TWAS hub - ATOH7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.103	0.0320	3.2e-09	0.077	0.090	0.088	0.09	0.090	1.1e-09	4.3e-11	6.8e-11	4.5e-11	4.3e-11
2	ROSMAP	Brain Pre-frontal Cortex	0.141	0.0435	1.9e-06	0.012	0.059	0.067	0.06	0.019	9.8e-03	4.3e-08	5.3e-09	3.6e-08	1.6e-03
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.049	0.0320	5.8e-03	0.009	0.016	0.008	NA	0.019	3.1e-02	5.4e-03	3.8e-02	NA	2.6e-03
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.159	0.0699	7.5e-08	0.058	0.066	0.088	NA	0.082	4.1e-07	6.6e-08	3.7e-10	NA	1.7e-09
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.078	0.0390	3.5e-04	0.038	0.056	0.058	NA	0.048	2.9e-03	3.7e-04	3.1e-04	NA	1.0e-03
6	TCGA	Pancreatic Adenocarcinoma	0.097	0.0540	2.5e-03	-0.007	0.038	-0.006	NA	-0.006	8.3e-01	1.1e-02	7.0e-01	NA	6.8e-01
7	TCGA	Prostate Adenocarcinoma	0.021	0.0131	7.5e-03	0.014	0.001	-0.002	NA	0.003	1.0e-02	2.4e-01	6.0e-01	NA	1.3e-01
8	TCGA	Stomach Adenocarcinoma	0.048	0.0270	8.8e-04	0.049	0.036	0.044	NA	0.054	1.9e-04	1.2e-03	4.0e-04	NA	8.6e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Sitting height	10.8	76.9	127.7	8.7	2.7	7.4	9.3	11.3	10.3	8.9	8.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	9.8	11.4	16.3	-3.6	-1.8	-3.8	-2.8	-3.9	-3.8	-4.0	-2.7
Medication: Lansoprazole	7.7	8.8	11.5	-2.9	-2.4	-3.2	-2.7	-3.2	-3.4	-3.0	-2.9
Lung FVC	7.6	38.5	66.6	-6.2	-0.8	-6.5	-5.4	-8.2	-7.4	-6.2	-6.3
Height	6.7	128.2	219.0	9.8	4.2	11.6	13.0	14.8	12.7	10.6	10.8
Medication: Omeprazole	6.6	7.9	13.7	-2.8	-0.9	-2.3	-2.6	-3.7	-3.5	-3.5	-1.9
Medication: Omeprazole (e.g. Zanprol)	6.3	7.6	14.2	-2.5	-0.7	-3.1	-2.9	-3.8	-3.2	-3.1	-1.6
Standing height	5.8	58.0	114.5	6.0	0.6	8.1	8.9	10.7	8.4	7.6	6.3
Osteoporosis (self-reported)	5.8	7.2	10.9	-2.5	-1.8	-2.4	-3.3	-2.9	-2.7	-3.3	-2.2
Comparative height size at age 10	5.1	28.3	57.5	4.2	0.9	5.8	6.3	7.6	5.9	4.9	4.2
Forced expiratory volume in 1-second (FEV1), predicted	4.4	9.2	20.3	2.4	-0.4	2.5	3.5	4.5	3.9	3.0	2.2
Mean time to correctly identify matches	4.1	7.7	12.3	-2.9	-1.8	-2.4	-3.3	-3.5	-3.5	-2.5	-1.8
Taking other prescription medications	3.9	6.0	8.4	-1.8	-1.9	-2.8	-2.9	-2.7	-2.9	-2.5	-1.8
Trunk fat-free mass	3.6	20.6	42.6	2.1	-0.1	6.2	5.9	6.5	4.5	4.3	2.3
Chest pain or discomfort	3.6	5.2	9.8	-1.7	-1.5	-3.1	-2.4	-2.7	-2.3	-2.5	-1.5
Reaction Time	3.5	6.7	9.7	-2.9	-2.1	-2.0	-2.8	-2.9	-3.1	-2.6	-1.9
Trunk predicted mass	3.5	20.2	42.2	2.1	-0.2	6.2	5.9	6.5	4.4	4.2	2.2
Had major operations	3.4	4.0	8.1	1.5	1.1	1.3	2.9	2.2	1.9	2.8	1.8
