TWAS hub - PNPLA2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2310	0.0420	0.0e+00	0.232	0.176	0.220	0.225	0.225	7.7e-28	6.6e-21	2.5e-26	6.3e-27	6.0e-27
2	GTEx	Artery Tibial	0.0949	0.0360	3.0e-03	0.114	NA	0.071	NA	0.106	3.2e-09	NA	3.4e-06	NA	1.2e-08
3	GTEx	Brain Cerebellum	0.2530	0.1110	5.4e-03	0.251	NA	0.188	NA	0.224	4.9e-08	NA	3.1e-06	NA	3.1e-07
4	GTEx	Brain Cortex	0.3080	0.0860	1.6e-04	0.379	NA	0.331	NA	0.332	1.9e-11	NA	6.4e-10	NA	5.8e-10
5	GTEx	Brain Hypothalamus	0.2330	0.0990	5.2e-03	-0.007	NA	-0.011	NA	-0.003	4.9e-01	NA	7.4e-01	NA	3.9e-01
6	GTEx	Heart Left Ventricle	0.3185	0.0714	7.9e-07	0.179	NA	0.197	NA	0.188	7.7e-10	NA	9.4e-11	NA	2.8e-10
7	ROSMAP	Brain Pre-frontal Cortex	0.5741	0.0445	0.0e+00	0.431	0.437	0.513	0.491	0.525	1.4e-60	1.2e-61	9.1e-77	3.6e-72	3.0e-79
8	YFS	Blood	0.1051	0.0219	0.0e+00	0.103	0.090	0.121	0.118	0.125	6.1e-32	5.6e-28	1.4e-37	1.5e-36	1.2e-38
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0673	0.0320	6.8e-04	0.004	0.032	0.021	NA	0.006	1.2e-01	1.4e-04	1.6e-03	NA	5.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Breast Cancer	13.1	31.5	44.9	6.4	5.0	6.0	5.9	6.1	4.1	6.7	6.2	-3.0
Waist Hip Ratio (WHR)	5.3	24.0	65.1	4.0	4.0	3.0	3.1	8.1	3.6	5.1	5.9	-5.2
Impedance of leg (left)	5.2	25.1	51.9	4.8	3.5	3.8	4.0	7.2	1.3	5.4	5.4	-6.9
Osteoporosis (self-reported)	5.2	6.4	10.9	2.9	2.3	2.6	2.7	3.3	1.1	3.0	2.7	-1.3
Impedance of leg (right)	4.7	22.7	48.6	4.6	3.1	3.7	3.7	7.0	0.9	5.1	5.2	-6.7
Medication: Lisinopril	4.1	5.4	27.8	-1.2	-0.1	-0.6	-0.6	-3.6	-0.6	-1.6	-1.4	5.3
Breast cancer (self-reported)	4.0	4.8	8.8	-2.1	-1.3	-1.8	-1.8	-3.0	-1.0	-2.7	-2.4	2.6
Medication: Atorvastatin	3.7	4.6	6.3	2.5	1.9	2.4	2.3	2.4	1.4	2.4	2.5	-0.9
Medication: Cholesterol lowering	3.6	5.6	10.6	2.8	1.3	2.6	2.5	2.6	1.9	3.3	2.4	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.6	4.2	6.2	2.4	1.2	2.1	2.2	2.3	0.7	2.5	1.9	-2.5
Impedance of whole body	3.6	18.2	47.1	3.6	2.4	2.7	2.7	6.9	0.8	4.5	4.7	-6.4
Loneliness, isolation	3.5	4.8	7.6	-2.7	-1.7	-2.8	-2.7	-1.4	-2.0	-2.5	-2.3	0.8
Serious illness, injury or assault to yourself	3.4	4.1	6.9	-2.4	-1.6	-2.5	-2.4	-1.8	-0.8	-2.6	-2.3	0.6
Comparative body size at age 10	3.4	9.3	14.1	-3.3	-2.4	-3.0	-2.9	-3.8	-0.9	-3.4	-3.2	3.6
Pulse wave Arterial Stiffness index	3.2	3.7	9.8	2.1	0.7	1.6	1.7	2.5	0.7	2.1	1.6	-3.1
Breastfed as a baby	3.2	4.0	5.9	2.2	2.2	2.4	2.4	1.2	1.9	2.2	2.1	0.1
BMI	3.1	17.8	40.2	-4.0	-2.7	-3.3	-3.4	-6.3	-0.8	-4.6	-4.6	5.6
Heart disease (siblings)	3.0	3.7	6.1	2.4	1.3	2.5	2.4	0.6	2.3	1.9	1.9	-1.2
Angina (self-reported)	2.9	3.8	5.3	2.2	2.0	2.0	2.1	2.1	1.6	2.1	2.3	-0.8
Pulse wave peak to peak time	2.8	3.3	9.8	-2.0	-0.5	-1.5	-1.6	-2.2	-0.6	-1.9	-1.4	3.1
Medication: Omeprazole (e.g. Zanprol)	2.6	3.2	7.1	1.8	0.8	1.6	1.6	2.7	0.5	2.5	1.9	-1.5
Age at First Birth	2.5	3.6	5.0	-2.2	-1.5	-2.2	-2.1	-1.6	-2.0	-2.1	-2.2	0.0
Angina	2.5	3.3	4.6	2.0	1.9	2.0	2.0	1.7	1.6	1.9	2.1	-0.5
High blood pressure (mother)	2.5	3.4	6.4	-1.9	-1.1	-1.6	-1.6	-2.5	-1.4	-2.1	-2.0	2.0
Eye problems/disorders: Glaucoma	2.5	2.9	4.3	2.0	1.6	2.1	2.1	1.3	1.3	2.0	1.9	-0.6
Ever depressed for a whole week	2.5	3.1	7.3	1.7	0.9	1.4	1.4	2.3	1.0	1.9	1.7	-2.7
Eye problems/disorders: None of the above	2.4	2.8	5.8	-1.4	-1.8	-1.0	-1.2	-2.4	-1.7	-1.8	-1.8	1.4
Ulcerative Colitis (UC)	2.3	4.3	17.0	-1.5	0.0	-1.2	-1.1	-3.2	-0.5	-1.9	-1.7	4.1
Leg fat-free mass (left)	2.3	12.4	35.7	-3.0	-2.0	-2.1	-2.1	-5.3	-0.0	-3.7	-3.5	6.0
Leg predicted mass (left)	2.3	12.4	35.5	-3.1	-1.9	-2.1	-2.1	-5.3	0.0	-3.7	-3.5	6.0
Hip circumference	2.3	10.0	31.5	-2.5	-1.5	-1.7	-1.7	-5.6	0.7	-3.1	-3.3	4.8
Lung cancer (father)	2.3	2.7	5.2	2.2	1.2	2.3	2.2	0.8	1.2	1.7	1.6	-1.0
