TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat-free mass
:
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chr20:60,874,972-62,270,930
Best TWAS P=1.55e-07 · Best GWAS P=3.2e-11 conditioned to 1.15e-05
60.8M
61M
61.2M
61.4M
61.6M
61.8M
62M
62.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
GID8
0.18
0.02
lasso
3
0.06
0.00024
-6.6
-5.2
1.5e-07
0.9
0.01
0.99
TRUE