Diverticular disease/diverticulitis (self-reported)	3.2	3.9	7.2	2.2	1.5	0.7	1.9	1.3	2.1	2.7	2.4
Whole body fat-free mass	3.2	18.4	37.6	2.2	0.1	5.9	5.5	6.1	4.3	4.0	2.3
Whole body water mass	3.2	18.2	37.0	2.2	0.0	5.8	5.5	6.1	4.3	4.1	2.3
Leg predicted mass (right)	3.0	15.8	31.1	2.5	0.4	5.2	4.7	5.6	4.3	3.8	2.5
Leg fat-free mass (left)	2.9	15.5	29.7	2.6	0.6	5.1	4.8	5.5	4.3	3.8	2.5
Leg predicted mass (left)	2.9	15.4	29.4	2.6	0.6	5.0	4.7	5.4	4.3	3.8	2.5
Leg fat-free mass (right)	2.9	15.6	30.8	2.5	0.4	5.2	4.7	5.5	4.3	3.8	2.5
Heart attack	2.7	3.5	7.1	2.4	0.8	0.1	1.6	1.5	2.1	2.7	2.3
Arm predicted mass (right)	2.7	13.8	26.8	1.5	0.1	5.2	5.1	5.2	3.5	3.7	1.7
Basal metabolic rate	2.7	15.1	29.2	2.2	0.4	5.1	5.1	5.4	4.0	3.7	2.3
Number of treatments/medications taken	2.6	4.6	7.5	-2.2	-1.6	-1.8	-2.2	-2.2	-2.7	-2.7	-1.4
Arm fat-free mass (right)	2.6	13.6	26.9	1.6	0.2	5.2	5.0	5.0	3.4	3.7	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.4	11.2	-2.1	0.2	-2.5	-1.9	-3.3	-2.9	-1.8	-2.4
Arm fat-free mass (left)	2.5	12.5	24.3	1.5	0.2	4.9	4.8	4.9	3.4	3.5	1.8
Heart attack/myocardial infarction (self-reported)	2.5	3.3	7.0	2.3	0.6	0.3	1.5	1.5	2.1	2.7	2.2
Medication for pain relief, constipation, heartburn	2.4	4.1	9.7	1.2	-0.5	2.2	2.4	3.1	2.4	2.1	0.4
Migraine (self-reported)	2.4	3.0	6.7	0.8	0.0	1.5	2.4	2.4	1.6	2.6	0.6
Chronic bronchitis/emphysema (father)	2.3	2.7	7.8	-1.2	-1.0	-2.8	-1.2	-1.9	-1.2	-2.1	-0.7
Arm predicted mass (left)	2.3	11.5	21.8	1.5	0.1	4.6	4.6	4.7	3.2	3.4	1.8
Medication: Ventolin 100micrograms inhaler	2.1	2.7	4.7	-1.1	-1.6	-2.2	-1.7	-1.8	-1.7	-1.9	-0.5
Mouth/teeth dental problems: Loose teeth	2.1	2.5	6.7	-1.0	-0.2	-2.6	-1.3	-1.8	-1.3	-2.2	-0.7
Leg pain on walking	2.1	2.6	4.8	1.9	1.2	0.3	1.8	1.6	1.8	1.5	2.2
Coronary Artery Disease (CAD)	2.0	2.4	7.9	-0.3	-0.3	-2.8	-2.1	-1.9	-1.3	-0.5	-0.9
Number of incorrect matches in round	2.0	3.3	6.8	-1.7	-0.4	-0.4	-2.4	-2.6	-2.4	-2.1	-0.8
Noisy workplace	2.0	2.5	10.6	-0.7	-0.7	-3.2	-1.3	-1.7	-1.1	-1.6	-0.1
Illnesses of father: None of the above (group 1)	2.0	2.5	3.5	1.9	1.2	1.3	1.6	1.8	1.7	1.8	1.2
Number of self-reported non-cancer illnesses	2.0	3.5	4.9	-1.7	-2.0	-2.0	-2.2	-1.9	-1.9	-1.9	-1.2
Bipolar Disorder (2011)	1.8	1.7	3.6	1.6	0.2	-1.1	1.2	0.8	1.3	1.6	1.9
HDL Cholesterol	1.8	3.1	6.4	-2.5	-2.2	-0.0	-0.8	-1.0	-1.9	-1.6	-2.4
Smoking Status	1.8	4.2	10.6	-0.8	1.1	-2.0	-2.7	-3.2	-2.1	-2.3	-0.6
Asthma	1.8	3.5	6.2	-1.7	-2.3	-1.2	-1.7	-1.6	-2.0	-2.5	-1.9
Smoking status: Previous	1.8	2.7	6.6	-0.5	1.8	-0.9	-2.2	-2.6	-1.3	-1.9	0.7
