Hub : Genes

LHFPL2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Muscle Skeletal 0.0535 0.0245 8.6e-03 -0.003 NA -0.003 NA -0.003 7.5e-01 NA 9.7e-01 NA 9.1e-01
2 GTEx Pituitary 0.3760 0.1140 4.3e-03 0.022 NA 0.028 NA 0.038 9.2e-02 NA 6.5e-02 NA 4.0e-02
3 GTEx Testis 0.1790 0.0740 4.8e-03 -0.006 NA 0.105 NA 0.065 8.9e-01 NA 2.1e-05 NA 7.9e-04
4 GTEx Thyroid 0.0820 0.0300 9.9e-04 0.088 NA 0.070 NA 0.080 2.8e-07 NA 4.7e-06 NA 1.0e-06
5 NTR Blood 0.0149 0.0068 4.2e-03 0.002 0.005 0.003 0.003 0.003 6.5e-02 8.5e-03 3.0e-02 2.6e-02 4.2e-02
6 YFS Blood 0.0577 0.0176 1.8e-09 0.023 0.033 0.036 0.034 0.035 3.3e-08 5.1e-11 7.6e-12 3.0e-11 1.0e-11
7 TCGA Lung Squamous Cell Carcinoma 0.0434 0.0221 6.1e-03 0.029 0.017 0.010 NA 0.021 2.8e-04 4.4e-03 2.2e-02 NA 1.7e-03
8 TCGA Thyroid Carcinoma 0.0580 0.0290 2.7e-03 0.059 0.019 0.031 NA 0.050 1.9e-06 4.8e-03 4.7e-04 NA 1.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.5 2.4 8.5 1.5 -0.7 -2.9 1.6 0.5 0.2 2.3 -0.1
Bipolar Disorder or Schizophrenia 3.3 8.1 21.5 3.2 -0.3 -4.6 3.3 2.0 1.5 4.0 -0.2
Depressed Affect (Nagel 2018) 0.4 0.7 2.1 -1.4 -0.4 0.5 -0.5 -1.0 -1.3 -0.6 0.4
Depression (Nagel 2018) 2.5 3.8 11.2 -2.2 -0.6 2.4 -2.0 -1.7 -3.3 0.1 -1.1
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.5 -1.3 0.8 -0.5 -0.6 -1.9 -1.1 1.0 -1.3
Neuroticism (Nagel 2018) 0.3 0.6 1.5 -1.2 -0.2 -0.2 -0.7 -1.1 -1.2 -0.6 0.1
Schizophrenia (2018) 3.0 6.2 13.1 2.9 -0.1 -3.6 3.0 2.2 1.8 3.3 -0.3
Schizophrenia vs Biploar Disorder 0.6 0.7 2.3 -0.7 0.6 1.5 -0.5 0.5 1.0 -1.1 0.3
Worry (Nagel 2018) 0.3 0.6 1.5 -0.3 0.2 -0.5 -0.6 -1.0 -1.2 0.7 -1.1
Alzheimer’s Disease (in mother) 1.0 1.2 2.3 -1.5 0.3 1.2 -1.3 -1.0 -1.4 -1.1 -0.4
Alzheimer’s Disease (in father) 0.9 1.0 2.0 -1.4 0.7 0.7 -1.2 -1.2 -1.2 -0.9 0.0
Alzheimer’s Disease (including proxy) 1.6 2.3 4.1 -2.0 0.6 1.7 -1.8 -1.4 -1.7 -1.6 -0.2
Crohns Disease (2017) 0.3 0.7 1.5 0.2 -0.1 -1.2 0.8 -0.2 -1.0 1.2 0.9
Irritable Bowel Disease (IBD) 0.4 0.9 2.7 0.8 -0.0 -1.6 1.3 -0.2 -0.5 1.2 0.7
Ulcerative Colitis (UC) 0.2 0.5 1.3 0.9 0.2 -1.2 1.1 -0.2 0.1 0.4 0.5
Major Depression (MDD) 1.1 1.4 8.0 0.8 -0.5 0.1 0.7 -0.1 -1.0 2.8 -0.8
Reaction Time 0.2 0.4 0.8 -0.5 -0.9 -0.4 -0.5 -0.7 -0.5 -0.9 0.5
Verbal and Numeric Reasoning (VNR) 0.4 1.0 3.0 -0.9 0.1 0.1 -0.5 -0.8 -0.7 1.7 -1.7
Breast Cancer 0.1 0.2 0.7 0.0 -0.9 -0.2 -0.0 -0.1 -0.5 -0.5 0.6
Ovarian Cancer 0.6 0.7 2.6 -0.3 0.5 -1.4 -0.2 0.5 -0.2 0.8 -1.6
Prostate Cancer 2.3 3.2 5.3 -2.2 1.6 -0.1 -2.3 -2.0 -2.2 -1.9 0.0
Age at First Birth 1.1 1.6 5.0 1.5 0.2 -1.9 1.2 0.4 -0.1 2.2 -0.6
Bipolar Disorder (2011) 1.7 1.7 6.0 0.9 0.3 -1.6 0.9 -1.2 -0.8 2.5 -1.0
Body Mass Index (BMI) (2010) 1.0 1.4 4.5 -1.1 -0.5 1.3 -1.5 -1.0 0.0 -2.1 -0.1
Coronary Artery Disease (CAD) 0.8 1.0 4.2 0.9 0.1 -2.0 0.7 0.1 -0.5 1.5 0.0
Crohns Disease (2012) 0.4 0.7 2.2 -0.7 -0.2 -0.2 -0.3 -0.3 -1.5 -0.7 1.3
Mean Putamen Volume 2.4 2.8 6.3 1.4 -1.0 0.1 1.6 2.1 2.3 -0.8 2.5
Fasting Glucose 3.4 4.1 11.3 -2.4 0.6 0.7 -2.4 -3.4 -2.4 -0.7 -1.7
HbA1C 1.2 1.4 2.9 0.7 -1.4 -0.3 0.2 1.4 0.9 -1.7 1.6
HDL Cholesterol 0.7 1.1 2.6 0.8 -0.6 -0.5 0.9 1.2 1.2 1.6 -1.2
LDL Cholesterol 0.1 0.1 0.3 0.0 0.3 -0.4 0.1 0.1 0.6 -0.1 -0.4
Lupus 1.5 2.2 4.3 1.5 -1.3 -0.4 1.9 2.1 1.3 1.7 0.8
Neuroticism (2016) 1.3 1.9 4.0 -2.0 0.3 1.4 -1.3 -0.5 -1.3 -2.0 1.4
Primary Biliary Cirrhosis 0.3 0.5 1.1 -0.7 0.3 0.8 -0.5 0.5 -0.4 -1.1 0.9
Rheumatoid Arthritis 0.4 0.5 1.5 0.1 -1.2 0.7 0.2 1.1 0.9 0.0 0.5
