TWAS hub - POLR2L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0870	0.0240	3.1e-08	0.086	0.063	0.099	0.091	0.096	1.4e-10	3.5e-08	4.6e-12	3.7e-11	1.1e-11
2	GTEx	Adipose Subcutaneous	0.1850	0.0440	8.5e-09	0.115	NA	0.109	NA	0.004	1.2e-09	NA	3.4e-09	NA	1.5e-01
3	GTEx	Adipose Visceral Omentum	0.2020	0.0680	5.4e-04	0.011	NA	0.013	NA	0.023	8.5e-02	NA	6.7e-02	NA	2.2e-02
4	GTEx	Breast Mammary Tissue	0.1710	0.0620	1.2e-03	0.011	NA	0.023	NA	0.019	8.8e-02	NA	2.4e-02	NA	3.6e-02
5	GTEx	Breast Mammary Tissue (Female)	0.3697	0.1007	1.1e-03	0.010	NA	0.024	NA	0.027	1.5e-01	NA	6.5e-02	NA	5.4e-02
6	GTEx	Cells Transformed fibroblasts	0.1230	0.0360	8.6e-06	0.114	NA	0.072	NA	0.116	7.5e-09	NA	4.7e-06	NA	5.2e-09
7	GTEx	Esophagus Mucosa	0.1680	0.0470	6.3e-05	0.144	NA	0.145	NA	0.144	7.0e-10	NA	5.9e-10	NA	7.0e-10
8	GTEx	Muscle Skeletal	0.0772	0.0253	2.3e-04	0.099	NA	0.092	NA	0.088	6.4e-10	NA	2.8e-09	NA	5.4e-09
9	GTEx	Nerve Tibial	0.1496	0.0485	5.0e-05	0.029	NA	0.037	NA	0.033	3.7e-03	NA	1.1e-03	NA	2.2e-03
10	GTEx	Testis	0.1560	0.0550	1.6e-03	0.027	NA	0.029	NA	-0.006	2.3e-02	NA	1.9e-02	NA	8.4e-01
11	GTEx	Whole Blood	0.0900	0.0410	8.0e-03	0.058	NA	0.028	NA	0.033	4.3e-06	NA	1.2e-03	NA	4.3e-04
12	METSIM	Adipose	0.0344	0.0171	9.7e-03	0.018	0.011	0.006	0.012	0.006	8.5e-04	6.9e-03	3.2e-02	5.0e-03	3.5e-02
13	NTR	Blood	0.1943	0.0270	0.0e+00	0.231	0.209	0.224	0.228	0.230	4.0e-73	2.0e-65	1.1e-70	4.9e-72	9.5e-73
14	YFS	Blood	0.2639	0.0346	0.0e+00	0.188	0.288	0.295	0.296	0.291	4.1e-59	3.1e-95	3.1e-98	2.4e-98	2.3e-96
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0207	0.0127	6.6e-03	0.025	0.017	0.008	NA	0.017	7.9e-04	4.5e-03	3.4e-02	NA	4.7e-03
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0422	0.0222	1.3e-04	0.016	0.026	0.020	NA	0.024	5.7e-03	5.5e-04	2.3e-03	NA	9.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Medication: Lisinopril	10.2	13.2	24.3	-4.1	-3.8	-4.9	-2.3	-1.1	-4.5	2.9	-3.7	-3.8	-4.2	-3.4	-3.2	-3.3	3.2	3.6	-4.2
Impedance of leg (left)	8.1	39.2	59.6	7.3	7.0	5.3	4.7	4.1	6.5	-4.7	6.3	6.9	7.7	6.1	6.3	6.0	-7.1	-6.8	6.1
Pulse wave Arterial Stiffness index	7.8	9.1	13.4	3.2	3.5	2.3	1.5	1.5	2.9	-3.2	3.6	2.7	3.2	3.6	1.3	3.7	-3.4	-3.5	3.4
Medication: Co-codamol	7.2	8.4	12.2	-3.4	-3.4	-3.5	-2.6	-2.0	-3.0	1.7	-2.8	-3.1	-2.9	-2.7	-3.2	-2.7	3.5	2.1	-3.0
Pulse wave peak to peak time	7.1	8.3	13.1	-3.0	-3.2	-2.2	-1.2	-1.3	-2.6	3.3	-3.6	-2.4	-3.1	-3.6	-1.3	-3.6	3.1	3.5	-3.4
Impedance of leg (right)	6.8	32.8	53.6	6.9	6.4	5.1	4.8	3.5	6.2	-3.6	5.5	6.3	7.3	5.1	6.3	5.0	-6.6	-6.0	5.4
Eye problems/disorders: None of the above	5.8	6.7	11.0	-2.8	-2.8	-2.5	-0.7	-2.0	-2.2	2.2	-3.1	-2.8	-2.6	-3.2	-1.9	-3.1	3.3	2.7	-2.5
BMI	5.4	31.5	46.8	-6.8	-6.4	-5.8	-5.1	-3.4	-6.2	2.7	-5.1	-6.3	-6.8	-4.7	-6.8	-4.6	6.6	5.4	-4.9
Leg fat-free mass (left)	5.1	26.9	44.9	-6.1	-5.3	-4.8	-3.7	-2.5	-5.2	3.8	-5.2	-5.0	-6.7	-5.1	-6.2	-5.0	6.2	5.4	-5.2
Leg predicted mass (left)	5.0	26.6	44.3	-6.0	-5.3	-4.8	-3.7	-2.4	-5.2	3.7	-5.1	-5.0	-6.7	-5.0	-6.2	-5.0	6.2	5.4	-5.2
Pulse wave reflection index	5.0	6.1	10.2	2.6	3.0	1.8	0.5	0.3	2.3	-2.6	3.0	2.1	2.5	3.2	1.0	3.2	-3.2	-2.8	2.8
Mother’s age at death	5.0	6.3	11.2	2.5	2.3	2.9	3.3	2.5	2.8	-1.8	2.5	3.0	1.6	2.3	2.6	2.3	-2.3	-1.8	2.7
Impedance of whole body	5.0	25.6	42.3	6.5	6.0	4.9	3.7	2.6	5.9	-2.1	4.5	6.0	6.5	3.9	6.2	3.8	-6.1	-5.0	4.4
Leg fat-free mass (right)	4.7	25.0	43.2	-6.0	-5.0	-4.7	-3.8	-2.3	-5.2	3.3	-4.8	-4.8	-6.6	-4.7	-6.2	-4.6	6.1	5.1	-5.0
Leg predicted mass (right)	4.7	24.9	42.9	-5.9	-5.0	-4.7	-3.8	-2.3	-5.2	3.3	-4.8	-4.8	-6.5	-4.7	-6.2	-4.6	6.0	5.1	-4.9
Body mass index (BMI)	4.4	18.9	32.4	-5.7	-5.3	-4.6	-3.8	-2.7	-4.7	1.3	-3.6	-4.7	-5.4	-3.1	-5.7	-3.1	5.7	3.9	-3.5
High blood pressure (mother)	4.1	5.8	9.5	-2.5	-2.5	-3.1	-1.4	-1.0	-2.3	1.9	-2.5	-2.8	-2.9	-2.6	-2.3	-2.6	2.5	2.5	-2.2
Comparative body size at age 10	4.0	10.9	17.4	-3.9	-2.9	-3.5	-0.7	-1.8	-3.5	2.5	-3.4	-3.1	-4.2	-3.5	-3.8	-3.4	3.9	3.5	-3.3
Relative age of first facial hair	3.8	7.8	10.0	3.2	2.9	2.7	2.6	2.8	3.1	-2.0	2.8	3.1	3.1	2.5	2.8	2.4	-2.6	-3.0	3.1
Arm fat mass (right)	3.7	15.1	26.2	-5.0	-4.7	-4.2	-3.3	-2.0	-4.1	1.4	-3.3	-3.8	-4.8	-3.0	-5.1	-3.0	5.1	3.5	-3.3
Breast Cancer	3.6	8.8	25.5	2.9	2.1	1.6	-0.9	2.9	1.9	-3.3	3.2	2.6	5.0	3.4	1.8	3.4	-1.9	-5.0	2.0
Supplements: Zinc	3.6	3.9	6.1	-1.8	-2.5	-2.0	-2.5	-1.8	-2.0	1.8	-2.1	-1.8	-1.7	-2.0	-1.9	-1.9	1.7	1.8	-2.1
Hip circumference	3.6	15.7	29.5	-5.3	-4.0	-4.3	-3.1	-1.6	-4.2	1.6	-3.4	-3.8	-5.4	-3.1	-5.0	-3.1	5.3	4.1	-3.3
Arm fat mass (left)	3.6	14.7	25.7	-4.9	-4.7	-4.2	-3.4	-2.2	-4.0	1.2	-3.2	-3.8	-4.8	-2.9	-5.0	-2.9	5.1	3.4	-3.2
Basal metabolic rate	3.3	18.5	34.2	-5.4	-4.5	-4.4	-2.8	-1.3	-4.6	2.2	-3.9	-4.2	-5.8	-3.7	-5.8	-3.6	5.4	4.3	-4.0
Ever depressed for a whole week	3.3	4.1	6.2	2.4	2.5	1.4	2.5	1.6	2.2	-1.3	2.1	2.0	2.4	1.9	1.3	1.8	-1.7	-2.5	2.1
Relative age voice broke	3.2	4.8	12.7	2.0	2.9	2.2	1.2	0.9	2.7	-1.8	2.1	2.7	1.8	1.9	3.6	1.9	-1.3	-2.0	2.5
Ever had hysterectomy (womb removed)	3.1	3.5	5.7	-1.4	-1.2	-1.8	-2.3	-1.4	-1.4	2.3	-2.1	-1.9	-1.7	-2.4	-1.4	-2.3	1.4	2.0	-2.0
