Hub : Genes

LHFPL2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.0535	0.0245	8.6e-03	-0.003	NA	-0.003	NA	-0.003	7.5e-01	NA	9.7e-01	NA	9.1e-01
2	GTEx	Pituitary	0.3760	0.1140	4.3e-03	0.022	NA	0.028	NA	0.038	9.2e-02	NA	6.5e-02	NA	4.0e-02
3	GTEx	Testis	0.1790	0.0740	4.8e-03	-0.006	NA	0.105	NA	0.065	8.9e-01	NA	2.1e-05	NA	7.9e-04
4	GTEx	Thyroid	0.0820	0.0300	9.9e-04	0.088	NA	0.070	NA	0.080	2.8e-07	NA	4.7e-06	NA	1.0e-06
5	NTR	Blood	0.0149	0.0068	4.2e-03	0.002	0.005	0.003	0.003	0.003	6.5e-02	8.5e-03	3.0e-02	2.6e-02	4.2e-02
6	YFS	Blood	0.0577	0.0176	1.8e-09	0.023	0.033	0.036	0.034	0.035	3.3e-08	5.1e-11	7.6e-12	3.0e-11	1.0e-11
7	TCGA	Lung Squamous Cell Carcinoma	0.0434	0.0221	6.1e-03	0.029	0.017	0.010	NA	0.021	2.8e-04	4.4e-03	2.2e-02	NA	1.7e-03
8	TCGA	Thyroid Carcinoma	0.0580	0.0290	2.7e-03	0.059	0.019	0.031	NA	0.050	1.9e-06	4.8e-03	4.7e-04	NA	1.2e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.5	2.4	8.5	1.5	-0.7	-2.9	1.6	0.5	0.2	2.3	-0.1
Bipolar Disorder or Schizophrenia	3.3	8.1	21.5	3.2	-0.3	-4.6	3.3	2.0	1.5	4.0	-0.2
Depressed Affect (Nagel 2018)	0.4	0.7	2.1	-1.4	-0.4	0.5	-0.5	-1.0	-1.3	-0.6	0.4
Depression (Nagel 2018)	2.5	3.8	11.2	-2.2	-0.6	2.4	-2.0	-1.7	-3.3	0.1	-1.1
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.5	-1.3	0.8	-0.5	-0.6	-1.9	-1.1	1.0	-1.3
Neuroticism (Nagel 2018)	0.3	0.6	1.5	-1.2	-0.2	-0.2	-0.7	-1.1	-1.2	-0.6	0.1
Schizophrenia (2018)	3.0	6.2	13.1	2.9	-0.1	-3.6	3.0	2.2	1.8	3.3	-0.3
Schizophrenia vs Biploar Disorder	0.6	0.7	2.3	-0.7	0.6	1.5	-0.5	0.5	1.0	-1.1	0.3
Worry (Nagel 2018)	0.3	0.6	1.5	-0.3	0.2	-0.5	-0.6	-1.0	-1.2	0.7	-1.1
Alzheimer’s Disease (in mother)	1.0	1.2	2.3	-1.5	0.3	1.2	-1.3	-1.0	-1.4	-1.1	-0.4
Alzheimer’s Disease (in father)	0.9	1.0	2.0	-1.4	0.7	0.7	-1.2	-1.2	-1.2	-0.9	0.0
Alzheimer’s Disease (including proxy)	1.6	2.3	4.1	-2.0	0.6	1.7	-1.8	-1.4	-1.7	-1.6	-0.2
Crohns Disease (2017)	0.3	0.7	1.5	0.2	-0.1	-1.2	0.8	-0.2	-1.0	1.2	0.9
Irritable Bowel Disease (IBD)	0.4	0.9	2.7	0.8	-0.0	-1.6	1.3	-0.2	-0.5	1.2	0.7
Ulcerative Colitis (UC)	0.2	0.5	1.3	0.9	0.2	-1.2	1.1	-0.2	0.1	0.4	0.5
Major Depression (MDD)	1.1	1.4	8.0	0.8	-0.5	0.1	0.7	-0.1	-1.0	2.8	-0.8
Reaction Time	0.2	0.4	0.8	-0.5	-0.9	-0.4	-0.5	-0.7	-0.5	-0.9	0.5
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.0	-0.9	0.1	0.1	-0.5	-0.8	-0.7	1.7	-1.7
Breast Cancer	0.1	0.2	0.7	0.0	-0.9	-0.2	-0.0	-0.1	-0.5	-0.5	0.6
Ovarian Cancer	0.6	0.7	2.6	-0.3	0.5	-1.4	-0.2	0.5	-0.2	0.8	-1.6
Prostate Cancer	2.3	3.2	5.3	-2.2	1.6	-0.1	-2.3	-2.0	-2.2	-1.9	0.0
Age at First Birth	1.1	1.6	5.0	1.5	0.2	-1.9	1.2	0.4	-0.1	2.2	-0.6
Bipolar Disorder (2011)	1.7	1.7	6.0	0.9	0.3	-1.6	0.9	-1.2	-0.8	2.5	-1.0
Body Mass Index (BMI) (2010)	1.0	1.4	4.5	-1.1	-0.5	1.3	-1.5	-1.0	0.0	-2.1	-0.1
Coronary Artery Disease (CAD)	0.8	1.0	4.2	0.9	0.1	-2.0	0.7	0.1	-0.5	1.5	0.0
Crohns Disease (2012)	0.4	0.7	2.2	-0.7	-0.2	-0.2	-0.3	-0.3	-1.5	-0.7	1.3
Mean Putamen Volume	2.4	2.8	6.3	1.4	-1.0	0.1	1.6	2.1	2.3	-0.8	2.5
Fasting Glucose	3.4	4.1	11.3	-2.4	0.6	0.7	-2.4	-3.4	-2.4	-0.7	-1.7
HbA1C	1.2	1.4	2.9	0.7	-1.4	-0.3	0.2	1.4	0.9	-1.7	1.6
HDL Cholesterol	0.7	1.1	2.6	0.8	-0.6	-0.5	0.9	1.2	1.2	1.6	-1.2
LDL Cholesterol	0.1	0.1	0.3	0.0	0.3	-0.4	0.1	0.1	0.6	-0.1	-0.4
Lupus	1.5	2.2	4.3	1.5	-1.3	-0.4	1.9	2.1	1.3	1.7	0.8
Neuroticism (2016)	1.3	1.9	4.0	-2.0	0.3	1.4	-1.3	-0.5	-1.3	-2.0	1.4
Primary Biliary Cirrhosis	0.3	0.5	1.1	-0.7	0.3	0.8	-0.5	0.5	-0.4	-1.1	0.9
Rheumatoid Arthritis	0.4	0.5	1.5	0.1	-1.2	0.7	0.2	1.1	0.9	0.0	0.5