Schizophrenia (2014) 2.9 6.5 14.3 2.9 0.1 -3.8 3.2 2.2 2.2 2.9 0.5
Triglycerides 0.9 1.4 6.3 -0.3 0.1 0.7 -0.5 -0.2 0.1 -2.5 2.0
Type 2 Diabetes (T2D) (2012) 2.3 2.7 5.1 1.4 -1.3 0.5 1.0 2.1 2.2 -1.4 2.3
Ulcerative Colitis 0.1 0.2 1.2 0.4 0.4 -1.1 0.2 -0.4 -0.1 0.2 -0.1
Blood Eosinophil Count 0.3 2.7 10.6 1.0 0.3 -0.0 0.7 1.8 1.1 -2.1 3.3
Blood Platelet Count 9.8 114.2 190.4 13.2 -1.4 -5.6 13.0 13.8 12.9 0.8 13.4
Blood Red Count 0.2 2.4 8.0 0.5 1.4 1.4 0.1 2.8 2.5 -0.8 0.5
Blood White Count 0.3 2.2 6.5 -1.0 -1.6 0.9 -0.7 -1.0 -0.3 -2.5 2.2
Heel T-Score 0.3 2.2 5.1 1.2 0.7 -2.2 1.9 -1.7 -0.9 1.8 0.6
BMI 1.0 6.0 17.9 -1.8 -1.3 4.2 -2.1 0.5 -0.2 -3.9 2.4
Height 1.1 22.1 82.7 -4.0 -9.1 6.1 -3.9 1.2 -4.0 -2.7 1.0
Waist Hip Ratio (WHR) 0.3 1.2 3.1 1.0 1.8 0.3 0.8 0.9 1.4 -0.6 1.3
Systolic Blood Pressure 1.0 5.2 13.5 1.1 3.7 -2.6 1.4 -3.4 0.1 -0.9 2.5
Smoking Status 1.4 3.4 7.7 0.7 -0.2 1.6 0.9 1.7 2.6 -2.4 2.8
Allergy or Eczema 0.2 0.4 1.5 0.1 -0.7 0.5 0.0 -0.2 -0.1 1.1 -1.2
Cardiovascular Disease 1.4 4.5 9.6 -2.5 0.9 0.7 -2.1 -3.1 -2.4 -2.7 0.9
Hypothyroidism (self reported) 0.4 1.0 2.7 0.9 -1.3 0.3 0.7 1.7 1.4 0.3 0.0
Respiratory disease 0.5 1.2 5.3 -1.3 0.1 -0.3 -0.8 -1.0 -0.9 0.3 -2.3
Type 2 Diabetes (T2D) (2018) 0.3 0.5 2.8 -0.2 -1.7 -0.8 -0.1 -0.4 0.7 0.0 -0.0
Lung FEV1/FVC ratio 1.6 8.1 29.4 3.4 1.4 -0.1 2.7 1.8 2.8 -1.9 5.4
Lung FVC 0.6 3.2 13.4 1.5 -3.7 0.6 1.4 2.3 0.1 1.1 0.8
Neuroticism 0.9 2.1 5.4 -2.1 -0.2 0.1 -1.5 -2.3 -1.9 -0.7 -0.8
Chronotype (morning person) 0.7 1.5 7.2 0.9 0.4 -2.7 1.1 0.1 0.6 1.6 -0.3
Hair Pigment 0.2 4.6 9.4 2.7 -0.5 -2.7 3.1 1.3 2.2 2.2 0.8
Tanning 0.2 2.8 8.1 -1.5 -0.0 2.6 -1.5 -0.7 -0.9 -2.9 1.2
Hand grip strength (left) 0.2 0.6 3.6 0.7 -1.9 0.4 0.4 0.2 -0.3 0.6 0.5
Number of treatments/medications taken 1.0 1.8 4.5 -2.1 -0.7 0.2 -1.5 -1.8 -1.1 -1.8 -0.4
Average weekly spirits intake 1.5 1.9 4.0 -2.0 -0.8 1.5 -1.5 -1.6 -1.5 -0.8 -0.7
Sensitivity / hurt feelings 0.7 1.2 2.7 -1.2 -1.6 1.6 -0.8 -0.9 -0.8 -1.0 -0.0
Frequency of depressed mood in last 2 weeks 3.6 5.0 9.4 -3.0 -1.4 2.5 -2.4 -2.5 -3.1 -1.0 -0.7
Hearing difficulty/problems: Yes 2.5 3.9 6.8 2.5 -0.5 -1.2 2.6 2.3 1.6 2.3 1.7
Relative age of first facial hair 0.6 1.2 5.3 -0.1 0.3 -0.7 -0.1 0.1 -0.6 1.8 -2.3
Other serious medical condition/disability diagnosed by doctor 1.1 1.5 3.5 -1.3 -1.2 0.5 -1.1 -0.4 -1.9 -1.4 1.3
Ever used hormone-replacement therapy (HRT) 2.2 2.7 6.5 1.7 -0.4 -0.1 2.1 2.5 2.5 0.3 1.2
Ever had hysterectomy (womb removed) 0.5 0.6 2.5 0.1 -0.9 0.4 -0.0 -0.4 -0.1 1.0 -1.6
Systolic blood pressure, automated reading 1.0 2.8 5.7 0.4 2.4 -1.7 0.8 -2.1 0.4 -1.7 2.2
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 1.4 -0.9 0.5 0.3 -0.6 -1.2 -0.2 -0.0 -1.1
Angina 2.6 3.4 7.3 2.0 0.8 -0.8 2.2 2.7 2.3 0.9 1.9
Medication for hormone replacement therapy 0.2 0.3 0.8 -0.1 -0.9 0.2 0.2 -0.3 0.0 0.6 -0.8
Vitamin and mineral supplements 2.8 3.8 7.0 2.2 1.3 -1.7 2.3 2.5 2.6 0.1 1.5
Supplements: Zinc 4.8 5.2 10.2 -2.4 -0.9 1.6 -3.2 -2.2 -3.2 0.2 -2.7
Medication: Co-codamol 5.1 5.9 11.9 -2.9 0.4 -0.5 -2.9 -3.4 -3.4 -0.4 -2.5
Medication: Metformin 0.6 0.8 4.1 -0.1 -2.0 0.1 -0.0 0.4 1.5 -0.1 -0.4
Diabetes (father) 0.5 0.6 1.7 0.7 -0.6 0.7 0.6 1.0 1.3 0.6 -0.1
Diabetes (mother) 0.8 1.0 2.5 -0.9 -1.2 1.6 -0.9 -0.6 -1.3 0.3 -0.7
Severe depression (siblings) 0.2 0.2 0.5 0.2 0.7 -0.3 0.3 0.4 -0.4 0.3 0.7
Pack years adult smoking proportion 0.4 0.6 2.8 -0.7 -1.7 0.6 -0.5 -0.1 -0.7 -0.1 -0.2
