TWAS
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Usage
Models
Genes
Traits
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Traits
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Whole body fat-free mass
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chr15:41,221,067-42,889,047
Best TWAS P=2.07e-10 · Best GWAS P=1.3e-10 conditioned to 0.000258
41.2M
41.4M
41.6M
41.8M
42M
42.2M
42.4M
42.6M
42.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
CHP
0.06
0.01
blup
54
0.03
4.7e-04
-3.8
6.4
2.1e-10
0.03
0.04
0.20
TRUE
1
GTEx
Thyroid
RP11-23P13.6
0.07
0.00
lasso
5
0.01
9.6e-02
-2.8
5.3
1.4e-07
0.66
0.05
0.55
TRUE
2
YFS
Blood
MGA
0.01
0.00
blup
454
0.00
7.1e-02
-3.8
-5.5
3.2e-08
-0.27
0.12
0.10
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CHP
0.21
0.11
lasso
4
0.12
5.1e-13
-5.1
5.5
3.7e-08
0.08
0.00
1.00
FALSE