[Hub]/) : Traits : Whole body fat-free mass : ← →

chr1:10,391,536-12,013,869

Best TWAS P=2.25e-20 · Best GWAS P=4.55e-18 conditioned to 0.22

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	8.4	9.2	2.3e-20	0.87	0.08	0.92	TRUE
12	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	8.6	9.0	3.3e-19	0.93	0.02	0.91	FALSE
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	8.7	8.7	2.3e-18	0.99	0.01	0.99	FALSE
7	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	8.6	8.7	5.4e-18	0.94	0.02	0.97	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	8.7	8.6	6.5e-18	1.00	0.01	0.99	FALSE
8	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	8.6	8.5	1.3e-17	0.96	0.02	0.94	FALSE
15	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	8.4	8.5	1.7e-17	0.89	0.03	0.97	FALSE
10	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	8.6	8.5	2.5e-17	0.97	0.01	0.98	FALSE
9	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	8.4	8.4	3.2e-17	0.91	0.04	0.77	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	8.3	8.4	3.3e-17	0.91	0.07	0.65	FALSE
6	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	8.0	8.2	1.7e-16	0.90	0.05	0.73	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MTOR	0.13	0.15	lasso	4	0.15	5.6e-18	8.4	8.2	2.1e-16	0.88	0.05	0.95	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	8.3	8.2	2.4e-16	0.88	0.03	0.74	FALSE
5	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	8.7	8.2	3.2e-16	0.96	0.02	0.96	FALSE
4	GTEx	Adipose Subcutaneous	EXOSC10	0.17	0.00	lasso	3	0.00	1.8e-01	8.5	8.0	1.1e-15	0.94	0.02	0.56	FALSE
21	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MASP2	0.05	0.03	blup	30	0.04	6.0e-03	2.8	-7.4	1.2e-13	-0.84	0.02	0.58	FALSE
14	METSIM	Adipose	EXOSC10	0.05	0.06	lasso	1	0.05	3.5e-08	7.0	7.0	2.7e-12	0.85	0.02	0.98	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	RP4-635E18.7	0.23	0.09	enet	24	0.24	3.8e-30	6.3	6.5	1.1e-10	0.71	0.02	0.98	FALSE
13	GTEx	Whole Blood	MTOR	0.16	0.06	enet	18	0.07	5.1e-07	7.7	6.4	1.4e-10	0.66	0.79	0.20	FALSE
3	GTEx	Adipose Subcutaneous	MASP2	0.10	0.06	lasso	2	0.03	8.8e-04	6.3	6.3	2.4e-10	0.69	0.51	0.27	FALSE
11	GTEx	Nerve Tibial	MASP2	0.14	0.07	lasso	5	0.09	1.2e-06	6.3	6.1	1.0e-09	0.68	0.35	0.56	FALSE