[Hub]/) : Traits : Whole body water mass : ← →

chr7:1,787,236-3,581,391

Best TWAS P=5.91e-39 · Best GWAS P=6.73e-38 conditioned to 0.439

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	6.2	7.8	6.7e-15	-0.44	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-8.0	-8.9	5.2e-19	0.73	0.23	0.77	FALSE
3	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-12.9	-11.1	1.7e-28	0.87	0.02	0.98	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-12.8	-12.8	2.2e-37	0.92	0.01	0.99	FALSE
5	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-12.9	-10.5	5.8e-26	0.89	0.02	0.98	FALSE
6	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-7.9	-10.7	1.3e-26	0.84	0.03	0.90	FALSE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	6.5	-7.5	5.2e-14	0.64	0.24	0.74	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-8.0	-10.8	4.7e-27	0.85	0.05	0.94	FALSE
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-12.7	-11.7	9.4e-32	0.89	0.01	0.99	FALSE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-12.9	-12.4	1.6e-35	0.98	0.00	1.00	FALSE
11	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-12.7	-10.4	2.0e-25	0.77	0.01	0.99	FALSE
12	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-8.1	-10.5	6.5e-26	0.85	0.84	0.16	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	6.2	-6.9	5.2e-12	0.53	0.34	0.64	FALSE
14	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-7.9	-10.5	1.3e-25	0.88	0.13	0.87	FALSE
15	GTEx	Skin Sun Exposed Lower leg	AC004840.9	0.18	0.01	enet	36	0.02	3.7e-03	2.7	-5.3	1.1e-07	0.13	0.18	0.20	TRUE
16	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-8.1	-8.8	1.7e-18	0.73	0.07	0.77	FALSE
17	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-7.9	-8.1	7.7e-16	0.68	0.45	0.54	FALSE
18	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-12.5	-12.5	5.3e-36	0.95	0.02	0.91	FALSE
19	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-8.1	-8.2	2.6e-16	0.74	0.29	0.71	FALSE
20	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-9.4	-9.1	7.7e-20	0.63	0.92	0.08	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-12.9	13.1	5.9e-39	-0.95	0.01	0.99	TRUE
22	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	5.9	-8.1	4.6e-16	0.51	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	7.9	-11.0	3.2e-28	0.74	0.01	0.69	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-8.0	-8.1	8.5e-16	0.70	0.07	0.78	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	7.9	9.2	3.5e-20	-0.64	0.03	0.92	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	5.2	-10.3	6.8e-25	0.78	0.06	0.73	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	-8.0	5.7	1.3e-08	-0.64	0.04	0.80	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	-9.4	5.7	1.6e-08	-0.56	0.16	0.84	FALSE