Alzheimer’s Disease (in mother)	1.7	2.0	4.2	-1.0	-0.1	-1.6	-1.9	-2.1	-1.5	-1.2	-0.9
Medication: Aspirin	1.7	2.3	4.0	-1.8	-0.5	-1.6	-1.2	-1.8	-2.0	-1.6	-1.2
Medication: Aspirin	1.7	2.2	3.6	-1.6	-0.6	-1.5	-1.3	-1.8	-1.9	-1.4	-1.2
Leg fat percentage (left)	1.7	6.0	15.9	-1.0	2.6	-3.6	-0.9	-4.0	-2.6	-1.9	-0.8
Cholesterol lowering medication	1.7	2.5	6.3	-0.7	0.3	-1.8	-2.3	-2.5	-1.6	-1.4	-0.2
Angina	1.6	2.1	3.1	-1.8	-0.6	-1.7	-0.9	-1.7	-1.7	-1.5	-1.2
Wheeze or whistling in the chest in last year	1.6	2.8	4.1	-1.4	-1.4	-1.6	-1.7	-2.0	-2.0	-1.8	-1.4
Pain type(s) experienced in last month: Hip pain	1.6	2.1	4.5	-1.5	0.3	-0.8	-1.3	-1.9	-1.7	-2.1	-0.7
Supplements: Calcium	1.6	1.8	3.7	-1.1	0.4	-0.8	-1.7	-1.9	-1.5	-1.9	-0.1
Time employed in main current job	1.5	1.7	4.6	-1.7	-1.0	-0.5	-0.4	-0.6	-1.5	-1.5	-2.1
Leg fat percentage (right)	1.5	5.6	14.8	-0.9	2.5	-3.5	-0.7	-3.8	-2.5	-1.7	-0.7
Qualifications: College or University degree	1.5	4.9	15.3	0.8	-1.5	3.9	1.5	3.2	1.9	2.1	0.2
Angina (self-reported)	1.5	2.0	3.3	-1.8	-0.5	-1.5	-0.9	-1.6	-1.8	-1.4	-1.2
Asthma (self-reported)	1.5	3.1	5.9	-1.6	-2.4	-0.9	-1.4	-1.2	-1.8	-2.3	-1.8
Alzheimer’s Disease (in father)	1.4	1.5	4.4	-1.1	-2.1	-1.5	-0.5	-0.4	-1.0	-0.5	-1.5
Medication for hormone replacement therapy	1.4	1.6	3.9	1.0	-0.3	0.2	1.8	2.0	1.7	1.1	0.7
Nervous feelings	1.4	2.6	6.3	-1.2	-1.7	-2.5	-1.3	-1.6	-1.5	-1.6	-1.1
Illnesses of father: Heart disease	1.4	2.0	3.2	-1.8	-0.5	0.1	-1.7	-1.4	-1.7	-1.7	-1.2
Long-standing illness, disability or infirmity	1.4	2.2	3.6	-1.0	-1.1	-1.4	-1.9	-1.9	-1.8	-1.7	-0.6
Medication for cholesterol	1.4	2.1	4.2	1.3	1.2	1.6	2.0	1.8	1.2	1.4	0.5
Fractured/broken bones in last 5 years	1.4	1.7	3.7	0.7	-0.4	1.6	1.9	1.6	1.0	1.8	0.2
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	2.9	-1.6	-1.0	-0.0	-1.7	-1.5	-1.7	-1.3	-0.9
Loud music exposure frequency	1.3	1.5	2.5	1.4	0.9	0.6	1.2	1.6	1.5	1.4	0.5
High blood pressure (siblings)	1.3	1.9	3.1	-1.7	-1.0	-1.1	-1.4	-1.2	-1.5	-1.5	-1.6
Exposure to tobacco smoke outside home	1.3	1.7	3.6	0.8	-0.1	1.5	1.9	1.6	1.4	1.4	0.5
Age at first live birth	1.3	2.2	5.1	1.5	0.7	0.9	2.3	2.0	1.6	1.2	1.1
Ever had bowel cancer screening	1.3	1.5	2.5	0.8	0.9	1.2	1.6	0.9	1.0	1.5	1.6
Ever had prostate specific antigen (PSA) test	1.3	1.5	4.0	1.9	0.5	0.0	0.7	1.0	1.6	0.6	2.0
Bipolar Disorder (2018)	1.2	2.0	4.6	1.8	0.4	0.0	0.8	1.0	1.9	2.2	1.6
Alzheimer’s Disease (including proxy)	1.2	1.8	4.0	-0.8	-0.7	-2.0	-1.5	-1.7	-1.4	-0.8	-1.3