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	4.3	1.8	1.9	2.1	2.0	0.9	1.3	1.6	1.9	0.9
Leg fat-free mass (right)	2.3	12.3	36.1	-3.0	-1.9	-2.1	-2.1	-5.2	0.2	-3.6	-3.5	6.0
Leg predicted mass (right)	2.3	12.1	36.2	-3.0	-1.8	-2.1	-2.1	-5.2	0.2	-3.6	-3.5	6.0
Medication: Metformin	2.2	3.2	4.8	1.8	2.0	1.8	1.8	1.8	1.4	2.2	2.2	-0.2
Body mass index (BMI)	2.2	9.4	27.0	-2.4	-2.1	-1.7	-1.9	-5.2	0.0	-3.0	-3.5	4.4
Number of incorrect matches in round	2.2	3.7	5.3	2.0	1.7	2.2	2.2	1.7	2.2	2.0	2.3	-0.7
Supplements: Glucosamine	2.1	2.7	6.0	-1.5	-2.5	-1.3	-1.4	-1.3	-1.9	-1.8	-2.1	-0.1
Length of working week for main job	2.1	2.3	6.5	-1.2	-2.2	-1.0	-1.1	-1.1	-2.6	-1.2	-1.7	0.2
Medication: Omeprazole	2.0	2.3	7.2	1.3	0.7	1.0	0.9	2.7	0.5	2.1	1.5	-1.8
Fasting Glucose	1.9	2.3	5.5	-1.6	-1.2	-1.4	-1.3	-2.3	0.0	-1.8	-1.6	1.4
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	3.2	1.7	1.7	1.7	1.7	1.5	0.5	1.6	1.8	0.4
Ever highly irritable/argumentative for 2 days	1.9	2.2	3.3	-1.7	-1.4	-1.7	-1.8	-1.3	-1.4	-1.4	-1.8	0.6
Ever taken oral contraceptive pill	1.9	2.1	2.8	-1.6	-1.7	-1.5	-1.5	-1.6	-1.2	-1.6	-1.6	0.2
Alcohol intake frequency.	1.8	4.2	7.0	-2.3	-1.9	-2.1	-2.1	-1.9	-1.5	-2.7	-2.2	1.5
Average weekly red wine intake	1.8	2.7	5.1	2.0	1.7	2.2	2.2	0.5	1.4	1.5	1.7	-0.4
Knee pain experienced in last month	1.7	2.7	4.0	-2.0	-1.7	-2.0	-1.9	-1.6	-0.4	-1.7	-1.9	0.6
Whole body water mass	1.7	9.5	31.1	-2.4	-1.1	-1.5	-1.5	-4.9	0.5	-3.2	-2.9	5.6
Financial situation satisfaction	1.7	2.1	4.7	-1.8	-1.6	-2.1	-2.2	-0.2	-1.3	-1.0	-1.2	-0.5
Basal metabolic rate	1.7	9.5	30.2	-2.4	-1.3	-1.5	-1.5	-5.0	0.6	-3.1	-3.0	5.5
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	3.6	-1.1	-1.3	-1.0	-0.9	-1.9	-1.4	-1.4	-1.6	1.3
Impedance of arm (left)	1.6	7.5	25.6	1.7	1.1	1.1	1.1	5.1	0.2	2.6	3.0	-4.4
Arm fat mass (right)	1.6	6.4	18.4	-1.9	-1.7	-1.2	-1.3	-4.3	0.5	-2.3	-2.8	4.0
Gout (self-reported)	1.6	2.2	5.3	-1.4	-1.1	-1.2	-1.2	-2.3	-1.3	-1.6	-1.6	1.1
Whole body fat-free mass	1.6	9.4	30.6	-2.4	-1.1	-1.6	-1.5	-4.9	0.5	-3.1	-2.9	5.5
Alcohol drinker status: Previous	1.6	1.9	4.0	-1.2	-1.3	-0.9	-1.0	-2.0	-1.1	-1.4	-1.6	1.5
Blood Platelet Count	1.5	16.9	27.9	-4.3	-5.3	-3.8	-3.9	-3.6	-3.5	-3.7	-4.8	3.8
Diabetes (mother)	1.5	2.0	6.0	0.9	2.4	0.8	0.9	1.2	1.7	1.2	1.9	0.3
Hair/balding pattern: Pattern 2	1.5	1.9	8.2	0.7	2.9	0.8	0.9	-0.7	2.0	0.4	1.1	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	4.8	-1.8	-1.5	-1.9	-1.8	0.2	-2.2	-1.4	-1.5	0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	2.8	1.4	1.0	1.4	1.5	0.9	1.7	1.2	1.5	-1.0
Diabetes diagnosed by doctor	1.5	2.5	4.9	1.5	1.2	1.3	1.3	2.2	1.4	2.0	1.8	-1.3
Eye problems/disorders: Cataract	1.5	1.8	4.1	1.1	2.0	1.0	1.2	1.4	1.5	1.1	1.6	-0.3
Risk taking	1.5	2.1	3.3	-1.5	-1.6	-1.3	-1.3	-1.2	-1.3	-1.3	-1.7	1.8
Arm predicted mass (left)	1.5	7.5	23.9	-1.9	-1.0	-1.1	-1.0	-4.7	0.8	-2.7	-2.6	4.9
Type 2 Diabetes (T2D) (2018)	1.4	2.6	3.9	1.5	2.0	1.4	1.5	1.6	1.7	1.9	1.8	0.1
Financial difficulties in last 2 years	1.4	1.8	3.2	-1.4	-1.5	-1.8	-1.8	-0.4	-0.9	-1.3	-1.3	-1.2
Weight	1.4	6.9	20.5	-1.9	-1.2	-1.2	-1.2	-4.5	0.9	-2.5	-2.6	4.5
Hair/balding pattern: Pattern 3	1.4	2.1	6.9	-0.8	-2.6	-1.0	-1.1	0.2	-2.1	-0.6	-1.4	-1.4
Pulse wave reflection index	1.4	1.8	4.3	1.5	0.5	1.1	1.2	1.7	-0.6	1.5	1.0	-2.1
Glaucoma (self-reported)	1.4	1.7	2.8	1.3	1.3	1.3	1.3	1.2	1.2	1.4	1.7	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	5.2	-1.4	-1.2	-1.6	-1.5	-0.1	-2.3	-1.2	-1.2	-0.3
Heart disease (mother)	1.4	1.7	3.8	-1.2	-2.0	-1.2	-1.3	-0.2	-1.8	-1.1	-1.5	-0.6
Medication: Aspirin	1.4	1.8	4.4	1.1	1.4	1.2	1.2	1.3	2.1	1.3	1.3	0.9