Weight	3.1	15.4	29.4	-5.0	-4.3	-4.3	-3.1	-1.6	-4.1	1.6	-3.4	-3.7	-5.2	-3.2	-5.4	-3.1	5.2	3.7	-3.4
Medication for cholesterol	3.1	4.8	12.7	2.6	2.5	3.6	2.7	-0.2	3.1	-0.8	1.7	3.0	1.5	1.5	1.7	1.3	-2.4	-1.1	2.2
Whole body water mass	3.1	17.4	32.4	-5.1	-4.2	-4.2	-2.6	-1.1	-4.4	2.4	-3.9	-4.1	-5.6	-3.7	-5.7	-3.6	5.1	4.3	-4.0
Verbal and Numeric Reasoning (VNR)	2.9	6.9	9.6	3.0	2.3	2.5	1.0	1.2	3.1	-2.5	3.0	2.7	2.9	2.8	2.6	2.8	-2.9	-2.6	3.0
Arm fat percentage (right)	2.9	11.4	19.1	-4.2	-4.3	-3.6	-3.2	-2.3	-3.4	1.5	-2.9	-3.2	-4.0	-2.7	-4.1	-2.7	4.4	3.0	-2.9
Medication: Lansoprazole	2.9	3.3	9.2	-2.4	-1.9	-2.4	-2.8	0.1	-1.9	-0.0	-1.0	-1.9	-1.7	-0.8	-3.0	-0.8	2.4	1.1	-1.3
Whole body fat-free mass	2.9	16.8	31.5	-5.1	-4.2	-4.1	-2.5	-1.1	-4.4	2.3	-3.8	-3.9	-5.6	-3.6	-5.6	-3.5	5.0	4.2	-3.9
Arm fat percentage (left)	2.9	11.5	20.9	-4.3	-4.4	-3.7	-3.5	-2.4	-3.5	1.1	-2.9	-3.2	-3.9	-2.6	-4.1	-2.6	4.6	2.9	-2.8
Blood Platelet Count	2.7	31.6	42.8	-5.8	-5.5	-5.3	-0.5	-3.5	-5.8	6.2	-6.3	-5.8	-6.0	-6.5	-5.0	-6.5	5.8	5.9	-6.4
Waist Hip Ratio (WHR)	2.7	12.2	28.6	4.5	2.8	2.5	1.2	2.9	3.8	-2.7	3.3	3.4	5.3	2.9	3.7	2.9	-3.5	-4.9	3.1
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	8.7	-2.2	-2.2	-2.8	-0.7	-0.3	-2.1	2.6	-2.7	-2.0	-2.0	-2.8	-2.7	-2.9	2.7	2.2	-2.9
Average weekly beer plus cider intake	2.7	3.9	7.2	-2.4	-1.8	-2.4	-1.6	-2.1	-2.1	0.8	-1.9	-2.6	-1.9	-1.7	-1.8	-1.7	2.7	1.6	-1.6
Risk taking	2.7	4.0	8.3	-1.8	-1.8	-1.9	-2.9	-2.6	-2.3	1.6	-1.8	-2.0	-1.5	-1.6	-2.4	-1.6	1.7	1.5	-2.1
Length of working week for main job	2.6	2.9	5.4	-1.7	-1.5	-1.5	-0.9	-2.3	-1.6	1.6	-1.8	-1.7	-1.7	-1.8	-1.6	-1.8	1.9	1.7	-1.8
Exposure to tobacco smoke outside home	2.6	3.4	5.6	-2.2	-1.9	-1.5	-0.2	-1.6	-1.9	1.8	-1.9	-1.9	-2.4	-2.0	-1.9	-2.0	1.9	1.9	-1.9
Number of children fathered	2.5	2.8	5.4	-1.7	-1.7	-2.2	-1.0	0.0	-2.2	1.3	-1.8	-2.0	-1.4	-1.6	-1.9	-1.6	1.2	1.3	-2.3
Chest pain or discomfort	2.5	3.5	6.8	2.5	2.1	1.3	0.3	0.6	2.1	-1.6	2.2	1.3	2.6	2.1	0.3	2.0	-2.5	-2.0	2.2
Back pain experienced in last month	2.5	3.7	5.4	-2.2	-2.1	-2.3	-2.1	-0.4	-1.8	1.3	-2.1	-2.2	-1.8	-2.0	-1.8	-2.0	2.2	1.8	-1.9
Pain type(s) experienced in last month: Hip pain	2.5	3.1	6.6	1.8	1.8	1.9	2.0	1.6	1.9	-1.1	1.8	1.6	1.4	1.5	2.6	1.6	-1.7	-1.6	2.0
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	6.1	2.3	2.5	2.2	0.8	-0.2	2.5	-0.4	1.7	2.0	1.4	1.3	2.1	1.3	-2.4	-1.2	1.8
Breast cancer (self-reported)	2.4	2.8	6.7	-2.0	-2.0	-0.6	1.1	-0.7	-1.3	1.2	-1.9	-1.2	-2.6	-1.8	-1.9	-1.7	1.6	2.5	-1.2
Irritability	2.4	4.1	7.1	-1.7	-2.0	-2.4	-2.0	-1.4	-1.9	1.7	-2.3	-2.7	-1.2	-2.3	-2.0	-2.4	2.1	1.5	-2.2
Arm predicted mass (left)	2.4	12.4	29.7	-4.6	-3.7	-3.9	-2.0	-0.6	-3.9	1.1	-2.9	-3.5	-5.0	-2.6	-5.5	-2.5	4.4	3.4	-3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	7.7	1.6	1.4	1.6	2.8	2.0	1.7	-1.6	2.1	2.2	1.1	2.0	1.0	2.0	-2.2	-1.4	2.4
Arm fat-free mass (right)	2.3	11.6	29.9	-4.6	-3.5	-3.7	-2.3	-0.8	-3.8	0.7	-2.7	-3.3	-4.7	-2.3	-5.5	-2.3	4.5	3.0	-2.8
Whole body fat mass	2.3	9.5	19.0	-3.9	-3.7	-3.6	-2.9	-1.2	-3.1	1.0	-2.5	-2.8	-3.9	-2.3	-4.4	-2.3	4.2	2.5	-2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	4.9	1.9	2.0	0.4	-0.3	0.7	2.2	-1.7	1.8	1.1	2.0	1.7	0.5	1.8	-1.6	-2.0	2.2
Arm fat-free mass (left)	2.3	11.8	29.5	-4.6	-3.6	-3.9	-2.2	-0.4	-3.9	0.8	-2.7	-3.4	-4.8	-2.3	-5.4	-2.3	4.4	3.1	-2.9
Mean Putamen Volume	2.2	2.5	5.7	-2.1	-1.6	-2.4	-1.0	0.9	-1.9	0.8	-1.6	-1.9	-1.9	-1.4	-0.6	-1.3	1.4	1.3	-1.8
Osteoporosis (self-reported)	2.2	2.7	5.3	1.9	1.3	1.7	1.0	1.5	1.7	-1.4	1.5	1.5	2.3	1.6	1.8	1.6	-1.5	-2.1	1.5
Ulcerative Colitis (UC)	2.1	3.9	7.4	-2.1	-2.3	-1.6	-2.4	-1.1	-2.3	2.0	-2.0	-1.2	-2.7	-1.8	-2.2	-1.7	0.7	2.7	-2.0
Hearing difficulty/problems with background noise	2.0	3.1	6.5	-2.0	-2.3	-2.5	-0.7	-0.1	-2.2	1.4	-1.8	-1.8	-1.6	-1.7	-1.7	-1.6	1.8	1.5	-1.9
Impedance of arm (left)	2.0	9.4	23.2	4.4	3.9	3.6	2.0	0.7	4.1	0.7	1.8	3.9	3.9	1.1	4.8	1.0	-3.8	-2.2	1.9
Breastfed as a baby	2.0	2.5	6.2	1.6	1.1	0.3	2.4	2.5	1.1	-0.6	1.6	1.9	1.9	1.5	0.4	1.4	-2.5	-1.5	0.8
Leg fat mass (right)	2.0	7.8	17.8	-3.6	-3.4	-3.3	-2.6	-1.2	-2.9	0.4	-2.1	-2.6	-3.4	-1.9	-4.2	-1.9	4.0	2.1	-2.1
Arm predicted mass (right)	2.0	10.4	27.1	-4.3	-3.3	-3.5	-2.1	-0.5	-3.5	0.6	-2.5	-3.0	-4.6	-2.2	-5.2	-2.1	4.3	2.8	-2.6
Eye problems/disorders: Cataract	2.0	2.3	4.0	1.5	1.9	1.8	0.1	1.6	1.4	-1.0	1.7	1.5	1.2	1.6	2.0	1.7	-1.5	-1.3	1.2
Medication: Bendroflumethiazide	2.0	3.1	5.7	-1.8	-1.0	-2.3	-1.4	-0.6	-2.1	1.8	-1.9	-2.1	-1.6	-1.8	-1.3	-1.9	1.8	1.5	-2.4
Leg fat mass (left)	2.0	7.8	19.2	-3.7	-3.4	-3.4	-2.7	-1.1	-2.9	0.1	-1.9	-2.5	-3.5	-1.6	-4.4	-1.7	4.0	2.1	-1.9
Intelligence (Savage-Jansen 2018)	1.9	5.9	9.3	3.1	2.7	2.1	1.1	1.2	3.1	-1.9	2.6	2.4	3.0	2.5	2.1	2.4	-2.9	-2.4	2.6
Trunk fat mass	1.9	8.3	16.7	-3.6	-3.4	-3.3	-2.9	-1.4	-2.7	1.1	-2.4	-2.5	-3.6	-2.3	-4.1	-2.3	3.9	2.5	-2.4
Waist circumference	1.9	6.8	14.4	-3.3	-3.2	-3.2	-2.8	-0.8	-2.7	0.5	-2.1	-2.8	-3.0	-2.0	-3.2	-2.0	3.8	1.9	-2.1
Hair/balding pattern: Pattern 2	1.9	2.4	10.1	-0.2	-0.0	0.0	0.5	2.6	0.0	-3.2	1.9	1.0	0.5	2.4	0.0	2.5	-0.3	-1.6	1.4
Fluid intelligence score	1.9	3.9	5.4	2.0	1.6	1.6	0.4	1.5	2.0	-2.1	2.3	1.7	2.2	2.3	2.1	2.3	-2.3	-2.0	2.2