Systolic blood pressure, automated reading	1.2	3.5	7.5	-1.2	2.1	-1.5	-1.9	-2.7	-1.8	-2.3	-0.2
Had menopause	1.2	1.5	6.2	-0.5	0.7	-2.5	-0.9	-1.8	-0.9	-0.6	0.3
Exposure to tobacco smoke at home	1.2	1.4	3.0	-0.7	-0.3	-1.3	-1.2	-1.5	-0.9	-1.7	-1.1
Eye problems/disorders: Cataract	1.2	1.4	3.5	0.8	-1.9	-0.0	1.0	1.7	1.3	0.9	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.8	1.0	0.7	0.8	1.7	0.9	1.0	1.5	1.5
Medication: Lisinopril	1.2	1.5	3.1	-1.1	-1.2	-1.8	-0.8	-1.6	-1.5	-1.0	-0.2
Prostate Cancer	1.1	1.6	3.0	1.6	0.6	-0.3	1.5	1.5	1.7	0.5	1.5
Age when periods started (menarche)	1.1	2.6	6.5	-2.1	-1.4	-1.2	-1.3	-1.3	-1.6	-0.6	-2.6
Multivitamins +/- minerals	1.1	1.4	3.3	-0.9	1.3	1.8	-0.9	-1.4	-1.2	-1.1	0.1
Past tobacco smoking	1.1	2.0	5.0	-0.1	-1.6	1.4	1.9	2.2	1.0	1.2	-1.0
Financial difficulties in last 2 years	1.1	1.5	5.0	1.5	2.2	0.1	1.1	0.2	0.9	1.2	1.1
Fluid intelligence score	1.1	2.2	4.0	1.4	0.6	2.0	1.3	1.5	1.7	1.5	1.6
Weight	1.1	5.5	11.6	1.7	1.5	2.5	3.4	2.7	2.2	2.2	2.0
Worrier / anxious feelings	1.1	2.0	3.6	-1.5	-1.9	-1.6	-0.6	-0.9	-1.6	-1.0	-1.8
Number of live births	1.1	1.5	3.5	-1.1	-0.8	-1.9	-1.3	-1.3	-1.2	-1.0	-0.9
Birth weight of first child	1.1	2.1	7.7	-2.1	-2.8	0.1	-0.4	0.1	-0.9	-0.5	-1.8
Intelligence (Savage-Jansen 2018)	1.0	2.9	8.1	0.3	-1.0	2.8	1.5	2.4	1.6	1.8	0.5
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.6	-1.4	-0.6	-0.5	-0.6	-1.2	-1.3	-2.1	-0.5
Pack years adult smoking proportion	1.0	1.5	2.8	-1.2	-1.3	-0.9	-1.3	-0.9	-0.9	-1.3	-1.7
Depression (self-reported)	1.0	1.1	2.4	-0.8	-0.8	-1.2	-0.6	-1.6	-1.4	-1.2	-0.5
Glaucoma (self-reported)	1.0	1.1	3.9	-0.3	-0.7	-2.0	-1.6	-1.3	-0.3	-0.2	-0.3
Schizophrenia vs Biploar Disorder	0.9	1.2	2.5	-1.4	0.5	-0.4	-0.8	-1.5	-1.6	-1.1	-1.0
Respiratory disease	0.9	1.9	4.1	-1.7	-1.1	0.3	-1.1	-1.1	-1.7	-2.0	-1.3
Type 2 Diabetes (T2D) (2018)	0.9	1.8	3.8	1.9	1.6	-1.5	0.4	0.1	1.2	1.3	1.5
Current tobacco smoking	0.9	1.5	3.9	-0.5	-1.0	-2.0	-1.4	-1.3	-1.1	-0.6	-1.5
Qualifications: None of the above	0.9	1.9	6.6	-0.3	1.4	-2.6	-1.2	-1.9	-1.1	-0.5	-0.4
Allergy	0.9	2.1	7.5	1.4	0.5	0.2	1.4	1.5	1.6	2.7	0.7
Diabetes (self-reported)	0.9	1.4	2.8	1.7	1.0	-0.4	0.9	0.6	1.3	1.7	1.3
Illnesses of mother	0.9	1.1	2.0	1.2	0.6	0.8	1.4	1.3	1.2	1.1	0.5
Medication: Paracetamol	0.9	1.5	3.5	0.3	1.7	-0.9	-1.2	-1.9	-0.8	-1.1	1.1
Health satisfaction	0.9	1.1	5.1	0.8	0.6	0.3	1.3	0.5	0.7	0.6	2.2
Heart disease (mother)	0.9	1.1	2.2	-1.2	0.1	-1.4	-1.0	-1.5	-1.2	-0.8	-0.3
Pulse rate, automated reading	0.9	2.8	7.1	0.9	-2.7	-0.0	1.4	2.7	2.0	1.2	0.4