Impedance of leg (right) 0.2 1.2 4.5 0.2 0.2 -1.2 0.4 -0.3 -0.6 2.1 -1.6
Leg fat-free mass (left) 2.0 10.6 27.8 -2.9 -4.8 5.3 -3.1 0.0 -1.4 -3.7 0.9
Trunk fat percentage 1.0 4.2 11.0 -1.8 -3.0 3.3 -1.4 1.3 -0.0 -2.4 1.0
Hand grip strength (right) 0.2 0.7 2.4 -0.2 -1.5 1.5 -0.2 -0.1 -0.6 -0.4 0.1
Townsend deprivation index at recruitment 0.3 0.4 1.1 0.1 0.8 -0.8 0.2 0.5 1.0 0.4 -0.8
Current tobacco smoking 0.6 0.9 2.3 0.5 1.5 0.7 0.5 1.3 1.3 -0.2 0.8
Average weekly fortified wine intake 0.8 0.9 2.9 0.1 -1.1 1.0 0.4 1.7 0.1 -0.3 1.4
Maternal smoking around birth 1.1 1.6 3.8 -1.2 -1.2 -0.9 -1.1 -1.3 -1.0 1.1 -1.9
Fed-up feelings 1.9 3.5 8.8 -2.4 -0.2 1.3 -2.1 -3.0 -2.2 -1.4 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 3.4 4.6 15.0 -2.3 -0.3 1.6 -2.2 -2.7 -3.9 -0.2 -1.2
Relative age voice broke 0.5 0.8 3.0 -1.0 0.8 0.5 -0.8 -0.7 -0.4 0.4 -1.7
Taking other prescription medications 0.8 1.3 3.1 -1.7 -0.2 0.1 -1.1 -1.6 -1.7 -0.3 -0.7
Age when periods started (menarche) 2.0 4.8 9.0 2.7 2.3 -2.3 2.3 1.5 2.0 3.0 -0.8
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.3 0.6 -1.5 0.2 0.5 0.5 0.4 1.4 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 4.0 1.9 -1.0 -1.6 2.0 0.9 1.3 1.9 0.4
Tinnitus: Yes, but not now, but have in the past 3.2 3.4 6.5 2.0 -1.0 -2.5 2.5 1.1 1.9 1.2 1.7
Qualifications: CSEs or equivalent 0.4 0.5 1.1 -0.6 0.7 1.0 -0.6 -0.7 -0.5 -1.1 0.2
Serious illness, injury or assault to yourself 0.4 0.5 1.6 0.7 1.2 -0.6 0.5 0.5 0.1 0.3 0.9
High blood pressure 1.8 5.2 13.0 -2.5 1.1 0.0 -2.0 -3.6 -3.0 -2.6 0.7
Hayfever, allergic rhinitis or eczema 0.2 0.5 2.0 0.5 -0.7 0.0 0.4 -0.1 0.4 1.4 -1.0
Multivitamins +/- minerals 4.4 5.6 8.8 -2.7 -2.4 2.7 -2.7 -2.6 -3.0 -0.3 -1.5
Stomach or abdominal pain in last month 1.2 1.5 7.1 1.2 0.7 -1.3 1.1 0.2 -0.4 2.7 -0.0
Supplements: Glucosamine 2.5 3.2 6.2 -2.5 -0.7 1.8 -2.2 -1.6 -1.0 -2.5 -1.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.4 0.6 0.4 -1.6 0.8 0.1 -0.7 1.3 -0.4
Medication: Atenolol 2.0 2.4 7.1 -1.2 -0.6 1.1 -1.6 -2.7 -2.5 -0.5 -0.1
Medication: Levothyroxine sodium 0.5 0.8 1.9 1.4 -0.6 0.4 1.0 1.1 0.9 1.1 -0.3
Sitting height 1.7 12.3 51.7 -2.5 -7.2 3.4 -2.5 -1.9 -4.1 -0.6 -1.2
Chronic bronchitis/emphysema (father) 1.0 1.2 3.4 0.3 -0.8 -1.8 0.3 -1.5 -1.3 1.1 -0.7
High blood pressure (mother) 0.7 1.0 1.8 -0.9 1.3 0.3 -0.7 -1.3 -0.9 -1.3 0.6
Body mass index (BMI) 0.7 3.1 9.6 -1.3 -1.3 3.1 -1.2 0.8 0.7 -2.8 1.1
Impedance of leg (left) 0.2 1.1 3.2 0.6 0.5 -1.7 0.8 -0.2 -0.1 1.8 -1.2
Leg predicted mass (left) 2.0 10.6 28.0 -2.9 -4.8 5.3 -3.1 0.0 -1.3 -3.6 0.8
Trunk fat mass 1.7 7.4 20.0 -2.5 -3.9 4.5 -2.2 1.1 -0.6 -3.2 1.0
Waist circumference 1.3 4.8 15.6 -1.9 -2.1 3.9 -1.8 1.1 0.1 -3.0 1.0
Number of incorrect matches in round 0.8 1.3 6.0 0.1 -0.9 0.4 0.5 -0.9 -1.1 2.4 -0.9
Past tobacco smoking 0.8 1.5 3.7 0.2 1.0 -0.9 -0.4 -1.1 -1.2 1.9 -1.9
Alcohol usually taken with meals 0.5 0.8 2.8 -1.0 -0.6 1.0 -1.1 0.2 -0.3 -1.7 -0.0
Nervous feelings 0.2 0.3 2.2 0.2 0.4 0.1 0.1 -0.3 -0.2 1.5 -0.4
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.5 4.5 -1.5 -0.6 1.3 -1.2 -1.1 -2.1 0.1 -0.8
Hearing difficulty/problems with background noise 1.0 1.6 3.3 1.2 -0.6 -0.2 1.3 1.8 1.8 0.4 1.7
Hair/balding pattern: Pattern 2 0.2 0.2 0.9 -0.5 -0.4 0.9 -0.6 -0.0 -0.2 -0.3 -0.3
Had menopause 0.7 0.9 2.0 -1.3 -1.4 1.1 -0.8 0.1 -0.6 -1.1 -0.0
Had other major operations 1.0 1.2 3.8 -1.4 -0.7 0.6 -1.1 -1.0 -1.9 -0.6 0.1