Arm fat mass (left)	1.4	5.9	16.9	-1.9	-1.7	-1.2	-1.3	-4.1	0.5	-2.2	-2.7	3.7
Relative age of first facial hair	1.3	2.7	7.0	1.3	1.7	0.8	0.9	2.4	0.8	1.1	2.0	-2.7
Chronic bronchitis/emphysema (father)	1.3	1.6	6.2	0.6	-0.0	0.3	0.2	2.5	0.1	1.3	0.9	-2.2
Impedance of arm (right)	1.3	5.9	22.4	1.3	1.2	0.7	0.7	4.7	0.1	2.2	2.8	-3.7
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	11.4	-2.1	-1.0	-1.7	-1.7	-3.4	-0.9	-2.9	-2.3	1.2
Illnesses of mother	1.3	1.6	3.4	1.8	0.7	1.8	1.8	0.9	0.4	1.2	1.2	-0.5
Exposure to tobacco smoke outside home	1.3	1.7	2.8	-1.4	-1.7	-1.4	-1.5	-1.1	0.2	-0.8	-1.6	1.3
Medication: Aspirin	1.3	1.7	4.5	1.0	1.3	1.1	1.2	1.1	2.1	1.3	1.2	1.1
Arm fat-free mass (left)	1.3	6.7	24.0	-1.6	-0.5	-0.8	-0.7	-4.5	1.1	-2.4	-2.2	4.9
Mean Putamen Volume	1.2	1.4	5.8	0.0	1.8	0.3	0.4	-1.0	1.4	0.1	0.8	2.4
Lupus	1.2	1.9	4.6	1.2	2.1	1.3	1.5	0.2	2.0	0.8	1.3	0.8
Vitamin and mineral supplements	1.2	1.6	7.3	1.0	0.3	0.6	0.6	1.8	0.3	1.1	0.9	-2.7
Pain all over the body in last month	1.2	1.3	4.5	0.4	2.1	0.5	0.5	0.6	1.8	0.8	1.3	0.6
Trunk predicted mass	1.2	6.6	23.3	-1.8	-0.6	-1.0	-1.0	-4.3	0.8	-2.6	-2.2	4.8
Wheeze or whistling in the chest in last year	1.2	2.1	3.4	1.6	0.5	1.5	1.5	1.8	0.7	1.7	1.3	-1.8
Number of children fathered	1.2	1.4	5.5	0.3	1.8	0.4	0.5	0.1	1.5	0.5	0.9	2.3
Chest pain or discomfort	1.2	1.8	2.9	1.6	0.9	1.4	1.4	1.1	0.1	1.4	1.6	-1.7
Ever smoked	1.2	2.0	6.4	1.5	1.0	1.3	1.2	1.1	0.2	1.5	1.4	-2.5
Unable to work because of sickness or disability	1.2	1.6	2.6	-1.2	-1.6	-1.3	-1.3	-1.3	-0.7	-1.3	-1.6	0.4
Intelligence (Savage-Jansen 2018)	1.1	3.2	4.9	1.8	2.0	1.6	1.7	2.2	0.7	1.6	2.0	-2.1
Hearing difficulty/problems: Yes	1.1	1.7	2.4	-1.3	-1.4	-1.2	-1.3	-1.2	-1.3	-1.4	-1.5	0.6
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	2.7	-1.4	-1.3	-1.5	-1.4	-0.7	-1.6	-1.4	-1.3	-0.3
Medication: Simvastatin	1.1	1.6	3.1	1.3	-0.6	1.1	1.0	1.6	0.8	1.8	0.8	-1.6
Trunk fat-free mass	1.1	6.6	23.3	-1.7	-0.6	-1.0	-0.9	-4.3	0.9	-2.6	-2.2	4.8
Medication: Lansoprazole	1.1	1.3	4.7	-0.4	0.8	-0.1	-0.0	-1.9	1.3	-0.8	-0.3	2.2
Medication: Amlodipine	1.1	1.6	2.5	1.6	1.0	1.6	1.6	0.8	0.6	1.6	1.4	-0.6
Arm fat-free mass (right)	1.1	5.8	18.5	-1.6	-1.0	-0.9	-0.9	-4.2	0.5	-2.3	-2.4	4.3
Arm predicted mass (right)	1.1	5.5	19.3	-1.5	-0.8	-0.8	-0.7	-4.0	0.6	-2.2	-2.2	4.4
High cholesterol (Self-reported)	1.1	2.0	4.4	1.5	-0.0	1.1	1.0	1.9	1.2	2.1	1.2	-1.5
Number of operations (self-reported)	1.1	1.7	3.2	1.8	0.8	1.7	1.7	1.0	-0.3	1.4	1.1	-1.1
Heart attack/myocardial infarction (self-reported)	1.1	1.4	4.5	1.2	0.8	0.9	1.0	2.1	0.6	1.2	1.4	-1.1
Irritable Bowel Disease (IBD)	1.0	2.3	9.1	-1.2	0.3	-1.1	-1.1	-2.1	-0.0	-1.4	-1.2	3.0
HbA1C	1.0	1.1	4.2	0.3	1.8	-0.0	0.1	1.1	2.1	0.5	1.2	0.0
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.5	-1.2	-1.2	-1.3	-1.2	0.2	-1.9	-1.1	-1.1	-0.2
Medication: Co-codamol	1.0	1.1	5.0	0.1	-0.8	0.6	0.4	-1.5	0.8	-0.3	-0.9	2.2
Pack years adult smoking proportion	1.0	1.5	2.3	-1.4	-1.0	-1.5	-1.4	-0.9	-1.5	-1.0	-1.3	0.3
Relative age voice broke	1.0	1.5	7.6	1.1	-0.0	0.6	0.7	1.6	0.2	1.1	0.8	-2.8
Stomach or abdominal pain in last month	1.0	1.3	3.8	-0.9	-1.3	-0.8	-0.8	-1.1	-2.0	-0.7	-1.3	0.6
Heart attack	1.0	1.3	3.4	1.1	0.9	1.0	1.0	1.8	0.8	1.1	1.3	-0.8
Arm fat percentage (right)	1.0	4.1	10.4	-1.7	-1.6	-1.1	-1.3	-3.2	0.5	-1.8	-2.3	3.1
Number of live births	1.0	1.5	2.7	1.1	1.3	1.4	1.4	0.5	0.9	1.1	1.2	1.6
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.1	-1.4	-0.1	-1.5	-1.4	-1.1	-0.1	-1.0	-1.0	1.3
Supplements: Calcium	1.0	1.1	2.0	-1.2	-0.7	-1.0	-1.0	-1.3	-0.9	-1.4	-1.1	0.4
Pack years of smoking	1.0	1.4	2.7	-1.4	-0.9	-1.6	-1.5	-0.7	-1.4	-1.0	-1.2	-0.2