Trunk fat-free mass	1.9	10.6	23.5	-4.2	-3.3	-3.5	-1.5	-0.2	-3.6	1.4	-2.8	-3.0	-4.5	-2.7	-4.8	-2.6	4.1	3.3	-3.0
Falls in the last year	1.9	2.6	5.7	1.3	1.4	1.5	2.3	1.9	2.2	-1.5	1.6	1.6	0.9	1.1	1.6	1.2	-0.5	-1.7	2.4
Illnesses of mother	1.9	2.4	4.4	1.5	2.1	2.0	0.3	0.6	1.6	-1.2	1.5	1.9	1.5	1.6	1.9	1.7	-1.3	-1.4	1.3
Trunk predicted mass	1.9	10.8	23.5	-4.2	-3.4	-3.5	-1.6	-0.2	-3.6	1.5	-2.9	-3.1	-4.6	-2.7	-4.8	-2.6	4.1	3.3	-3.0
Alcohol intake frequency.	1.9	4.4	8.4	-1.8	-1.1	-1.1	-1.1	-2.5	-1.2	2.9	-2.6	-1.7	-2.6	-2.7	-0.2	-2.8	1.8	2.8	-2.1
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	6.3	-1.9	-2.2	-2.5	-1.3	-1.1	-2.0	0.4	-1.1	-1.3	-1.3	-0.8	-1.6	-0.8	1.8	0.6	-1.5
Hearing difficulty/problems: Yes	1.8	2.8	7.7	-1.7	-2.7	-2.8	-0.4	-0.7	-1.7	1.0	-1.6	-1.7	-1.6	-1.5	-2.0	-1.5	1.4	1.5	-1.2
Medication for hormone replacement therapy	1.8	2.1	6.4	-2.0	-2.0	-2.5	-1.8	0.6	-2.0	-0.6	-0.7	-1.9	-1.1	-0.3	-0.9	-0.2	1.9	0.5	-0.9
Vitamin and mineral supplements	1.8	2.4	4.5	1.9	1.6	2.0	0.6	0.5	1.9	-1.6	1.4	1.2	1.8	1.3	2.0	1.2	-1.3	-1.4	2.1
Impedance of arm (right)	1.8	8.3	19.5	4.3	3.6	3.1	2.2	1.0	3.6	1.1	1.6	3.7	3.7	0.9	4.4	0.8	-4.0	-1.8	1.5
Fasting Glucose	1.7	2.1	5.0	-2.2	-1.2	-2.0	-1.7	-0.6	-1.3	-0.4	-1.1	-1.1	-1.9	-0.8	-1.8	-0.6	2.2	1.2	-1.0
Blood clot in the leg (DVT)	1.7	2.2	4.0	-1.2	-0.8	-0.5	-2.0	-1.9	-0.7	1.4	-1.9	-1.4	-1.4	-1.9	-1.3	-1.9	1.7	1.7	-1.3
Commuting to job workplace: Cycle	1.7	2.1	4.1	1.8	1.8	1.8	0.6	0.2	1.9	-0.7	1.7	1.6	1.0	1.4	-0.1	1.5	-2.0	-1.2	1.8
Medication: Seretide 50 evohaler	1.6	1.9	4.1	1.6	2.0	1.1	-0.4	-0.6	2.0	-1.3	1.5	1.6	1.0	1.4	1.2	1.3	-1.0	-0.7	2.0
Supplements: Fish oil (including cod liver oil)	1.6	2.1	4.2	-1.3	-1.5	-0.2	-1.8	-1.5	-1.0	2.0	-1.5	-1.0	-1.7	-1.7	-0.1	-1.8	1.1	1.8	-1.6
Cholesterol lowering medication	1.6	2.3	8.1	-1.1	-1.8	-1.8	-2.8	-1.1	-1.6	0.8	-1.5	-2.3	-0.4	-1.4	-1.0	-1.3	1.2	0.6	-1.4
Alcohol drinker status: Previous	1.6	1.8	3.0	-1.3	-0.9	-1.2	-0.9	-0.9	-1.1	1.4	-1.5	-1.4	-1.7	-1.5	-1.5	-1.5	1.3	1.6	-1.2
Age when periods started (menarche)	1.5	3.5	7.1	2.2	2.1	2.7	1.3	0.6	2.3	-1.6	1.9	1.9	1.9	1.9	1.6	1.8	-1.6	-1.4	2.3
Noisy workplace	1.5	1.8	4.6	-1.6	-1.8	-1.4	-1.4	-0.7	-2.1	0.4	-1.3	-2.1	-1.1	-1.0	-1.6	-1.0	1.1	0.9	-1.1
Mouth/teeth dental problems: Loose teeth	1.5	1.7	5.0	-0.6	-1.3	0.5	-1.2	-2.2	-0.2	2.0	-1.5	-1.5	-0.8	-1.7	0.1	-1.8	0.5	1.4	-1.1
Supplements: Vitamin C	1.5	1.8	4.2	-1.5	-1.5	-1.5	-0.9	-0.1	-1.9	1.3	-1.5	-1.4	-1.0	-1.3	-1.3	-1.3	1.1	1.0	-2.1
Handedness (chirality/laterality): Left-handed	1.5	1.8	6.3	1.7	1.2	1.6	2.5	0.2	1.6	0.3	0.7	1.6	1.1	0.4	2.2	0.3	-1.4	-0.7	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.8	-1.0	-1.6	-1.0	-0.6	-0.3	-1.9	1.4	-1.3	-2.0	-0.6	-1.1	-1.7	-1.1	0.4	1.1	-1.7
Mineral and other dietary supplements	1.5	2.0	5.1	1.2	1.5	0.3	1.2	1.2	0.9	-2.2	1.5	1.0	1.6	1.9	0.6	1.9	-1.2	-1.6	1.7
Medication: Blood pressure	1.5	2.9	8.6	-1.7	-1.4	-2.9	-1.8	-0.0	-2.7	1.5	-1.4	-1.9	-1.0	-1.3	-1.2	-1.3	1.3	1.1	-2.4
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.0	1.0	1.6	-0.3	0.4	0.7	1.1	-1.5	1.7	1.3	1.4	1.7	1.0	1.7	-1.4	-1.7	1.6
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	5.5	-0.4	-0.3	-1.6	-0.2	-0.4	-0.7	2.3	-1.4	-0.8	-0.8	-1.9	-1.3	-1.9	0.4	1.4	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.4	5.7	-0.8	-1.1	-0.9	-1.2	-2.2	-0.7	2.4	-1.7	-1.3	-1.6	-2.0	-1.0	-2.0	0.5	2.0	-1.4
Hearing aid user	1.4	1.6	4.0	-1.6	-1.7	-2.0	0.0	-0.3	-1.2	0.9	-1.2	-0.8	-1.7	-1.1	-1.4	-1.2	1.2	1.3	-1.0
Alzheimer’s Disease (in mother)	1.3	1.5	4.5	0.6	0.5	0.0	1.2	1.1	0.9	-2.1	1.5	1.0	1.2	1.7	-0.0	1.7	-0.0	-1.8	1.4
Number of treatments/medications taken	1.3	2.4	6.7	-1.4	-1.3	-1.8	-2.6	-1.3	-1.4	1.2	-1.5	-1.5	-1.2	-1.6	-1.2	-1.5	1.7	1.2	-1.7
Systolic blood pressure, automated reading	1.3	3.7	6.7	-2.5	-1.9	-2.3	-0.6	-1.1	-2.6	1.7	-1.8	-2.6	-2.2	-1.8	-1.3	-1.7	1.9	1.6	-2.0
Depression (self-reported)	1.3	1.6	3.9	1.8	1.3	2.0	1.4	-0.2	1.7	-0.4	0.9	1.1	0.9	0.9	1.2	0.9	-1.9	-0.6	1.5
Medication for pain relief, constipation, heartburn	1.3	2.2	5.8	2.0	1.4	1.6	1.0	0.6	1.5	-0.5	1.3	1.1	1.8	1.3	1.6	1.3	-2.4	-1.4	1.4
Wears glasses or contact lenses	1.3	1.5	4.2	2.0	2.0	0.9	0.7	-0.1	2.0	0.0	0.8	1.2	1.2	0.4	1.0	0.5	-1.8	-0.5	1.3
Ever smoked	1.3	2.3	4.4	1.3	0.3	1.5	0.3	2.0	1.2	-2.0	1.6	0.7	1.7	1.7	1.6	1.7	-1.0	-2.1	1.9
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	3.1	-1.0	-0.7	-0.4	-1.8	-1.6	-0.5	1.1	-1.7	-1.2	-1.1	-1.7	-0.8	-1.7	1.6	1.3	-1.0
HbA1C	1.2	1.4	2.5	1.0	0.6	1.4	-0.4	1.6	0.7	-1.5	1.4	0.3	1.3	1.4	1.0	1.4	-0.9	-1.5	1.0
Number of live births	1.2	1.7	5.4	-1.7	-1.7	-1.6	-0.2	1.4	-2.3	0.0	-0.8	-1.2	-0.4	-0.4	-2.1	-0.4	1.2	-0.0	-1.7
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.5	1.7	1.5	1.5	-0.0	0.8	1.3	-1.7	2.1	1.8	1.9	2.0	1.6	2.1	-1.5	-1.9	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.8	-1.0	-1.0	-1.1	-0.1	-1.2	-1.2	1.2	-1.3	-1.9	-1.2	-1.3	-1.3	-1.2	0.9	1.5	-1.0
Medication: Paracetamol	1.2	2.0	3.7	-1.6	-1.3	-0.5	-0.5	-0.9	-0.8	1.4	-1.7	-1.2	-1.8	-1.9	-0.1	-1.9	1.8	1.9	-1.4
Body fat percentage	1.2	4.7	9.9	-2.7	-2.8	-2.8	-2.6	-1.2	-1.9	0.4	-1.6	-1.8	-2.5	-1.5	-3.1	-1.5	3.0	1.5	-1.6