Schizophrenia (2014)	2.9	6.5	14.3	2.9	0.1	-3.8	3.2	2.2	2.2	2.9	0.5
Triglycerides	0.9	1.4	6.3	-0.3	0.1	0.7	-0.5	-0.2	0.1	-2.5	2.0
Type 2 Diabetes (T2D) (2012)	2.3	2.7	5.1	1.4	-1.3	0.5	1.0	2.1	2.2	-1.4	2.3
Ulcerative Colitis	0.1	0.2	1.2	0.4	0.4	-1.1	0.2	-0.4	-0.1	0.2	-0.1
Blood Eosinophil Count	0.3	2.7	10.6	1.0	0.3	-0.0	0.7	1.8	1.1	-2.1	3.3
Blood Platelet Count	9.8	114.2	190.4	13.2	-1.4	-5.6	13.0	13.8	12.9	0.8	13.4
Blood Red Count	0.2	2.4	8.0	0.5	1.4	1.4	0.1	2.8	2.5	-0.8	0.5
Blood White Count	0.3	2.2	6.5	-1.0	-1.6	0.9	-0.7	-1.0	-0.3	-2.5	2.2
Heel T-Score	0.3	2.2	5.1	1.2	0.7	-2.2	1.9	-1.7	-0.9	1.8	0.6
BMI	1.0	6.0	17.9	-1.8	-1.3	4.2	-2.1	0.5	-0.2	-3.9	2.4
Height	1.1	22.1	82.7	-4.0	-9.1	6.1	-3.9	1.2	-4.0	-2.7	1.0
Waist Hip Ratio (WHR)	0.3	1.2	3.1	1.0	1.8	0.3	0.8	0.9	1.4	-0.6	1.3
Systolic Blood Pressure	1.0	5.2	13.5	1.1	3.7	-2.6	1.4	-3.4	0.1	-0.9	2.5
Smoking Status	1.4	3.4	7.7	0.7	-0.2	1.6	0.9	1.7	2.6	-2.4	2.8
Allergy or Eczema	0.2	0.4	1.5	0.1	-0.7	0.5	0.0	-0.2	-0.1	1.1	-1.2
Cardiovascular Disease	1.4	4.5	9.6	-2.5	0.9	0.7	-2.1	-3.1	-2.4	-2.7	0.9
Hypothyroidism (self reported)	0.4	1.0	2.7	0.9	-1.3	0.3	0.7	1.7	1.4	0.3	0.0
Respiratory disease	0.5	1.2	5.3	-1.3	0.1	-0.3	-0.8	-1.0	-0.9	0.3	-2.3
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.8	-0.2	-1.7	-0.8	-0.1	-0.4	0.7	0.0	-0.0
Lung FEV1/FVC ratio	1.6	8.1	29.4	3.4	1.4	-0.1	2.7	1.8	2.8	-1.9	5.4
Lung FVC	0.6	3.2	13.4	1.5	-3.7	0.6	1.4	2.3	0.1	1.1	0.8
Neuroticism	0.9	2.1	5.4	-2.1	-0.2	0.1	-1.5	-2.3	-1.9	-0.7	-0.8
Chronotype (morning person)	0.7	1.5	7.2	0.9	0.4	-2.7	1.1	0.1	0.6	1.6	-0.3
Hair Pigment	0.2	4.6	9.4	2.7	-0.5	-2.7	3.1	1.3	2.2	2.2	0.8
Tanning	0.2	2.8	8.1	-1.5	-0.0	2.6	-1.5	-0.7	-0.9	-2.9	1.2
Hand grip strength (left)	0.2	0.6	3.6	0.7	-1.9	0.4	0.4	0.2	-0.3	0.6	0.5
Number of treatments/medications taken	1.0	1.8	4.5	-2.1	-0.7	0.2	-1.5	-1.8	-1.1	-1.8	-0.4
Average weekly spirits intake	1.5	1.9	4.0	-2.0	-0.8	1.5	-1.5	-1.6	-1.5	-0.8	-0.7
Sensitivity / hurt feelings	0.7	1.2	2.7	-1.2	-1.6	1.6	-0.8	-0.9	-0.8	-1.0	-0.0
Frequency of depressed mood in last 2 weeks	3.6	5.0	9.4	-3.0	-1.4	2.5	-2.4	-2.5	-3.1	-1.0	-0.7
Hearing difficulty/problems: Yes	2.5	3.9	6.8	2.5	-0.5	-1.2	2.6	2.3	1.6	2.3	1.7
Relative age of first facial hair	0.6	1.2	5.3	-0.1	0.3	-0.7	-0.1	0.1	-0.6	1.8	-2.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	3.5	-1.3	-1.2	0.5	-1.1	-0.4	-1.9	-1.4	1.3
Ever used hormone-replacement therapy (HRT)	2.2	2.7	6.5	1.7	-0.4	-0.1	2.1	2.5	2.5	0.3	1.2
Ever had hysterectomy (womb removed)	0.5	0.6	2.5	0.1	-0.9	0.4	-0.0	-0.4	-0.1	1.0	-1.6
Systolic blood pressure, automated reading	1.0	2.8	5.7	0.4	2.4	-1.7	0.8	-2.1	0.4	-1.7	2.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.4	-0.9	0.5	0.3	-0.6	-1.2	-0.2	-0.0	-1.1
Angina	2.6	3.4	7.3	2.0	0.8	-0.8	2.2	2.7	2.3	0.9	1.9
Medication for hormone replacement therapy	0.2	0.3	0.8	-0.1	-0.9	0.2	0.2	-0.3	0.0	0.6	-0.8
Vitamin and mineral supplements	2.8	3.8	7.0	2.2	1.3	-1.7	2.3	2.5	2.6	0.1	1.5
Supplements: Zinc	4.8	5.2	10.2	-2.4	-0.9	1.6	-3.2	-2.2	-3.2	0.2	-2.7
Medication: Co-codamol	5.1	5.9	11.9	-2.9	0.4	-0.5	-2.9	-3.4	-3.4	-0.4	-2.5
Medication: Metformin	0.6	0.8	4.1	-0.1	-2.0	0.1	-0.0	0.4	1.5	-0.1	-0.4
Diabetes (father)	0.5	0.6	1.7	0.7	-0.6	0.7	0.6	1.0	1.3	0.6	-0.1
Diabetes (mother)	0.8	1.0	2.5	-0.9	-1.2	1.6	-0.9	-0.6	-1.3	0.3	-0.7
Severe depression (siblings)	0.2	0.2	0.5	0.2	0.7	-0.3	0.3	0.4	-0.4	0.3	0.7
Pack years adult smoking proportion	0.4	0.6	2.8	-0.7	-1.7	0.6	-0.5	-0.1	-0.7	-0.1	-0.2
