[Hub]/) : Traits : Whole body water mass :

chr7:70,996,097-73,789,730

Best TWAS P=1.53e-15 · Best GWAS P=1.27e-15 conditioned to 0.0648

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 6.04 6.5 5.6e-11 0.36 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 6.96 7.6 2.8e-14 0.70 0.10 0.90 FALSE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 6.92 7.5 8.3e-14 0.67 0.34 0.62 FALSE
4 GTEx Adipose Visceral Omentum NSUN5 0.07 0.03 enet 11 0.04 4.0e-03 7.67 6.3 2.4e-10 0.48 0.05 0.44 FALSE
5 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 7.60 7.9 2.3e-15 0.77 0.06 0.94 FALSE
6 GTEx Heart Left Ventricle MLXIPL 0.14 0.00 enet 24 0.01 1.3e-01 0.52 5.8 8.2e-09 0.38 0.13 0.33 FALSE
7 GTEx Lung MLXIPL 0.10 0.07 enet 14 0.07 6.3e-06 6.96 5.7 1.4e-08 0.50 0.17 0.59 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 7.60 7.4 1.1e-13 0.62 0.06 0.89 FALSE
9 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 7.56 7.7 1.8e-14 0.69 0.12 0.88 FALSE
10 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 7.55 -7.7 1.3e-14 -0.88 0.02 0.65 FALSE
11 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 5.24 7.0 3.0e-12 0.58 0.04 0.24 FALSE
12 GTEx Testis VPS37D 0.15 0.01 lasso 5 0.03 2.7e-02 -5.01 -5.5 4.0e-08 -0.33 0.13 0.06 FALSE
13 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 6.96 8.0 1.5e-15 0.73 0.07 0.93 TRUE
14 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 7.70 7.9 2.1e-15 0.80 0.05 0.95 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 7.67 7.3 2.5e-13 0.77 0.00 1.00 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 7.67 7.7 1.8e-14 0.83 0.00 0.94 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 7.67 6.5 8.5e-11 0.70 0.00 0.99 FALSE
18 The Cancer Genome Atlas Skin Cutaneous Melanoma CALN1 0.37 0.04 enet 10 0.25 3.1e-07 -6.15 5.2 1.9e-07 0.05 0.01 0.96 TRUE
19 The Cancer Genome Atlas Thyroid Carcinoma BCL7B 0.05 0.01 blup 5 0.03 1.3e-03 7.67 -6.7 1.9e-11 -0.93 0.00 0.63 FALSE