Medication: Gliclazide	1.2	1.4	2.6	1.1	1.5	0.9	-0.1	0.8	1.2	-0.9	1.2	1.2	1.1	1.3	1.2	1.3	-1.6	-1.1	1.4
Number of operations (self-reported)	1.2	1.9	4.0	1.6	1.4	1.8	0.3	0.7	2.0	-1.1	1.5	1.2	1.3	1.3	1.0	1.3	-1.4	-1.2	1.7
Trunk fat percentage	1.1	4.4	8.8	-2.5	-2.6	-2.6	-2.6	-1.3	-1.7	0.8	-1.7	-1.6	-2.5	-1.7	-3.0	-1.7	2.8	1.7	-1.7
Allergy	1.1	2.4	5.2	1.1	1.0	1.7	1.6	1.3	0.9	-2.1	2.0	1.6	1.0	2.1	0.1	2.3	-1.1	-2.0	1.6
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.6	-1.3	-1.6	-1.2	-0.5	-1.2	-1.6	0.3	-0.9	-1.2	-1.1	-0.7	-1.4	-0.8	1.5	0.9	-0.8
Wheeze or whistling in the chest in last year	1.1	2.0	4.5	1.6	1.3	1.2	-0.2	0.2	1.7	-1.5	1.7	0.7	2.1	1.6	0.9	1.6	-1.4	-1.8	1.6
Suffer from ‘nerves’	1.1	1.8	3.8	1.1	0.9	1.0	0.5	0.6	1.1	-1.9	1.5	1.1	1.5	1.8	1.0	1.8	-0.8	-1.7	1.7
Mood swings	1.1	1.9	4.6	-1.4	-1.9	-2.1	-1.5	-0.9	-1.8	0.2	-1.0	-2.0	-0.9	-0.8	-2.1	-0.8	1.1	0.9	-1.2
Unable to work because of sickness or disability	1.1	1.4	2.8	-1.2	-1.7	-1.1	-1.1	-1.0	-1.2	1.4	-1.4	-1.0	-1.2	-1.3	-1.0	-1.2	0.5	1.4	-1.1
Bipolar Disorder (2018)	1.0	1.6	4.0	2.0	1.6	2.0	0.0	1.4	1.6	0.3	0.9	1.1	1.2	0.4	1.9	0.5	-1.3	-0.7	1.0
Alzheimer’s Disease (including proxy)	1.0	1.4	6.9	-0.6	-0.2	-0.9	-0.1	1.2	-0.2	-2.6	1.1	-0.1	0.6	1.4	-1.0	1.5	1.4	-1.6	1.1
Prostate Cancer	1.0	1.4	3.5	-1.5	-1.5	-1.2	-1.9	-1.3	-1.3	0.2	-1.0	-0.6	-1.1	-0.8	-0.3	-0.8	1.8	0.9	-1.1
Systolic Blood Pressure	1.0	5.1	11.8	-2.4	-2.0	-2.8	-0.7	-1.3	-3.4	2.7	-2.2	-2.9	-1.8	-2.2	-0.8	-2.2	1.8	1.9	-2.9
Smoking Status	1.0	2.3	7.7	0.3	0.1	1.2	-0.1	2.2	0.4	-2.8	1.6	0.7	0.9	1.9	2.0	1.9	-0.1	-2.1	1.7
Medication: Atenolol	1.0	1.3	3.2	-0.7	-0.8	-0.9	-1.8	-0.2	-0.7	1.6	-1.2	-0.6	-0.5	-1.4	-1.4	-1.5	0.9	1.0	-1.4
Lung cancer (father)	1.0	1.2	3.0	0.8	0.0	0.7	-0.3	1.7	0.5	-1.6	1.3	1.0	1.5	1.3	0.5	1.3	-0.2	-1.6	1.1
Medication: Allopurinol	1.0	1.4	2.5	-1.2	-1.6	-1.3	-1.3	-1.2	-1.1	0.8	-1.0	-1.3	-0.9	-1.0	-1.4	-1.1	1.3	1.0	-0.9
Age at last live birth	1.0	1.5	4.5	1.1	1.2	1.1	1.2	1.3	0.7	-0.7	1.1	0.9	1.7	1.2	2.1	1.2	-0.8	-1.5	0.7
Average weekly red wine intake	1.0	1.4	4.0	1.8	1.1	1.1	-0.2	0.9	1.6	0.3	0.7	1.7	1.6	0.3	2.0	0.4	-1.4	-0.8	0.6
Lupus	0.9	1.3	3.0	1.4	1.7	-0.9	-0.1	1.0	1.2	-0.7	1.2	0.7	1.1	1.1	-1.6	1.1	-1.7	-0.7	0.9
Supplements: Glucosamine	0.9	1.1	3.0	-0.4	-0.7	-0.3	0.0	-1.4	0.0	1.7	-1.0	-0.8	-1.3	-1.5	-1.4	-1.5	0.6	1.4	-0.7
Past tobacco smoking	0.9	1.7	5.2	-0.5	0.5	-0.9	-0.1	-2.0	-0.4	2.3	-1.3	-0.2	-1.3	-1.6	-1.0	-1.5	0.3	2.0	-1.5
Exposure to tobacco smoke at home	0.9	1.0	2.4	-0.8	-0.9	-0.9	-0.7	-1.2	-0.4	1.3	-1.1	-0.5	-1.6	-1.3	-0.7	-1.4	0.5	1.2	-0.8
Medication: Amlodipine	0.9	1.3	2.7	1.2	1.0	0.6	-1.0	0.9	0.7	-1.2	1.4	0.7	1.6	1.5	0.3	1.6	-1.1	-1.5	0.9
Leg fat percentage (right)	0.9	3.1	8.0	-2.3	-2.5	-2.3	-2.0	-1.0	-1.6	-0.5	-1.0	-1.5	-1.9	-0.8	-2.8	-0.8	2.7	1.0	-0.8
Medication: Blood pressure	0.9	1.6	6.1	-1.1	-1.2	-1.0	-2.5	-1.0	-1.2	1.3	-1.2	-1.1	-1.0	-1.2	-0.8	-1.3	0.9	1.1	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	4.6	-0.7	-1.0	-1.2	-2.1	-0.6	-1.3	0.5	-0.7	-1.3	-0.3	-0.5	-1.6	-0.5	0.7	0.4	-1.1
Bipolar Disorder or Schizophrenia	0.8	2.0	4.2	2.0	1.4	1.2	0.0	1.6	2.0	-0.4	1.4	1.8	1.5	1.0	1.4	1.0	-1.6	-1.0	1.3
Irritable Bowel Disease (IBD)	0.8	1.9	4.1	-1.7	-1.9	-1.8	-1.3	-0.2	-2.0	1.1	-1.2	-0.7	-2.0	-0.9	-1.4	-1.0	0.1	1.6	-1.4
Loud music exposure frequency	0.8	0.9	3.5	-1.0	-0.9	-1.8	-0.4	1.9	-1.5	-0.4	-0.1	-0.8	-0.4	0.0	-0.9	0.1	0.8	-0.5	-0.7
Glaucoma (self-reported)	0.8	1.0	3.2	1.2	1.2	0.4	-0.1	1.1	0.7	-0.6	1.0	0.9	1.8	1.0	1.0	0.9	-1.1	-1.3	0.6
Angina (self-reported)	0.8	1.0	3.7	1.9	1.4	1.1	-0.9	0.4	1.6	0.1	0.6	0.7	1.6	0.3	0.5	0.2	-1.3	-0.8	0.7
Smoking status: Previous	0.8	1.2	3.9	0.3	-0.4	0.8	-0.0	1.6	0.1	-2.0	1.1	-0.1	1.0	1.4	1.1	1.4	-0.5	-1.6	1.3
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.5	1.1	0.7	1.1	0.9	0.4	1.1	-1.3	1.3	0.8	1.6	1.3	1.1	1.2	-0.8	-1.5	1.5
Miserableness	0.8	1.3	2.5	1.0	0.9	-0.0	0.8	0.9	0.5	-1.2	1.5	1.2	1.2	1.6	-0.2	1.6	-1.6	-1.4	1.2
Leg fat percentage (left)	0.8	3.1	9.4	-2.3	-2.4	-2.4	-2.2	-0.8	-1.5	-1.0	-0.7	-1.3	-1.9	-0.4	-3.1	-0.4	2.6	0.8	-0.5
Age started oral contraceptive pill	0.8	1.0	1.8	-1.0	-0.1	-1.1	0.6	-0.9	-0.6	1.2	-1.1	-0.6	-1.4	-1.3	0.1	-1.2	0.9	1.2	-1.0
Myopia	0.8	1.2	3.5	-0.6	-0.7	-0.9	-0.2	-0.6	-0.5	1.9	-1.4	-1.3	-0.5	-1.6	-0.1	-1.5	0.6	1.3	-1.4
Supplements: Calcium	0.8	0.9	2.1	-1.0	-0.7	-0.1	0.7	-0.0	-0.4	1.5	-1.2	-0.6	-1.4	-1.4	-0.7	-1.3	0.9	1.2	-0.8
Heart disease (siblings)	0.8	1.0	2.6	0.9	1.0	1.2	-0.3	0.3	1.0	-0.9	0.9	1.4	1.6	0.9	1.1	1.0	-0.2	-1.5	0.7
Age at First Birth	0.7	1.0	4.1	-0.9	-0.4	-0.3	-0.3	-1.5	-0.2	0.9	-0.9	-0.8	-2.0	-1.0	-1.0	-0.9	0.2	1.7	-0.2
Blood Eosinophil Count	0.7	5.1	11.6	1.8	2.2	1.2	0.0	1.7	1.6	-2.6	2.9	2.0	2.8	3.0	1.7	3.0	-1.8	-3.4	1.9
Cardiovascular Disease	0.7	2.3	6.9	-1.9	-1.7	-2.4	-2.6	0.1	-2.4	0.4	-0.9	-1.8	-1.0	-0.7	-0.7	-0.7	1.4	0.4	-1.6
Lung FEV1/FVC ratio	0.7	3.6	11.0	-2.3	-3.3	-2.1	-1.0	-0.8	-3.0	0.6	-1.0	-1.9	-2.3	-0.7	-3.0	-0.7	1.6	1.4	-1.4
Tanning	0.7	9.1	14.1	3.3	2.9	2.7	2.5	2.7	2.8	-2.6	3.4	3.8	3.0	3.4	2.1	3.3	-3.2	-2.8	3.2
