[Hub]/) : Traits : Whole body water mass :

chr10:69,348,758-70,981,217

Best TWAS P=4.46e-16 · Best GWAS P=3.57e-15 conditioned to 0.0125

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DNA2 0.31 0.23 enet 10 0.25 2.3e-20 -4.8 5.3 1.5e-07 0.29 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum DNA2 0.32 0.18 lasso 9 0.20 1.9e-10 -5.8 5.8 6.9e-09 0.34 1.00 0.00 FALSE
3 GTEx Adrenal Gland DNA2 0.16 0.12 lasso 6 0.10 2.2e-04 -4.8 5.4 7.3e-08 0.31 0.47 0.08 FALSE
4 GTEx Artery Aorta DNA2 0.22 0.17 lasso 6 0.16 5.1e-09 -4.8 5.5 3.7e-08 0.32 1.00 0.00 FALSE
5 GTEx Artery Coronary DNA2 0.12 0.12 lasso 5 0.12 5.3e-05 -5.8 6.2 6.3e-10 0.35 0.29 0.24 FALSE
6 GTEx Artery Tibial DNA2 0.10 0.09 lasso 3 0.11 4.4e-09 -5.8 5.4 5.8e-08 0.31 0.99 0.00 FALSE
7 GTEx Brain Caudate basal ganglia PBLD 0.17 0.14 lasso 16 0.13 1.2e-04 -4.8 -5.5 4.8e-08 -0.28 0.64 0.03 FALSE
8 GTEx Brain Cerebellar Hemisphere DNA2 0.28 0.29 lasso 11 0.27 1.4e-07 -4.8 5.3 1.3e-07 0.30 0.71 0.03 FALSE
9 GTEx Brain Cerebellum SLC25A16 0.22 0.15 lasso 9 0.19 2.2e-06 -4.8 -5.4 6.0e-08 -0.33 0.32 0.06 FALSE
10 GTEx Brain Cerebellum DNA2 0.45 0.47 lasso 3 0.47 1.0e-15 -4.8 5.2 2.5e-07 0.28 1.00 0.00 FALSE
11 GTEx Brain Hypothalamus SLC25A16 0.20 0.19 lasso 5 0.14 3.6e-04 -5.8 -5.8 5.3e-09 -0.32 0.15 0.05 FALSE
12 GTEx Breast Mammary Tissue DNA2 0.30 0.26 lasso 7 0.26 8.2e-14 -4.6 5.2 2.3e-07 0.29 1.00 0.00 FALSE
13 GTEx Breast Mammary Tissue (Male) DNA2 0.32 0.14 lasso 5 0.07 1.2e-02 -4.6 5.3 1.2e-07 0.30 0.33 0.06 FALSE
14 GTEx Breast Mammary Tissue (Female) DNA2 0.15 0.10 lasso 3 0.07 3.6e-03 -4.6 5.4 7.3e-08 0.31 0.16 0.21 FALSE
15 GTEx Cells EBV-transformed lymphocytes DNA2 0.32 0.14 lasso 2 0.10 2.9e-04 -5.8 5.8 6.1e-09 0.33 0.44 0.08 FALSE
16 GTEx Cells Transformed fibroblasts SLC25A16 0.10 0.02 enet 25 0.01 2.5e-02 -4.2 -6.2 5.1e-10 -0.54 0.70 0.20 FALSE
17 GTEx Colon Transverse DNA2 0.20 0.17 lasso 4 0.14 2.5e-07 -5.8 5.6 2.4e-08 0.33 0.78 0.21 FALSE
18 GTEx Esophagus Mucosa DNA2 0.32 0.12 lasso 4 0.17 2.1e-11 -5.8 5.2 2.5e-07 0.30 1.00 0.00 TRUE
19 GTEx Esophagus Muscularis DNA2 0.35 0.24 enet 10 0.33 9.3e-21 -5.8 5.5 4.8e-08 0.32 1.00 0.00 FALSE
20 GTEx Heart Atrial Appendage PBLD 0.08 0.02 lasso 2 0.02 6.1e-02 -7.2 -7.7 1.3e-14 -0.41 0.11 0.15 FALSE
21 GTEx Heart Left Ventricle DNA2 0.10 0.12 lasso 6 0.11 3.0e-06 -4.8 5.2 2.0e-07 0.29 0.88 0.05 FALSE
22 GTEx Lung DNA2 0.22 0.17 enet 12 0.24 3.9e-18 -5.8 5.8 4.8e-09 0.35 1.00 0.00 FALSE
23 GTEx Muscle Skeletal DNA2 0.18 0.16 lasso 4 0.19 1.7e-18 -4.8 5.4 6.5e-08 0.30 1.00 0.00 FALSE
24 GTEx Ovary DNA2 0.15 0.12 lasso 3 0.06 1.7e-02 -5.4 5.5 3.3e-08 0.34 0.12 0.06 FALSE
25 GTEx Pancreas DNA2 0.12 0.06 enet 9 0.08 4.1e-04 -4.6 6.2 7.4e-10 0.40 0.33 0.37 FALSE
26 GTEx Skin Not Sun Exposed Suprapubic DNA2 0.29 0.16 lasso 14 0.22 2.4e-12 -4.8 5.8 6.2e-09 0.32 1.00 0.00 FALSE
27 GTEx Spleen DNA2 0.35 0.19 lasso 8 0.15 1.3e-04 -5.8 5.3 1.4e-07 0.30 0.19 0.07 FALSE
