	3.8	0.8	2.9	1.8	1.5	2.4
Leg fat mass (right)	2.7	10.3	29.4	3.0	0.7	-2.9	-1.8	5.4	3.1	3.0	2.8	3.5	3.7	2.9	3.4
Body Mass Index (BMI) (2010)	2.4	3.3	18.1	0.3	-0.0	-1.8	-2.0	4.3	1.0	0.7	1.8	1.8	1.0	2.2	0.4
Neuroticism (2016)	2.4	3.5	10.9	1.2	3.3	-0.2	0.9	2.3	2.2	2.6	1.1	2.5	0.8	1.6	1.2
Chronic bronchitis/emphysema (father)	2.4	2.8	10.1	-1.5	1.8	1.5	1.9	-0.5	1.1	0.7	-2.7	1.1	-0.7	-3.2	-1.0
Body mass index (BMI)	2.4	10.2	22.3	3.0	-0.7	-3.6	-2.1	4.7	3.6	2.9	2.6	4.0	3.6	2.6	3.3
Leg fat percentage (right)	2.4	8.8	26.5	3.0	1.7	-1.8	-1.2	5.2	2.5	2.8	3.1	2.6	3.0	3.7	2.9
Guilty feelings	2.4	3.7	9.8	1.6	2.1	-1.7	-1.7	2.1	2.5	3.1	0.4	2.9	1.1	0.6	1.0
Maternal smoking around birth	2.3	3.3	11.2	-1.7	-1.3	1.2	0.7	-2.1	0.2	-2.1	-3.3	-0.2	-0.8	-3.4	-1.0
Friendships satisfaction	2.3	2.9	8.1	2.8	1.5	-1.0	-0.2	1.7	1.1	1.9	-0.1	1.4	1.8	2.3	2.2
Leg fat mass (left)	2.3	9.0	26.6	2.8	0.5	-2.7	-1.7	5.2	3.0	2.9	2.5	3.4	3.5	2.6	3.1
Depressed Affect (Nagel 2018)	2.2	4.7	17.4	1.2	2.2	-1.4	-0.2	2.0	3.4	3.3	0.8	4.2	1.1	0.8	1.4
Hip circumference	2.1	9.0	36.2	2.9	-0.2	-2.0	-0.4	6.0	2.9	2.9	2.3	3.4	3.6	2.3	2.8
Mood swings	2.1	3.8	14.3	0.9	2.1	-1.7	-0.3	1.5	3.6	2.6	0.6	3.8	0.1	-0.3	0.3
Illnesses of father: None of the above (group 1)	2.1	2.5	6.7	2.6	-0.0	0.1	0.5	0.6	1.3	1.8	-0.3	2.2	1.8	2.2	2.1
Leg fat percentage (left)	2.1	7.5	22.4	2.9	1.3	-1.7	-1.0	4.7	2.4	2.7	2.7	2.4	3.0	3.4	2.9
Fractured/broken bones in last 5 years	2.1	2.7	6.3	2.1	1.5	-0.3	-0.2	0.7	2.3	2.1	0.2	2.0	2.0	1.1	2.5
Alzheimer’s Disease (in mother)	2.0	2.4	7.5	0.9	-1.1	-2.7	-2.7	-0.1	-0.0	-0.9	2.1	0.2	0.4	2.2	1.0
Fed-up feelings	2.0	3.7	9.3	1.8	2.5	-0.7	0.1	2.2	2.7	3.0	-0.2	2.4	1.8	1.5	1.3
Exposure to tobacco smoke outside home	2.0	2.6	8.5	-1.0	0.1	2.4	2.5	-0.7	-1.2	-0.8	-2.9	0.0	-1.0	-2.3	-0.8
Illnesses of siblings: Diabetes	2.0	2.5	5.5	1.0	0.6	-1.0	-0.7	1.6	1.3	1.4	2.4	1.4	1.9	2.1	2.3
Hearing aid user	1.9	2.1	5.7	-2.2	-2.4	1.2	1.4	-1.1	-1.2	-1.3	-1.1	-0.1	-0.5	-2.1	-1.0
Arm fat mass (right)	1.8	7.5	26.1	2.6	-0.3	-2.9	-1.8	5.1	2.8	2.4	2.2	3.0	2.9	1.9	2.6
Whole body fat mass	1.8	7.3	28.7	2.6	0.5	-2.4	-1.4	5.4	2.5	2.5	2.1	2.7	3.0	2.2	2.6
BMI	1.7	9.7	34.9	3.1	-0.3	-2.8	-1.5	5.9	2.9	2.8	2.6	3.5	3.5	2.7	2.6
Waist circumference	1.7	6.1	15.6	2.2	0.3	-2.2	-1.2	4.0	2.9	2.3	1.8	3.3	3.0	1.9	2.5
Falls in the last year	1.7	2.4	8.1	-0.2	0.6	-2.5	-1.2	0.8	2.2	1.4	1.0	2.9	0.5	1.2	1.4
Medication: Ibuprofen	1.7	2.0	5.6	-1.3	1.7	-2.4	-0.9	-0.5	2.2	0.7	1.3	2.3	-0.5	-0.1	-0.5
Arm fat mass (left)	1.7	7.0	24.5	2.4	-0.4	-2.7	-1.5	5.0	2.9	2.4	2.0	3.0	2.7	1.7	2.4
Allergy or Eczema	1.6	4.2	9.3	1.8	-0.1	-1.0	-0.6	0.1	2.8	3.1	2.0	2.9	1.6	2.5	2.8
Medication for hormone replacement therapy	1.6	1.7	6.7	-1.8	-0.2	0.6	0.8	-1.2	0.0	-0.2	0.2	-0.3	-2.2	-2.6	-1.8
Hearing difficulty/problems with background noise	1.6	2.5	7.0	-1.6	-0.1	2.6	2.7	2.4	-0.3	-0.4	-1.8	-0.2	0.5	-1.7	-1.2
Weight	1.6	8.0	28.5	1.9	-0.5	-2.9	-1.1	5.3	3.6	2.7	1.5	3.9	3.1	1.0	2.3
Arm fat percentage (right)	1.6	6.2	24.3	2.8	0.2	-2.3	-1.8	4.9	2.3	1.9	2.0	2.1	2.4	2.2	2.4
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	10.3	-0.4	0.6	-3.2	-1.7	1.8	1.9	0.5	1.0	2.6	0.3	0.9	1.1
Body fat percentage	1.6	6.4	22.8	2.7	1.3	-1.6	-1.1	4.8	2.3	2.5	2.1	2.2	2.6	2.7	2.6
Had major operations	1.6	1.8	4.8	-1.1	-0.5	1.5	0.8	1.0	-1.8	-2.2	-1.7	-1.1	-1.0	-0.7	-1.8
Pain type(s) experienced in last month: Hip pain	1.6	2.0	5.0	1.6	0.5	-1.9	-1.3	0.3	0.4	1.4	0.5	2.0	0.5	2.2	1.9
Alzheimer’s Disease (including proxy)	1.5	2.2	7.2	1.4	-0.1	-2.0	-2.7	0.1	-1.0	-1.4	2.2	-0.2	0.1	2.2	0.9
Systolic Blood Pressure	1.5	7.3	63.4	0.2	1.7	1.7	0.2	-8.0	-0.2	-1.0	-2.3	-1.4	-1.9	-2.0	-1.6
Diabetes (father)	1.5	1.8	6.9	-0.6	-1.6	-2.2	-1.9	-2.6	0.5	-0.7	0.3	-0.8	-0.9	-0.7	-0.9
Hayfever, allergic rhinitis or eczema	1.5	3.3	7.2	2.3	-0.9	-1.1	-0.9	-0.4	2.3	2.4	0.5	2.4	1.5	2.1	2.7
Nervous feelings	1.5	2.9	13.2	0.2	3.6	2.2	2.3	1.7	1.5	1.6	-0.8	0.8	-0.6	-0.2	-1.3
Number of live births	1.5	2.2	4.3	0.1	-0.7	-0.2	-0.5	2.0	2.1	1.7	1.3	1.6	2.1	1.2	1.9
Happiness	1.5	1.9	5.1	2.2	1.1	-0.8	-0.1	1.8	1.2	1.7	0.6	1.0	0.7	2.1	1.4