Systolic blood pressure, automated reading	0.9	2.7	4.6	-1.7	-2.1	-1.5	-1.6	-2.1	0.3	-1.6	-2.0	1.1
Multivitamins +/- minerals	0.9	1.1	5.5	-0.4	0.5	-0.1	-0.0	-1.8	0.3	-0.8	-0.3	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	6.3	-1.9	-0.9	-1.7	-1.7	-2.5	-0.7	-2.5	-1.9	0.5
High blood pressure (siblings)	0.9	1.3	2.8	-0.9	-0.7	-0.8	-0.8	-1.7	-0.1	-1.3	-1.3	1.6
Health satisfaction	0.9	1.2	2.1	-1.2	-1.1	-1.4	-1.4	-0.7	-1.0	-0.8	-1.5	0.2
Mouth/teeth dental problems: Loose teeth	0.9	1.0	3.4	-0.9	-1.4	-0.9	-0.9	-0.4	-1.9	-0.6	-1.0	-0.2
Illnesses of father: Heart disease	0.9	1.3	3.4	-1.1	-1.2	-1.0	-0.9	-1.9	-0.5	-1.2	-1.4	0.3
Arm fat percentage (left)	0.9	3.6	10.0	-1.5	-1.6	-0.9	-1.1	-3.2	0.5	-1.6	-2.2	2.9
Back pain experienced in last month	0.9	1.4	4.8	0.5	0.6	1.1	1.1	-1.9	0.8	0.1	-0.1	2.2
Medication: Paracetamol	0.9	1.4	4.8	-0.6	-1.5	-0.1	-0.2	-2.2	-1.0	-1.4	-1.5	0.6
Pain experienced in last month	0.9	1.5	5.2	0.8	-0.3	0.4	0.3	2.3	-0.7	1.0	0.8	-2.2
Bipolar Disorder or Schizophrenia	0.8	1.9	2.9	1.4	1.7	1.4	1.4	1.3	1.0	1.4	1.6	-0.9
Lung FEV1/FVC ratio	0.8	4.2	15.8	-1.5	-1.2	-1.2	-1.4	-4.0	-0.1	-2.0	-2.1	2.5
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.1	0.5	1.2	0.3	0.4	1.5	1.3	1.0	1.2	-0.0
Supplements: Zinc	0.8	0.8	2.0	-0.9	-0.9	-0.7	-0.8	-0.8	-0.6	-0.9	-1.0	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	2.9	1.6	1.2	1.7	1.6	1.0	1.1	1.7	1.6	-0.2
Exposure to tobacco smoke at home	0.8	0.9	2.0	-1.3	-0.6	-1.4	-1.4	-0.5	-0.2	-1.0	-0.9	0.4
Loud music exposure frequency	0.8	0.9	3.0	0.3	1.3	0.4	0.5	-0.4	1.7	0.4	0.7	1.5
Medication: Paracetamol	0.8	1.4	6.2	0.1	-0.9	0.7	0.7	-2.5	-0.4	-1.0	-1.0	1.5
Headache pain in last month	0.8	1.4	5.1	0.1	1.9	0.5	0.7	-1.2	1.1	-0.5	0.5	2.2
Medication for pain relief, constipation, heartburn	0.8	1.4	5.6	-0.4	-0.1	-0.9	-0.9	1.9	-1.1	0.3	0.3	-2.4
Medication: Allopurinol	0.8	1.1	2.5	-0.7	-1.3	-0.6	-0.7	-1.6	-1.3	-0.9	-1.2	0.6
Suffer from ‘nerves’	0.8	1.2	3.0	1.7	0.4	1.7	1.6	-0.0	0.0	0.8	0.6	-1.2
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.0	-0.8	-1.4	-0.4	-0.5	-1.7	-0.2	-0.8	-1.3	1.0
Average weekly beer plus cider intake	0.8	1.2	3.1	-0.9	-1.8	-0.8	-0.8	-1.0	-1.1	-1.0	-1.4	0.6
Basal cell carcinoma (self-reported)	0.8	0.9	1.5	1.1	0.6	1.2	1.2	0.6	0.9	1.1	1.1	0.1
Depressed Affect (Nagel 2018)	0.7	1.4	3.9	-1.1	-1.8	-1.2	-1.2	0.6	-2.0	-0.6	-1.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.9	1.3	1.3	1.1	1.1	1.2	0.3	0.7	1.2	-2.2
Average weekly spirits intake	0.7	0.9	3.6	-0.0	1.5	0.1	0.2	0.6	1.9	0.1	1.0	0.5
Townsend deprivation index at recruitment	0.7	1.0	2.0	-1.2	-1.0	-1.4	-1.4	-0.5	0.4	-1.1	-0.6	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.3	-1.2	-0.8	-1.5	-1.4	0.8	-0.6	-0.6	-0.7	-0.7
Past tobacco smoking	0.7	1.2	4.5	-1.2	-0.9	-0.8	-0.7	-0.9	-0.1	-1.1	-1.0	2.1
Alcohol usually taken with meals	0.7	1.1	2.0	1.1	1.3	1.4	1.4	0.2	-0.8	0.7	1.1	0.6
Diabetes (self-reported)	0.7	1.1	2.2	1.2	0.5	1.0	1.0	1.4	0.4	1.5	1.0	-1.0
Fluid intelligence score	0.7	1.4	4.0	1.2	2.0	1.1	1.2	0.8	0.6	0.6	1.4	-1.1
Depression (self-reported)	0.7	0.8	2.6	-0.8	-0.4	-1.1	-1.0	0.5	-1.2	-0.6	-0.3	-1.6
Birth weight	0.7	1.5	2.8	-1.6	-0.7	-1.6	-1.6	-0.8	-0.2	-1.7	-1.4	-0.1
Emphysema/chronic bronchitis	0.7	0.8	2.9	0.2	0.1	-0.1	-0.1	1.7	-0.4	0.7	0.7	-1.7
Migraine (self-reported)	0.7	0.9	2.5	0.7	1.3	0.8	0.9	0.2	1.6	0.6	1.1	0.7
Age at last live birth	0.7	1.0	2.1	1.0	1.1	0.8	0.8	1.4	0.1	0.8	1.4	-0.8
Family relationship satisfaction	0.7	0.8	1.9	-1.2	-0.6	-1.4	-1.4	-0.3	-0.5	-1.0	-0.9	0.3
Leg pain on walking	0.7	0.8	2.2	-0.7	-0.3	-0.6	-0.5	-1.5	-0.4	-1.1	-0.9	1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.4	0.7	-1.0	0.5	0.3	1.1	-1.5	0.5	0.1	-2.1
