[Hub]/) : Traits : Whole body fat-free mass : ← →

chr4:16,922,182-18,507,692

Best TWAS P=3.42e-58 · Best GWAS P=6.76e-53 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-14.3	16.1	3.4e-58	-0.81	0.05	0.80	TRUE
19	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-13.7	13.0	7.3e-39	-0.83	0.03	0.89	TRUE
4	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	10.6	11.8	2.2e-32	-0.36	1.00	0.00	TRUE
12	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	10.3	11.2	2.6e-29	-0.35	0.64	0.04	TRUE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	NCAPG	0.06	0.02	blup	34	0.04	1.0e-05	-13.8	-8.9	7.2e-19	0.68	0.03	0.75	TRUE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	NCAPG	0.03	0.04	enet	5	0.04	8.1e-09	-0.6	-5.5	4.3e-08	0.55	0.94	0.05	TRUE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	10.6	15.0	7.2e-51	-0.64	0.07	0.83	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	10.4	14.4	7.3e-47	-0.65	0.14	0.79	FALSE
14	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	9.2	14.3	1.4e-46	-0.66	0.06	0.52	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-13.8	-13.8	3.5e-43	0.88	0.03	0.57	FALSE
6	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-13.6	13.5	1.9e-41	-0.76	0.04	0.56	FALSE
16	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	9.2	13.5	2.0e-41	-0.54	0.17	0.71	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	9.2	13.4	7.3e-41	-0.58	0.27	0.23	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-13.7	-13.4	9.0e-41	0.84	0.68	0.32	FALSE
5	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	9.2	12.2	2.6e-34	-0.52	0.16	0.61	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-13.8	-12.2	3.8e-34	0.84	0.01	0.98	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-12.5	-11.5	1.5e-30	0.76	0.01	0.75	FALSE
15	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	10.4	11.4	4.9e-30	-0.26	0.19	0.04	FALSE
20	YFS	Blood	DCAF16	0.02	0.02	lasso	1	0.01	1.1e-04	10.6	10.6	3.8e-26	-0.25	0.84	0.04	FALSE
10	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	9.2	10.5	5.8e-26	-0.37	0.99	0.01	FALSE
13	GTEx	Skin Sun Exposed Lower leg	DCAF16	0.14	0.12	enet	14	0.12	5.4e-10	9.2	10.4	3.6e-25	-0.28	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	9.2	10.4	4.1e-25	-0.35	0.27	0.50	FALSE
8	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	9.2	9.8	8.1e-23	-0.37	0.13	0.41	FALSE
7	GTEx	Breast Mammary Tissue (Female)	DCAF16	0.16	0.13	lasso	2	0.06	7.8e-03	9.2	9.3	1.3e-20	-0.27	0.06	0.08	FALSE
11	GTEx	Pituitary	DCAF16	0.27	0.20	enet	15	0.19	1.3e-05	9.2	9.3	1.6e-20	-0.38	0.07	0.36	FALSE
9	GTEx	Esophagus Muscularis	DCAF16	0.16	0.14	lasso	3	0.14	9.3e-09	9.2	9.0	2.5e-19	-0.27	0.99	0.00	FALSE
1	GTEx	Adipose Subcutaneous	DCAF16	0.21	0.15	lasso	3	0.17	5.1e-14	9.2	8.9	3.5e-19	-0.24	1.00	0.00	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	FAM184B	0.17	0.14	enet	31	0.18	5.1e-23	-5.1	-7.0	2.0e-12	0.26	1.00	0.00	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	MED28	0.02	0.01	bslmm	411	0.00	1.9e-01	-4.9	6.7	1.8e-11	-0.30	0.22	0.03	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FAM184B	0.02	0.03	lasso	2	0.02	2.6e-03	-5.1	-5.2	2.0e-07	0.16	0.24	0.03	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	LAP3	0.07	0.03	blup	36	0.06	5.3e-05	-3.2	-5.2	2.4e-07	0.15	0.03	0.96	FALSE