Forced vital capacity (FVC) 2.3 9.1 49.9 -1.1 -7.1 3.8 -1.4 1.0 -1.7 -0.0 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.1 1.1 -0.3 -1.4 1.2 0.6 1.1 0.7 0.4
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.7 1.1 -0.7 -0.1 1.3 0.2 0.6 0.7 0.8
Qualifications: None of the above 0.1 0.2 0.4 -0.4 0.6 -0.4 -0.1 -0.4 -0.6 0.3 -0.5
Financial difficulties in last 2 years 0.6 0.7 2.6 -0.7 1.2 0.2 -0.6 -0.6 -0.4 -1.6 0.7
Mouth/teeth dental problems 0.1 0.2 0.3 0.4 -0.5 -0.0 0.4 -0.3 0.5 0.5 -0.3
Heart attack 0.6 0.8 2.5 1.2 -1.6 0.0 0.8 0.6 0.5 0.3 0.9
Allergy 0.5 1.2 4.3 -0.4 0.4 0.6 -0.7 -0.1 -0.5 -1.9 2.1
Pain all over the body in last month 1.5 1.6 3.9 1.4 0.8 -0.7 1.4 1.2 2.0 -0.7 1.6
Diabetes (self-reported) 0.3 0.5 1.4 -0.1 -0.6 -1.2 0.2 0.1 1.0 0.3 -0.8
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 1.2 0.1 0.4 0.4 -0.2 -0.4 0.2 0.4 -1.1
Medication: Ramipril 0.3 0.4 1.6 0.6 -0.2 -0.7 0.5 0.4 0.3 0.2 1.3
Medication: Simvastatin 0.3 0.4 1.3 -0.2 0.3 -0.8 0.1 -0.1 0.4 -1.0 1.1
Fluid intelligence score 0.4 0.9 1.9 -1.0 -0.5 -0.2 -0.7 -0.8 -0.8 1.3 -1.4
Illnesses of siblings 1.0 1.4 3.4 1.1 1.6 -0.3 0.3 1.8 1.8 0.7 -0.2
Neuroticism score 0.4 0.9 3.1 -1.2 -0.4 -0.3 -0.7 -1.7 -1.1 0.3 -0.7
Weight 2.2 10.9 30.1 -3.1 -4.7 5.5 -3.1 0.4 -1.1 -3.8 0.7
Impedance of arm (right) 0.5 2.1 10.0 0.7 -1.1 -1.5 1.0 0.7 -0.3 3.2 -1.2
Arm fat percentage (right) 0.6 2.5 8.5 -1.1 -1.6 2.9 -0.7 1.5 0.7 -1.8 1.1
Trunk fat-free mass 2.3 13.5 32.8 -3.3 -5.3 5.7 -3.7 -0.5 -1.8 -4.3 0.7
Hip circumference 1.6 7.1 17.8 -2.5 -4.0 4.2 -2.4 0.7 -0.9 -3.0 0.7
Time employed in main current job 2.3 2.7 4.1 1.9 -0.4 -1.9 2.0 2.0 1.3 1.5 1.5
Alcohol intake versus 10 years previously 1.0 1.5 6.6 1.0 0.1 -0.8 1.3 0.3 0.3 2.6 -1.2
Father’s age at death 1.2 1.6 3.2 -1.8 -0.6 1.3 -1.3 -1.2 -1.7 0.0 -1.2
Worrier / anxious feelings 1.3 2.5 10.8 0.8 -0.6 -2.1 0.8 -0.3 -0.6 3.3 -1.6
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 6.1 -1.9 -0.4 1.0 -1.0 -1.8 -2.5 0.6 -1.3
Falls in the last year 0.3 0.4 1.4 0.1 -0.3 0.0 0.2 -0.9 -0.6 -0.9 1.2
Hair/balding pattern: Pattern 3 0.5 0.7 1.8 0.7 -1.2 -1.0 0.9 -0.1 0.1 1.3 0.3
Number of live births 0.9 1.3 3.1 1.4 -0.3 -0.6 1.4 1.5 0.5 1.8 0.4
Forced expiratory volume in 1-second (FEV1) 1.7 5.9 32.2 -0.3 -5.7 3.4 -0.7 1.3 -0.8 -0.4 0.5
Pulse rate 1.0 1.7 7.5 -0.8 0.3 2.7 -0.8 0.9 0.2 0.8 -1.8
Happiness 0.2 0.3 1.4 -0.1 -0.3 0.3 -0.4 -0.4 -0.3 -1.2 0.6
Noisy workplace 0.3 0.4 1.0 -0.1 -0.5 0.7 0.3 0.8 0.4 0.9 -1.0
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.2 0.9 0.2 -0.9 0.8 0.8 0.1 1.1 0.4
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 1.7 -0.3 -1.3 1.3 -0.0 0.3 0.1 1.3 -1.3
Mouth/teeth dental problems: Dentures 1.3 2.3 4.5 -1.4 -2.1 1.9 -1.6 -0.1 -0.8 -2.1 0.5
Asthma 0.5 1.1 3.6 -0.9 1.7 -0.7 -0.4 -0.8 -0.2 -0.3 -1.9
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 0.8 -0.0 -0.9 0.4 0.1 0.1 0.8 -0.8 0.1
Medication: Cholesterol lowering 0.2 0.3 1.0 0.1 -0.3 -1.0 0.0 -0.5 -0.8 0.6 0.7
Depression (self-reported) 0.2 0.2 0.5 0.0 -0.6 0.4 0.5 -0.0 0.4 -0.7 0.4
Medication: Lansoprazole 0.3 0.4 1.4 1.2 -0.4 -0.5 0.7 0.4 -0.4 0.4 0.7
Prospective memory result 0.4 0.4 1.2 0.6 0.7 0.2 0.1 0.5 1.1 -0.7 0.8
Lung cancer (father) 3.0 3.5 9.8 -1.8 0.1 -0.2 -1.7 -2.3 -3.1 0.7 -2.5
Illnesses of mother 1.4 1.7 3.1 1.8 -0.4 -1.7 1.3 1.1 1.6 1.5 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.0 30.1 -0.0 -5.5 2.9 -0.4 1.0 -0.5 -0.1 0.6