Alzheimer’s Disease (in father)	0.6	0.7	1.3	0.9	0.4	0.9	1.0	0.4	0.6	1.1	0.7	-0.9
Systolic Blood Pressure	0.6	3.1	7.6	-1.8	-2.8	-1.8	-1.9	-1.8	-0.2	-1.2	-2.0	1.1
Smoking Status	0.6	1.3	2.5	1.1	1.4	0.7	0.7	0.8	1.5	1.1	1.1	-1.6
Medication for hormone replacement therapy	0.6	0.6	2.7	-0.0	0.9	0.2	0.2	-1.3	0.6	-0.4	0.1	1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	1.9	1.3	1.0	1.2	1.2	1.4	0.4	1.4	1.4	-1.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.8	-0.7	-1.3	-0.7	-0.8	0.4	-1.4	-0.4	-0.6	-0.2
Qualifications: CSEs or equivalent	0.6	0.7	2.1	-0.7	-1.5	-0.7	-0.7	-0.5	-0.8	-0.8	-1.1	-0.6
Medication: Atenolol	0.6	0.8	2.1	0.9	0.6	1.3	1.2	-0.3	0.2	0.5	0.4	1.4
Nervous feelings	0.6	1.1	2.2	1.5	-0.1	1.5	1.4	0.6	-1.0	1.2	0.7	-0.6
Hearing difficulty/problems with background noise	0.6	1.0	4.1	-0.6	-0.1	-0.3	-0.3	-2.0	0.3	-1.0	-0.6	1.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.5	0.5	0.2	0.2	0.3	1.4	0.1	0.7	0.8	-1.6
Prospective memory result	0.6	0.8	2.2	-1.1	0.2	-1.1	-1.0	-0.7	0.5	-0.6	-0.4	1.5
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.9	-0.3	0.7	-0.2	-0.1	-2.0	-0.1	-0.9	-0.6	1.7
Number of full brothers	0.6	0.7	3.2	0.7	0.2	0.7	0.6	0.8	1.8	0.8	0.7	-0.7
Whole body fat mass	0.6	2.7	8.7	-0.9	-0.9	-0.3	-0.4	-2.9	1.0	-1.2	-1.6	3.0
Leg fat mass (right)	0.6	2.3	8.5	-0.6	-0.8	-0.0	-0.1	-2.9	0.9	-1.1	-1.6	2.7
Handedness (chirality/laterality): Left-handed	0.6	0.8	2.2	0.9	-0.1	0.8	0.7	0.9	-0.9	0.8	0.6	-1.5
Friendships satisfaction	0.6	0.7	1.5	-1.1	0.0	-1.2	-1.1	-0.6	-0.2	-0.8	-0.7	1.2
Medication for cholesterol	0.6	0.9	4.0	-0.5	-0.0	-0.7	-0.6	1.1	-1.3	-0.3	0.0	-2.0
Medication: Blood pressure	0.6	1.1	4.2	0.7	-0.1	1.0	0.9	-1.3	1.1	0.6	-0.0	2.0
Illnesses of father: High blood pressure	0.6	0.8	1.7	1.3	-0.3	1.3	1.3	0.6	-0.6	0.9	0.6	-0.4
Diastolic blood pressure, automated reading	0.6	1.7	7.8	0.7	-0.3	1.2	1.1	-2.8	1.0	-0.1	-0.7	1.7
Leg fat mass (left)	0.6	2.5	9.2	-0.6	-0.8	-0.1	-0.2	-3.0	0.9	-1.0	-1.7	2.7
Depression (Nagel 2018)	0.5	0.8	3.1	-0.2	-0.5	-0.4	-0.3	1.8	-1.1	0.0	0.1	-1.6
Schizophrenia (2018)	0.5	1.1	2.7	1.0	1.6	0.9	0.8	1.1	0.5	1.2	1.4	-0.3
Alzheimer’s Disease (in mother)	0.5	0.6	1.8	0.6	0.6	0.7	0.6	0.2	1.3	0.5	0.7	-1.1
Neuroticism (2016)	0.5	0.7	1.5	-0.6	-1.2	-0.7	-0.7	-1.0	-0.8	-0.5	-1.1	0.4
Primary Biliary Cirrhosis	0.5	0.8	2.4	-0.9	-0.6	-1.1	-1.0	0.2	-1.5	-0.4	-0.6	-0.9
Blood Red Count	0.5	4.7	7.5	-2.2	-2.6	-1.8	-1.8	-2.2	-2.4	-2.1	-2.7	1.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.0	1.0	-0.1	0.9	0.9	0.4	0.1	0.8	0.5	-1.4
High blood pressure	0.5	1.5	3.3	1.6	-0.0	1.8	1.7	-0.7	0.9	1.5	0.4	0.9
Trunk fat mass	0.5	2.3	6.9	-1.1	-0.8	-0.6	-0.6	-2.5	0.8	-1.2	-1.5	2.6
Worrier / anxious feelings	0.5	0.9	2.6	1.4	0.2	1.6	1.5	-0.4	-0.4	0.7	0.5	0.3
Noisy workplace	0.5	0.7	1.9	-0.8	-0.9	-0.7	-0.7	-1.4	-0.3	-0.7	-0.9	0.4
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.6	0.7	-0.0	0.4	0.4	1.2	-0.5	0.9	0.6	-1.6
Medication: Seretide 50 evohaler	0.5	0.6	2.7	-0.2	-0.9	-0.3	-0.3	-0.1	-0.9	-0.1	-0.6	-1.6
Supplements: Vitamin C	0.5	0.6	4.3	0.3	0.2	0.6	0.6	-0.6	0.1	0.2	0.3	2.1
Hypertension (Self-reported)	0.5	1.3	3.0	1.5	-0.2	1.7	1.6	-0.3	0.6	1.5	0.4	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.1	-0.3	-1.0	-0.2	-0.2	-0.7	-0.9	-0.6	-0.8	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.2	0.7	0.5	0.9	0.9	-0.3	0.5	0.4	0.3	1.5
Mineral and other dietary supplements	0.5	0.6	2.2	0.4	1.5	0.0	0.2	1.1	0.2	0.6	1.0	-0.8
Medication: Gliclazide	0.5	0.6	1.6	0.6	1.3	0.5	0.6	0.1	0.9	0.8	0.7	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	4.4	-0.7	-0.5	-0.5	-0.5	-2.1	-0.6	-1.6	-1.2	0.1