Average weekly spirits intake	0.7	0.9	2.5	0.1	-0.0	-0.6	-0.9	0.9	-0.1	1.3	-1.1	-1.6	-0.3	-1.5	-1.0	-1.5	0.4	0.9	-0.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.2	0.6	0.3	0.0	0.7	0.4	0.6	-1.3	1.3	1.2	0.7	1.4	0.1	1.5	-1.3	-0.7	1.2
Severe depression (siblings)	0.7	0.8	2.6	1.1	0.1	1.3	1.6	0.7	1.2	-0.6	0.9	0.5	0.4	0.6	0.3	0.6	-0.7	-0.4	1.4
Townsend deprivation index at recruitment	0.7	0.9	1.8	-1.2	-0.8	-0.6	-0.8	-0.6	-1.3	0.7	-1.1	-1.3	-0.8	-1.1	-0.8	-1.0	1.4	0.6	-1.0
Taking other prescription medications	0.7	1.1	3.6	-1.5	-1.2	-1.9	-1.3	-0.6	-1.3	-0.0	-0.7	-1.0	-1.2	-0.5	-1.0	-0.5	1.1	0.9	-0.8
Multivitamins +/- minerals	0.7	0.9	2.2	-1.5	-0.9	-1.3	-0.6	-0.0	-1.4	0.4	-0.5	-0.7	-1.5	-0.3	-1.1	-0.3	1.0	0.8	-1.2
Stomach or abdominal pain in last month	0.7	0.9	3.9	-0.2	-0.9	-1.1	-1.7	-1.3	-0.5	0.9	-0.5	-0.7	-0.5	-0.5	-2.0	-0.6	-0.4	0.9	-0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.7	1.2	1.2	0.6	2.2	0.9	1.1	-0.5	0.9	1.1	1.0	0.7	1.0	0.8	-0.9	-0.8	1.1
Gout (self-reported)	0.7	1.0	1.9	-0.9	-1.1	-0.9	-0.7	-0.5	-0.5	1.2	-0.9	-0.7	-1.2	-1.2	-0.9	-1.2	1.1	1.4	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.3	0.8	0.9	0.7	1.1	1.8	-0.0	-0.7	0.7	0.5	1.6	0.6	0.1	0.6	-0.5	-1.4	0.3
Number of full sisters	0.7	0.9	2.3	-1.3	-1.2	-0.9	-1.0	-0.9	-0.9	-0.1	-0.8	-1.5	-0.8	-0.6	-1.1	-0.6	1.4	0.3	-0.7
Eye problems/disorders: Glaucoma	0.7	0.8	2.4	1.1	1.1	0.4	-0.6	0.8	0.8	-0.6	0.8	0.8	1.6	0.9	0.6	0.8	-1.2	-1.0	0.5
Alzheimer’s Disease (in father)	0.6	0.6	1.8	0.3	0.9	0.5	-0.2	0.8	0.9	-1.3	0.8	0.7	0.6	0.9	-0.3	0.9	0.3	-0.9	1.3
Blood Red Count	0.6	5.9	12.5	-1.8	-1.7	-0.7	-2.2	-3.4	-1.4	3.2	-2.7	-2.1	-2.9	-2.8	-2.1	-2.9	1.2	3.5	-2.4
Angina	0.6	0.7	2.9	1.7	1.1	0.9	-1.0	0.4	1.3	0.5	0.3	0.5	1.4	-0.0	0.3	-0.1	-1.1	-0.5	0.3
Qualifications: CSEs or equivalent	0.6	0.8	3.1	-1.0	-0.6	-0.3	-0.3	-1.3	-0.8	-1.4	-0.2	-1.3	-0.5	0.2	-1.8	0.1	1.5	-0.1	0.3
Chronic bronchitis/emphysema (father)	0.6	0.7	2.1	1.4	0.5	1.3	0.6	0.2	1.4	-0.2	0.4	0.9	1.0	0.0	0.8	0.1	-0.7	-0.7	0.9
Alcohol usually taken with meals	0.6	0.9	3.7	1.2	1.0	1.1	0.0	1.0	1.1	0.1	0.6	1.9	0.9	0.5	0.7	0.6	-1.5	-0.5	0.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.1	1.3	1.4	0.9	1.1	0.6	0.7	0.2	0.6	0.4	0.8	0.4	0.4	0.3	-1.3	-1.0	0.5
Prospective memory result	0.6	0.7	1.7	-0.8	-0.7	-0.8	-0.3	0.4	-1.1	0.9	-0.8	-0.5	-1.3	-0.9	-0.7	-0.8	0.7	1.2	-1.0
High blood pressure (siblings)	0.6	0.9	2.2	-0.9	-0.6	-1.0	-1.4	-1.0	-0.8	0.9	-0.7	-0.8	-1.1	-0.8	-1.5	-0.7	0.5	0.9	-1.0
Heart disease (mother)	0.6	0.8	4.4	-0.0	-0.8	0.7	-2.0	-2.1	0.2	0.1	-0.1	-0.5	-0.0	-0.3	-1.4	-0.3	0.5	0.5	0.3
Leg pain on walking	0.6	0.7	1.5	-1.2	-1.0	-1.2	0.4	-0.1	-1.1	0.5	-0.7	-0.8	-1.1	-0.6	-0.6	-0.7	0.8	1.0	-0.9
Medication: Aspirin	0.6	0.8	1.7	-0.8	-0.8	-0.9	-1.3	0.3	-0.7	0.6	-0.9	-0.8	-1.0	-1.1	-0.9	-1.0	1.1	0.6	-1.1
Loneliness, isolation	0.6	0.8	3.0	-0.5	-0.5	-0.4	-0.5	-1.7	-0.1	1.0	-0.8	-0.5	-1.3	-0.8	-1.1	-0.9	-0.0	1.5	-0.3
Average weekly champagne plus white wine intake	0.6	0.8	2.5	0.3	0.5	-0.1	1.4	0.6	0.4	-1.6	1.1	1.0	0.7	1.3	0.1	1.3	-0.4	-0.8	1.0
High cholesterol (Self-reported)	0.6	1.1	4.4	-0.3	-0.9	-0.0	-1.6	-0.1	-0.7	-2.1	0.8	-0.6	1.2	1.2	-0.1	1.3	0.4	-1.7	0.6
Medication: Paracetamol	0.6	1.0	3.0	-0.7	-0.6	0.1	0.1	-1.2	0.1	1.2	-1.2	-0.4	-1.5	-1.4	-0.4	-1.5	0.7	1.7	-0.6
Medication: Atorvastatin	0.6	0.7	2.7	0.9	-0.2	-0.0	-0.7	1.2	-0.0	-1.0	0.7	0.0	1.7	0.9	-0.4	0.8	-0.8	-1.4	0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.3	-0.7	-1.1	-1.1	0.2	0.4	-0.5	1.1	-1.0	-0.5	-0.6	-1.1	-0.4	-1.0	0.7	0.5	-1.1
Ovarian Cancer	0.5	0.6	2.1	1.2	0.2	0.1	1.0	0.5	0.6	-0.2	0.8	1.3	0.8	0.8	-0.1	0.6	-1.4	-0.3	0.7
Schizophrenia (2014)	0.5	1.1	3.2	1.7	1.5	0.9	0.0	0.6	1.6	0.0	1.1	1.4	1.1	0.7	0.5	0.6	-1.8	0.0	0.0
Lung FVC	0.5	2.7	5.3	2.2	1.5	1.2	1.6	0.4	1.9	-1.3	1.7	1.7	1.8	1.7	-0.9	1.8	-2.2	-1.0	2.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.0	3.7	1.9	1.2	0.8	0.1	0.2	1.6	0.7	0.4	0.8	1.4	0.1	0.8	0.2	-1.9	-0.6	0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.0	0.3	-0.0	-0.7	-0.8	-1.2	0.3	1.4	-0.8	-0.1	-0.3	-1.2	0.1	-1.1	-0.3	0.9	-0.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	3.3	0.9	0.6	-0.3	-0.1	1.8	0.5	-0.1	0.7	0.9	1.1	0.5	0.0	0.5	-0.8	-0.9	0.2
Had other major operations	0.5	0.6	1.8	1.1	0.4	0.5	0.0	0.0	1.4	-0.5	0.8	0.6	0.9	0.6	-0.5	0.6	-1.2	-0.6	1.1
Emphysema/chronic bronchitis	0.5	0.5	1.4	1.0	0.5	0.8	-0.5	-0.6	0.9	-0.6	0.5	0.8	0.9	0.5	0.6	0.5	-1.2	-0.6	0.8
Medication: Ibuprofen	0.5	0.7	1.7	0.8	1.3	0.8	0.8	0.8	1.1	-0.7	0.9	0.6	0.7	0.6	-0.0	0.7	-0.5	-0.6	1.1
Overall health rating	0.5	1.0	3.2	-0.9	-0.9	-1.4	-1.8	-0.8	-1.2	1.0	-0.9	-1.1	-0.8	-0.8	-0.1	-0.8	0.3	0.7	-1.3
Ever had bowel cancer screening	0.5	0.6	2.5	0.9	1.3	1.2	0.1	0.3	1.6	0.6	0.1	1.0	-0.1	-0.3	-0.0	-0.2	-1.2	0.5	0.7
Ever taken oral contraceptive pill	0.5	0.5	2.3	-0.8	-0.5	-0.3	1.5	-0.3	-0.3	0.4	-0.6	-0.7	-1.1	-0.6	-1.0	-0.6	0.6	0.8	0.0
Vascular/heart problems diagnosed by doctor	0.5	1.4	4.1	1.2	1.0	1.8	2.0	0.0	1.9	-0.8	0.7	1.1	0.6	0.6	1.1	0.6	-0.7	-0.5	1.6
Pack years of smoking	0.5	0.8	3.0	1.0	1.4	1.3	0.3	-0.7	1.2	0.5	0.5	0.8	-0.5	0.2	0.9	0.3	-1.7	0.6	0.9