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	7.5	-0.9	2.0	-2.0	-0.3	-0.1	2.3	0.9	0.8	2.7	0.1	0.0	-0.1
Medication: Cholesterol lowering	1.5	2.3	6.7	-2.6	-0.8	1.5	1.8	-1.0	-0.8	-1.6	-0.7	-1.4	-1.8	-1.3	-1.8
Average weekly champagne plus white wine intake	1.5	2.0	5.3	-1.1	-1.7	2.3	1.7	-0.9	-1.3	-0.9	-0.8	-2.3	-1.2	-0.5	-1.2
Neuroticism (Nagel 2018)	1.4	3.2	9.7	0.9	2.4	-0.8	0.2	1.7	3.1	3.0	0.2	3.1	0.1	0.4	0.3
Alzheimer’s Disease (in father)	1.4	1.6	6.6	-0.7	-1.1	0.1	-0.5	-0.5	-2.1	-2.6	0.8	-1.7	-1.0	-0.8	-0.7
Primary Biliary Cirrhosis	1.4	2.0	4.8	2.1	-0.1	-0.0	-0.9	1.7	-1.3	1.5	1.1	-1.1	1.5	2.2	1.3
Type 2 Diabetes (T2D) (2018)	1.4	2.7	6.0	2.4	1.3	-0.7	-0.7	2.4	0.9	1.6	-0.7	1.9	1.2	1.7	2.4
Depression (self-reported)	1.4	1.7	4.2	0.2	1.8	0.5	1.8	0.4	1.9	1.3	-1.6	2.0	0.5	-0.7	0.2
Impedance of arm (left)	1.4	6.5	15.8	-1.4	2.2	3.8	2.1	-1.1	-3.0	-1.7	-1.7	-4.0	-3.3	-1.4	-2.8
Migraine (self-reported)	1.4	1.7	6.4	-1.1	-1.1	2.1	2.5	-0.9	-0.4	-0.1	-0.2	-1.8	-1.1	-0.1	-1.3
Leg pain on walking	1.4	1.8	7.8	-0.0	0.6	-0.6	0.4	0.4	2.4	1.8	-0.2	2.8	1.4	0.5	1.2
Arm fat percentage (left)	1.4	5.6	22.5	2.5	0.3	-2.3	-1.8	4.7	2.4	1.9	2.2	2.1	2.0	2.0	2.0
Osteoarthritis (self-reported)	1.4	1.8	6.5	-1.2	-0.3	-2.3	-0.9	-1.2	1.9	1.0	-0.3	2.6	-0.2	-0.7	0.4
Smoking status: Current	1.4	2.2	6.7	0.7	-1.5	-2.6	-1.4	-1.4	1.8	-1.9	-0.9	1.2	-1.3	-1.5	-0.0
Mother’s age at death	1.4	1.8	3.9	2.0	1.1	1.6	0.9	1.6	-1.8	-0.6	-2.0	-1.5	-0.2	0.1	-1.0
Alcohol drinker status: Never	1.4	1.7	6.8	-0.5	-1.1	-0.8	0.1	-1.0	-0.9	-0.8	0.5	-2.2	-2.6	-1.4	-1.4
Impedance of whole body	1.4	7.3	21.9	-1.1	3.4	4.7	2.6	-1.9	-3.4	-1.1	-1.2	-4.2	-2.5	-0.3	-2.1
Crohns Disease (2017)	1.3	2.9	7.3	-1.0	-1.9	2.3	0.7	-1.6	-1.6	-2.7	-2.2	-1.3	-0.5	-2.0	-1.0
Smoking Status	1.3	3.2	10.1	2.1	-0.9	-3.1	-2.5	-3.2	0.4	-2.0	-1.2	0.9	-0.8	-0.5	0.6
Neuroticism	1.3	3.1	9.4	0.8	2.8	0.1	0.3	1.7	2.8	3.1	-0.3	2.8	0.3	0.6	0.2
Hand grip strength (left)	1.3	3.5	9.7	0.9	-1.9	3.1	1.4	-0.2	-2.3	-2.5	-2.8	-1.8	0.6	-1.7	-0.7
Trunk fat mass	1.3	5.6	25.3	2.1	0.4	-2.1	-1.1	5.0	2.4	2.2	1.7	2.4	2.3	1.6	2.0
Impedance of arm (right)	1.3	5.8	16.0	-0.8	2.4	3.6	1.8	-0.9	-3.2	-1.8	-2.1	-4.0	-2.6	-1.1	-2.1
Worry too long after embarrassment	1.3	2.2	6.9	0.1	1.4	-1.7	-0.4	2.6	2.2	2.2	-0.2	2.0	-0.8	0.1	-0.5
Medication: Seretide 50 evohaler	1.3	1.5	4.0	-0.2	-1.2	0.5	0.3	-1.3	-1.0	-1.0	-1.7	-1.2	-1.5	-2.0	-1.3
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	6.1	-2.5	-1.7	-0.9	-1.7	-1.6	-1.3	-2.1	0.5	-1.3	-0.7	-0.6	-1.0
Medication: Aspirin	1.3	1.7	6.7	-1.6	-2.3	-0.2	0.1	-0.2	-1.6	-2.6	0.2	-1.1	-0.9	-0.1	-1.3
Unable to work because of sickness or disability	1.3	1.7	4.9	-2.2	-0.1	-1.2	-0.4	-1.9	0.2	-0.5	0.4	0.5	-1.8	-2.2	-1.6
Basal cell carcinoma (self-reported)	1.3	1.6	3.6	-1.1	-1.4	0.8	0.8	-1.4	-0.8	-1.3	-0.9	-0.9	-1.8	-1.9	-1.4
Depression (Nagel 2018)	1.2	1.8	7.0	0.8	0.1	-1.0	0.6	1.2	2.2	0.8	1.4	2.6	0.7	1.6	1.1
Hearing difficulty/problems: Yes	1.2	1.9	7.1	-1.7	-1.7	0.6	1.0	-0.7	-1.1	-1.5	-1.2	-0.9	-0.4	-2.7	-1.4
Pack years adult smoking proportion	1.2	1.8	5.7	-1.1	-0.6	-1.9	-1.8	-0.8	-0.5	-1.4	-0.8	-0.7	-1.4	-2.4	-1.1
Trunk fat percentage	1.2	4.6	20.0	2.4	1.2	-1.3	-0.7	4.5	1.9	2.2	1.6	1.7	2.0	2.1	2.0
Current tobacco smoking	1.2	1.9	5.4	0.3	-1.5	-2.3	-1.0	-1.4	1.6	-2.0	-0.9	1.1	-1.3	-1.6	-0.2
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.3	-1.4	0.2	1.4	1.8	0.7	-0.9	-1.1	0.3	-0.9	-0.7	-1.5	-1.8
Impedance of leg (left)	1.2	5.8	20.0	-0.5	4.2	4.5	2.4	-1.8	-2.8	-0.2	-0.3	-3.4	-1.2	0.8	-1.0
Diabetes (self-reported)	1.2	1.8	4.2	1.4	1.0	-1.3	-1.3	2.0	1.8	1.3	-0.6	1.9	0.2	1.2	1.3
Mouth/teeth dental problems: Dentures	1.2	2.0	12.5	1.2	1.3	-0.1	-0.3	-3.5	1.8	0.7	-0.8	0.1	-2.1	0.3	-0.4
Family relationship satisfaction	1.2	1.5	4.3	1.6	0.9	0.1	1.0	2.1	0.7	1.5	-0.4	0.9	1.5	1.0	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.7	-0.8	0.7	1.0	1.8	0.1	-0.6	-1.3	-1.9	-0.9	-0.7	-1.7	-1.4
Illnesses of father: High blood pressure	1.2	1.5	6.2	-1.5	-0.5	-1.0	-0.8	-0.4	-0.1	-1.7	2.5	-1.5	-0.7	0.7	-1.4
Crohns Disease (2012)	1.1	1.8	6.8	-0.5	-0.3	2.6	1.3	0.1	-0.4	-1.7	-2.1	-1.0	-0.5	-1.7	-1.2