Wears glasses or contact lenses	0.5	0.5	1.8	0.8	0.2	0.9	1.0	0.4	-0.5	0.0	0.4	-1.3
Hearing aid user	0.5	0.6	1.2	-0.7	-0.6	-0.6	-0.6	-0.7	-1.0	-0.6	-0.8	1.1
Commuting to job workplace: Public transport	0.5	0.5	1.5	0.7	0.0	0.7	0.7	0.8	0.8	0.7	0.5	-1.2
Vascular/heart problems diagnosed by doctor	0.5	1.5	3.1	-1.5	0.0	-1.8	-1.7	0.9	-1.0	-1.4	-0.3	-1.2
Bipolar Disorder (2018)	0.4	0.6	1.6	0.4	0.7	0.3	0.3	1.0	0.8	0.6	0.9	-1.3
Neuroticism (Nagel 2018)	0.4	0.9	4.7	0.4	-1.4	0.5	0.4	0.7	-2.2	0.4	-0.4	-0.6
Worry (Nagel 2018)	0.4	0.8	1.7	1.1	-0.7	1.3	1.2	-0.5	-1.3	0.5	-0.1	-0.0
Ovarian Cancer	0.4	0.5	1.5	-1.0	0.1	-1.2	-1.1	0.5	0.0	-0.3	-0.1	-0.3
Prostate Cancer	0.4	0.6	2.3	0.2	-0.8	0.4	0.3	-0.7	-1.5	0.0	-0.6	1.0
Blood Eosinophil Count	0.4	3.2	9.0	1.3	1.9	0.8	0.9	3.0	1.5	1.9	2.3	-1.5
Hand grip strength (left)	0.4	1.0	2.0	0.8	1.4	1.0	1.1	-0.9	0.9	-0.0	0.3	1.4
Sensitivity / hurt feelings	0.4	0.7	1.1	0.9	-0.7	0.9	0.8	0.7	-1.0	1.0	0.1	-0.7
Severe depression (siblings)	0.4	0.5	3.0	-0.2	-1.0	-0.1	-0.3	-0.3	-0.2	-0.1	-0.4	-1.7
Age when periods started (menarche)	0.4	0.9	5.8	0.4	0.1	0.0	0.1	1.2	-0.1	0.5	0.6	-2.4
Waist circumference	0.4	1.3	5.2	-0.6	-0.0	-0.2	-0.2	-1.7	1.6	-0.7	-0.7	2.3
Falls in the last year	0.4	0.6	3.3	0.4	0.0	0.0	0.0	1.2	0.4	0.4	0.3	-1.8
Happiness	0.4	0.5	1.9	-0.2	1.1	-0.4	-0.3	0.1	0.8	0.1	0.2	1.4
Peak expiratory flow (PEF)	0.4	1.0	2.7	-0.9	-0.2	-0.8	-0.7	-1.6	-0.7	-1.4	-1.0	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.3	0.1	-1.1	0.3	0.2	-0.9	-0.9	0.1	-0.7	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	5.8	0.3	0.1	0.7	0.7	-0.8	0.8	-0.3	0.1	2.4
Long-standing illness, disability or infirmity	0.4	0.7	2.8	-0.4	0.6	-0.4	-0.3	-1.1	0.8	-0.5	-0.3	1.7
Osteoarthritis (self-reported)	0.4	0.5	1.0	-0.8	-1.0	-0.9	-1.0	-0.5	0.2	-0.3	-1.0	-0.4
Illnesses of father: None of the above (group 1)	0.4	0.4	1.4	-0.5	0.4	-0.4	-0.4	-0.8	0.7	-0.8	-0.2	1.2
Average weekly champagne plus white wine intake	0.4	0.6	1.4	-1.0	-0.0	-1.2	-1.1	-0.1	-0.5	-1.1	-0.6	0.1
Mother’s age at death	0.4	0.5	1.7	0.1	1.3	-0.1	0.0	0.5	0.5	0.4	0.8	-1.2
Fractured/broken bones in last 5 years	0.4	0.5	1.7	0.6	1.3	0.6	0.7	-0.1	1.0	-0.0	0.7	0.3
Commuting to job workplace: Cycle	0.4	0.5	2.2	-0.6	-0.6	-0.7	-0.8	0.1	-0.4	-0.5	-0.4	-1.5
Alzheimer’s Disease (including proxy)	0.3	0.5	1.7	0.5	0.5	0.4	0.4	-0.3	1.3	0.7	0.5	-1.1
Reaction Time	0.3	0.5	1.9	-0.2	1.3	-0.2	-0.0	-0.6	0.7	0.2	0.5	1.4
Body Mass Index (BMI) (2010)	0.3	0.4	3.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.8	0.0
Ulcerative Colitis	0.3	0.5	2.8	-0.5	-0.1	-0.3	-0.3	-1.7	0.0	-0.5	-0.8	0.0
Hypothyroidism (self reported)	0.3	0.7	3.3	-0.0	1.4	0.1	0.3	-0.1	0.8	-0.1	0.6	1.8
Neuroticism	0.3	0.7	3.9	0.1	-1.4	0.2	0.1	0.2	-2.0	0.2	-0.5	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.9	-0.7	0.3	-1.0	-0.8	0.1	-0.5	-0.5	-0.4	0.3
Average weekly fortified wine intake	0.3	0.4	1.8	0.2	0.1	0.2	0.1	1.3	0.5	0.7	0.6	-0.4
Fed-up feelings	0.3	0.5	1.3	0.5	-1.1	0.3	0.2	1.1	-0.5	0.7	-0.1	-0.7
Taking other prescription medications	0.3	0.4	1.9	-0.1	0.1	-0.0	0.1	-0.8	1.0	-0.3	-0.2	1.4
Forced vital capacity (FVC)	0.3	1.1	3.1	-1.2	0.0	-1.1	-1.0	-1.4	-0.2	-1.8	-1.0	0.0
Allergy	0.3	0.7	1.3	1.1	0.7	1.0	0.9	0.8	0.4	0.9	0.8	-0.7
Neuroticism score	0.3	0.5	1.3	0.9	-0.6	1.0	0.9	0.2	-1.1	0.7	0.1	-0.1
Pulse rate	0.3	0.5	2.0	-0.2	-0.5	-0.0	-0.1	-1.4	0.6	-0.4	-0.4	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.4	-0.3	-0.3	-0.1	-0.1	-1.2	0.2	-0.9	-0.6	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.1	-0.5	-0.2	-0.7	-0.7	-0.8	-0.6	-0.8	-0.6	-1.1