Illnesses of siblings: Diabetes	0.9	1.1	2.7	1.4	0.7	-0.5	0.6	0.6	1.2	1.1	1.6
Loneliness, isolation	0.9	1.3	3.1	-1.5	-1.2	-0.7	-0.4	-0.7	-1.1	-1.2	-1.8
Commuting to job workplace: Walk	0.9	1.0	2.8	-0.9	-0.2	-0.6	-1.7	-1.3	-0.9	-0.9	-0.8
Smoking status: Current	0.9	1.4	3.8	-0.3	-0.7	-1.9	-1.3	-1.4	-1.2	-0.3	-1.4
Average weekly champagne plus white wine intake	0.9	1.2	2.4	0.8	0.3	1.4	1.5	1.1	0.9	0.6	1.6
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	0.1	1.5	-1.1	-0.7	-1.5	-0.9	-1.1	1.0
Medication: Atorvastatin	0.9	1.2	3.1	-0.3	-0.2	-1.3	-1.8	-1.5	-1.0	-0.9	-0.5
Age started oral contraceptive pill	0.9	1.1	2.9	-0.7	0.3	-0.9	-1.0	-1.7	-1.2	-1.4	0.2
HbA1C	0.8	0.9	2.2	1.4	0.9	-0.5	0.1	0.2	0.4	1.5	1.3
Type 2 Diabetes (T2D) (2012)	0.8	1.0	2.9	1.0	1.7	0.6	0.9	0.3	0.7	0.4	1.4
Cardiovascular Disease	0.8	2.6	7.0	-1.3	-0.8	-1.6	-2.6	-2.0	-1.5	-1.5	-0.5
Vitamin and mineral supplements	0.8	1.0	1.8	0.8	-0.7	-1.1	0.8	1.3	1.2	1.3	-0.5
Hand grip strength (right)	0.8	2.1	5.6	0.3	2.2	2.4	2.0	0.7	0.6	1.3	0.6
Serious illness, injury or assault to yourself	0.8	0.9	2.3	0.9	0.5	-0.1	1.5	0.6	0.8	1.4	0.9
Mouth/teeth dental problems	0.8	1.2	2.2	0.8	0.1	1.3	0.6	1.5	1.2	1.4	1.0
Alcohol intake versus 10 years previously	0.8	1.2	2.0	1.0	1.3	0.8	0.8	1.0	1.4	0.5	1.4
Prospective memory result	0.8	1.0	1.8	-1.4	0.2	0.9	-0.3	-0.7	-1.3	-1.3	-1.0
Worry too long after embarrassment	0.8	1.3	2.4	1.5	-1.0	-0.7	1.0	1.2	1.3	1.4	1.0
Eye problems/disorders: None of the above	0.8	0.9	4.2	-0.2	2.0	0.2	-0.2	-1.4	-0.8	-0.6	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.9	1.1	0.4	0.5	1.0	1.4	1.4	0.3	1.0
Number of full sisters	0.8	1.0	3.8	-0.4	-0.6	-1.2	-2.0	-0.9	-0.4	-1.2	-0.1
Family relationship satisfaction	0.8	1.0	3.1	-1.8	-0.9	0.7	-0.4	-0.6	-1.3	-1.1	-0.7
Knee pain experienced in last month	0.8	1.2	2.3	1.4	1.5	-0.9	0.5	0.2	1.1	1.1	1.4
Osteoarthritis (self-reported)	0.8	1.0	3.4	-1.3	-1.8	-0.6	-0.4	-0.5	-0.7	-1.1	-0.8
Medication: Blood pressure	0.8	1.6	5.2	-0.6	-0.1	-1.3	-2.3	-1.8	-1.0	-1.1	-0.0
Medication: Paracetamol	0.8	1.2	3.0	0.4	1.7	-0.7	-0.9	-1.6	-0.7	-0.8	1.3
Basal cell carcinoma (self-reported)	0.8	1.0	2.0	-1.2	-0.8	-0.6	-1.4	-0.6	-0.8	-1.4	-0.9
Breast Cancer	0.7	1.7	3.5	-1.4	-0.3	-0.2	-1.3	-1.8	-1.7	-1.9	-0.2
Mean Putamen Volume	0.7	0.8	1.9	-1.0	-1.1	-0.8	-1.4	-0.5	-0.4	-0.7	-0.9
Maternal smoking around birth	0.7	1.0	2.2	1.2	-0.0	-0.3	0.8	1.5	1.4	1.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.0	-0.9	0.6	-0.5	-1.2	-1.4	-1.0	-1.4	-0.3
Medication: Simvastatin	0.7	1.0	3.4	-0.6	0.4	-1.9	-0.8	-1.5	-1.0	-0.7	0.1