LDL Cholesterol	1.1	1.7	5.9	0.4	0.8	-1.3	-1.0	0.7	1.2	1.3	0.2	1.4	2.4	1.3	2.1
Medication: Co-codamol	1.1	1.3	7.0	-0.2	0.2	-0.8	-0.3	0.2	1.8	1.4	0.4	2.6	0.9	0.3	1.3
Leg fat-free mass (left)	1.1	5.7	14.9	0.7	-1.6	-3.6	-1.7	3.6	3.4	1.6	0.4	3.9	2.0	-0.9	1.4
Relative age voice broke	1.1	1.7	7.5	0.6	1.0	-0.2	-2.1	-0.3	0.3	1.0	1.4	0.2	1.2	2.7	1.6
Neuroticism score	1.1	2.4	7.3	1.1	2.7	-0.4	-0.1	2.1	2.3	2.2	-0.0	2.2	-0.0	0.4	-0.0
Alcohol intake versus 10 years previously	1.1	1.7	6.6	2.6	0.1	-1.4	-1.0	-0.9	0.8	1.5	0.1	2.0	1.2	0.0	1.4
Ever highly irritable/argumentative for 2 days	1.1	1.3	6.2	-0.8	1.0	-1.0	-0.5	0.9	2.5	0.4	1.1	1.8	-0.0	0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	4.3	-1.0	0.8	0.3	0.9	-1.5	1.1	-0.0	-1.1	0.4	-1.6	-1.9	-2.1
Number of children fathered	1.1	1.2	3.1	0.3	-1.5	-1.8	-0.9	1.4	-0.0	-1.7	1.4	-0.4	-1.1	0.4	-0.7
Shortness of breath walking on level ground	1.1	1.3	5.8	0.9	-0.2	0.1	1.0	0.4	2.4	1.0	-0.5	1.7	1.2	0.5	1.5
Emphysema/chronic bronchitis	1.1	1.3	4.6	-1.1	-0.2	-1.1	-1.1	-1.0	0.1	-1.1	-0.3	0.1	-1.6	-2.1	-1.4
Handedness (chirality/laterality): Left-handed	1.1	1.3	4.5	2.1	-0.3	0.3	0.8	-0.6	-0.1	1.2	-0.6	0.6	1.9	1.0	1.8
Long-standing illness, disability or infirmity	1.1	1.6	3.2	1.3	0.6	-1.5	-1.0	1.6	0.8	1.2	1.4	1.8	1.1	1.1	1.5
Ever had bowel cancer screening	1.1	1.3	2.9	-0.7	-1.6	1.2	1.7	1.5	-0.9	-1.4	-0.5	-0.6	-0.8	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	10.4	-1.4	0.6	1.4	0.3	3.2	-2.2	0.7	2.6	-0.6	0.8	0.3	-0.5
Basal metabolic rate	1.1	5.8	15.1	0.7	-1.5	-3.5	-1.5	3.7	3.3	1.8	0.7	3.9	2.4	-0.5	1.5
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.2	-0.1	0.1	-2.0	-1.8	2.0	0.2	0.7	0.4	1.5	0.6	0.7	1.1
Supplements: Calcium	1.1	1.2	3.7	-1.2	0.2	1.1	0.6	-0.7	-1.0	-0.4	-1.0	-1.1	-1.2	-1.9	-1.5
Pack years of smoking	1.1	1.7	4.2	-1.1	-1.2	-1.7	-1.7	-0.4	-0.7	-1.7	-0.7	-0.8	-1.2	-2.1	-1.0
Type 2 Diabetes (T2D) (2012)	1.0	1.1	7.1	-0.9	0.1	0.8	0.2	0.1	0.4	0.7	-2.7	0.5	-0.6	-1.7	-0.7
Supplements: Zinc	1.0	1.1	3.6	-1.2	-1.5	0.0	1.0	-0.6	0.3	0.0	-1.3	0.0	-1.7	-1.9	-0.3
Impedance of leg (right)	1.0	5.0	19.5	-0.5	4.4	4.0	1.8	-1.2	-2.6	-0.1	-0.1	-3.1	-1.3	0.8	-1.0
Leg predicted mass (left)	1.0	5.5	14.4	0.7	-1.7	-3.6	-1.7	3.6	3.3	1.6	0.4	3.8	1.9	-0.9	1.4
Blood clot in the leg (DVT)	1.0	1.3	4.8	2.1	0.5	1.2	1.1	0.3	0.5	0.9	-2.2	0.5	0.8	0.1	1.5
Comparative body size at age 10	1.0	2.8	11.8	-0.4	-1.4	-0.3	1.2	3.4	2.4	1.2	-0.2	3.1	1.0	0.2	0.6
Diabetes diagnosed by doctor	1.0	1.6	4.9	1.0	0.8	-1.1	-0.5	2.2	1.8	1.0	-0.7	2.2	-0.2	0.7	1.2
Medication: Gliclazide	1.0	1.1	3.7	0.4	1.2	0.9	1.4	1.9	1.2	0.6	-1.5	0.9	0.1	0.4	0.1
Ever taken oral contraceptive pill	1.0	1.1	4.0	-0.2	-0.5	-2.0	-1.9	-0.9	-0.1	-0.2	1.7	0.1	-0.5	1.1	0.2
Commuting to job workplace: Public transport	1.0	1.2	3.0	1.6	0.6	-1.3	-1.2	0.6	1.6	0.8	-0.2	1.4	0.1	1.7	0.6
Arm fat-free mass (left)	1.0	5.0	13.6	0.9	-1.3	-2.8	-1.0	3.2	3.1	2.1	0.8	3.7	2.8	-0.3	1.9
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	5.4	2.0	0.3	1.4	1.1	-0.3	0.4	0.7	-2.3	0.4	0.8	0.1	1.4
Alcohol drinker status: Previous	1.0	1.2	4.5	1.4	-0.7	2.1	0.8	1.5	0.1	0.5	-1.2	1.1	0.5	0.0	0.6
Arm predicted mass (left)	1.0	5.1	15.2	0.9	-1.3	-2.9	-1.1	2.9	3.2	2.1	0.8	3.9	2.7	-0.2	1.8
Ovarian Cancer	0.9	1.2	6.1	-1.0	1.0	-1.6	-2.5	-0.3	-0.7	-0.6	1.0	-0.4	-0.5	-0.5	-1.0
Age at First Birth	0.9	1.3	5.9	0.4	1.2	-1.3	-0.9	-0.7	0.7	0.1	2.4	-0.5	0.0	1.9	-0.3
HbA1C	0.9	1.1	2.5	-0.9	-0.5	0.5	0.5	-1.4	-1.0	-0.7	-0.8	-1.2	-1.6	-1.0	-1.4
Angina	0.9	1.1	2.6	-0.0	-1.1	1.2	1.3	-1.2	-0.2	-1.6	-1.3	0.3	-1.3	-1.3	-0.6
Townsend deprivation index at recruitment	0.9	1.2	4.2	0.7	0.7	-2.1	-1.4	-0.4	1.4	0.6	0.5	1.8	1.0	0.4	0.8
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.6	-0.2	-0.9	-1.9	-1.6	-1.4	-0.2	-1.1	0.6	-0.1	0.2	0.9	0.0
Hair/balding pattern: Pattern 2	0.9	1.1	3.1	1.4	0.4	-0.7	-1.8	-1.6	-1.6	-0.5	0.8	-1.0	0.2	0.9	0.5
Had other major operations	0.9	1.1	5.5	0.0	1.1	0.7	1.1	2.3	0.7	1.1	0.9	0.6	0.8	0.8	0.6
Medication: Lansoprazole	0.9	1.0	3.0	0.5	1.1	-1.2	-0.1	0.6	1.7	-0.1	1.0	1.0	-1.5	0.7	-0.9