Impedance of leg (right)	0.2	1.2	4.5	0.2	0.2	-1.2	0.4	-0.3	-0.6	2.1	-1.6
Leg fat-free mass (left)	2.0	10.6	27.8	-2.9	-4.8	5.3	-3.1	0.0	-1.4	-3.7	0.9
Trunk fat percentage	1.0	4.2	11.0	-1.8	-3.0	3.3	-1.4	1.3	-0.0	-2.4	1.0
Hand grip strength (right)	0.2	0.7	2.4	-0.2	-1.5	1.5	-0.2	-0.1	-0.6	-0.4	0.1
Townsend deprivation index at recruitment	0.3	0.4	1.1	0.1	0.8	-0.8	0.2	0.5	1.0	0.4	-0.8
Current tobacco smoking	0.6	0.9	2.3	0.5	1.5	0.7	0.5	1.3	1.3	-0.2	0.8
Average weekly fortified wine intake	0.8	0.9	2.9	0.1	-1.1	1.0	0.4	1.7	0.1	-0.3	1.4
Maternal smoking around birth	1.1	1.6	3.8	-1.2	-1.2	-0.9	-1.1	-1.3	-1.0	1.1	-1.9
Fed-up feelings	1.9	3.5	8.8	-2.4	-0.2	1.3	-2.1	-3.0	-2.2	-1.4	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	3.4	4.6	15.0	-2.3	-0.3	1.6	-2.2	-2.7	-3.9	-0.2	-1.2
Relative age voice broke	0.5	0.8	3.0	-1.0	0.8	0.5	-0.8	-0.7	-0.4	0.4	-1.7
Taking other prescription medications	0.8	1.3	3.1	-1.7	-0.2	0.1	-1.1	-1.6	-1.7	-0.3	-0.7
Age when periods started (menarche)	2.0	4.8	9.0	2.7	2.3	-2.3	2.3	1.5	2.0	3.0	-0.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.3	0.6	-1.5	0.2	0.5	0.5	0.4	1.4	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	4.0	1.9	-1.0	-1.6	2.0	0.9	1.3	1.9	0.4
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	6.5	2.0	-1.0	-2.5	2.5	1.1	1.9	1.2	1.7
Qualifications: CSEs or equivalent	0.4	0.5	1.1	-0.6	0.7	1.0	-0.6	-0.7	-0.5	-1.1	0.2
Serious illness, injury or assault to yourself	0.4	0.5	1.6	0.7	1.2	-0.6	0.5	0.5	0.1	0.3	0.9
High blood pressure	1.8	5.2	13.0	-2.5	1.1	0.0	-2.0	-3.6	-3.0	-2.6	0.7
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.0	0.5	-0.7	0.0	0.4	-0.1	0.4	1.4	-1.0
Multivitamins +/- minerals	4.4	5.6	8.8	-2.7	-2.4	2.7	-2.7	-2.6	-3.0	-0.3	-1.5
Stomach or abdominal pain in last month	1.2	1.5	7.1	1.2	0.7	-1.3	1.1	0.2	-0.4	2.7	-0.0
Supplements: Glucosamine	2.5	3.2	6.2	-2.5	-0.7	1.8	-2.2	-1.6	-1.0	-2.5	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.4	0.6	0.4	-1.6	0.8	0.1	-0.7	1.3	-0.4
Medication: Atenolol	2.0	2.4	7.1	-1.2	-0.6	1.1	-1.6	-2.7	-2.5	-0.5	-0.1
Medication: Levothyroxine sodium	0.5	0.8	1.9	1.4	-0.6	0.4	1.0	1.1	0.9	1.1	-0.3
Sitting height	1.7	12.3	51.7	-2.5	-7.2	3.4	-2.5	-1.9	-4.1	-0.6	-1.2
Chronic bronchitis/emphysema (father)	1.0	1.2	3.4	0.3	-0.8	-1.8	0.3	-1.5	-1.3	1.1	-0.7
High blood pressure (mother)	0.7	1.0	1.8	-0.9	1.3	0.3	-0.7	-1.3	-0.9	-1.3	0.6
Body mass index (BMI)	0.7	3.1	9.6	-1.3	-1.3	3.1	-1.2	0.8	0.7	-2.8	1.1
Impedance of leg (left)	0.2	1.1	3.2	0.6	0.5	-1.7	0.8	-0.2	-0.1	1.8	-1.2
Leg predicted mass (left)	2.0	10.6	28.0	-2.9	-4.8	5.3	-3.1	0.0	-1.3	-3.6	0.8
Trunk fat mass	1.7	7.4	20.0	-2.5	-3.9	4.5	-2.2	1.1	-0.6	-3.2	1.0
Waist circumference	1.3	4.8	15.6	-1.9	-2.1	3.9	-1.8	1.1	0.1	-3.0	1.0
Number of incorrect matches in round	0.8	1.3	6.0	0.1	-0.9	0.4	0.5	-0.9	-1.1	2.4	-0.9
Past tobacco smoking	0.8	1.5	3.7	0.2	1.0	-0.9	-0.4	-1.1	-1.2	1.9	-1.9
Alcohol usually taken with meals	0.5	0.8	2.8	-1.0	-0.6	1.0	-1.1	0.2	-0.3	-1.7	-0.0
Nervous feelings	0.2	0.3	2.2	0.2	0.4	0.1	0.1	-0.3	-0.2	1.5	-0.4
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	4.5	-1.5	-0.6	1.3	-1.2	-1.1	-2.1	0.1	-0.8
Hearing difficulty/problems with background noise	1.0	1.6	3.3	1.2	-0.6	-0.2	1.3	1.8	1.8	0.4	1.7
Hair/balding pattern: Pattern 2	0.2	0.2	0.9	-0.5	-0.4	0.9	-0.6	-0.0	-0.2	-0.3	-0.3
Had menopause	0.7	0.9	2.0	-1.3	-1.4	1.1	-0.8	0.1	-0.6	-1.1	-0.0
Had other major operations	1.0	1.2	3.8	-1.4	-0.7	0.6	-1.1	-1.0	-1.9	-0.6	0.1