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.4	1.6	0.9	-0.9	-0.1	-0.2	0.6	0.3	1.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.9	0.4	-1.2	0.2	1.3	1.7	1.1	0.9	0.6
Headache pain in last month	0.7	1.3	2.3	-1.5	-1.2	0.9	-0.8	-0.7	-1.3	-1.2	-1.3
Body fat percentage	0.7	2.6	6.9	0.3	2.5	-2.6	-0.2	-2.4	-1.1	-0.7	0.4
Diabetes diagnosed by doctor	0.7	1.1	1.8	1.4	0.8	-1.3	0.9	0.5	1.0	1.4	0.9
Qualifications: nursing, teaching	0.7	1.1	6.0	-0.3	-0.4	2.5	0.7	1.1	0.1	0.8	-0.6
Back pain experienced in last month	0.7	1.0	3.7	-1.2	-0.9	0.4	-0.4	-0.6	-1.1	-1.9	-0.3
Mineral and other dietary supplements	0.7	0.9	2.5	-0.1	-1.6	0.4	0.4	1.1	0.6	0.8	-1.4
High cholesterol (Self-reported)	0.7	1.2	3.8	-0.3	0.1	-1.9	-1.4	-1.6	-0.8	-0.8	-0.4
Ever smoked	0.7	1.2	3.6	0.8	1.2	-1.9	-1.3	-1.2	-0.1	-0.3	0.9
Pain experienced in last month	0.7	1.1	2.8	0.6	-0.1	1.1	1.1	1.7	1.1	1.5	-0.2
Pack years of smoking	0.7	1.1	1.6	-1.1	-0.8	-0.7	-1.2	-1.0	-0.9	-1.1	-1.3
Worry (Nagel 2018)	0.6	1.3	5.6	-0.6	-2.4	-1.7	0.0	0.1	-0.4	-0.5	-1.2
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.8	0.4	0.5	2.2	1.1	1.2	1.3	0.9	1.3
Primary Biliary Cirrhosis	0.6	0.9	2.1	1.1	1.5	0.1	1.1	0.4	0.6	0.9	1.0
Systolic Blood Pressure	0.6	3.1	5.9	-0.8	1.0	-2.2	-2.4	-2.1	-1.3	-2.3	-0.3
Hand grip strength (left)	0.6	1.5	5.3	-0.1	1.4	2.3	1.7	0.9	0.3	1.0	0.3
Relative age of first facial hair	0.6	1.2	3.2	1.5	1.5	0.2	0.1	0.3	1.1	0.9	1.8
Diabetes (mother)	0.6	0.8	1.4	-0.9	-0.8	-1.1	-0.2	-0.6	-1.0	-0.9	-1.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.5	-1.2	-1.2	-0.8	-0.0	-0.3	-0.9	-1.0	-0.5
High blood pressure	0.6	1.8	4.6	-1.3	-0.7	-1.1	-2.1	-1.4	-1.2	-1.5	-0.7
Supplements: Glucosamine	0.6	0.7	3.1	0.5	1.4	0.2	-0.3	-0.8	-0.1	-0.1	1.8
Impedance of leg (left)	0.6	2.9	13.0	-0.1	0.5	-3.6	-0.9	-2.2	-1.4	-1.2	-0.3
Father’s age at death	0.6	0.9	2.0	-0.6	-0.7	-0.8	-1.4	-1.3	-1.0	-0.9	-0.1
Pulse rate	0.6	1.0	6.3	-0.5	-2.5	-0.1	-0.1	1.0	0.4	0.0	-0.6
Breastfed as a baby	0.6	0.7	2.4	0.9	0.4	-1.6	0.1	-0.4	0.4	0.3	1.5
Blood clot in the leg (DVT)	0.6	0.7	1.6	1.2	0.3	-0.8	-0.1	0.5	1.2	1.3	0.5
Gout (self-reported)	0.6	0.9	2.3	-0.6	0.1	-1.5	-0.9	-1.2	-0.9	-1.0	-0.4
Number of full brothers	0.6	0.8	2.2	1.3	0.5	0.1	-0.4	0.7	1.5	0.7	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.5	0.6	1.6	0.8	0.1	-0.1	0.6	-0.1	1.3
Neck or shoulder pain in last month	0.6	0.8	3.0	-0.1	-0.6	-1.7	-0.5	-1.0	-0.5	-1.2	0.1
Suffer from ‘nerves’	0.6	0.9	4.4	0.0	-1.1	-2.1	-0.6	-0.8	-0.2	-0.6	0.2
