TWAS
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Traits
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Traits
:
Whole body fat-free mass
:
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chr1:48,301,764-52,135,979
Best TWAS P=1.8e-16 · Best GWAS P=4.54e-19 conditioned to 0.000118
48.5M
49M
49.5M
50M
50.5M
51M
51.5M
52M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Gastroesophageal Junction
CDKN2C
0.14
0.11
enet
17
0.12
0.00003
8.8
-8.2
1.8e-16
-0.86
0.02
0.93
TRUE
2
METSIM
Adipose
AGBL4
0.02
0.02
lasso
5
0.02
0.00126
5.6
-5.7
1.2e-08
0.02
0.90
0.00
TRUE