Forced vital capacity (FVC)	2.3	9.1	49.9	-1.1	-7.1	3.8	-1.4	1.0	-1.7	-0.0	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.1	1.1	-0.3	-1.4	1.2	0.6	1.1	0.7	0.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.7	1.1	-0.7	-0.1	1.3	0.2	0.6	0.7	0.8
Qualifications: None of the above	0.1	0.2	0.4	-0.4	0.6	-0.4	-0.1	-0.4	-0.6	0.3	-0.5
Financial difficulties in last 2 years	0.6	0.7	2.6	-0.7	1.2	0.2	-0.6	-0.6	-0.4	-1.6	0.7
Mouth/teeth dental problems	0.1	0.2	0.3	0.4	-0.5	-0.0	0.4	-0.3	0.5	0.5	-0.3
Heart attack	0.6	0.8	2.5	1.2	-1.6	0.0	0.8	0.6	0.5	0.3	0.9
Allergy	0.5	1.2	4.3	-0.4	0.4	0.6	-0.7	-0.1	-0.5	-1.9	2.1
Pain all over the body in last month	1.5	1.6	3.9	1.4	0.8	-0.7	1.4	1.2	2.0	-0.7	1.6
Diabetes (self-reported)	0.3	0.5	1.4	-0.1	-0.6	-1.2	0.2	0.1	1.0	0.3	-0.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.2	0.1	0.4	0.4	-0.2	-0.4	0.2	0.4	-1.1
Medication: Ramipril	0.3	0.4	1.6	0.6	-0.2	-0.7	0.5	0.4	0.3	0.2	1.3
Medication: Simvastatin	0.3	0.4	1.3	-0.2	0.3	-0.8	0.1	-0.1	0.4	-1.0	1.1
Fluid intelligence score	0.4	0.9	1.9	-1.0	-0.5	-0.2	-0.7	-0.8	-0.8	1.3	-1.4
Illnesses of siblings	1.0	1.4	3.4	1.1	1.6	-0.3	0.3	1.8	1.8	0.7	-0.2
Neuroticism score	0.4	0.9	3.1	-1.2	-0.4	-0.3	-0.7	-1.7	-1.1	0.3	-0.7
Weight	2.2	10.9	30.1	-3.1	-4.7	5.5	-3.1	0.4	-1.1	-3.8	0.7
Impedance of arm (right)	0.5	2.1	10.0	0.7	-1.1	-1.5	1.0	0.7	-0.3	3.2	-1.2
Arm fat percentage (right)	0.6	2.5	8.5	-1.1	-1.6	2.9	-0.7	1.5	0.7	-1.8	1.1
Trunk fat-free mass	2.3	13.5	32.8	-3.3	-5.3	5.7	-3.7	-0.5	-1.8	-4.3	0.7
Hip circumference	1.6	7.1	17.8	-2.5	-4.0	4.2	-2.4	0.7	-0.9	-3.0	0.7
Time employed in main current job	2.3	2.7	4.1	1.9	-0.4	-1.9	2.0	2.0	1.3	1.5	1.5
Alcohol intake versus 10 years previously	1.0	1.5	6.6	1.0	0.1	-0.8	1.3	0.3	0.3	2.6	-1.2
Father’s age at death	1.2	1.6	3.2	-1.8	-0.6	1.3	-1.3	-1.2	-1.7	0.0	-1.2
Worrier / anxious feelings	1.3	2.5	10.8	0.8	-0.6	-2.1	0.8	-0.3	-0.6	3.3	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	6.1	-1.9	-0.4	1.0	-1.0	-1.8	-2.5	0.6	-1.3
Falls in the last year	0.3	0.4	1.4	0.1	-0.3	0.0	0.2	-0.9	-0.6	-0.9	1.2
Hair/balding pattern: Pattern 3	0.5	0.7	1.8	0.7	-1.2	-1.0	0.9	-0.1	0.1	1.3	0.3
Number of live births	0.9	1.3	3.1	1.4	-0.3	-0.6	1.4	1.5	0.5	1.8	0.4
Forced expiratory volume in 1-second (FEV1)	1.7	5.9	32.2	-0.3	-5.7	3.4	-0.7	1.3	-0.8	-0.4	0.5
Pulse rate	1.0	1.7	7.5	-0.8	0.3	2.7	-0.8	0.9	0.2	0.8	-1.8
Happiness	0.2	0.3	1.4	-0.1	-0.3	0.3	-0.4	-0.4	-0.3	-1.2	0.6
Noisy workplace	0.3	0.4	1.0	-0.1	-0.5	0.7	0.3	0.8	0.4	0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.2	0.9	0.2	-0.9	0.8	0.8	0.1	1.1	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.7	-0.3	-1.3	1.3	-0.0	0.3	0.1	1.3	-1.3
Mouth/teeth dental problems: Dentures	1.3	2.3	4.5	-1.4	-2.1	1.9	-1.6	-0.1	-0.8	-2.1	0.5
Asthma	0.5	1.1	3.6	-0.9	1.7	-0.7	-0.4	-0.8	-0.2	-0.3	-1.9
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.8	-0.0	-0.9	0.4	0.1	0.1	0.8	-0.8	0.1
Medication: Cholesterol lowering	0.2	0.3	1.0	0.1	-0.3	-1.0	0.0	-0.5	-0.8	0.6	0.7
Depression (self-reported)	0.2	0.2	0.5	0.0	-0.6	0.4	0.5	-0.0	0.4	-0.7	0.4
Medication: Lansoprazole	0.3	0.4	1.4	1.2	-0.4	-0.5	0.7	0.4	-0.4	0.4	0.7
Prospective memory result	0.4	0.4	1.2	0.6	0.7	0.2	0.1	0.5	1.1	-0.7	0.8
Lung cancer (father)	3.0	3.5	9.8	-1.8	0.1	-0.2	-1.7	-2.3	-3.1	0.7	-2.5
Illnesses of mother	1.4	1.7	3.1	1.8	-0.4	-1.7	1.3	1.1	1.6	1.5	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	30.1	-0.0	-5.5	2.9	-0.4	1.0	-0.5	-0.1	0.6