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	5.9	0.0	0.2	0.2	0.9	0.3	-1.3	-0.5	0.7	-2.4	-1.5	-0.8	-2.2
Arm fat-free mass (right)	0.9	4.8	14.3	0.1	-1.8	-3.3	-1.4	2.5	3.2	1.7	1.2	3.8	2.1	-0.6	1.4
Age at first live birth	0.9	1.6	5.6	-2.4	-1.0	0.4	-0.1	-1.0	-1.2	-1.6	0.7	-1.5	-1.1	0.1	-2.0
Angina (self-reported)	0.9	1.2	3.1	-0.2	-1.2	1.0	1.2	-1.4	-0.2	-1.7	-1.1	0.4	-1.5	-1.3	-0.6
Medication: Omeprazole	0.9	1.1	2.8	0.3	-0.0	-1.7	-1.6	1.3	0.1	1.0	0.3	1.2	0.9	0.5	1.3
Arm predicted mass (right)	0.9	4.4	13.9	0.1	-1.6	-3.1	-1.4	2.4	3.1	1.7	1.1	3.7	2.0	-0.6	1.2
Number of full sisters	0.9	1.1	2.8	1.7	0.6	-1.0	-1.3	1.1	0.6	1.1	0.1	1.0	1.3	0.6	1.2
Medication: Aspirin	0.9	1.2	4.9	-1.3	-2.0	-0.3	0.1	0.5	-1.2	-2.2	0.1	-0.7	-0.4	-0.0	-1.0
Illnesses of father: Heart disease	0.9	1.3	4.7	-0.9	1.6	1.3	1.3	2.2	-0.4	0.0	0.3	-1.2	-0.3	-0.7	-1.4
Whole body fat-free mass	0.9	5.2	14.1	0.2	-2.0	-3.6	-1.6	3.1	3.2	1.4	0.6	3.8	2.0	-1.0	1.2
Leg fat-free mass (right)	0.9	4.7	12.1	0.5	-2.1	-3.4	-1.3	3.1	3.0	1.2	0.0	3.5	1.7	-1.2	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.5	1.6	0.0	-1.0	-0.5	0.8	1.3	0.9	-0.1	1.3	1.0	1.1	1.5
Whole body water mass	0.9	5.1	14.0	0.2	-2.1	-3.6	-1.6	3.1	3.2	1.4	0.5	3.7	1.9	-1.1	1.1
Leg predicted mass (right)	0.9	4.6	12.1	0.4	-2.2	-3.4	-1.3	3.1	3.0	1.2	-0.1	3.5	1.6	-1.4	1.1
Medication: Atorvastatin	0.9	1.2	4.1	-1.3	-0.7	1.2	1.1	-0.7	-0.2	-2.0	-0.9	-0.5	-0.9	-1.6	-0.4
Chronotype (morning person)	0.8	1.9	7.3	-1.6	-1.9	-0.4	0.2	-2.7	-1.3	-1.3	0.4	-1.2	-1.2	-1.3	-1.1
Relative age of first facial hair	0.8	1.6	8.5	0.4	-0.4	1.3	-0.6	0.7	-0.7	0.3	1.4	-0.6	1.6	2.9	1.7
Allergy	0.8	1.8	4.7	-1.3	1.2	1.5	0.8	0.9	-2.2	-1.1	0.0	-2.2	-0.6	-0.3	-1.8
Trunk fat-free mass	0.8	4.7	12.7	-0.1	-2.1	-3.4	-1.4	2.9	3.0	1.2	0.6	3.6	1.8	-1.1	0.9
Father’s age at death	0.8	1.1	2.7	-0.4	-1.5	1.6	1.6	1.1	-1.0	-0.5	-1.3	-0.9	-0.4	0.1	-0.6
Hair/balding pattern: Pattern 3	0.8	1.2	3.5	-1.4	-1.5	1.9	0.8	0.9	-1.1	-0.8	-1.0	-0.8	0.9	-0.8	-0.3
Trunk predicted mass	0.8	4.6	12.5	-0.1	-2.1	-3.5	-1.5	2.8	3.0	1.2	0.6	3.5	1.9	-1.1	1.0
High blood pressure (siblings)	0.8	1.1	2.5	-1.3	-1.2	0.7	1.6	-0.9	-0.3	-0.6	0.4	-1.0	-1.5	-0.4	-1.4
Wheeze or whistling in the chest in last year	0.8	1.5	6.5	0.5	-1.5	-2.5	-0.7	-0.9	1.8	-0.5	0.7	1.4	0.2	-0.5	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.5	-0.0	-1.9	1.5	1.1	-0.6	-1.0	-1.3	-0.5	-1.1	0.1	0.2	-0.3
Comparative height size at age 10	0.8	4.2	22.5	-2.1	-1.7	1.5	2.5	-0.2	-0.2	0.0	-3.3	0.4	-0.5	-4.7	-0.8
Age at last live birth	0.8	1.2	5.0	-2.2	-1.1	-0.2	-0.2	-0.8	-0.1	-1.2	0.2	-0.1	-1.4	-0.8	-1.9
Commuting to job workplace: Walk	0.8	0.9	2.4	-0.9	0.6	-1.5	0.2	-1.3	0.8	0.3	1.5	0.8	-1.0	-0.3	-0.6
Eye problems/disorders: Glaucoma	0.8	0.9	3.3	1.2	0.0	-1.4	-1.8	-1.6	-0.5	0.1	-0.4	-0.3	-1.0	0.0	0.1
Ever smoked	0.8	1.4	5.7	1.3	-0.7	-2.4	-2.1	-0.9	0.3	-1.5	0.0	-0.0	0.1	1.1	0.6
Diastolic blood pressure, automated reading	0.8	2.6	7.7	1.1	0.7	-2.5	-2.1	-1.8	1.4	1.0	2.8	1.1	0.9	1.5	1.0
Heart disease (siblings)	0.8	0.9	3.7	0.5	-1.4	-0.2	0.8	0.1	1.6	0.5	0.4	1.9	0.5	0.7	0.9
Mean Putamen Volume	0.7	0.7	4.4	-0.7	0.1	0.2	0.4	2.1	-0.3	0.5	1.6	0.2	0.5	0.8	0.2
Average weekly spirits intake	0.7	0.9	3.4	-0.8	-0.3	-0.0	0.1	0.8	-0.0	-1.0	0.2	-0.7	-1.5	-1.3	-1.8
Sensitivity / hurt feelings	0.7	1.2	4.6	1.0	2.1	0.1	0.3	2.0	0.9	0.9	-0.2	0.4	-1.1	0.7	-1.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	3.3	0.8	-0.7	-0.4	-1.8	-1.3	0.5	0.4	-1.2	0.6	0.4	0.0	0.5
Medication: Metformin	0.7	0.9	8.4	0.3	0.0	-0.8	-0.4	2.9	0.9	0.4	-0.5	0.7	-0.0	0.4	0.4
Diabetes (mother)	0.7	0.9	3.0	-0.9	0.2	0.9	1.7	1.4	0.2	0.1	-0.8	-0.2	-0.4	-1.7	-1.0
Hand grip strength (right)	0.7	1.9	5.3	0.1	-1.9	1.8	1.0	0.2	-1.6	-2.3	-2.1	-1.1	-0.2	-1.2	-0.8
Medication: Atenolol	0.7	0.9	2.8	0.3	1.5	1.2	1.1	-0.1	1.7	0.8	-1.3	0.5	-0.4	-0.3	0.0
Medication: Ramipril	0.7	0.9	4.6	1.3	-1.3	0.9	1.0	-0.5	0.8	-0.6	-2.1	-0.1	0.0	-0.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.5	-0.5	-1.2	0.5	1.3	0.6	-1.1	-1.3	-1.9	-1.4	-1.4	-1.2	-1.7
Exposure to tobacco smoke at home	0.7	0.8	3.1	-0.5	0.0	-1.8	-0.8	-0.8	1.2	-0.0	1.3	0.9	-0.7	0.6	0.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.8	1.7	0.6	-1.0	-1.2	1.4	0.2	1.1	0.5	0.4	1.4	0.8	1.4