Arm fat percentage (left)	0.6	2.2	5.8	-0.3	2.0	-2.1	-0.4	-2.4	-1.5	-1.1	-0.3
Medication: Gliclazide	0.6	0.7	2.3	1.5	0.4	-0.0	-0.0	0.5	0.9	1.1	0.9
Alcohol drinker status: Never	0.6	0.7	1.7	-0.8	-1.0	0.8	1.3	0.8	-0.5	-0.1	-0.7
Irritability	0.6	1.0	2.4	1.5	-0.4	1.0	0.4	1.2	1.3	0.9	0.6
Ever depressed for a whole week	0.6	0.8	1.8	-0.4	-0.3	-1.3	-1.0	-1.3	-0.8	-0.9	0.3
Unable to work because of sickness or disability	0.6	0.7	1.3	-0.9	0.4	-0.7	-0.3	-0.8	-1.1	-1.1	-1.1
Bipolar Disorder or Schizophrenia	0.5	1.3	3.3	1.5	-0.2	-0.5	0.2	1.0	1.5	1.8	1.0
Depression (Nagel 2018)	0.5	0.7	2.9	-0.9	0.1	0.2	-0.1	-0.6	-1.1	-1.7	-0.5
LDL Cholesterol	0.5	0.9	1.8	0.7	0.8	-0.5	-1.4	-1.1	-0.1	-0.8	1.3
Triglycerides	0.5	0.8	1.9	1.0	0.9	-1.2	-0.8	-0.8	0.5	0.0	1.4
Blood Red Count	0.5	4.4	6.8	2.3	1.7	1.1	2.1	1.8	2.4	2.6	2.4
Heel T-Score	0.5	3.9	6.3	1.7	1.8	2.0	2.5	1.8	1.9	2.2	1.8
Diabetes (father)	0.5	0.6	3.9	0.3	0.3	-2.0	-0.3	-0.8	-0.2	-0.4	0.4
Relative age voice broke	0.5	0.8	1.1	1.0	1.0	0.4	1.1	0.7	0.8	0.8	0.9
Hayfever, allergic rhinitis or eczema	0.5	1.1	4.7	-1.1	-0.4	0.8	-0.5	-0.7	-1.1	-2.2	-0.3
Pain all over the body in last month	0.5	0.5	1.0	-0.7	0.5	0.4	-0.7	-1.0	-1.0	-0.7	-0.4
Arm fat percentage (right)	0.5	2.1	5.6	-0.0	2.0	-2.2	-0.5	-2.4	-1.3	-1.0	-0.1
Medication: Cholesterol lowering	0.5	0.7	1.8	-0.9	-0.1	-1.3	-0.4	-1.0	-1.0	-0.7	-0.7
Pulse wave Arterial Stiffness index	0.5	0.6	1.7	0.9	0.3	0.1	0.4	0.6	1.0	1.3	0.9
Length of working week for main job	0.5	0.6	2.4	-0.8	-1.5	0.5	0.6	0.5	-0.1	-0.3	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.0	-0.7	-0.5	-1.4	-0.3	-1.4	-1.4	-1.2	-0.2
Emphysema/chronic bronchitis	0.5	0.6	1.2	-1.1	-0.7	-0.7	-0.6	-0.7	-1.0	-0.5	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	3.0	0.0	-0.3	-1.7	-0.5	-0.8	-0.0	-1.2	-0.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.8	0.5	1.4	-0.1	0.8	-0.2	0.2	0.4	1.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	-0.6	-1.2	-0.9	-1.0	-0.6	-0.5	-0.8	-0.1
Financial situation satisfaction	0.5	0.6	2.1	0.3	-0.2	0.7	1.4	1.0	0.7	0.6	0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.5	-0.1	0.5	-1.6	-0.7	-1.0	-0.3	-0.8	0.2
Vascular/heart problems diagnosed by doctor	0.5	1.4	3.8	0.9	0.9	1.6	1.9	1.2	0.9	1.1	0.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.8	1.0	0.1	-1.3	-0.5	0.1	0.8	1.1	0.1
Depressed Affect (Nagel 2018)	0.4	0.7	1.9	0.5	-0.7	0.3	1.4	1.3	1.0	0.7	0.3
Major Depression (MDD)	0.4	0.5	1.2	-1.1	-0.9	-0.4	-0.9	-0.3	-0.6	-0.7	-0.1
Fasting Glucose	0.4	0.4	1.5	0.2	1.2	0.4	0.9	-0.1	0.0	-0.9	0.5