Pulse wave Arterial Stiffness index 0.6 0.7 2.3 0.1 0.2 -0.0 0.3 1.5 1.3 -0.4 1.1
Impedance of arm (left) 0.5 2.3 10.0 0.1 -1.2 -1.2 0.5 0.3 -0.9 3.2 -2.1
Arm fat mass (right) 1.5 6.0 17.8 -1.9 -3.3 4.2 -1.7 1.3 0.4 -3.1 1.1
Trunk predicted mass 2.4 13.5 32.9 -3.4 -5.2 5.7 -3.7 -0.5 -1.8 -4.3 0.7
Standing height 1.8 18.1 59.7 -3.8 -7.7 5.6 -4.1 -0.5 -3.6 -3.0 -0.4
Length of working week for main job 0.5 0.5 1.5 0.7 0.2 -0.6 0.7 0.8 0.1 1.2 0.9
Exposure to tobacco smoke at home 0.5 0.6 1.6 0.1 -1.2 -0.9 0.2 0.5 -0.5 1.1 -0.6
Breastfed as a baby 0.5 0.6 2.1 -0.6 0.7 0.8 -0.6 0.4 0.7 -1.5 0.7
Tense / ‘highly strung’ 0.8 1.3 2.7 -1.0 0.5 0.8 -1.3 -1.2 -1.6 -1.6 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 3.0 -1.0 -1.7 1.2 -0.5 -0.6 -1.0 1.2 -1.7
Hair/balding pattern: Pattern 4 1.3 3.2 8.7 -2.0 0.3 0.8 -2.2 -2.9 -2.0 -1.0 -1.6
Birth weight of first child 0.2 0.4 1.7 0.0 -0.7 0.4 0.2 1.3 -0.3 1.0 -0.4
Peak expiratory flow (PEF) 1.1 2.6 5.2 2.0 -1.6 0.2 1.8 2.3 0.8 1.1 2.0
Pulse wave reflection index 1.5 1.9 5.7 1.0 1.5 -1.4 1.0 1.0 1.1 -1.1 2.4
Ever highly irritable/argumentative for 2 days 1.0 1.2 4.6 0.5 -1.5 -0.5 0.9 0.3 2.1 -1.0 0.7
Loud music exposure frequency 0.6 0.6 2.6 0.5 -0.4 -0.4 1.2 0.4 0.1 -0.2 1.6
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 3.2 -0.7 0.7 -0.2 -0.2 -0.5 -0.2 -1.6 1.8
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 1.5 1.0 0.2 -1.1 1.1 1.2 0.3 1.1 0.1
Blood clot in the leg (DVT) 2.8 3.7 11.3 -2.4 -1.1 0.3 -1.9 -1.6 -1.9 1.0 -3.4
Medication: Paracetamol 1.0 1.7 4.4 -1.7 0.8 -0.7 -1.4 -2.1 -0.4 -1.0 -1.4
Headache pain in last month 2.9 5.0 11.0 -2.7 -1.4 1.2 -2.3 -2.2 -2.7 0.8 -3.3
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 2.9 1.6 0.2 0.3 1.6 1.5 1.7 1.0 -0.1
Glaucoma (self-reported) 3.2 3.7 9.9 -2.6 0.8 2.0 -2.7 -1.1 -0.8 -3.1 -0.1
Gout (self-reported) 1.0 1.3 3.7 -1.5 -0.7 0.9 -1.9 -0.4 -1.2 -0.5 -1.2
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.6 -0.1 -0.7 0.8 -0.2 0.4 0.4 0.1 -0.7
Medication: Amlodipine 0.4 0.5 1.9 -0.6 -0.5 0.0 -0.5 -1.4 -0.8 0.2 -0.7
Medication: Ventolin 100micrograms inhaler 1.0 1.2 2.6 -1.2 -0.8 -0.5 -0.7 -1.4 -1.6 0.3 -1.5
Birth weight 0.5 1.1 3.4 0.5 -1.4 0.6 0.2 1.8 -0.0 1.2 -1.2
Chronic bronchitis/emphysema (mother) 0.2 0.2 0.8 -0.8 -0.1 0.9 -0.1 -0.1 -0.2 -0.6 0.2
High blood pressure (siblings) 1.0 1.4 4.6 -0.8 -1.5 -0.8 -0.2 -1.6 -2.1 -0.6 0.6
Forced vital capacity (FVC), Best measure 2.1 7.5 42.2 -1.1 -6.5 3.4 -1.2 0.6 -1.7 0.2 -0.8
Body fat percentage 0.9 3.6 11.7 -1.8 -2.1 3.4 -1.4 1.1 0.1 -2.4 0.7
Leg fat percentage (right) 0.8 2.9 10.2 -2.0 -0.9 3.2 -1.8 0.2 -0.3 -2.2 -0.1
Arm fat-free mass (right) 2.2 11.3 28.5 -3.0 -4.7 5.3 -3.2 0.0 -1.2 -4.3 0.9
Exposure to tobacco smoke outside home 0.7 1.0 3.5 -1.4 -1.9 -0.3 -0.9 -0.2 -0.6 -0.3 -0.9
Comparative body size at age 10 0.9 2.4 5.3 -1.9 -1.7 2.3 -1.9 0.3 -0.3 -1.9 -0.3
Number of full brothers 0.8 1.0 4.8 -0.2 0.4 0.6 -0.1 -0.4 0.2 1.6 -2.2
Worry too long after embarrassment 0.2 0.4 1.2 -1.1 0.2 0.4 -0.5 -0.9 -0.0 -0.8 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 0.8 -0.8 -0.8 0.3 -0.5 -0.1 -0.3 0.5 -0.9
Wheeze or whistling in the chest in last year 0.8 1.4 6.9 -1.0 2.6 0.6 -0.8 -0.8 -0.7 -1.0 -0.4
Number of children fathered 0.2 0.2 0.7 0.0 -0.1 -0.8 -0.3 0.4 -0.0 -0.8 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 2.4 1.0 0.1 -1.6 0.7 1.1 0.2 1.2 -0.7
Age at first live birth 0.6 1.1 2.6 -1.3 0.3 -0.1 -1.6 -1.0 -0.9 -1.5 -0.4