28 GTEx Stomach DNA2 0.31 0.13 lasso 11 0.19 2.3e-09 -4.8 5.4 7.4e-08 0.32 0.92 0.08 FALSE
29 GTEx Testis SLC25A16 0.24 0.23 lasso 4 0.19 7.3e-09 -4.8 -5.2 2.0e-07 -0.29 0.99 0.01 FALSE
30 GTEx Thyroid DNA2 0.18 0.19 lasso 5 0.19 2.9e-14 -4.8 5.2 2.0e-07 0.29 1.00 0.00 FALSE
31 METSIM Adipose PBLD 0.16 0.15 lasso 12 0.14 6.4e-21 -4.8 -5.5 4.9e-08 -0.30 1.00 0.00 FALSE
32 NTR Blood SLC25A16 0.03 0.02 enet 16 0.03 1.7e-09 -5.8 -6.0 2.3e-09 -0.41 0.66 0.34 FALSE
33 ROSMAP Brain Pre-frontal Cortex PBLD 0.04 0.01 bslmm 388 0.02 1.3e-03 -4.0 -5.6 2.0e-08 -0.33 0.94 0.01 FALSE
34 ROSMAP Brain Pre-frontal Cortex SLC25A16 0.17 0.11 lasso 6 0.15 2.9e-19 -4.6 -6.1 8.8e-10 -0.33 0.90 0.10 FALSE
35 YFS Blood SLC25A16 0.09 0.13 lasso 3 0.13 6.8e-39 -5.8 -6.2 7.2e-10 -0.35 0.86 0.14 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma PBLD 0.06 0.07 lasso 2 0.04 2.3e-04 -6.5 -6.5 7.6e-11 -0.32 0.00 0.99 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma SLC25A16 0.01 0.02 lasso 2 0.01 5.5e-04 -5.8 -5.8 6.9e-09 -0.33 0.34 0.07 FALSE
38 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNA2 0.08 0.09 lasso 1 0.06 7.3e-04 -7.3 7.3 3.8e-13 0.39 0.00 0.99 FALSE
39 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATOH7 0.05 0.01 lasso 3 0.02 2.6e-03 -6.5 5.8 6.0e-09 0.26 0.01 0.81 FALSE
40 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PBLD 0.03 0.03 lasso 9 0.02 1.6e-03 -5.8 -5.9 4.3e-09 -0.26 0.02 0.82 FALSE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATOH7 0.16 0.06 enet 15 0.09 3.7e-10 -4.0 5.5 5.0e-08 0.28 0.04 0.96 FALSE
42 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PBLD 0.10 0.03 lasso 3 0.04 2.2e-05 -6.5 -6.1 8.8e-10 -0.31 0.00 0.99 FALSE
43 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ATOH7 0.08 0.04 enet 19 0.06 3.1e-04 -4.0 6.1 1.2e-09 0.24 0.03 0.86 FALSE
44 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNA2 0.05 0.00 blup 43 0.00 3.0e-01 -5.8 6.2 4.1e-10 0.39 0.01 0.84 FALSE
45 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PBLD 0.06 0.06 enet 6 0.06 2.5e-04 -5.3 -5.2 1.5e-07 -0.30 0.24 0.27 FALSE
46 The Cancer Genome Atlas Brain Lower Grade Glioma PBLD 0.12 0.18 enet 10 0.18 6.7e-20 -4.8 -5.7 1.2e-08 -0.35 0.19 0.81 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma SLC25A16 0.05 0.01 blup 42 0.02 2.9e-03 -5.8 -6.7 2.2e-11 -0.51 0.11 0.72 FALSE
48 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC25A16 0.02 0.02 enet 8 0.02 7.7e-04 -7.3 -7.0 3.6e-12 -0.38 0.07 0.25 FALSE
49 The Cancer Genome Atlas Prostate Adenocarcinoma PBLD 0.03 0.01 blup 76 0.01 1.3e-02 -5.7 -5.8 6.2e-09 -0.30 0.05 0.43 FALSE
50 The Cancer Genome Atlas Soft Tissue Sarcoma SLC25A16 0.07 0.03 blup 42 0.02 1.7e-02 -7.3 -8.1 4.5e-16 -0.53 0.09 0.38 TRUE
51 The Cancer Genome Atlas Testicular Germ Cell Tumors DNA2 0.14 0.07 blup 43 0.08 8.6e-04 -6.0 -6.3 2.1e-10 -0.39 0.08 0.47 FALSE
52 The Cancer Genome Atlas Thyroid Carcinoma SLC25A16 0.05 0.05 lasso 3 0.04 3.8e-05 -5.8 -6.0 2.1e-09 -0.36 0.27 0.19 FALSE