TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
←
→
chr2:70,715,824-72,356,449
Best TWAS P=7.99e-15 · Best GWAS P=1.31e-15 conditioned to 1
70.8M
71M
71.2M
71.4M
71.6M
71.8M
72M
72.2M
72.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
ZNF638
0.25
0.07
enet
20
0.10
5.2e-06
7.9
7.8
8.0e-15
0.98
0.01
0.99
TRUE
5
The Cancer Genome Atlas
Thyroid Carcinoma
ZNF638
0.08
0.05
enet
10
0.05
5.6e-06
8.0
7.4
9.8e-14
0.88
0.01
0.99
FALSE
2
GTEx
Artery Tibial
ZNF638
0.10
0.06
enet
13
0.07
2.4e-06
8.0
7.1
1.4e-12
0.88
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Esophageal Carcinoma
ZNF638
0.12
0.08
lasso
1
0.07
2.2e-03
5.3
5.3
1.0e-07
0.76
0.05
0.66
FALSE
3
METSIM
Adipose
PAIP2B
0.05
0.03
lasso
9
0.03
5.0e-05
5.8
5.3
1.2e-07
0.75
0.64
0.29
FALSE