Pulse wave Arterial Stiffness index	0.6	0.7	2.3	0.1	0.2	-0.0	0.3	1.5	1.3	-0.4	1.1
Impedance of arm (left)	0.5	2.3	10.0	0.1	-1.2	-1.2	0.5	0.3	-0.9	3.2	-2.1
Arm fat mass (right)	1.5	6.0	17.8	-1.9	-3.3	4.2	-1.7	1.3	0.4	-3.1	1.1
Trunk predicted mass	2.4	13.5	32.9	-3.4	-5.2	5.7	-3.7	-0.5	-1.8	-4.3	0.7
Standing height	1.8	18.1	59.7	-3.8	-7.7	5.6	-4.1	-0.5	-3.6	-3.0	-0.4
Length of working week for main job	0.5	0.5	1.5	0.7	0.2	-0.6	0.7	0.8	0.1	1.2	0.9
Exposure to tobacco smoke at home	0.5	0.6	1.6	0.1	-1.2	-0.9	0.2	0.5	-0.5	1.1	-0.6
Breastfed as a baby	0.5	0.6	2.1	-0.6	0.7	0.8	-0.6	0.4	0.7	-1.5	0.7
Tense / ‘highly strung’	0.8	1.3	2.7	-1.0	0.5	0.8	-1.3	-1.2	-1.6	-1.6	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.0	-1.0	-1.7	1.2	-0.5	-0.6	-1.0	1.2	-1.7
Hair/balding pattern: Pattern 4	1.3	3.2	8.7	-2.0	0.3	0.8	-2.2	-2.9	-2.0	-1.0	-1.6
Birth weight of first child	0.2	0.4	1.7	0.0	-0.7	0.4	0.2	1.3	-0.3	1.0	-0.4
Peak expiratory flow (PEF)	1.1	2.6	5.2	2.0	-1.6	0.2	1.8	2.3	0.8	1.1	2.0
Pulse wave reflection index	1.5	1.9	5.7	1.0	1.5	-1.4	1.0	1.0	1.1	-1.1	2.4
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.6	0.5	-1.5	-0.5	0.9	0.3	2.1	-1.0	0.7
Loud music exposure frequency	0.6	0.6	2.6	0.5	-0.4	-0.4	1.2	0.4	0.1	-0.2	1.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.2	-0.7	0.7	-0.2	-0.2	-0.5	-0.2	-1.6	1.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.5	1.0	0.2	-1.1	1.1	1.2	0.3	1.1	0.1
Blood clot in the leg (DVT)	2.8	3.7	11.3	-2.4	-1.1	0.3	-1.9	-1.6	-1.9	1.0	-3.4
Medication: Paracetamol	1.0	1.7	4.4	-1.7	0.8	-0.7	-1.4	-2.1	-0.4	-1.0	-1.4
Headache pain in last month	2.9	5.0	11.0	-2.7	-1.4	1.2	-2.3	-2.2	-2.7	0.8	-3.3
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.9	1.6	0.2	0.3	1.6	1.5	1.7	1.0	-0.1
Glaucoma (self-reported)	3.2	3.7	9.9	-2.6	0.8	2.0	-2.7	-1.1	-0.8	-3.1	-0.1
Gout (self-reported)	1.0	1.3	3.7	-1.5	-0.7	0.9	-1.9	-0.4	-1.2	-0.5	-1.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.6	-0.1	-0.7	0.8	-0.2	0.4	0.4	0.1	-0.7
Medication: Amlodipine	0.4	0.5	1.9	-0.6	-0.5	0.0	-0.5	-1.4	-0.8	0.2	-0.7
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.6	-1.2	-0.8	-0.5	-0.7	-1.4	-1.6	0.3	-1.5
Birth weight	0.5	1.1	3.4	0.5	-1.4	0.6	0.2	1.8	-0.0	1.2	-1.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	-0.8	-0.1	0.9	-0.1	-0.1	-0.2	-0.6	0.2
High blood pressure (siblings)	1.0	1.4	4.6	-0.8	-1.5	-0.8	-0.2	-1.6	-2.1	-0.6	0.6
Forced vital capacity (FVC), Best measure	2.1	7.5	42.2	-1.1	-6.5	3.4	-1.2	0.6	-1.7	0.2	-0.8
Body fat percentage	0.9	3.6	11.7	-1.8	-2.1	3.4	-1.4	1.1	0.1	-2.4	0.7
Leg fat percentage (right)	0.8	2.9	10.2	-2.0	-0.9	3.2	-1.8	0.2	-0.3	-2.2	-0.1
Arm fat-free mass (right)	2.2	11.3	28.5	-3.0	-4.7	5.3	-3.2	0.0	-1.2	-4.3	0.9
Exposure to tobacco smoke outside home	0.7	1.0	3.5	-1.4	-1.9	-0.3	-0.9	-0.2	-0.6	-0.3	-0.9
Comparative body size at age 10	0.9	2.4	5.3	-1.9	-1.7	2.3	-1.9	0.3	-0.3	-1.9	-0.3
Number of full brothers	0.8	1.0	4.8	-0.2	0.4	0.6	-0.1	-0.4	0.2	1.6	-2.2
Worry too long after embarrassment	0.2	0.4	1.2	-1.1	0.2	0.4	-0.5	-0.9	-0.0	-0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.8	-0.8	-0.8	0.3	-0.5	-0.1	-0.3	0.5	-0.9
Wheeze or whistling in the chest in last year	0.8	1.4	6.9	-1.0	2.6	0.6	-0.8	-0.8	-0.7	-1.0	-0.4
Number of children fathered	0.2	0.2	0.7	0.0	-0.1	-0.8	-0.3	0.4	-0.0	-0.8	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.4	1.0	0.1	-1.6	0.7	1.1	0.2	1.2	-0.7
Age at first live birth	0.6	1.1	2.6	-1.3	0.3	-0.1	-1.6	-1.0	-0.9	-1.5	-0.4