Pulse wave peak to peak time 0.6 0.6 1.8 -0.2 -0.7 0.2 -0.3 -1.4 -1.3 0.2 -0.9
Health satisfaction 0.9 1.2 1.9 -1.4 1.3 0.3 -1.0 -1.4 -1.2 -1.0 -0.9
Shortness of breath walking on level ground 3.3 3.9 8.6 -2.9 -0.4 2.5 -2.6 -1.5 -1.6 -1.9 -1.0
Qualifications: College or University degree 0.4 1.2 3.7 0.6 -1.9 0.1 -0.4 0.3 -0.5 1.7 -1.6
Eye problems/disorders: None of the above 1.3 1.5 4.4 -1.0 -0.3 0.3 -1.0 -0.9 -1.5 -2.1 1.4
Mouth/teeth dental problems: Loose teeth 0.7 0.8 1.9 -1.0 -0.2 0.3 -1.0 -1.4 -1.3 -0.9 0.4
Emphysema/chronic bronchitis 1.0 1.1 3.3 -1.0 -1.6 0.4 -0.7 -0.9 -1.0 0.4 -1.8
Medication for pain relief, constipation, heartburn 0.3 0.4 1.3 0.9 0.7 -0.2 0.5 0.5 -0.5 1.1 0.1
Neck or shoulder pain in last month 1.1 1.6 3.8 -1.7 0.7 0.7 -1.3 -1.7 -1.9 -0.4 -0.5
Medication: Blood pressure 2.0 3.6 7.4 -2.6 0.7 0.1 -2.6 -2.7 -2.4 -1.3 -0.4
Angina (self-reported) 2.0 2.6 5.9 1.8 0.9 -0.8 2.0 2.4 1.9 0.8 1.6
Migraine (self-reported) 0.8 1.0 2.4 -0.9 -1.1 1.6 -0.7 -0.3 -0.7 0.2 -1.5
Medication: Ibuprofen 0.3 0.3 1.1 0.3 -0.5 -0.1 0.3 0.4 1.0 -0.9 0.4
Medication: Allopurinol 0.8 1.1 2.7 -1.2 -0.8 0.7 -1.6 -0.5 -1.1 -0.1 -1.5
Medication: Omeprazole 0.4 0.5 0.9 -1.0 -0.3 0.5 -1.0 -0.3 -0.6 -0.9 -0.4
Medication: Seretide 50 evohaler 1.6 1.8 4.3 -1.9 -0.9 0.5 -1.5 -1.2 -0.9 -2.1 -1.0
Mean time to correctly identify matches 0.5 0.9 4.1 -0.2 0.0 -0.5 -0.1 -0.1 -0.1 -1.7 2.0
Heart disease (mother) 0.5 0.6 2.0 -0.5 -1.4 -0.3 -0.4 -0.2 -1.4 0.8 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.0 4.8 -1.0 2.2 0.7 -1.1 -0.7 0.0 -0.5 0.2
Whole body fat mass 1.6 6.8 19.9 -2.5 -3.3 4.5 -2.2 0.9 -0.5 -3.3 0.8
Leg fat mass (right) 1.3 4.9 16.0 -2.2 -2.1 4.0 -2.0 0.9 -0.1 -3.0 0.6
Arm predicted mass (right) 2.2 11.4 28.6 -3.2 -4.4 5.3 -3.5 -0.3 -1.5 -4.3 0.6
Pulse rate, automated reading 0.5 1.7 7.5 -1.0 -0.9 2.7 -1.0 0.7 0.4 -0.3 -1.6
Alcohol intake frequency. 1.0 2.3 9.8 -0.9 -0.2 -0.5 -1.0 -3.1 -1.7 0.9 -1.6
Comparative height size at age 10 2.4 13.0 39.6 -3.5 -6.3 4.7 -3.5 -0.7 -3.2 -2.8 0.2
Number of full sisters 1.5 1.8 3.2 -1.8 -0.3 0.6 -1.8 -1.6 -1.2 -1.0 -1.6
Suffer from ‘nerves’ 0.1 0.2 1.1 -0.1 1.0 0.3 -0.3 -0.4 -0.2 -0.1 0.3
Overall health rating 0.7 1.6 3.9 -1.8 0.3 0.4 -0.9 -1.6 -2.0 -1.3 0.2
Chest pain or discomfort 0.1 0.2 0.6 -0.2 0.5 0.4 -0.0 -0.5 -0.5 0.1 0.8
Had major operations 0.6 0.7 2.1 0.6 -0.8 -0.7 1.1 0.8 0.1 1.4 0.5
Age at last live birth 0.6 0.9 1.7 -1.1 1.3 -1.0 -1.1 -0.5 -0.7 -1.2 -0.1
Family relationship satisfaction 1.5 1.8 2.9 -1.2 -1.4 1.6 -1.6 -0.9 -1.3 -1.7 0.8
Leg pain on walking 0.8 1.0 2.5 -1.6 -0.0 1.4 -1.1 1.0 -0.7 -0.8 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 1.4 0.6 -0.4 -0.6 1.2 0.6 0.3 0.9 0.1
Commuting to job workplace: Car/motor vehicle 1.3 1.5 6.0 -1.1 -0.7 2.4 -1.7 0.0 -1.0 -0.4 -0.8
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.8 0.2 0.2 -0.4 -0.3 -0.5 -0.2 0.4 -0.9
Medication: Aspirin 2.0 2.7 6.8 0.5 -1.4 2.2 0.5 1.8 1.6 -1.4 2.6
Supplements: Vitamin C 0.6 0.8 3.0 -0.4 -0.1 -0.1 -0.5 -1.1 -0.7 1.0 -1.7
Knee pain experienced in last month 0.8 1.3 4.8 -1.4 0.3 2.2 -1.0 -0.1 -0.3 -1.4 0.3
Hypertension (Self-reported) 1.7 4.8 10.8 -2.5 1.5 0.0 -2.0 -3.3 -2.9 -2.5 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.1 0.9 -0.8 -0.3 0.7 -0.3 -0.8 1.1 0.3
Illnesses of father: Heart disease 0.8 1.0 3.3 1.2 0.0 -0.8 1.0 0.6 1.0 -0.7 1.8
Illnesses of siblings: Diabetes 1.6 1.9 3.4 -1.6 -1.6 0.7 -1.2 -1.8 -1.6 0.3 -1.6