Schizophrenia (2018)	0.4	0.9	2.0	1.2	0.6	-0.1	0.0	1.1	1.3	-0.5	1.1	1.4	0.9	1.0	0.1	0.9	-1.4	-0.9	1.1
Body Mass Index (BMI) (2010)	0.4	0.6	9.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0
Ulcerative Colitis	0.4	0.6	2.6	-1.4	-1.2	-0.9	0.0	0.0	-1.2	0.2	-0.6	-0.1	-1.6	-0.4	-0.1	-0.4	0.8	0.0	0.0
Current tobacco smoking	0.4	0.6	3.3	0.1	0.3	1.1	0.6	1.8	0.5	-0.6	0.4	0.7	-0.1	0.3	1.6	0.3	0.0	-0.6	0.7
Serious illness, injury or assault to yourself	0.4	0.5	3.8	-0.7	-0.3	-0.4	0.5	-1.9	-0.2	0.4	-0.6	-0.4	-1.0	-0.3	-0.5	-0.4	-0.1	1.1	-0.2
Sitting height	0.4	3.0	11.6	-0.9	-0.6	-1.8	-0.3	0.9	-0.8	2.2	-1.8	-0.9	-1.9	-2.1	-3.4	-2.1	0.5	2.0	-1.9
Number of incorrect matches in round	0.4	0.7	3.3	0.5	0.6	-0.6	1.1	1.8	0.1	-0.4	0.5	0.7	1.1	0.5	1.0	0.7	-0.4	-1.2	0.3
Qualifications: None of the above	0.4	0.8	2.3	-0.8	-0.1	-0.0	-0.4	-0.6	-0.3	0.8	-1.3	-0.7	-1.2	-1.5	-0.2	-1.5	0.8	0.9	-0.7
Medication: Simvastatin	0.4	0.6	3.5	-0.2	-0.8	-0.5	-1.9	-1.3	-0.3	0.3	-0.5	-1.3	0.3	-0.5	-0.1	-0.4	0.3	-0.2	-0.3
Hair/balding pattern: Pattern 3	0.4	0.6	6.0	0.6	0.5	0.8	-0.3	-2.4	0.6	0.1	0.3	0.3	0.5	0.3	0.6	0.4	-0.4	-0.2	0.5
Pulse rate	0.4	0.7	2.3	-1.0	-0.9	-1.4	-0.1	0.5	-1.5	0.4	-0.6	-1.1	-0.4	-0.5	-0.6	-0.5	1.2	0.4	-1.0
Happiness	0.4	0.5	3.0	-0.3	-0.6	-0.8	0.6	1.7	-0.5	-1.0	0.8	0.4	-0.1	0.8	-0.6	0.8	0.2	-0.4	0.3
Mouth/teeth dental problems: Dentures	0.4	0.7	3.2	-1.0	-1.8	-0.7	-0.2	-0.4	-1.4	0.3	-0.9	-0.7	-0.5	-0.6	-1.0	-0.6	0.2	0.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.6	0.5	0.9	0.9	0.8	0.3	1.0	-0.2	0.8	0.5	0.7	0.6	1.3	0.6	-0.5	-0.7	0.7
Birth weight	0.4	0.9	3.3	0.2	0.5	1.8	1.8	0.0	1.4	-0.1	0.1	1.3	-1.2	-0.2	-0.2	-0.2	0.2	0.9	0.8
Migraine (self-reported)	0.4	0.5	1.6	-0.6	-0.5	-0.9	-0.4	1.3	-0.7	-0.3	-0.3	-0.7	-0.0	-0.2	-1.2	-0.3	1.1	-0.2	-0.5
Medication: Omeprazole	0.4	0.5	1.8	1.1	0.5	0.1	0.2	-0.1	1.0	-0.2	0.5	0.7	1.3	0.5	-0.2	0.5	-1.2	-0.8	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.1	0.7	0.4	1.1	0.2	0.2	1.0	-0.7	0.9	0.6	0.7	0.8	0.9	0.8	-0.4	-0.3	1.0
Illnesses of father: Heart disease	0.4	0.5	2.1	-0.1	0.4	1.5	-1.1	-0.7	0.2	-0.9	0.6	0.3	-0.4	0.7	1.0	0.6	0.4	0.0	0.7
Diabetes diagnosed by doctor	0.4	0.6	1.1	0.7	0.6	0.6	-0.9	1.0	0.6	-0.8	0.7	0.4	1.0	0.7	1.0	0.7	-0.6	-1.0	0.7
Medication: Aspirin	0.4	0.6	1.8	-0.4	-0.8	-0.7	-1.4	0.1	-0.5	0.6	-0.8	-0.6	-0.6	-0.9	-0.7	-0.8	0.8	0.5	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.3	0.7	0.2	-0.9	-0.3	0.5	0.3	-0.9	1.1	0.8	0.8	1.2	-1.5	1.3	-0.9	-0.7	1.2
Fractured/broken bones in last 5 years	0.4	0.5	2.8	-0.3	0.2	0.6	1.3	1.7	0.3	-0.2	-0.0	0.5	-0.4	-0.1	1.4	0.0	0.5	-0.3	0.1
Crohns Disease (2017)	0.3	0.7	3.0	-1.1	-1.2	-1.7	0.1	0.5	-1.4	0.2	-0.4	-0.4	-0.9	-0.2	-0.8	-0.3	-0.2	0.4	-0.7
Reaction Time	0.3	0.5	0.9	-0.8	-0.4	-0.9	-1.0	0.3	-0.7	0.9	-0.8	-0.9	-0.7	-0.7	0.4	-0.8	0.3	0.8	-0.9
Triglycerides	0.3	0.5	3.3	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	1.0	-1.8	0.0	0.0
Hypothyroidism (self reported)	0.3	0.7	6.4	-0.0	0.2	-0.8	0.4	0.5	-0.3	-0.4	0.3	-0.1	-0.1	0.7	-2.5	0.8	-1.4	0.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.6	0.3	0.6	0.4	-0.2	1.0	0.3	0.3	-0.0	0.7	-0.1	-0.2	1.6	-0.1	-0.1	-0.2	-0.2
Medication: Metformin	0.3	0.4	1.3	0.3	0.4	0.3	-0.7	1.1	0.1	-0.6	0.4	0.2	0.8	0.6	1.0	0.6	-0.4	-0.9	0.1
Diabetes (father)	0.3	0.4	2.0	-0.2	0.1	1.1	-1.4	-1.2	0.2	0.2	-0.2	-0.3	-0.3	-0.1	-0.8	-0.1	-0.3	0.4	-0.1
Pack years adult smoking proportion	0.3	0.5	1.3	0.4	0.8	1.0	-0.1	-1.1	0.5	1.0	-0.1	0.1	-0.8	-0.2	0.5	-0.2	-1.1	1.0	0.2
High blood pressure	0.3	0.9	3.1	-1.0	-0.7	-1.7	-1.6	0.4	-1.8	0.2	-0.3	-0.9	-0.2	-0.1	-1.0	-0.0	0.5	0.0	-1.2
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.1	-0.6	-0.6	-1.4	-0.6	-0.0	-0.5	1.2	-0.8	-0.5	-0.5	-1.0	0.6	-1.1	0.6	1.0	-0.9
Medication: Levothyroxine sodium	0.3	0.5	4.6	-0.2	0.0	-0.9	-0.5	-0.1	-0.5	0.4	-0.4	-0.7	-0.1	-0.3	-2.1	-0.3	-0.6	0.6	-0.5
Had menopause	0.3	0.4	0.9	0.1	0.5	-0.3	0.9	0.9	0.3	-0.8	0.8	0.9	0.4	0.8	0.1	0.8	-0.5	-0.5	0.5
Mouth/teeth dental problems	0.3	0.4	1.6	-0.7	-0.3	-1.0	-0.6	0.4	-0.8	0.2	-0.5	-0.5	-0.5	-0.5	-0.1	-0.4	1.2	0.4	-0.7
Diabetes (self-reported)	0.3	0.5	1.3	0.4	0.5	0.4	-1.0	0.6	0.5	-0.7	0.6	0.2	0.8	0.7	1.1	0.7	-0.4	-0.8	0.6
Medication: Ramipril	0.3	0.4	1.3	-0.9	-0.9	-1.1	-0.4	-0.2	-1.2	0.1	-0.3	-1.0	-0.6	-0.1	0.2	-0.2	0.5	0.1	-0.4
Worrier / anxious feelings	0.3	0.6	2.4	1.0	0.7	1.3	0.5	0.5	1.2	-0.0	0.6	0.7	0.4	0.4	1.6	0.5	-0.7	-0.1	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.8	0.3	0.8	0.5	0.7	0.5	0.6	-0.9	0.7	0.6	0.4	0.6	-0.5	0.6	0.1	-0.5	0.9
Medication: Cholesterol lowering	0.3	0.5	1.7	0.4	-0.3	0.6	-1.0	0.3	0.2	-1.0	0.7	-0.1	1.2	0.9	0.4	0.8	-0.2	-1.3	0.2
Peak expiratory flow (PEF)	0.3	0.7	4.2	1.5	0.7	1.0	0.3	-0.0	0.8	0.7	0.5	0.7	0.3	0.2	-0.4	0.3	-2.0	0.4	0.6
Worry too long after embarrassment	0.3	0.5	1.0	0.6	0.5	0.5	-1.0	-0.1	0.6	-1.0	0.7	-0.2	1.0	0.8	-0.3	0.8	-0.8	-0.4	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.7	1.0	0.5	0.7	1.0	-0.5	0.5	0.8	0.2	0.2	0.2	-0.0	-0.2	0.0	-1.6	0.4	0.5
Age at first live birth	0.3	0.6	1.3	0.9	1.1	0.1	1.0	1.2	0.5	-0.0	0.7	0.7	1.1	0.7	1.1	0.7	-0.8	-0.6	0.3