Pulse wave peak to peak time	0.6	0.6	1.8	-0.2	-0.7	0.2	-0.3	-1.4	-1.3	0.2	-0.9
Health satisfaction	0.9	1.2	1.9	-1.4	1.3	0.3	-1.0	-1.4	-1.2	-1.0	-0.9
Shortness of breath walking on level ground	3.3	3.9	8.6	-2.9	-0.4	2.5	-2.6	-1.5	-1.6	-1.9	-1.0
Qualifications: College or University degree	0.4	1.2	3.7	0.6	-1.9	0.1	-0.4	0.3	-0.5	1.7	-1.6
Eye problems/disorders: None of the above	1.3	1.5	4.4	-1.0	-0.3	0.3	-1.0	-0.9	-1.5	-2.1	1.4
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.9	-1.0	-0.2	0.3	-1.0	-1.4	-1.3	-0.9	0.4
Emphysema/chronic bronchitis	1.0	1.1	3.3	-1.0	-1.6	0.4	-0.7	-0.9	-1.0	0.4	-1.8
Medication for pain relief, constipation, heartburn	0.3	0.4	1.3	0.9	0.7	-0.2	0.5	0.5	-0.5	1.1	0.1
Neck or shoulder pain in last month	1.1	1.6	3.8	-1.7	0.7	0.7	-1.3	-1.7	-1.9	-0.4	-0.5
Medication: Blood pressure	2.0	3.6	7.4	-2.6	0.7	0.1	-2.6	-2.7	-2.4	-1.3	-0.4
Angina (self-reported)	2.0	2.6	5.9	1.8	0.9	-0.8	2.0	2.4	1.9	0.8	1.6
Migraine (self-reported)	0.8	1.0	2.4	-0.9	-1.1	1.6	-0.7	-0.3	-0.7	0.2	-1.5
Medication: Ibuprofen	0.3	0.3	1.1	0.3	-0.5	-0.1	0.3	0.4	1.0	-0.9	0.4
Medication: Allopurinol	0.8	1.1	2.7	-1.2	-0.8	0.7	-1.6	-0.5	-1.1	-0.1	-1.5
Medication: Omeprazole	0.4	0.5	0.9	-1.0	-0.3	0.5	-1.0	-0.3	-0.6	-0.9	-0.4
Medication: Seretide 50 evohaler	1.6	1.8	4.3	-1.9	-0.9	0.5	-1.5	-1.2	-0.9	-2.1	-1.0
Mean time to correctly identify matches	0.5	0.9	4.1	-0.2	0.0	-0.5	-0.1	-0.1	-0.1	-1.7	2.0
Heart disease (mother)	0.5	0.6	2.0	-0.5	-1.4	-0.3	-0.4	-0.2	-1.4	0.8	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	4.8	-1.0	2.2	0.7	-1.1	-0.7	0.0	-0.5	0.2
Whole body fat mass	1.6	6.8	19.9	-2.5	-3.3	4.5	-2.2	0.9	-0.5	-3.3	0.8
Leg fat mass (right)	1.3	4.9	16.0	-2.2	-2.1	4.0	-2.0	0.9	-0.1	-3.0	0.6
Arm predicted mass (right)	2.2	11.4	28.6	-3.2	-4.4	5.3	-3.5	-0.3	-1.5	-4.3	0.6
Pulse rate, automated reading	0.5	1.7	7.5	-1.0	-0.9	2.7	-1.0	0.7	0.4	-0.3	-1.6
Alcohol intake frequency.	1.0	2.3	9.8	-0.9	-0.2	-0.5	-1.0	-3.1	-1.7	0.9	-1.6
Comparative height size at age 10	2.4	13.0	39.6	-3.5	-6.3	4.7	-3.5	-0.7	-3.2	-2.8	0.2
Number of full sisters	1.5	1.8	3.2	-1.8	-0.3	0.6	-1.8	-1.6	-1.2	-1.0	-1.6
Suffer from ‘nerves’	0.1	0.2	1.1	-0.1	1.0	0.3	-0.3	-0.4	-0.2	-0.1	0.3
Overall health rating	0.7	1.6	3.9	-1.8	0.3	0.4	-0.9	-1.6	-2.0	-1.3	0.2
Chest pain or discomfort	0.1	0.2	0.6	-0.2	0.5	0.4	-0.0	-0.5	-0.5	0.1	0.8
Had major operations	0.6	0.7	2.1	0.6	-0.8	-0.7	1.1	0.8	0.1	1.4	0.5
Age at last live birth	0.6	0.9	1.7	-1.1	1.3	-1.0	-1.1	-0.5	-0.7	-1.2	-0.1
Family relationship satisfaction	1.5	1.8	2.9	-1.2	-1.4	1.6	-1.6	-0.9	-1.3	-1.7	0.8
Leg pain on walking	0.8	1.0	2.5	-1.6	-0.0	1.4	-1.1	1.0	-0.7	-0.8	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.4	0.6	-0.4	-0.6	1.2	0.6	0.3	0.9	0.1
Commuting to job workplace: Car/motor vehicle	1.3	1.5	6.0	-1.1	-0.7	2.4	-1.7	0.0	-1.0	-0.4	-0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.8	0.2	0.2	-0.4	-0.3	-0.5	-0.2	0.4	-0.9
Medication: Aspirin	2.0	2.7	6.8	0.5	-1.4	2.2	0.5	1.8	1.6	-1.4	2.6
Supplements: Vitamin C	0.6	0.8	3.0	-0.4	-0.1	-0.1	-0.5	-1.1	-0.7	1.0	-1.7
Knee pain experienced in last month	0.8	1.3	4.8	-1.4	0.3	2.2	-1.0	-0.1	-0.3	-1.4	0.3
Hypertension (Self-reported)	1.7	4.8	10.8	-2.5	1.5	0.0	-2.0	-3.3	-2.9	-2.5	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.1	0.9	-0.8	-0.3	0.7	-0.3	-0.8	1.1	0.3
Illnesses of father: Heart disease	0.8	1.0	3.3	1.2	0.0	-0.8	1.0	0.6	1.0	-0.7	1.8
Illnesses of siblings: Diabetes	1.6	1.9	3.4	-1.6	-1.6	0.7	-1.2	-1.8	-1.6	0.3	-1.6
