[Hub]/) : Traits : Whole body water mass : ← →

chr6:151,030,107-154,145,492

Best TWAS P=6.97e-09 · Best GWAS P=2.4e-25 conditioned to 4.51e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa RMND1 0.34 0.09 lasso 6 0.19 4.8e-13 4.7 -5.3 1.2e-07 -0.01 1.00 0.00 FALSE
2 ROSMAP Brain Pre-frontal Cortex SYNE1 0.12 0.01 blup 875 0.05 6.9e-07 1.0 5.4 6.4e-08 0.26 0.63 0.08 TRUE
3 YFS Blood RGS17 0.10 0.11 enet 11 0.11 6.3e-33 5.3 5.2 2.5e-07 -0.01 0.01 0.99 FALSE
4 YFS Blood RMND1 0.06 0.06 lasso 12 0.05 6.5e-16 4.9 -5.5 4.9e-08 -0.01 1.00 0.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma RGS17 0.02 0.02 enet 5 0.02 1.8e-04 5.3 -5.3 1.4e-07 0.02 0.01 0.98 TRUE
6 The Cancer Genome Atlas Breast Invasive Carcinoma RMND1 0.02 0.00 blup 57 0.01 3.1e-03 4.6 -5.5 3.5e-08 -0.02 0.00 0.61 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RMND1 0.16 0.10 lasso 7 0.12 1.6e-06 4.9 -5.8 7.5e-09 -0.02 0.02 0.98 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma RMND1 0.12 0.09 enet 9 0.10 4.2e-04 4.1 -5.2 2.2e-07 -0.03 0.08 0.28 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RMND1 0.07 0.06 blup 58 0.09 1.4e-10 4.9 -5.7 1.1e-08 0.01 0.18 0.82 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RMND1 0.09 0.10 lasso 4 0.10 1.6e-11 4.7 -5.3 1.2e-07 0.03 0.51 0.49 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma RMND1 0.05 0.06 lasso 2 0.07 4.3e-08 6.1 -5.8 7.0e-09 -0.04 0.00 1.00 TRUE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma RMND1 0.16 0.15 enet 7 0.09 2.7e-03 6.1 -5.3 8.7e-08 -0.04 0.00 0.95 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma RMND1 0.06 0.04 blup 57 0.06 4.9e-05 4.2 -5.7 9.8e-09 -0.03 0.03 0.88 FALSE