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.8	0.1	1.3	-0.1	1.0	-0.0	1.5	1.0	-0.7	1.7	-0.6	-1.0	0.2
Eye problems/disorders: None of the above	0.7	0.8	2.7	-1.4	-1.7	-0.0	0.9	0.9	-0.3	-1.1	0.3	-0.9	0.1	0.5	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.7	0.0	-1.0	-1.5	-1.6	-0.1	-0.6	-0.1	0.5	0.1	0.1	1.2	1.2
Suffer from ‘nerves’	0.7	1.1	4.0	-1.4	0.4	-0.1	-0.6	-1.1	0.7	0.5	0.6	0.6	-1.9	-0.5	-2.0
Knee pain experienced in last month	0.7	1.1	3.8	1.3	0.2	-0.3	0.4	0.5	0.0	0.7	-0.3	0.8	1.6	1.7	1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.2	0.6	1.5	-1.3	-0.6	0.5	0.8	0.9	1.3	1.4	-0.3	0.4	-0.3
Loneliness, isolation	0.7	0.9	4.7	0.3	1.6	-0.2	-0.2	2.2	0.8	0.9	0.3	0.7	1.0	0.7	0.2
Myopia	0.7	1.0	4.9	-0.4	-0.0	-1.3	-2.2	1.2	0.4	0.4	-0.1	1.2	1.1	-0.3	0.5
Cholesterol lowering medication	0.7	1.1	5.1	0.0	0.2	0.3	0.0	2.3	1.9	0.4	0.7	0.6	0.6	1.6	0.6
Schizophrenia (2018)	0.6	1.3	5.2	1.1	2.3	0.4	0.8	1.9	0.2	0.8	1.1	1.1	1.1	0.1	0.5
Irritable Bowel Disease (IBD)	0.6	1.5	3.6	-0.4	-1.2	1.9	0.4	-1.4	-1.0	-1.9	-1.5	-0.9	-0.2	-1.5	-0.9
Bipolar Disorder (2011)	0.6	0.6	2.0	-1.0	0.0	1.0	-0.2	-1.4	-1.0	-0.5	-0.8	-0.3	0.2	-1.2	-0.1
Fasting Glucose	0.6	0.7	2.0	-0.6	1.4	0.1	-0.5	-0.2	0.6	1.1	0.9	0.8	1.3	-0.3	0.7
Schizophrenia (2014)	0.6	1.3	4.9	1.0	2.2	1.0	1.3	1.6	0.1	1.1	-0.1	1.2	1.1	-0.5	0.9
Systolic blood pressure, automated reading	0.6	1.7	12.3	1.1	0.8	-0.6	-0.6	-3.5	1.2	0.8	0.8	0.9	0.5	1.0	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	2.9	0.8	-1.1	-1.2	-0.1	1.5	0.9	-0.4	0.1	1.7	0.6	0.5	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	5.6	1.0	0.5	-0.1	-0.2	2.4	-1.3	-0.0	1.6	-1.1	0.4	1.6	0.4
Alcohol usually taken with meals	0.6	0.9	4.8	0.0	-0.2	-0.4	0.2	1.6	-0.3	0.0	1.8	-0.5	-0.1	2.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	7.5	1.0	0.8	-0.0	-0.0	2.7	-1.2	0.1	1.6	-0.9	0.1	1.8	0.3
Qualifications: None of the above	0.6	1.3	2.9	1.0	-0.1	-1.7	-0.8	-1.6	1.0	0.5	0.8	1.5	1.3	0.8	1.5
Pain all over the body in last month	0.6	0.7	3.1	-1.4	0.5	-0.5	-0.1	-0.2	1.0	0.0	-0.8	0.7	0.2	-1.8	-0.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	5.8	0.3	-2.4	-0.9	-0.1	-0.7	0.1	-0.6	0.8	-0.3	-0.8	0.7	0.3
Worrier / anxious feelings	0.6	1.1	3.1	0.4	1.3	0.5	0.8	1.4	1.4	1.2	1.0	1.1	-0.1	1.8	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.5	1.2	0.8	-0.5	-0.4	-0.7	0.1	1.1	1.2	0.4	-0.1	1.6	0.1
Length of working week for main job	0.6	0.6	2.3	0.5	1.5	-0.5	-0.3	1.2	0.5	0.6	0.3	1.0	0.4	-0.0	1.2
Tense / ‘highly strung’	0.6	1.0	3.2	0.8	0.9	-1.5	-1.1	-0.0	1.8	1.1	-0.2	1.3	-0.8	0.3	0.3
Pulse wave reflection index	0.6	0.8	3.4	-0.2	-0.0	1.4	1.3	1.8	0.0	0.7	-0.6	0.6	1.0	-0.3	0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.5	-0.1	0.8	-1.4	-0.9	1.6	-0.2	0.5	1.4	-0.4	-0.4	0.9	-0.1
Glaucoma (self-reported)	0.6	0.7	2.9	0.6	0.2	-1.1	-1.7	-1.2	-0.6	0.1	0.7	-0.4	-0.5	0.7	0.4
Medication: Allopurinol	0.6	0.8	3.8	0.0	-0.3	-0.4	0.6	-2.0	-0.3	-0.2	-1.6	0.0	-0.7	-1.5	-0.2
Overall health rating	0.6	1.2	5.4	-0.3	0.0	-1.4	-0.6	1.3	1.8	0.4	0.3	2.3	1.1	0.2	0.9
Smoking status: Previous	0.6	0.9	3.8	1.6	0.5	-0.7	-0.4	-1.2	-0.3	0.3	-0.5	-0.1	1.0	1.9	1.1
Pain experienced in last month	0.6	1.0	3.1	-0.7	-0.9	0.2	-0.7	-0.5	-0.8	-1.6	-0.4	-0.8	-1.1	-1.8	-1.1
Worry (Nagel 2018)	0.5	1.0	4.8	0.1	1.0	0.6	0.7	-0.3	2.2	1.6	0.1	1.6	-0.7	0.3	-0.4
Reaction Time	0.5	1.0	3.8	0.8	-0.5	-1.1	-1.9	0.2	0.9	-0.1	-0.3	1.9	0.8	-0.1	0.9
Coronary Artery Disease (CAD)	0.5	0.6	4.1	-0.5	0.4	-0.7	-0.7	-0.0	0.5	0.1	1.0	2.0	0.1	0.3	0.5
Ulcerative Colitis	0.5	0.8	3.3	-0.5	-0.4	1.0	-0.1	-0.8	-0.9	-1.8	-0.6	-0.9	-0.7	-0.3	-1.1
Lung FEV1/FVC ratio	0.5	2.5	13.7	-0.6	-2.0	0.1	0.8	3.7	-2.1	-1.1	1.8	-0.4	0.5	1.5	-0.1
Lung FVC	0.5	2.6	11.2	0.1	-1.8	-0.5	-1.3	3.4	-1.4	0.1	2.2	0.3	2.2	0.8	1.5
Number of treatments/medications taken	0.5	0.9	2.6	-1.6	-0.3	-0.3	1.4	-1.6	0.5	-0.9	0.3	0.5	-1.0	-0.4	-1.0
Vitamin and mineral supplements	0.5	0.6	3.8	-0.3	0.2	-0.1	-0.9	-1.9	-0.1	-0.4	-1.0	-0.3	0.1	-1.0	-0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.8	0.4	-0.0	0.4	1.3	0.5	0.0	-0.5	-1.1	0.0	-1.4	-1.2	-0.6