Health satisfaction	0.3	0.4	1.2	-0.8	-1.1	-1.0	-0.4	-0.6	-0.4	-0.7	0.1	-0.6	-0.8	0.2	-0.6	0.2	0.3	0.5	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.4	-0.0	0.0	1.6	1.0	0.7	0.8	-0.4	0.5	0.6	-0.7	0.2	-0.1	0.1	0.2	0.2	0.5
Knee pain experienced in last month	0.3	0.4	1.8	-0.4	-0.5	0.1	0.5	-0.4	-0.4	0.5	-0.3	-0.6	-1.1	-0.5	-1.3	-0.5	0.5	1.0	-0.1
Hypertension (Self-reported)	0.3	0.8	3.1	-0.9	-0.8	-1.6	-1.8	0.1	-1.5	0.5	-0.4	-0.9	-0.2	-0.2	-0.7	-0.2	0.5	0.2	-1.2
Qualifications: nursing, teaching	0.3	0.5	1.0	1.0	0.3	0.0	-0.2	0.2	0.7	-0.4	0.8	0.9	1.0	0.8	0.7	0.8	-0.9	-0.6	0.7
Commuting to job workplace: Walk	0.3	0.3	1.9	-0.2	0.3	0.2	0.8	1.4	-0.1	-0.7	0.4	0.3	0.2	0.3	0.8	0.3	0.6	-0.8	0.3
Illnesses of father: None of the above (group 1)	0.3	0.4	1.3	-0.3	-1.0	-1.1	0.6	0.9	-0.7	0.7	-0.4	-0.3	-0.4	-0.5	-0.5	-0.4	-0.2	0.6	-0.7
Commuting to job workplace: Public transport	0.3	0.3	0.7	0.6	0.6	0.4	0.1	0.8	0.7	-0.7	0.5	-0.0	0.6	0.4	0.5	0.5	-0.2	-0.8	0.8
Alcohol drinker status: Never	0.3	0.4	1.7	0.5	0.7	0.8	-0.1	-1.3	0.9	0.5	-0.0	0.2	0.2	-0.1	1.3	-0.1	-0.4	0.1	0.2
Diastolic blood pressure, automated reading	0.3	0.9	2.5	-1.5	-0.5	-1.1	-0.5	0.4	-1.4	-1.6	0.8	-0.6	-0.9	1.2	-0.1	1.3	0.8	-0.5	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.2	0.6	0.3	-0.3	-0.2	-0.2	0.8	-0.5	0.4	0.3	1.1	0.4	-1.0	0.5	-0.6	-0.8	0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	0.9	0.9	1.2	-0.2	-0.2	0.8	0.4	0.1	0.2	0.8	0.0	0.9	0.0	-0.8	-0.5	0.1
Depressed Affect (Nagel 2018)	0.2	0.5	2.5	0.2	-0.7	-0.8	-0.9	-1.3	0.1	0.5	-0.2	-0.4	-0.1	-0.3	-1.6	-0.4	-0.3	0.6	-0.1
Depression (Nagel 2018)	0.2	0.3	0.9	0.9	0.5	0.2	0.6	-0.5	0.9	0.2	0.5	0.3	0.6	0.3	-0.1	0.0	-0.7	-0.4	0.6
Neuroticism (2016)	0.2	0.3	2.0	0.4	-0.1	0.2	-1.4	-1.3	0.1	0.1	0.1	-0.5	-0.4	-0.1	-0.0	-0.2	-0.1	0.3	0.3
Primary Biliary Cirrhosis	0.2	0.3	3.2	0.1	0.3	-0.7	-0.8	-0.2	0.4	-0.3	-0.0	-0.6	-0.2	-0.1	-1.8	-0.1	0.0	0.2	0.6
Rheumatoid Arthritis	0.2	0.3	0.9	-0.2	-0.3	-0.4	0.0	0.2	-0.2	0.6	-0.6	-0.1	-0.6	-0.6	-1.0	-0.6	0.0	0.6	-0.7
Blood White Count	0.2	1.4	8.0	-0.5	-0.2	-0.5	-2.8	-2.3	-0.2	1.2	-1.0	-1.3	-0.6	-1.1	-0.4	-1.1	0.2	1.0	-0.6
Height	0.2	3.0	10.8	2.0	3.0	0.8	2.1	2.9	2.2	0.6	0.8	3.3	1.3	0.1	-0.4	0.0	-1.7	-0.8	0.5
Allergy or Eczema	0.2	0.6	3.6	-0.9	-0.7	-1.9	-1.4	0.3	-0.8	0.1	-0.3	-0.7	-0.2	-0.3	0.2	-0.5	0.7	0.4	-0.5
Respiratory disease	0.2	0.4	1.1	0.7	0.6	1.1	-0.7	-0.9	0.7	0.0	0.4	-0.2	0.7	0.3	0.8	0.2	-0.9	0.1	0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.8	-0.4	-0.4	0.0	-1.3	1.2	-0.3	-0.2	-0.2	-0.3	-0.0	-0.1	0.9	-0.1	0.3	-0.2	-0.2
Neuroticism	0.2	0.4	2.2	-0.1	-0.7	-0.8	-1.5	-1.2	-0.0	0.2	-0.3	-0.9	0.1	-0.4	-1.0	-0.3	0.3	0.4	-0.0
Hand grip strength (left)	0.2	0.4	2.5	0.2	0.2	0.1	1.1	1.3	0.3	-0.5	0.3	1.0	-0.3	0.2	-1.6	0.2	0.2	0.1	0.1
Sensitivity / hurt feelings	0.2	0.4	2.2	0.2	-0.3	0.6	-1.5	-1.0	0.6	-1.0	0.4	-0.1	0.7	0.6	-0.3	0.5	-0.1	-0.4	0.6
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.5	0.2	0.2	-0.3	0.6	-1.6	0.4	0.8	-0.2	-0.1	-0.2	-0.2	-0.0	-0.3	-0.6	0.4	-0.0
Diabetes (mother)	0.2	0.3	1.0	0.7	0.0	0.6	-0.0	0.6	0.5	-0.4	0.5	0.3	0.6	0.6	0.8	0.5	-1.0	-0.5	0.3
Hand grip strength (right)	0.2	0.7	2.2	0.5	1.0	0.4	1.1	0.7	0.6	-1.0	0.8	1.2	0.2	0.8	-1.5	0.8	-0.3	-0.5	0.7
Fed-up feelings	0.2	0.5	3.2	0.4	-0.4	-0.5	-1.5	-1.8	0.1	0.3	-0.2	-0.0	0.3	-0.2	-0.8	-0.2	-0.2	0.1	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.2	-0.1	0.2	0.1	-1.1	0.2	0.9	-0.5	-0.6	-0.6	-0.7	0.0	-0.7	0.3	0.8	-0.1
Forced vital capacity (FVC)	0.2	0.9	3.1	1.4	0.9	0.3	0.9	0.9	1.1	-0.0	0.7	1.0	0.7	0.5	-1.3	0.7	-1.8	-0.0	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.0	1.1	0.5	0.2	-0.6	-0.4	0.9	1.4	-0.5	-0.0	0.6	-0.8	-0.1	-0.8	-0.9	0.3	-0.4
Financial difficulties in last 2 years	0.2	0.3	0.7	0.5	0.4	0.5	0.5	-0.3	0.3	-0.5	0.7	-0.4	0.6	0.7	0.6	0.5	-0.5	-0.5	0.8
Heart attack	0.2	0.3	0.9	0.6	0.7	0.9	-0.4	-0.3	0.6	0.5	-0.1	-0.1	0.5	-0.2	0.8	-0.2	-0.5	-0.3	-0.1
Pain all over the body in last month	0.2	0.2	1.4	-0.4	-0.7	-0.3	0.3	1.2	-0.1	-0.5	-0.1	0.1	-0.4	-0.0	-0.2	0.0	0.2	-0.0	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.1	-0.1	-0.7	-1.1	-0.6	-0.5	-0.2	-0.0	0.0	0.2	0.1	0.0	0.9	-0.0	0.2	0.0	-0.2
Illnesses of siblings	0.2	0.3	1.2	0.5	0.6	0.3	1.1	1.1	0.5	-0.3	0.4	0.2	0.4	0.3	0.9	0.3	-0.4	-0.3	0.5
Father’s age at death	0.2	0.3	0.8	-0.6	0.0	-0.4	-0.0	0.2	-0.4	0.9	-0.5	0.1	-0.4	-0.7	0.6	-0.7	0.9	0.6	-0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	6.7	0.2	-0.7	-0.8	0.3	-0.2	-0.4	0.6	-0.1	-0.2	-0.4	-0.1	-2.6	-0.0	-0.9	0.9	0.2
Hair/balding pattern: Pattern 4	0.2	0.6	3.3	0.4	0.9	0.3	1.8	1.5	0.7	0.6	-0.3	0.5	-0.2	-0.5	-0.6	-0.5	-0.5	0.4	-0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	0.2	0.2	-0.8	-0.5	0.4	-0.2	-0.4	0.8	-0.0	-0.1	0.9	0.4	0.9	-0.9	-0.2	0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.8	0.2	0.7	-0.5	0.7	1.1	0.2	-0.3	0.3	0.0	0.1	0.4	-1.7	0.5	-1.1	0.1	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	-0.5	-0.7	-0.8	0.3	0.1	-0.8	-0.0	-0.1	-0.5	-0.8	-0.0	-0.8	-0.0	-0.2	0.6	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.8	1.6	1.2	1.1	0.4	1.0	0.9	1.0	-0.4	0.9	1.2	0.8	0.7	-0.3	0.8	-1.2	-0.2	1.2
