Best TWAS P=1.8e-16 · Best GWAS P=4.54e-19 conditioned to 0.000118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 0.00003 | 8.8 | -8.2 | 1.8e-16 | -0.86 | 0.02 | 0.93 | TRUE |
| 2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 0.00126 | 5.6 | -5.7 | 1.2e-08 | 0.02 | 0.90 | 0.00 | TRUE |