Smoking status: Previous	0.9	1.4	4.1	-0.2	-0.6	1.3	0.1	0.7	0.6	-2.0	1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	5.6	-1.8	-2.4	1.6	-1.8	-1.0	-0.7	-0.9	-0.8
Whole body fat-free mass	2.2	12.7	32.0	-3.1	-5.2	5.7	-3.4	-0.2	-1.5	-4.3	1.0
Leg fat-free mass (right)	1.7	9.3	23.5	-2.6	-4.6	4.8	-2.8	-0.0	-1.1	-3.6	1.0
Arm fat percentage (left)	0.7	2.7	9.7	-1.6	-1.8	3.1	-1.2	1.1	0.3	-1.9	0.4
Average weekly red wine intake	1.1	1.6	4.6	-1.0	-0.4	1.6	-1.5	0.6	-0.9	-2.1	0.9
Handedness (chirality/laterality): Left-handed	1.2	1.4	6.7	0.4	-2.6	-1.3	0.2	0.1	-0.9	1.3	0.1
Mood swings	0.3	0.5	1.4	-0.8	-1.2	-0.8	-0.1	-1.0	-0.6	0.4	-0.3
Loneliness, isolation	2.4	3.3	6.6	-2.1	0.2	2.6	-2.0	-1.9	-2.2	-1.7	-0.4
Long-standing illness, disability or infirmity	2.2	3.3	6.4	-2.5	-1.1	1.8	-2.2	-2.0	-2.0	-0.9	-1.5
Ever had bowel cancer screening	0.8	0.9	2.2	-1.5	-0.9	1.3	-0.9	0.0	-1.0	-0.8	0.1
Diabetes diagnosed by doctor	0.1	0.2	0.8	-0.3	-0.4	-0.5	-0.1	0.3	0.9	-0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	6.1	-0.2	2.5	0.2	-0.3	-0.9	-1.9	-0.8	0.7
Friendships satisfaction	1.7	2.1	8.6	-1.4	0.5	-0.1	-1.6	-1.6	-2.9	0.4	-0.7
Qualifications: nursing, teaching	0.2	0.3	1.0	0.2	-0.2	0.1	0.1	0.5	0.5	-0.8	1.0
Commuting to job workplace: Walk	1.0	1.0	2.1	1.0	0.9	-1.3	1.3	0.5	1.4	0.5	0.8
Eye problems/disorders: Cataract	2.8	3.2	11.7	1.5	-0.7	-1.8	1.6	0.8	1.2	3.4	-1.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.9	-0.4	1.4	-0.3	-0.5	-0.7	-0.1	0.5	-1.2
Medication for cholesterol	1.9	2.9	9.6	-1.3	0.5	0.9	-2.1	-2.0	-1.6	0.5	-3.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.3	-1.2	-0.7	-0.1	-0.7	-1.5	-0.7	-0.4	-0.7
Back pain experienced in last month	1.1	1.6	3.8	-1.7	-0.1	0.2	-1.5	-1.9	-1.0	-0.9	-1.4
Mineral and other dietary supplements	1.7	2.3	6.4	1.3	-0.3	-0.3	1.6	2.2	1.6	-0.5	2.5
Breast cancer (self-reported)	0.3	0.4	1.0	-0.5	-0.9	-0.4	-0.6	-1.0	-0.5	-0.7	0.3
Asthma (self-reported)	0.4	0.9	2.7	-0.6	1.6	-0.8	-0.2	-0.6	0.1	-0.1	-1.6
Osteoporosis (self-reported)	0.4	0.5	2.1	0.3	0.9	-1.4	0.2	-0.2	-0.7	0.6	-0.2
Osteoarthritis (self-reported)	0.4	0.6	3.0	-0.8	0.1	0.5	-0.7	0.1	-0.3	-1.7	0.3
Medication: Aspirin	2.1	2.7	4.8	0.6	-2.0	1.9	0.5	2.0	1.9	-0.9	2.2
Medication: Gliclazide	1.9	2.1	7.3	1.1	-0.8	1.9	0.4	2.7	1.6	0.0	1.0
Illnesses of father: None of the above (group 1)	0.2	0.2	1.1	-0.1	-0.2	0.8	0.1	1.0	0.3	0.4	0.1
Smoking status: Current	0.3	0.5	1.4	0.3	1.0	0.5	0.4	1.0	1.2	-0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	9.8	1.3	-3.1	0.9	0.8	0.7	-0.1	0.8	0.9
Whole body water mass	2.2	12.4	30.6	-3.1	-5.0	5.5	-3.4	-0.2	-1.4	-4.3	1.1
Leg predicted mass (right)	1.8	9.5	24.0	-2.6	-4.5	4.9	-2.9	-0.1	-1.1	-3.7	1.0
Arm fat mass (left)	1.4	5.6	17.9	-2.2	-3.1	4.2	-2.0	1.0	-0.2	-2.8	0.7
Number of self-reported non-cancer illnesses	0.5	0.9	2.5	-1.6	0.8	-0.2	-0.7	-0.9	-1.1	-1.3	-0.4
Average weekly champagne plus white wine intake	1.2	1.6	5.1	-1.2	-1.5	0.9	-1.3	-0.5	-1.1	-2.3	-0.0
Miserableness	0.2	0.4	2.0	-0.7	-0.2	0.3	0.2	-0.0	-0.1	-0.8	1.4
Guilty feelings	0.5	0.8	2.5	-0.7	-0.2	-0.5	-0.5	-1.6	-1.1	0.7	-1.0
Wears glasses or contact lenses	1.5	1.7	6.0	-1.6	-0.4	2.5	-1.4	-0.9	-1.2	-0.6	-0.6
Ever taken oral contraceptive pill	1.7	1.9	3.2	1.5	1.4	-0.6	1.6	1.2	1.8	1.7	0.7
Hearing aid user	0.8	0.9	2.4	-1.4	-0.4	1.1	-0.7	-0.5	-1.6	0.4	-0.7
Mother’s age at death	1.4	1.7	4.0	1.6	1.4	-1.5	1.4	1.0	0.0	2.0	-0.2
Financial situation satisfaction	0.6	0.7	5.7	-0.0	2.4	-0.2	-0.2	-0.3	0.3	0.0	-0.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.8	1.1	0.3	-0.6	1.3	0.1	1.3	0.7	0.3