Serious illness, injury or assault to yourself	0.5	0.6	1.8	-0.7	0.3	1.3	1.1	0.1	0.6	1.2	-0.3	0.3	0.5	-1.3	0.0
Multivitamins +/- minerals	0.5	0.7	4.0	0.2	0.2	-0.2	0.7	2.0	0.4	0.7	1.1	0.0	0.2	1.1	0.4
Number of incorrect matches in round	0.5	0.8	2.0	-0.5	-0.5	0.8	1.4	-1.4	0.3	0.3	-1.0	0.9	-0.6	-1.3	-0.5
Past tobacco smoking	0.5	1.0	3.2	-1.6	0.1	1.8	1.2	1.2	-0.6	0.7	0.8	-0.4	-0.1	-1.0	-0.6
Had menopause	0.5	0.6	1.5	0.6	0.5	1.0	0.9	1.2	1.0	0.4	0.5	1.2	-0.1	0.3	0.2
Time employed in main current job	0.5	0.6	2.4	-0.8	0.1	-1.5	-0.3	-0.4	0.8	0.7	1.5	0.4	0.1	0.3	-0.0
Prospective memory result	0.5	0.6	1.7	0.7	-0.0	-0.4	-0.1	0.7	0.7	0.9	1.3	0.8	0.8	0.6	1.0
Illnesses of mother	0.5	0.7	2.2	0.9	1.5	0.3	0.3	-0.9	1.2	1.1	-0.3	0.9	0.6	0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.4	4.6	-1.8	-1.2	0.5	-0.5	2.2	-1.9	-0.2	1.3	-0.4	-0.2	-1.0	-0.7
Gout (self-reported)	0.5	0.7	3.6	0.5	-0.4	-1.0	-0.2	-1.9	-0.0	0.6	-0.7	0.8	0.3	-0.2	1.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.0	-1.0	-0.6	-0.2	0.4	1.1	0.3	-0.8	-0.5	1.2	-0.1	-1.4	0.0
Mean time to correctly identify matches	0.5	1.0	4.0	0.8	-0.7	-1.0	-1.2	0.9	0.9	-0.2	-0.1	2.0	1.1	0.5	1.3
Alcohol intake frequency.	0.5	1.2	4.0	1.9	0.5	-0.7	-0.3	-0.6	1.3	2.0	-0.2	1.8	0.3	-0.6	0.7
Supplements: Vitamin C	0.5	0.6	1.8	-0.8	-0.3	0.3	0.0	1.2	0.6	-0.1	0.6	0.3	-1.3	-1.1	-1.3
Average weekly red wine intake	0.5	0.7	5.0	-0.1	-0.6	0.4	0.2	2.2	0.6	-0.0	0.4	0.7	0.1	1.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.2	-1.5	-0.3	-0.6	0.3	0.9	0.8	0.5	-0.2	0.8	0.1	-1.0	0.0
Eye problems/disorders: Cataract	0.5	0.6	2.8	1.1	1.7	1.1	0.2	0.3	-0.9	0.3	0.1	-0.9	0.1	-0.3	0.1
Medication for cholesterol	0.5	0.7	2.1	0.6	-0.8	-0.9	-1.4	-1.5	-1.0	-0.2	0.9	0.4	0.1	0.6	0.7
Wears glasses or contact lenses	0.5	0.6	1.9	-0.9	-0.7	0.1	0.4	0.9	-1.3	-0.8	-0.4	-1.4	0.0	-0.6	-0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.1	0.1	-1.0	-1.5	-0.3	-0.8	0.8	0.2	0.9	1.1	-0.5	-0.5	-0.2
High cholesterol (Self-reported)	0.5	1.0	3.8	-2.0	0.0	1.4	0.9	0.2	0.0	-1.5	-0.5	-1.0	-0.9	-0.0	-0.7
Irritability	0.5	0.9	4.2	1.1	0.7	-0.4	-0.1	0.9	2.0	1.1	-0.7	0.9	0.6	0.5	0.7
Age started oral contraceptive pill	0.5	0.6	1.7	-1.1	-0.4	1.3	0.9	0.1	-0.7	-0.9	-0.6	-0.6	-0.3	-0.1	-1.0
Bipolar Disorder or Schizophrenia	0.4	0.9	5.0	0.6	2.2	0.6	0.9	0.8	0.3	0.9	0.9	1.2	1.0	-0.2	0.3
Schizophrenia vs Biploar Disorder	0.4	0.6	4.2	-0.1	1.1	-0.7	0.4	2.0	-0.1	-0.0	0.7	0.2	-0.6	-0.2	-0.5
Prostate Cancer	0.4	0.6	2.6	-1.3	-0.7	0.1	0.0	-0.9	-1.6	-0.2	0.4	-1.0	-0.3	-0.6	-0.6
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.9	0.3	-0.2	-1.1	-0.2	1.7	-0.0	-0.6	0.9	0.1	-0.1	1.0	-0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.8	-1.4	-0.8	0.7	0.7	0.8	0.2	-0.6	-0.2	0.0	-0.8	-0.3	-1.0
Average weekly fortified wine intake	0.4	0.4	2.7	0.4	-0.1	-0.5	-1.6	-0.7	-0.8	-0.4	0.2	-0.1	-0.9	-0.2	-0.1
Supplements: Glucosamine	0.4	0.5	1.9	-1.4	-1.0	-0.4	-0.1	-0.4	0.3	-0.7	0.5	0.6	-0.5	0.6	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.5	3.6	0.1	0.1	0.5	0.5	1.9	0.8	0.0	-0.7	1.0	-0.2	0.5	0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.7	-0.4	0.1	-1.3	-0.1	-1.1	0.9	0.9	0.2	1.2	-0.0	-0.1	0.3
Financial difficulties in last 2 years	0.4	0.5	1.5	0.9	-0.2	-0.6	0.7	-0.6	0.7	0.7	-0.8	1.2	0.3	-0.1	1.0
Heart attack	0.4	0.5	1.4	0.7	0.4	0.8	1.1	0.3	0.9	1.2	-0.1	0.9	-0.2	-0.1	0.7
Illnesses of siblings	0.4	0.6	2.0	0.7	0.7	0.1	-1.4	0.9	-0.9	-0.3	-1.2	-0.7	0.3	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.0	-1.2	-1.2	0.3	-0.6	2.1	-2.2	0.3	1.5	-0.4	0.8	-0.4	0.1
Noisy workplace	0.4	0.5	1.8	-0.5	-1.1	-0.3	-0.0	-0.9	0.3	-0.7	-0.1	-0.1	-1.3	-0.7	-0.6
Lung cancer (father)	0.4	0.5	3.6	1.9	0.7	-0.5	-0.2	-0.4	-0.3	0.3	-0.3	-0.3	0.4	0.5	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.1	-0.4	0.7	0.8	1.4	-0.4	0.5	0.5	-0.5	0.1	-0.9	-0.6	-1.2
Hair/balding pattern: Pattern 4	0.4	0.9	2.3	0.9	1.4	-0.4	-0.3	1.1	1.0	0.9	1.0	1.5	0.0	0.9	0.7
Loud music exposure frequency	0.4	0.5	1.2	0.8	0.4	-1.0	-1.1	0.2	0.8	0.3	-0.2	1.1	-0.3	-0.4	0.5