Shortness of breath walking on level ground	0.2	0.3	1.7	-0.4	-0.7	-1.3	0.0	-0.2	-0.3	0.4	-0.2	-0.2	-0.6	-0.2	-0.2	-0.3	-0.4	0.7	-0.2
Qualifications: College or University degree	0.2	0.6	2.4	1.4	0.5	0.6	0.4	0.7	0.9	0.5	0.6	0.8	1.2	0.4	0.9	0.4	-1.5	-0.4	0.3
Mean time to correctly identify matches	0.2	0.3	1.3	0.2	0.3	-0.3	-0.6	0.4	0.3	1.1	-0.5	-0.4	-0.0	-0.7	1.0	-0.7	-0.6	0.5	-0.3
Comparative height size at age 10	0.2	0.9	4.8	0.4	1.3	0.1	1.5	2.2	0.8	0.0	0.5	1.5	-0.4	0.2	1.0	0.3	-0.5	-0.2	0.3
Family relationship satisfaction	0.2	0.2	1.0	0.4	0.0	0.7	0.6	0.0	0.4	0.2	0.4	0.6	-0.1	0.2	1.0	0.2	-0.2	0.2	0.3
Long-standing illness, disability or infirmity	0.2	0.3	0.8	-0.9	-0.3	-0.8	-0.1	0.4	-0.6	-0.6	0.3	-0.4	-0.8	0.6	-0.0	0.6	-0.0	0.2	0.1
Osteoarthritis (self-reported)	0.2	0.3	1.8	-0.4	-1.1	-0.4	1.4	0.7	-0.2	-0.1	0.2	0.1	-0.6	0.0	-0.7	0.0	0.2	0.2	0.4
Smoking status: Current	0.2	0.3	2.3	-0.2	-0.0	0.7	0.4	1.5	0.2	-0.2	0.1	0.4	-0.3	0.0	1.1	0.0	0.3	-0.3	0.2
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.3	-0.1	-0.2	-1.1	-0.4	-0.2	-0.6	0.2	0.1	0.5	0.2	0.1	-0.5	0.2	-0.2	-0.0	-0.4
Illnesses of father: High blood pressure	0.2	0.2	0.9	0.5	0.7	-0.3	-0.9	-0.8	0.1	0.3	0.2	-0.0	0.6	0.1	0.4	-0.0	-0.2	-0.4	-0.2
Pain experienced in last month	0.2	0.3	1.2	0.6	0.3	0.2	-0.3	-0.8	0.4	-0.0	0.2	0.2	1.1	0.3	1.1	0.2	-0.4	-0.7	0.1
Neuroticism (Nagel 2018)	0.1	0.3	1.5	0.2	-0.5	-0.3	-0.8	-1.2	0.3	0.1	0.0	-0.4	0.4	-0.0	-1.2	-0.1	-0.1	0.1	0.1
Worry (Nagel 2018)	0.1	0.1	0.6	0.2	0.1	0.1	0.8	-0.3	0.4	-0.3	0.4	0.1	0.3	0.4	0.2	0.4	-0.1	-0.2	0.4
Heel T-Score	0.1	0.5	2.1	0.8	0.1	0.8	-0.8	-1.3	0.2	0.5	0.4	-0.6	0.7	0.3	-0.5	0.2	-1.4	-0.2	0.5
Chronotype (morning person)	0.1	0.3	1.2	0.3	0.4	-0.0	-0.4	-0.1	-0.4	1.1	-0.2	-0.3	0.0	-0.4	-0.7	-0.3	-1.0	0.2	-0.7
Average weekly fortified wine intake	0.1	0.1	0.7	0.4	0.2	-0.4	0.6	0.2	0.0	0.3	0.1	0.1	0.9	0.0	-0.4	0.1	-0.5	-0.3	-0.1
Maternal smoking around birth	0.1	0.2	0.7	-0.4	-0.5	-0.9	-0.3	0.3	-0.7	-0.7	0.3	-0.5	0.1	0.4	-0.3	0.4	0.2	-0.4	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	1.1	-0.3	-0.0	-0.5	0.3	-1.0	0.1	0.0	-0.4	-0.1	-0.4	-0.3	-0.8	-0.3	0.5	0.3	0.1
Nervous feelings	0.1	0.2	0.6	0.2	0.8	0.6	0.0	-0.2	0.5	-0.4	0.3	-0.1	0.6	0.3	0.2	0.4	0.1	-0.6	0.4
Neuroticism score	0.1	0.2	0.4	0.5	0.0	-0.3	-0.5	-0.7	0.5	-0.1	0.3	-0.2	0.6	0.2	-0.6	0.3	-0.5	-0.1	0.3
Time employed in main current job	0.1	0.1	0.9	0.1	-0.1	-0.6	0.0	-0.9	-0.2	0.5	-0.3	-0.0	0.2	-0.2	-0.5	-0.2	-0.3	0.1	-0.4
Alcohol intake versus 10 years previously	0.1	0.2	0.8	-0.1	-0.1	-0.1	0.8	0.9	-0.8	0.0	0.1	-0.6	0.6	0.3	0.3	0.2	-0.4	-0.5	0.0
Asthma	0.1	0.2	0.7	-0.4	-0.1	-0.5	-0.5	-0.7	-0.2	0.3	-0.4	-0.8	0.0	-0.4	0.5	-0.4	0.3	0.5	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	2.1	0.5	-0.1	-0.2	0.6	-0.2	-0.1	0.2	0.3	0.3	-0.0	0.2	-1.4	0.3	-0.8	0.5	0.6
Standing height	0.1	1.0	4.8	0.8	1.8	0.3	1.3	2.2	1.1	0.9	0.0	1.7	-0.1	-0.5	-0.4	-0.4	-0.6	0.1	-0.2
Tense / ‘highly strung’	0.1	0.2	1.1	-0.8	-0.3	-0.5	-0.6	-0.5	-0.5	-0.3	-0.2	-0.3	-0.5	-0.0	-0.5	0.0	1.0	0.1	-0.5
Birth weight of first child	0.1	0.1	0.5	0.1	0.3	-0.1	0.2	0.1	0.6	-0.7	0.3	0.7	-0.4	0.3	-0.4	0.3	-0.1	0.0	0.5
Headache pain in last month	0.1	0.3	1.4	0.2	1.2	-0.3	0.3	1.1	0.6	0.1	0.1	0.2	-0.6	-0.1	-0.5	-0.1	-0.1	0.5	0.0
Number of full brothers	0.1	0.1	0.7	-0.1	-0.2	0.2	-0.0	-0.1	-0.1	-0.6	0.0	-0.2	0.3	-0.0	-0.7	0.1	0.8	-0.7	0.1
Neck or shoulder pain in last month	0.1	0.2	1.1	0.3	0.4	1.1	0.1	-0.1	0.6	0.4	-0.0	0.3	-0.0	-0.3	0.5	-0.3	0.1	0.2	0.3
Pulse rate, automated reading	0.1	0.4	1.3	0.2	0.3	0.0	1.1	0.8	0.0	-0.8	0.7	0.4	0.4	0.8	0.6	0.8	-0.6	-0.4	0.6
Had major operations	0.1	0.1	0.4	-0.2	0.2	0.5	-0.4	0.3	0.5	-0.5	0.3	0.4	-0.1	0.3	0.3	0.3	0.6	-0.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.6	0.1	-0.0	-0.5	-0.6	0.8	-0.4	0.2	0.0	0.2	0.4	0.1	0.4	0.2	-0.3	-0.4	-0.8
Illnesses of siblings: Diabetes	0.1	0.1	0.6	0.2	-0.0	0.6	0.1	0.5	0.8	-0.4	0.2	0.4	-0.2	0.1	-0.3	0.2	0.1	0.2	0.3
Friendships satisfaction	0.1	0.2	0.8	0.4	-0.1	-0.1	-0.3	0.7	0.1	0.3	0.4	0.3	-0.0	0.3	0.9	0.1	-0.6	0.3	0.1
Asthma (self-reported)	0.1	0.1	1.1	-0.0	0.4	0.1	-0.2	-0.3	0.3	0.1	0.0	-0.3	0.4	0.0	1.1	-0.1	-0.0	0.2	0.1
Number of self-reported non-cancer illnesses	0.1	0.2	1.3	0.0	-0.4	-1.0	-1.1	0.1	-0.1	0.6	-0.1	-0.2	-0.1	-0.3	-0.2	-0.3	-0.4	0.3	-0.3
Guilty feelings	0.1	0.1	0.5	0.0	0.1	0.2	0.1	0.2	0.2	-0.3	0.3	-0.2	0.2	0.1	-0.7	0.1	0.6	-0.4	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.7	0.3	0.4	-0.0	-0.8	0.3	0.2	0.3	-0.0	-0.0	0.3	-0.2	0.8	-0.1	0.1	-0.1	-0.4
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.3	0.0	0.0	-0.4	0.0	0.0	-0.5	0.0	0.0	-0.2	0.0	0.0	-0.2	0.0	0.2	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.2	0.1	0.0	0.0
LDL Cholesterol	0.0	0.0	0.4	-0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.7	-0.3	0.2	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.6	2.0	-0.1	-0.0	-0.3	0.6	1.4	-0.2	-1.2	0.9	0.3	0.1	1.1	-0.7	1.1	-0.6	-0.7	0.9
Financial situation satisfaction	0.0	0.1	0.3	0.2	-0.1	0.1	-0.3	-0.3	-0.1	0.5	0.3	-0.4	-0.0	0.1	-0.3	0.1	-0.4	0.1	0.2

Hub : Genes

POLR2L

Models

Trait associations