Commuting to job workplace: Public transport	1.5	1.8	4.4	1.2	1.4	-1.7	1.6	0.5	2.1	0.6	0.4
Eye problems/disorders: Glaucoma	2.9	3.5	7.1	-2.5	1.2	1.4	-2.5	-1.8	-0.7	-2.7	-0.7
Medication: Blood pressure	0.7	1.4	5.3	0.8	-1.2	-1.1	1.4	0.6	0.3	-0.3	2.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.9	0.6	-0.0	-0.5	0.9	0.9	0.1	0.2	0.9
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.7	-1.2	0.7	0.8	-1.5	-1.9	-1.4	-0.3	-1.5
High cholesterol (Self-reported)	0.0	0.1	0.2	-0.3	-0.3	-0.2	-0.1	-0.5	0.2	-0.3	-0.1
Medication: Bendroflumethiazide	1.1	1.7	4.2	-1.5	0.5	1.1	-1.2	-2.1	-1.6	-1.2	0.1
Medication: Paracetamol	1.3	2.1	6.0	-1.8	0.9	-0.8	-1.4	-2.5	-0.3	-1.2	-1.6
Medication: Lisinopril	0.2	0.3	1.0	-0.4	-0.7	0.4	-0.3	-0.3	-0.4	-1.0	0.5
Medication: Atorvastatin	2.6	3.2	7.6	2.8	0.5	-1.2	2.4	1.6	0.9	1.9	1.9
Illnesses of father: High blood pressure	0.2	0.3	1.4	-0.2	0.4	0.3	-0.1	-1.2	0.1	-0.4	-0.8
Alcohol drinker status: Never	0.8	1.0	2.6	-0.7	0.4	-0.4	-1.4	-1.5	-0.3	-0.4	-1.6
Ever smoked	1.6	2.8	6.2	0.4	-0.8	0.3	1.0	2.1	2.3	-2.0	2.5
Basal metabolic rate	2.3	12.8	32.1	-3.2	-5.2	5.7	-3.4	-0.1	-1.4	-4.2	0.9
Leg fat percentage (left)	0.7	2.6	8.6	-1.8	-0.7	2.9	-1.5	0.4	0.1	-2.5	0.3
Arm fat-free mass (left)	2.4	12.0	29.8	-3.1	-4.4	5.5	-3.4	-0.2	-1.2	-4.7	1.3
Number of operations (self-reported)	0.7	1.1	2.6	0.5	-1.5	-0.3	1.1	1.5	0.3	0.4	1.6
Average weekly beer plus cider intake	1.1	1.6	4.9	1.3	0.4	-0.2	1.5	1.3	1.5	2.2	0.1
Irritability	0.2	0.3	1.1	-0.1	0.1	-0.6	-0.0	-0.0	0.5	-1.0	1.1
Risk taking	0.9	1.4	5.6	0.4	0.0	0.3	0.4	1.2	0.6	-1.8	2.4
Ever had prostate specific antigen (PSA) test	2.3	2.6	6.3	-2.2	-0.2	0.5	-2.5	-1.7	-1.3	-1.6	-1.4
Fractured/broken bones in last 5 years	0.6	0.8	3.3	0.4	1.8	-0.2	0.7	0.4	1.2	-0.1	0.8
Age started oral contraceptive pill	0.5	0.6	2.2	0.3	-0.9	-0.7	0.6	0.6	1.5	-0.6	0.2
Diastolic blood pressure, automated reading	1.3	3.9	9.9	1.7	1.6	-0.9	1.8	1.4	2.7	-1.5	3.2
Ever depressed for a whole week	1.5	1.9	4.2	1.9	0.2	-0.4	2.0	1.3	1.8	1.5	0.3
Unable to work because of sickness or disability	0.9	1.1	2.8	-1.3	0.6	1.0	-1.1	-1.7	-1.3	-0.2	-0.5
Commuting to job workplace: Cycle	1.5	1.9	6.3	-1.1	-0.9	-0.6	-1.3	-1.6	-1.3	0.5	-2.5
Myopia	1.5	2.2	4.7	-1.7	-1.1	1.3	-1.5	-1.8	-2.2	-0.5	-1.1
Vascular/heart problems diagnosed by doctor	1.1	3.1	6.5	1.7	-0.9	0.5	1.1	2.5	2.2	2.5	-1.5
Cholesterol lowering medication	1.3	1.8	4.6	1.5	0.4	-0.7	1.8	2.1	1.6	0.6	1.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.0	-0.6	0.2	0.5	-0.7	-0.1	-0.3	-1.0	-0.2
Pain experienced in last month	1.5	2.4	4.1	2.0	-0.3	-1.7	2.0	1.7	1.3	1.4	1.3
Supplements: Calcium	2.5	2.8	5.6	-2.0	-0.0	1.0	-2.4	-2.1	-2.0	-1.5	-0.9
Basal cell carcinoma (self-reported)	0.4	0.4	1.1	-0.5	-0.7	-1.1	-0.6	-0.7	-0.8	-0.1	0.1
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.6	1.3	-1.6	-0.0	0.8	0.5	0.5	0.6	0.7
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	10.2	-2.4	-1.3	0.5	-1.9	-1.7	-1.9	0.9	-3.2
Heart disease (siblings)	0.3	0.4	1.4	0.4	-1.2	0.1	0.7	0.1	-0.4	0.6	-0.4
Alcohol drinker status: Previous	0.8	0.9	4.2	-0.6	0.7	-0.3	-0.7	-2.0	-1.3	-0.2	-0.1
Pack years of smoking	0.3	0.5	3.1	-0.5	-1.8	0.3	-0.3	0.2	-0.5	-0.2	-0.0
Impedance of whole body	0.4	2.1	9.3	0.7	-0.3	-1.6	1.0	0.3	-0.4	3.1	-1.7
Leg fat mass (left)	1.3	5.1	16.0	-2.2	-2.2	4.0	-2.0	0.8	-0.1	-3.2	0.8
Arm predicted mass (left)	2.1	10.9	28.4	-2.8	-4.6	5.3	-3.1	0.1	-1.0	-4.2	1.2