Smoking status: Previous 0.9 1.4 4.1 -0.2 -0.6 1.3 0.1 0.7 0.6 -2.0 1.9
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.2 5.6 -1.8 -2.4 1.6 -1.8 -1.0 -0.7 -0.9 -0.8
Whole body fat-free mass 2.2 12.7 32.0 -3.1 -5.2 5.7 -3.4 -0.2 -1.5 -4.3 1.0
Leg fat-free mass (right) 1.7 9.3 23.5 -2.6 -4.6 4.8 -2.8 -0.0 -1.1 -3.6 1.0
Arm fat percentage (left) 0.7 2.7 9.7 -1.6 -1.8 3.1 -1.2 1.1 0.3 -1.9 0.4
Average weekly red wine intake 1.1 1.6 4.6 -1.0 -0.4 1.6 -1.5 0.6 -0.9 -2.1 0.9
Handedness (chirality/laterality): Left-handed 1.2 1.4 6.7 0.4 -2.6 -1.3 0.2 0.1 -0.9 1.3 0.1
Mood swings 0.3 0.5 1.4 -0.8 -1.2 -0.8 -0.1 -1.0 -0.6 0.4 -0.3
Loneliness, isolation 2.4 3.3 6.6 -2.1 0.2 2.6 -2.0 -1.9 -2.2 -1.7 -0.4
Long-standing illness, disability or infirmity 2.2 3.3 6.4 -2.5 -1.1 1.8 -2.2 -2.0 -2.0 -0.9 -1.5
Ever had bowel cancer screening 0.8 0.9 2.2 -1.5 -0.9 1.3 -0.9 0.0 -1.0 -0.8 0.1
Diabetes diagnosed by doctor 0.1 0.2 0.8 -0.3 -0.4 -0.5 -0.1 0.3 0.9 -0.2 -0.1
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 6.1 -0.2 2.5 0.2 -0.3 -0.9 -1.9 -0.8 0.7
Friendships satisfaction 1.7 2.1 8.6 -1.4 0.5 -0.1 -1.6 -1.6 -2.9 0.4 -0.7
Qualifications: nursing, teaching 0.2 0.3 1.0 0.2 -0.2 0.1 0.1 0.5 0.5 -0.8 1.0
Commuting to job workplace: Walk 1.0 1.0 2.1 1.0 0.9 -1.3 1.3 0.5 1.4 0.5 0.8
Eye problems/disorders: Cataract 2.8 3.2 11.7 1.5 -0.7 -1.8 1.6 0.8 1.2 3.4 -1.9
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.9 -0.4 1.4 -0.3 -0.5 -0.7 -0.1 0.5 -1.2
Medication for cholesterol 1.9 2.9 9.6 -1.3 0.5 0.9 -2.1 -2.0 -1.6 0.5 -3.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.3 -1.2 -0.7 -0.1 -0.7 -1.5 -0.7 -0.4 -0.7
Back pain experienced in last month 1.1 1.6 3.8 -1.7 -0.1 0.2 -1.5 -1.9 -1.0 -0.9 -1.4
Mineral and other dietary supplements 1.7 2.3 6.4 1.3 -0.3 -0.3 1.6 2.2 1.6 -0.5 2.5
Breast cancer (self-reported) 0.3 0.4 1.0 -0.5 -0.9 -0.4 -0.6 -1.0 -0.5 -0.7 0.3
Asthma (self-reported) 0.4 0.9 2.7 -0.6 1.6 -0.8 -0.2 -0.6 0.1 -0.1 -1.6
Osteoporosis (self-reported) 0.4 0.5 2.1 0.3 0.9 -1.4 0.2 -0.2 -0.7 0.6 -0.2
Osteoarthritis (self-reported) 0.4 0.6 3.0 -0.8 0.1 0.5 -0.7 0.1 -0.3 -1.7 0.3
Medication: Aspirin 2.1 2.7 4.8 0.6 -2.0 1.9 0.5 2.0 1.9 -0.9 2.2
Medication: Gliclazide 1.9 2.1 7.3 1.1 -0.8 1.9 0.4 2.7 1.6 0.0 1.0
Illnesses of father: None of the above (group 1) 0.2 0.2 1.1 -0.1 -0.2 0.8 0.1 1.0 0.3 0.4 0.1
Smoking status: Current 0.3 0.5 1.4 0.3 1.0 0.5 0.4 1.0 1.2 -0.1 0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 9.8 1.3 -3.1 0.9 0.8 0.7 -0.1 0.8 0.9
Whole body water mass 2.2 12.4 30.6 -3.1 -5.0 5.5 -3.4 -0.2 -1.4 -4.3 1.1
Leg predicted mass (right) 1.8 9.5 24.0 -2.6 -4.5 4.9 -2.9 -0.1 -1.1 -3.7 1.0
Arm fat mass (left) 1.4 5.6 17.9 -2.2 -3.1 4.2 -2.0 1.0 -0.2 -2.8 0.7
Number of self-reported non-cancer illnesses 0.5 0.9 2.5 -1.6 0.8 -0.2 -0.7 -0.9 -1.1 -1.3 -0.4
Average weekly champagne plus white wine intake 1.2 1.6 5.1 -1.2 -1.5 0.9 -1.3 -0.5 -1.1 -2.3 -0.0
Miserableness 0.2 0.4 2.0 -0.7 -0.2 0.3 0.2 -0.0 -0.1 -0.8 1.4
Guilty feelings 0.5 0.8 2.5 -0.7 -0.2 -0.5 -0.5 -1.6 -1.1 0.7 -1.0
Wears glasses or contact lenses 1.5 1.7 6.0 -1.6 -0.4 2.5 -1.4 -0.9 -1.2 -0.6 -0.6
Ever taken oral contraceptive pill 1.7 1.9 3.2 1.5 1.4 -0.6 1.6 1.2 1.8 1.7 0.7
Hearing aid user 0.8 0.9 2.4 -1.4 -0.4 1.1 -0.7 -0.5 -1.6 0.4 -0.7
Mother’s age at death 1.4 1.7 4.0 1.6 1.4 -1.5 1.4 1.0 0.0 2.0 -0.2
Financial situation satisfaction 0.6 0.7 5.7 -0.0 2.4 -0.2 -0.2 -0.3 0.3 0.0 -0.1
