[Hub]/) : Traits : Whole body fat-free mass : ← →

chr1:21,680,408-24,216,118

Best TWAS P=1.11e-13 · Best GWAS P=2.17e-13 conditioned to 0.018

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HTR1D	0.24	0.12	lasso	4	0.12	1.2e-05	-6.9	7.4	1.1e-13	-0.76	0.04	0.95	TRUE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	WNT4	0.03	0.01	blup	72	0.02	3.8e-05	4.2	6.0	2.5e-09	-0.04	0.26	0.48	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	CDC42	0.07	0.02	lasso	6	0.04	5.7e-06	2.5	5.2	2.4e-07	0.01	0.08	0.91	TRUE
4	GTEx	Cells Transformed fibroblasts	LUZP1	0.09	0.09	lasso	4	0.08	2.8e-06	-7.2	7.3	3.9e-13	-1.00	0.01	0.99	FALSE
2	GTEx	Brain Cortex	LUZP1	0.23	0.14	lasso	5	0.10	7.8e-04	-7.2	7.3	4.0e-13	-1.00	0.02	0.81	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	HTR1D	0.10	0.07	enet	7	0.08	3.8e-05	-6.2	6.9	4.6e-12	-0.94	0.02	0.98	FALSE
8	GTEx	Testis	LUZP1	0.17	0.09	lasso	4	0.08	2.6e-04	-6.8	-6.8	1.0e-11	0.55	0.09	0.70	FALSE
14	The Cancer Genome Atlas	Rectum Adenocarcinoma	HTR1D	0.19	0.12	enet	11	0.13	7.3e-04	-7.3	6.8	1.4e-11	-0.94	0.01	0.90	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HTR1D	0.11	0.07	enet	21	0.09	1.1e-10	-5.4	6.3	3.6e-10	-0.78	0.48	0.52	FALSE
6	GTEx	Muscle Skeletal	LUZP1	0.07	0.08	enet	14	0.08	3.5e-08	3.5	5.7	1.1e-08	-0.62	0.07	0.92	FALSE
3	GTEx	Brain Frontal Cortex BA9	RP1-184J9.2	0.38	0.00	lasso	11	0.00	4.3e-01	-6.8	5.7	1.4e-08	-0.54	0.05	0.18	FALSE
9	METSIM	Adipose	LUZP1	0.07	0.00	enet	30	0.01	1.1e-02	3.5	5.4	8.2e-08	-0.36	0.11	0.49	FALSE
7	GTEx	Skin Sun Exposed Lower leg	KDM1A	0.09	0.01	lasso	5	0.01	1.1e-01	-6.8	-5.3	1.2e-07	0.39	0.10	0.46	FALSE
5	GTEx	Esophagus Muscularis	RP1-184J9.2	0.07	0.08	enet	6	0.05	6.1e-04	-5.4	5.1	3.0e-07	-0.72	0.37	0.49	FALSE