Hair/balding pattern: Pattern 4	0.3	0.7	1.2	0.8	1.0	1.0	1.1	0.4	1.1	0.9	0.9	0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	2.6	-1.2	0.1	-1.1	-1.0	-1.3	0.0	-1.6	-0.8	-0.3
Age at first live birth	0.3	0.6	1.0	0.9	0.9	1.0	1.0	0.5	-0.0	0.7	0.9	0.2
Medication: Blood pressure	0.3	0.6	1.2	0.9	0.1	1.1	1.0	0.2	-0.3	1.1	0.4	0.9
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.7	0.5	-0.4	0.6	0.5	-0.8	-0.7	0.4	-0.3	0.3
Illnesses of siblings: Diabetes	0.3	0.3	1.8	0.3	0.8	0.3	0.3	0.0	1.3	0.2	0.5	0.2
Smoking status: Previous	0.3	0.5	2.5	0.8	0.7	0.5	0.4	0.1	0.2	0.6	0.5	-1.6
Ever had bowel cancer screening	0.3	0.3	0.7	0.5	0.9	0.8	0.9	-0.5	0.5	-0.0	0.3	0.1
Commuting to job workplace: Walk	0.3	0.4	1.4	-0.3	0.5	-0.5	-0.4	1.2	0.6	0.0	0.5	-0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.8	0.6	-0.2	0.6	0.6	0.0	0.4	0.3	0.1	-1.4
Medication: Bendroflumethiazide	0.3	0.4	2.5	0.2	0.0	0.5	0.6	-0.4	0.6	0.5	0.1	1.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.0	1.0	-0.1	-0.1	1.1	0.4	0.0	0.7	0.9
Age started oral contraceptive pill	0.3	0.4	1.7	-0.5	-0.7	-0.4	-0.3	-1.3	-0.1	-0.6	-0.7	0.4
Crohns Disease (2017)	0.2	0.4	1.3	-0.7	0.2	-0.8	-0.8	-0.4	0.1	-0.6	-0.5	1.1
Rheumatoid Arthritis	0.2	0.2	1.0	0.3	0.6	0.4	0.5	0.0	0.3	0.1	0.3	1.0
Schizophrenia (2014)	0.2	0.4	2.0	0.1	0.6	-0.1	-0.1	1.4	-0.7	0.4	0.7	0.0
Blood White Count	0.2	1.7	3.3	-1.8	-1.4	-1.8	-1.7	-0.6	-0.4	-1.4	-1.3	-0.5
Heel T-Score	0.2	1.5	3.6	-0.9	-1.9	-1.1	-1.2	-0.6	-0.8	-0.6	-1.3	-1.8
Height	0.2	4.2	6.7	1.6	2.4	1.7	2.0	2.5	2.6	1.5	2.6	-0.0
Respiratory disease	0.2	0.5	1.9	-0.2	-1.2	-0.2	-0.2	-0.4	-1.4	-0.1	-0.6	-0.9
Number of treatments/medications taken	0.2	0.3	0.8	0.5	-0.2	0.6	0.6	0.2	0.8	0.6	0.3	0.9
Ever had hysterectomy (womb removed)	0.2	0.3	1.7	0.1	-0.2	0.4	0.4	-0.5	0.3	0.2	-0.2	1.3
Diabetes (father)	0.2	0.2	1.6	-0.2	-0.3	-0.1	-0.1	-0.1	-1.3	-0.3	-0.3	-0.1
Trunk fat percentage	0.2	0.8	2.2	-0.6	-0.6	-0.3	-0.4	-1.5	0.9	-0.6	-0.9	1.5
Current tobacco smoking	0.2	0.3	1.0	-0.0	1.0	-0.2	-0.1	0.1	0.9	0.2	0.6	-0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	-0.3	-0.9	-0.2	-0.2	-0.2	-0.5	-0.4	-0.5	0.6
Medication: Levothyroxine sodium	0.2	0.3	1.0	0.1	0.6	0.4	0.5	-0.5	1.0	-0.1	0.3	1.0
Had menopause	0.2	0.2	0.6	0.4	0.2	0.5	0.5	-0.8	0.6	0.4	0.1	-0.2
Had other major operations	0.2	0.2	0.7	0.4	-0.2	0.3	0.3	0.5	-0.5	0.3	0.1	-0.9
Mouth/teeth dental problems	0.2	0.4	1.1	-0.0	0.7	0.3	0.3	-0.8	1.0	-0.4	0.2	0.9
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	-0.5	-0.5	-0.7	-0.7	0.1	-0.7	-0.3	-0.5	0.1
Medication: Ramipril	0.2	0.3	0.6	-0.6	-0.7	-0.8	-0.8	-0.4	-0.4	-0.2	-0.6	-0.2
Time employed in main current job	0.2	0.3	0.6	0.5	-0.1	0.7	0.6	0.4	0.7	0.5	0.2	-0.5
Father’s age at death	0.2	0.2	0.7	-0.4	-0.1	-0.3	-0.3	-0.1	-0.7	-0.5	-0.2	0.8
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.1	0.7	1.1	0.6	0.6	0.5	-0.0	0.3	0.8	-0.5
Standing height	0.2	1.5	3.5	0.8	1.6	1.0	1.3	1.0	1.9	0.6	1.5	0.7
Tense / ‘highly strung’	0.2	0.4	0.8	0.8	-0.2	0.9	0.9	-0.3	-0.5	0.6	0.1	0.8
Birth weight of first child	0.2	0.3	1.0	-0.7	0.4	-0.8	-0.7	0.3	1.0	-0.4	-0.2	0.1
Blood clot in the leg (DVT)	0.2	0.2	0.6	0.3	-0.8	0.6	0.5	0.1	-0.7	0.3	-0.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.9	-0.7	-0.2	-0.8	-0.8	-0.0	-0.5	-0.9	-0.3	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.6	-0.2	1.3	-0.1	0.1	-0.0	1.1	-0.3	0.5	0.9
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.3	0.4	-0.5	0.4	0.4	0.1	0.4	0.6	0.1	-1.2
Body fat percentage	0.2	0.8	2.6	-0.2	-0.5	0.2	0.1	-1.6	1.0	-0.3	-0.8	1.6
Leg fat percentage (right)	0.2	0.8	3.3	0.2	-0.5	0.6	0.5	-1.8	0.8	-0.1	-0.9	1.1
Worry too long after embarrassment	0.2	0.3	1.2	0.5	0.1	0.5	0.6	0.2	-1.1	0.3	0.3	-0.3
