Best TWAS P=2.02e-08 · Best GWAS P=4.16e-08 conditioned to 0.0056
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | CD151 | 0.27 | 0.10 | enet | 47 | 0.10 | 5.5e-06 | -4.4 | 5.2 | 2.0e-07 | -0.49 | 0.27 | 0.65 | FALSE |
| 2 | GTEx | Testis | POLR2L | 0.16 | 0.03 | enet | 10 | 0.03 | 1.9e-02 | -5.5 | -5.6 | 2.4e-08 | 0.85 | 0.00 | 0.99 | FALSE |
| 3 | METSIM | Adipose | POLR2L | 0.03 | 0.02 | bslmm | 413 | 0.01 | 5.0e-03 | -3.6 | -5.6 | 2.0e-08 | 0.57 | 0.20 | 0.15 | TRUE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PNPLA2 | 0.07 | 0.00 | blup | 51 | 0.03 | 1.4e-04 | -3.6 | 5.5 | 3.2e-08 | -0.61 | 0.01 | 0.50 | FALSE |