[Hub]/) : Traits : Whole body fat-free mass : ← →

chr13:47,822,976-52,109,040

Best TWAS P=3.72e-29 · Best GWAS P=2.48e-64 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	-7.40	-11.2	3.7e-29	0.61	0.11	0.89	TRUE
19	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	8.70	9.0	1.8e-19	-0.11	0.51	0.02	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DLEU7	0.05	0.00	blup	581	0.02	1.6e-03	1.56	7.3	2.8e-13	-0.46	0.08	0.21	TRUE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	6.48	-7.1	1.1e-12	0.06	0.01	0.98	TRUE
26	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	6.37	-6.8	1.3e-11	0.08	1.00	0.00	TRUE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	6.48	-6.5	8.2e-11	0.04	0.01	0.89	TRUE
33	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-1.31	-6.3	3.5e-10	0.06	0.29	0.71	TRUE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EBPL	0.21	0.14	enet	15	0.19	3.6e-21	-1.31	-5.5	4.3e-08	0.08	1.00	0.00	TRUE
15	GTEx	Breast Mammary Tissue (Female)	SUCLA2	0.07	0.13	lasso	4	0.04	2.9e-02	5.32	-5.4	7.0e-08	-0.01	0.01	0.74	TRUE
7	GTEx	Artery Tibial	RCBTB2	0.14	0.01	enet	10	0.07	6.4e-06	1.58	-5.3	1.3e-07	-0.06	0.02	0.10	TRUE
34	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	8.60	8.6	9.1e-18	-0.10	0.01	0.96	FALSE
25	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	6.62	-7.7	1.1e-14	0.03	1.00	0.00	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	8.74	-7.5	4.4e-14	0.06	0.00	0.46	FALSE
23	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	6.88	-7.1	1.7e-12	0.02	1.00	0.00	FALSE
10	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	8.10	-7.0	2.2e-12	0.05	0.86	0.01	FALSE
20	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	8.10	-6.9	3.9e-12	0.07	0.38	0.04	FALSE
35	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	8.10	-6.9	3.9e-12	0.07	0.00	1.00	FALSE
5	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	6.46	-6.7	2.8e-11	0.14	1.00	0.00	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	6.37	-6.6	3.7e-11	0.02	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.34	-6.6	5.4e-11	0.04	1.00	0.00	FALSE
11	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	8.10	-6.4	1.6e-10	0.14	0.18	0.15	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	8.46	-6.3	3.4e-10	0.22	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	-5.80	6.2	4.8e-10	0.02	0.13	0.25	FALSE
17	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	6.46	-6.2	7.1e-10	0.03	1.00	0.00	FALSE
24	GTEx	Spleen	RCBTB1	0.37	0.02	lasso	5	0.04	3.5e-02	0.51	-6.2	7.5e-10	0.01	0.04	0.10	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	8.10	-6.1	8.2e-10	0.12	0.00	1.00	FALSE
4	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	8.10	-6.1	1.0e-09	0.09	0.88	0.01	FALSE
21	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	6.46	-6.0	1.5e-09	-0.02	0.92	0.01	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	6.46	-6.0	2.0e-09	0.00	1.00	0.00	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	6.37	-6.0	2.1e-09	0.03	1.00	0.00	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	6.48	-5.9	4.1e-09	0.12	0.13	0.09	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	EBPL	0.28	0.10	enet	17	0.26	7.7e-25	-1.31	-5.8	4.8e-09	0.02	0.24	0.76	FALSE
8	GTEx	Brain Caudate basal ganglia	EBPL	0.41	0.06	lasso	7	0.12	2.1e-04	6.37	-5.8	6.8e-09	0.02	0.11	0.17	FALSE
14	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	6.48	-5.8	7.7e-09	0.08	0.06	0.13	FALSE
27	METSIM	Adipose	EBPL	0.32	0.12	lasso	7	0.27	1.4e-39	6.62	-5.7	1.3e-08	0.03	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	EBPL	0.07	0.03	enet	11	0.06	2.1e-12	6.48	-5.6	1.9e-08	0.04	0.06	0.94	FALSE
18	GTEx	Heart Atrial Appendage	EBPL	0.17	0.04	lasso	5	0.05	2.2e-03	8.10	-5.6	2.0e-08	0.07	0.26	0.03	FALSE
9	GTEx	Brain Cerebellar Hemisphere	EBPL	0.54	0.32	enet	17	0.34	1.2e-09	0.34	-5.6	2.3e-08	0.08	0.65	0.02	FALSE
6	GTEx	Artery Coronary	EBPL	0.48	0.03	enet	99	0.12	9.7e-05	8.10	-5.5	3.1e-08	0.04	0.29	0.04	FALSE
12	GTEx	Brain Frontal Cortex BA9	EBPL	0.50	0.20	enet	18	0.34	7.0e-10	0.34	-5.1	3.1e-07	0.03	0.46	0.04	FALSE