Medication: Paracetamol	0.4	0.7	1.8	-0.4	-0.1	0.2	0.5	-1.4	1.4	1.0	0.3	1.2	1.0	0.6	0.5
Medication: Amlodipine	0.4	0.6	2.1	-1.0	-0.3	0.4	0.7	-0.1	1.2	-0.5	1.4	0.2	0.5	1.0	-0.3
Birth weight	0.4	0.9	3.1	-0.8	-1.8	0.1	-1.2	-1.0	-1.3	-0.9	-0.6	-0.4	-0.5	-0.7	-0.4
Heart disease (mother)	0.4	0.5	1.9	-0.4	-1.4	-0.8	-0.3	1.0	0.0	-1.0	0.7	0.1	-0.7	-0.2	-0.5
Chest pain or discomfort	0.4	0.6	3.4	0.9	0.5	-1.8	-1.0	-0.0	0.9	0.9	0.3	0.3	-0.5	0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.9	-1.4	-0.4	0.8	0.3	-0.1	-1.0	-0.2	-0.7	-1.3	-0.0	-1.7	-0.9
Supplements: Fish oil (including cod liver oil)	0.4	0.6	3.5	0.5	-0.3	0.1	0.9	-1.9	0.5	0.2	-1.0	0.4	-0.7	-0.1	0.3
Medication: Paracetamol	0.4	0.7	2.7	-0.9	0.0	-0.4	-0.4	-1.6	1.2	0.7	0.4	1.3	0.1	0.3	0.4
Commuting to job workplace: Cycle	0.4	0.5	2.2	-0.6	-0.0	-0.7	-0.4	-0.8	1.5	-0.1	0.7	0.8	-0.3	-0.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.4	0.5	0.3	0.8	1.2	-0.1	0.9	1.1	-0.2	1.0	0.1	-0.2	0.8
Intelligence (Savage-Jansen 2018)	0.3	1.1	8.3	0.3	-1.2	-0.7	-0.2	2.9	0.5	-0.8	-0.5	-0.4	-0.3	0.8	0.2
Major Depression (MDD)	0.3	0.4	1.3	-0.3	0.7	-0.1	0.6	0.6	1.1	0.8	0.0	1.0	-0.1	-0.1	-0.2
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.8	0.4	0.2	-0.3	0.0	2.0	1.2	0.6	-1.0	1.0	0.2	0.9	0.7
HDL Cholesterol	0.3	0.5	3.1	-0.3	-1.0	-0.9	-0.4	-1.8	0.4	-0.2	-0.1	0.6	-0.2	-0.7	0.6
Lupus	0.3	0.5	1.5	-0.5	-1.2	0.4	1.2	-0.5	-0.1	1.2	-0.1	-0.3	-0.3	-0.6	0.1
Rheumatoid Arthritis	0.3	0.4	1.7	0.3	0.8	0.3	0.5	1.3	-0.1	-0.0	0.3	-0.2	-0.8	-0.8	-0.2
Triglycerides	0.3	0.5	1.4	0.6	-0.6	0.5	-0.7	0.6	-1.2	-0.7	0.1	-0.5	1.1	0.3	0.6
Blood White Count	0.3	2.4	9.0	2.0	1.8	-1.9	-1.4	1.2	0.2	1.0	3.0	-0.0	0.8	1.8	1.2
Heel T-Score	0.3	2.3	10.6	0.3	2.3	1.5	0.7	3.3	-1.8	0.2	1.1	-0.5	0.6	1.9	-0.2
Waist Hip Ratio (WHR)	0.3	1.2	9.4	-0.5	1.5	0.0	-1.3	-3.1	-0.6	-0.6	0.0	-0.7	-0.5	-0.1	0.2
Hypothyroidism (self reported)	0.3	0.7	2.1	-1.0	-1.3	0.7	0.1	0.0	-0.8	-1.4	-0.2	-0.0	-0.2	-1.3	-0.8
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.3	0.2	-0.3	-0.6	0.1	-0.6	0.3	-0.6	1.1	0.1	-1.5	-0.1	-0.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.7	-0.6	0.6	0.3	-0.5	-0.6	-0.1	-0.6	0.3	0.2	-0.5	-1.3	-0.2
Severe depression (siblings)	0.3	0.4	1.2	0.5	0.7	-1.1	-0.6	1.1	0.8	0.4	-0.6	0.1	0.1	-0.1	0.1
Age when periods started (menarche)	0.3	0.7	2.5	-0.3	-0.3	-0.0	-0.3	-1.1	-1.0	-0.9	0.7	-1.6	-0.8	1.0	-0.5
Qualifications: CSEs or equivalent	0.3	0.4	2.0	-0.5	0.0	-0.4	-0.8	-1.4	0.5	-0.5	-0.1	-0.3	-0.1	-0.9	-0.8
Stomach or abdominal pain in last month	0.3	0.4	1.5	-0.2	-0.3	-1.2	-1.0	-0.3	0.1	0.0	0.9	0.8	-0.2	0.4	0.6
Mouth/teeth dental problems	0.3	0.5	2.0	0.3	-0.6	0.8	0.6	1.1	-0.6	0.1	-0.5	-0.2	1.4	-0.5	0.5
Medication: Simvastatin	0.3	0.4	1.5	-1.2	-0.1	0.2	0.0	-0.4	0.4	-0.1	0.8	-0.6	-1.2	0.5	-0.5
Fluid intelligence score	0.3	0.6	2.6	0.1	0.8	-0.2	-0.7	1.2	0.4	0.7	-1.6	0.7	-0.5	-0.3	0.2
Asthma	0.3	0.6	3.1	0.0	-0.6	-0.8	-0.3	-1.4	-0.2	-0.6	-0.8	0.2	-0.4	-1.8	0.1
Pulse wave Arterial Stiffness index	0.3	0.4	1.2	-0.3	-0.3	0.7	0.4	0.7	-0.1	-0.4	-1.1	-0.8	-0.5	-0.8	-0.6
Standing height	0.3	2.5	11.5	-2.1	0.1	0.7	1.7	1.8	0.5	0.1	-1.8	0.5	-0.7	-3.4	-1.7
Breastfed as a baby	0.3	0.4	0.8	0.8	0.9	0.4	0.0	0.4	-0.9	-0.9	-0.4	-0.7	-0.8	0.2	0.1
Birth weight of first child	0.3	0.6	2.5	-0.6	-0.1	-1.4	-1.6	-0.5	0.2	0.4	0.6	0.0	0.3	0.7	0.7
Forced vital capacity (FVC), Best measure	0.3	1.1	3.8	-1.9	-0.9	0.5	-0.4	1.5	-1.3	0.1	0.6	-0.4	-0.3	-1.8	-0.8
Number of full brothers	0.3	0.3	1.8	-1.0	-1.4	-0.2	-0.3	-0.1	-0.1	-0.2	-0.2	0.3	0.1	-1.0	-0.2
Pulse wave peak to peak time	0.3	0.3	0.9	0.3	0.2	-0.8	-0.5	-0.4	0.2	0.4	0.9	0.8	0.5	0.5	0.5
Medication for pain relief, constipation, heartburn	0.3	0.4	1.8	0.9	-0.6	0.1	-0.9	-0.3	-0.2	-0.4	0.3	-1.3	-0.9	-0.4	-0.0
Neck or shoulder pain in last month	0.3	0.4	2.1	0.4	0.5	-0.1	0.1	-0.5	0.1	0.2	0.7	0.8	0.2	1.4	0.8
Medication: Blood pressure	0.3	0.6	2.1	-0.8	-0.9	-0.4	-0.2	-1.4	0.6	-0.6	1.0	0.0	-0.8	0.4	-0.6
Pulse rate, automated reading	0.3	0.8	1.8	-0.8	-1.2	0.7	0.3	-1.0	-0.5	-1.2	-1.1	-0.9	0.3	-1.4	-0.6
Qualifications: nursing, teaching	0.3	0.5	2.8	0.3	0.3	0.8	1.7	0.8	0.4	0.1	0.3	-0.7	0.1	0.4	-0.1