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.8 1.1 0.3 -0.6 1.3 0.1 1.3 0.7 0.3
Commuting to job workplace: Public transport 1.5 1.8 4.4 1.2 1.4 -1.7 1.6 0.5 2.1 0.6 0.4
Eye problems/disorders: Glaucoma 2.9 3.5 7.1 -2.5 1.2 1.4 -2.5 -1.8 -0.7 -2.7 -0.7
Medication: Blood pressure 0.7 1.4 5.3 0.8 -1.2 -1.1 1.4 0.6 0.3 -0.3 2.3
Pain type(s) experienced in last month: Hip pain 0.3 0.4 0.9 0.6 -0.0 -0.5 0.9 0.9 0.1 0.2 0.9
Supplements: Fish oil (including cod liver oil) 1.2 1.6 3.7 -1.2 0.7 0.8 -1.5 -1.9 -1.4 -0.3 -1.5
High cholesterol (Self-reported) 0.0 0.1 0.2 -0.3 -0.3 -0.2 -0.1 -0.5 0.2 -0.3 -0.1
Medication: Bendroflumethiazide 1.1 1.7 4.2 -1.5 0.5 1.1 -1.2 -2.1 -1.6 -1.2 0.1
Medication: Paracetamol 1.3 2.1 6.0 -1.8 0.9 -0.8 -1.4 -2.5 -0.3 -1.2 -1.6
Medication: Lisinopril 0.2 0.3 1.0 -0.4 -0.7 0.4 -0.3 -0.3 -0.4 -1.0 0.5
Medication: Atorvastatin 2.6 3.2 7.6 2.8 0.5 -1.2 2.4 1.6 0.9 1.9 1.9
Illnesses of father: High blood pressure 0.2 0.3 1.4 -0.2 0.4 0.3 -0.1 -1.2 0.1 -0.4 -0.8
Alcohol drinker status: Never 0.8 1.0 2.6 -0.7 0.4 -0.4 -1.4 -1.5 -0.3 -0.4 -1.6
Ever smoked 1.6 2.8 6.2 0.4 -0.8 0.3 1.0 2.1 2.3 -2.0 2.5
Basal metabolic rate 2.3 12.8 32.1 -3.2 -5.2 5.7 -3.4 -0.1 -1.4 -4.2 0.9
Leg fat percentage (left) 0.7 2.6 8.6 -1.8 -0.7 2.9 -1.5 0.4 0.1 -2.5 0.3
Arm fat-free mass (left) 2.4 12.0 29.8 -3.1 -4.4 5.5 -3.4 -0.2 -1.2 -4.7 1.3
Number of operations (self-reported) 0.7 1.1 2.6 0.5 -1.5 -0.3 1.1 1.5 0.3 0.4 1.6
Average weekly beer plus cider intake 1.1 1.6 4.9 1.3 0.4 -0.2 1.5 1.3 1.5 2.2 0.1
Irritability 0.2 0.3 1.1 -0.1 0.1 -0.6 -0.0 -0.0 0.5 -1.0 1.1
Risk taking 0.9 1.4 5.6 0.4 0.0 0.3 0.4 1.2 0.6 -1.8 2.4
Ever had prostate specific antigen (PSA) test 2.3 2.6 6.3 -2.2 -0.2 0.5 -2.5 -1.7 -1.3 -1.6 -1.4
Fractured/broken bones in last 5 years 0.6 0.8 3.3 0.4 1.8 -0.2 0.7 0.4 1.2 -0.1 0.8
Age started oral contraceptive pill 0.5 0.6 2.2 0.3 -0.9 -0.7 0.6 0.6 1.5 -0.6 0.2
Diastolic blood pressure, automated reading 1.3 3.9 9.9 1.7 1.6 -0.9 1.8 1.4 2.7 -1.5 3.2
Ever depressed for a whole week 1.5 1.9 4.2 1.9 0.2 -0.4 2.0 1.3 1.8 1.5 0.3
Unable to work because of sickness or disability 0.9 1.1 2.8 -1.3 0.6 1.0 -1.1 -1.7 -1.3 -0.2 -0.5
Commuting to job workplace: Cycle 1.5 1.9 6.3 -1.1 -0.9 -0.6 -1.3 -1.6 -1.3 0.5 -2.5
Myopia 1.5 2.2 4.7 -1.7 -1.1 1.3 -1.5 -1.8 -2.2 -0.5 -1.1
Vascular/heart problems diagnosed by doctor 1.1 3.1 6.5 1.7 -0.9 0.5 1.1 2.5 2.2 2.5 -1.5
Cholesterol lowering medication 1.3 1.8 4.6 1.5 0.4 -0.7 1.8 2.1 1.6 0.6 1.2
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.0 -0.6 0.2 0.5 -0.7 -0.1 -0.3 -1.0 -0.2
Pain experienced in last month 1.5 2.4 4.1 2.0 -0.3 -1.7 2.0 1.7 1.3 1.4 1.3
Supplements: Calcium 2.5 2.8 5.6 -2.0 -0.0 1.0 -2.4 -2.1 -2.0 -1.5 -0.9
Basal cell carcinoma (self-reported) 0.4 0.4 1.1 -0.5 -0.7 -1.1 -0.6 -0.7 -0.8 -0.1 0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.6 1.3 -1.6 -0.0 0.8 0.5 0.5 0.6 0.7
Deep venous thrombosis (DVT) (self-reported) 2.8 3.6 10.2 -2.4 -1.3 0.5 -1.9 -1.7 -1.9 0.9 -3.2
Heart disease (siblings) 0.3 0.4 1.4 0.4 -1.2 0.1 0.7 0.1 -0.4 0.6 -0.4
Alcohol drinker status: Previous 0.8 0.9 4.2 -0.6 0.7 -0.3 -0.7 -2.0 -1.3 -0.2 -0.1
Pack years of smoking 0.3 0.5 3.1 -0.5 -1.8 0.3 -0.3 0.2 -0.5 -0.2 -0.0
Impedance of whole body 0.4 2.1 9.3 0.7 -0.3 -1.6 1.0 0.3 -0.4 3.1 -1.7
Leg fat mass (left) 1.3 5.1 16.0 -2.2 -2.2 4.0 -2.0 0.8 -0.1 -3.2 0.8
Arm predicted mass (left) 2.1 10.9 28.4 -2.8 -4.6 5.3 -3.1 0.1 -1.0 -4.2 1.2