[Hub]/) : Traits : Whole body fat-free mass :

chr5:76,597,461-78,753,539

Best TWAS P=1.73e-22 · Best GWAS P=1.6e-21 conditioned to 0.0222

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Pituitary LHFPL2 0.38 0.02 lasso 9 0.04 4.0e-02 0.62 -5.2 2.2e-07 0.50 0.04 0.49 FALSE
2 GTEx Testis LHFPL2 0.18 -0.01 enet 21 0.10 2.1e-05 4.23 5.7 1.5e-08 -0.26 0.11 0.15 FALSE
3 METSIM Adipose AP3B1 0.07 0.01 blup 556 0.02 2.4e-04 4.60 -6.8 8.4e-12 0.54 0.10 0.78 FALSE
4 YFS Blood AP3B1 0.25 0.22 lasso 9 0.23 2.6e-74 6.27 -6.4 2.0e-10 0.30 1.00 0.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma AP3B1 0.02 0.00 blup 126 0.01 1.8e-02 -9.53 -9.8 1.7e-22 0.85 0.02 0.90 TRUE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma AP3B1 0.16 0.06 enet 18 0.09 2.2e-05 6.94 -7.2 4.3e-13 0.52 0.04 0.52 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AP3B1 0.08 0.01 enet 20 0.02 9.7e-04 -9.22 -6.8 9.8e-12 0.60 0.02 0.81 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma AP3B1 0.05 0.03 lasso 3 0.04 4.4e-05 6.94 -6.6 3.4e-11 0.38 0.43 0.26 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma AP3B1 0.05 0.02 blup 126 0.03 5.0e-04 7.11 -9.3 1.8e-20 0.81 0.02 0.91 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma AP3B1 0.11 0.06 lasso 2 0.05 1.3e-05 6.27 -5.8 8.0e-09 0.20 0.59 0.05 FALSE