Mineral and other dietary supplements	0.3	0.4	1.9	0.6	0.4	-0.3	-0.9	1.4	-0.0	-0.0	0.2	-0.5	0.9	0.3	-0.1
Breast cancer (self-reported)	0.3	0.4	1.2	-1.1	-0.8	0.2	1.0	-0.4	-0.7	-0.7	-0.2	0.1	0.2	-0.5	0.0
Asthma (self-reported)	0.3	0.6	2.2	0.3	-0.7	-1.2	-0.5	-1.3	-0.3	-0.7	-0.6	0.1	-0.3	-1.5	0.2
Financial situation satisfaction	0.3	0.3	1.0	1.0	-0.2	-0.9	0.1	0.2	1.0	0.3	0.2	0.5	-0.1	0.7	0.0
Medication: Blood pressure	0.3	0.6	2.1	1.5	0.2	0.1	0.5	0.8	1.3	-0.1	-0.6	0.7	0.9	0.7	0.4
Medication: Bendroflumethiazide	0.3	0.4	1.4	0.5	-0.2	-0.9	0.3	0.4	0.8	-0.4	-0.0	-0.4	0.8	1.2	0.8
Risk taking	0.3	0.5	2.0	-0.5	0.0	-0.7	-0.5	-1.4	0.8	-1.0	-0.1	0.3	-0.5	-0.8	-0.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.3	0.1	-0.8	0.1	0.5	-0.5	-1.1	-0.8	-0.2	-0.8	-0.2	0.1	0.0
Bipolar Disorder (2018)	0.2	0.3	1.1	-0.4	0.8	0.5	0.4	-1.0	0.2	0.4	-0.1	0.5	0.6	-0.6	-0.2
Breast Cancer	0.2	0.4	1.5	-0.3	1.0	-1.0	-0.1	-0.2	0.3	0.7	-0.9	1.2	0.3	-0.5	-0.1
Blood Platelet Count	0.2	2.2	5.5	0.1	1.0	0.0	0.4	1.3	-0.6	1.9	2.3	-1.4	2.0	2.4	1.4
Height	0.2	4.1	13.3	-1.2	0.4	0.2	2.1	2.9	1.9	1.7	-2.8	2.5	0.4	-3.6	-0.5
Cardiovascular Disease	0.2	0.5	5.0	-0.3	0.4	0.4	-0.4	-2.2	-0.0	-0.8	0.1	-0.3	0.0	-0.2	-0.2
Respiratory disease	0.2	0.5	1.6	0.1	0.2	-0.4	-0.3	-1.1	0.3	-0.0	-1.1	0.7	0.3	-1.3	0.5
Taking other prescription medications	0.2	0.3	1.6	-0.5	0.2	0.3	1.2	0.8	0.7	0.0	0.0	0.3	-0.2	-0.3	-0.3
Medication: Levothyroxine sodium	0.2	0.4	1.4	-0.4	-0.2	0.8	-0.1	-0.2	-0.7	-1.2	0.4	-0.2	-0.7	-0.9	-0.8
Sitting height	0.2	1.2	6.9	-1.2	-0.0	-0.2	0.9	1.4	0.8	0.4	-1.2	1.0	0.1	-2.6	-0.5
Forced vital capacity (FVC)	0.2	0.9	3.0	-1.3	-1.0	0.3	-0.4	1.7	-1.5	0.5	1.0	-0.3	0.8	-1.0	0.2
Pulse rate	0.2	0.4	1.2	0.5	-0.2	0.6	1.1	-1.0	-0.3	-0.2	-0.5	-0.8	0.6	-0.1	0.6
Peak expiratory flow (PEF)	0.2	0.5	2.1	-0.2	0.1	-0.7	-1.2	0.6	-1.5	0.5	1.1	0.3	0.2	0.1	0.2
Headache pain in last month	0.2	0.3	1.1	0.1	-0.3	-0.2	-0.3	-0.9	1.1	1.0	-0.7	0.6	-0.1	0.2	0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.5	-0.6	-0.6	0.6	0.2	0.6	-0.5	-1.2	0.4	0.2	-0.2	-0.3	-0.8
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.8	-0.9	-0.7	-0.7	0.5	0.2	-0.3	0.3	-0.2	0.4	0.6	0.5
Health satisfaction	0.2	0.2	1.0	0.1	0.1	-0.0	0.5	-0.4	0.3	0.1	-1.0	-0.1	-0.4	-0.9	-0.1
Qualifications: College or University degree	0.2	0.6	4.0	0.8	-0.2	0.2	-0.7	2.0	-1.0	-0.0	-0.8	-0.3	-0.4	0.5	-0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.3	-0.2	-0.2	0.1	-0.2	-0.4	-0.6	-0.3	-1.2	-0.3	0.5	-0.6	0.5
Hypertension (Self-reported)	0.2	0.6	2.2	0.7	-0.1	-0.6	-0.4	-1.2	0.6	-0.5	0.7	0.3	1.1	1.5	0.6
Osteoporosis (self-reported)	0.2	0.3	1.1	-0.7	1.1	0.1	0.0	-0.4	0.9	0.3	0.1	0.2	-0.3	-0.6	-0.3
Number of self-reported non-cancer illnesses	0.2	0.3	1.5	-0.5	0.2	-0.3	0.5	-0.7	1.2	-0.1	-0.1	1.0	-0.5	-0.1	-0.3
Medication: Lisinopril	0.2	0.3	1.1	-0.4	-0.1	-0.9	-0.0	-1.0	0.8	-0.8	0.6	0.1	0.2	-0.0	0.2
Number of operations (self-reported)	0.2	0.4	1.1	-0.8	-0.4	0.2	0.7	1.1	0.2	-0.8	0.5	-0.0	-0.5	-0.3	-0.6
Average weekly beer plus cider intake	0.2	0.3	1.1	0.4	-0.1	-0.6	-0.3	-1.0	-0.7	0.6	0.1	-0.1	0.6	0.2	0.5
Ever depressed for a whole week	0.2	0.2	0.7	-0.5	-0.3	-0.9	-0.1	-0.1	-0.3	0.1	0.3	0.6	0.6	0.4	0.6
Ulcerative Colitis (UC)	0.1	0.2	1.0	0.1	-0.2	1.0	-0.1	-0.6	-0.1	-0.4	-0.3	-0.2	0.4	-0.5	-0.3
Blood Eosinophil Count	0.1	0.7	1.7	1.0	1.3	-0.7	-0.7	1.2	0.2	0.9	1.2	0.6	-0.5	-0.1	0.4
Blood Red Count	0.1	0.9	3.0	1.7	1.6	0.3	-0.2	-0.0	1.2	-0.4	-1.4	0.6	0.4	-0.4	0.7
Tanning	0.1	0.8	2.2	0.9	1.5	-1.5	-1.4	-0.4	0.4	0.2	0.7	1.0	0.1	0.5	0.8
High blood pressure	0.1	0.4	1.7	0.4	-0.0	-0.3	0.1	-1.3	0.5	-0.5	0.6	0.3	0.9	1.0	0.4
High blood pressure (mother)	0.1	0.1	0.4	-0.3	0.3	0.6	-0.1	0.4	-0.7	0.1	-0.2	-0.0	0.3	0.2	0.2
Back pain experienced in last month	0.1	0.2	0.5	-0.0	0.3	-0.7	0.1	-0.5	0.6	0.5	-0.1	0.7	0.2	-0.0	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	1.3	-0.2	-0.0	-0.0	-0.5	1.1	-0.3	0.6	-0.1	-0.1	-0.4	-0.4	0.1
Hair Pigment	0.0	0.9	3.8	0.2	-0.2	-0.2	-1.5	1.3	-0.1	0.7	1.5	0.0	0.6	1.9	0.1

Hub : Genes

SFXN3

Models

Trait associations