Shortness of breath walking on level ground	0.2	0.3	1.3	-0.3	0.3	-0.2	-0.2	-0.6	0.0	-0.4	-0.5	1.1
Mean time to correctly identify matches	0.2	0.4	1.9	0.1	1.4	0.0	0.1	0.4	0.1	0.6	0.9	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.1	-0.1	0.3	-0.0	-0.0	-0.9	0.6	-0.2	-0.2	1.0
Had major operations	0.2	0.2	0.4	0.5	0.6	0.5	0.5	0.4	-0.2	0.5	0.5	0.5
Smoking status: Current	0.2	0.3	1.1	0.1	1.0	0.0	0.1	0.4	0.8	0.3	0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.3	0.5	-0.5	0.5	0.5	-0.6	-0.5	0.4	-0.2	-0.0
Alcohol drinker status: Never	0.2	0.2	0.8	0.0	-0.2	0.1	0.0	0.9	-0.8	-0.2	0.2	-0.6
Leg fat percentage (left)	0.2	0.8	3.6	0.2	-0.4	0.5	0.4	-1.9	0.8	-0.1	-0.9	1.2
Irritability	0.2	0.3	0.8	0.6	-0.4	0.9	0.8	0.1	-0.7	0.5	0.3	0.4
Myopia	0.2	0.3	0.9	-0.5	-0.3	-0.4	-0.3	-0.3	-1.0	-0.6	-0.2	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.6	0.6	-0.6	0.8	0.7	0.4	-0.5	0.6	0.0	0.0
Crohns Disease (2012)	0.1	0.1	0.3	-0.4	-0.2	-0.5	-0.5	0.3	0.0	-0.1	-0.3	0.0
LDL Cholesterol	0.1	0.2	0.9	0.0	0.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0
Triglycerides	0.1	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	1.0	0.0
Allergy or Eczema	0.1	0.3	1.2	-0.2	0.5	-0.1	0.0	-0.9	0.3	-0.2	-0.0	1.1
Cardiovascular Disease	0.1	0.5	1.8	0.5	-0.2	0.6	0.6	-1.0	0.5	0.5	-0.0	1.3
Lung FVC	0.1	0.6	2.1	-0.4	0.1	-0.2	-0.2	-1.1	-0.1	-1.0	-0.7	-1.5
Tanning	0.1	1.6	3.0	1.3	1.7	1.2	1.4	0.8	0.8	1.3	1.3	-1.2
Hand grip strength (right)	0.1	0.2	0.4	0.4	0.5	0.5	0.6	-0.6	0.6	-0.3	0.0	0.3
Maternal smoking around birth	0.1	0.2	0.3	0.6	0.5	0.5	0.5	0.3	0.1	0.6	0.4	0.5
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.6	0.3	-0.4	-0.4	-0.6	-0.1	-0.5	-0.3	0.9
Sitting height	0.1	0.9	5.8	-0.3	1.0	0.1	0.3	-0.4	0.8	-0.6	0.2	2.4
Qualifications: None of the above	0.1	0.2	0.5	-0.4	-0.5	-0.6	-0.5	0.3	0.4	0.0	-0.1	-0.7
Illnesses of siblings	0.1	0.2	0.7	0.1	0.5	0.1	0.2	0.8	-0.6	0.4	0.5	-0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.3	0.1	-0.6	0.1	0.0	-0.5	0.0	0.0	-0.2	-0.6
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	-0.4	-0.1	-0.4	-0.5	-0.2	0.0	0.0	-0.3	0.5
Asthma	0.1	0.3	1.2	-0.1	-0.8	0.1	0.1	-1.1	-0.3	-0.2	-0.5	0.1
Qualifications: College or University degree	0.1	0.2	0.8	0.0	0.8	-0.0	0.0	0.9	-0.4	0.1	0.4	0.2
Neck or shoulder pain in last month	0.1	0.2	0.7	-0.1	-0.9	-0.0	-0.0	-0.6	-0.2	-0.1	-0.5	-0.4
Medication: Ibuprofen	0.1	0.1	0.4	-0.1	0.1	-0.0	0.1	-0.6	0.3	-0.4	-0.0	-0.1
Pulse rate, automated reading	0.1	0.3	2.2	0.2	-0.2	0.2	0.2	-0.3	1.5	0.3	0.0	-0.5
Comparative height size at age 10	0.1	0.8	4.1	0.1	1.2	0.3	0.5	0.1	2.0	0.1	0.8	0.5
Number of full sisters	0.1	0.1	0.3	0.3	0.1	0.3	0.1	0.1	0.5	0.4	0.2	0.2
Overall health rating	0.1	0.3	1.2	0.5	-0.1	0.6	0.6	-0.2	-0.1	0.5	-0.0	1.1
Mood swings	0.1	0.2	1.2	-0.2	-0.6	-0.1	-0.1	0.1	-0.4	0.3	-0.2	1.1
Asthma (self-reported)	0.1	0.2	0.9	0.2	-0.6	0.3	0.3	-0.9	-0.2	0.0	-0.2	-0.1
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.5	0.4	0.5	0.6	-0.1	0.5	0.5	0.3	0.3
Miserableness	0.1	0.2	0.4	0.5	-0.3	0.5	0.5	0.5	-0.1	0.6	0.2	-0.2
Guilty feelings	0.1	0.2	0.8	-0.0	-0.9	-0.0	-0.1	-0.3	-0.6	-0.3	-0.3	-0.5
Cholesterol lowering medication	0.1	0.2	0.4	0.4	-0.2	0.3	0.2	0.5	0.7	0.3	0.3	-0.4
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.7	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Chronotype (morning person)	0.0	0.1	0.3	-0.3	-0.2	-0.4	-0.3	-0.3	0.4	-0.2	0.0	0.6
Hair Pigment	0.0	0.4	0.9	-0.6	-0.2	-0.7	-0.7	-1.0	-0.7	-0.8	-0.6	-0.5
Qualifications: nursing, teaching	0.0	0.1	0.2	0.3	0.4	0.2	0.2	0.2	-0.4	0.2	0.1	-0.1

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