TWAS
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Traits
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Traits
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Whole body fat-free mass
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chr2:67,709,195-69,180,661
Best TWAS P=3.42e-10 · Best GWAS P=2.77e-10 conditioned to 1
67.8M
68M
68.2M
68.4M
68.6M
68.8M
69M
69.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
RP11-474G23.2
0.17
0.14
lasso
3
0.12
2.3e-09
-6.3
-6.3
3.4e-10
0.97
0
1.00
TRUE
1
GTEx
Artery Tibial
PPP3R1
0.25
0.22
lasso
4
0.26
5.4e-20
-6.3
-6.3
3.6e-10
0.95
0
1.00
FALSE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
WDR92
0.04
0.01
blup
49
0.01
7.9e-03
-6.3
-6.1
1.0e-09
0.49
0
0.94
FALSE