Neuroticism (2016)	0.4	0.5	2.2	0.9	0.9	-0.0	0.3	0.2	0.5	0.2	1.5
Rheumatoid Arthritis	0.4	0.5	1.1	0.8	0.3	-1.0	0.3	0.5	0.7	0.6	1.0
Blood Eosinophil Count	0.4	2.8	5.3	-1.9	-2.3	-1.2	-0.9	-0.8	-1.4	-1.8	-2.2
Hypothyroidism (self reported)	0.4	0.8	2.2	-0.8	0.3	-0.8	-0.3	-1.2	-1.3	-1.5	-0.2
Medication: Co-codamol	0.4	0.5	1.7	0.3	1.3	-0.5	0.1	-0.5	-0.1	-0.6	1.2
Impedance of leg (right)	0.4	2.1	10.8	0.2	0.5	-3.3	-0.7	-1.8	-1.1	-0.9	-0.0
Trunk fat percentage	0.4	1.7	4.8	0.9	2.2	-2.1	0.1	-1.6	-0.4	-0.2	0.8
Average weekly fortified wine intake	0.4	0.4	1.2	0.7	-0.3	-1.1	-0.1	-0.3	0.1	1.1	0.7
Medication: Atenolol	0.4	0.6	1.4	-0.2	-1.2	-1.2	-0.6	-0.8	-0.4	-0.0	0.6
Medication: Levothyroxine sodium	0.4	0.6	1.3	-0.7	-0.4	-1.0	-0.3	-0.9	-1.1	-1.1	-0.3
Body mass index (BMI)	0.4	1.8	5.1	-1.1	1.3	-1.2	-0.6	-2.2	-1.6	-1.2	-0.8
Trunk fat mass	0.4	1.7	4.3	1.4	2.1	-0.2	1.8	0.4	0.9	1.0	1.5
Had other major operations	0.4	0.5	0.9	-0.8	-0.4	-1.0	-0.9	-0.9	-0.7	-0.5	-0.4
Impedance of arm (right)	0.4	2.0	6.0	2.2	0.7	-2.4	-1.0	-0.4	0.8	0.1	1.7
Hip circumference	0.4	1.8	5.1	1.2	1.5	0.6	2.3	1.2	1.1	1.1	1.2
Qualifications: A levels/AS levels or equivalent	0.4	1.0	4.3	-0.5	-2.1	1.3	0.8	1.0	-0.2	0.0	-0.2
Lung cancer (father)	0.4	0.4	1.1	0.9	0.6	-0.6	-0.3	-0.1	0.5	0.4	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.1	-1.4	-0.4	-1.0	0.2	-1.1	-1.4	-1.0	-1.5
Tense / ‘highly strung’	0.4	0.6	2.1	0.9	-1.4	-0.4	0.2	0.9	0.9	0.2	0.3
Peak expiratory flow (PEF)	0.4	0.8	1.9	0.7	1.2	-0.9	1.1	0.2	0.8	0.3	1.4
Medication: Amlodipine	0.4	0.6	2.1	0.9	0.7	-0.5	-0.3	-0.2	0.6	0.6	1.5
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.0	0.6	-0.7	-0.1	0.6	1.0	0.9	0.8	0.2
Forced vital capacity (FVC), Best measure	0.4	1.5	2.8	-1.7	-0.8	-0.8	0.0	-0.9	-1.5	-1.3	-1.7
Whole body fat mass	0.4	1.5	5.4	1.2	2.3	-0.4	1.7	-0.0	0.6	0.8	1.2
Hypertension (Self-reported)	0.4	1.0	3.2	-1.1	-0.4	-0.5	-1.8	-1.0	-0.9	-0.9	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.3	-0.9	-0.2	-0.7	-0.4	-1.1	-1.1	-0.8	-1.0
Breast cancer (self-reported)	0.4	0.5	1.0	0.7	0.8	-0.6	1.0	0.2	0.3	0.9	0.6
Mother’s age at death	0.4	0.6	1.9	-0.4	-0.2	0.3	-1.4	-0.7	-0.8	-1.1	0.0
Commuting to job workplace: Cycle	0.4	0.5	3.3	0.2	0.0	1.8	-0.3	0.2	-0.1	0.1	0.9
Alcohol drinker status: Previous	0.4	0.4	1.2	-0.3	0.8	1.1	1.0	0.3	-0.3	0.0	-0.1
Neuroticism (Nagel 2018)	0.3	0.8	3.6	0.3	-1.9	-0.7	0.5	0.8	0.6	0.7	-0.5
Ovarian Cancer	0.3	0.3	0.9	-1.0	-0.3	0.7	0.3	0.3	-0.3	-0.2	-1.0
Age at First Birth	0.3	0.4	1.2	-0.5	-0.1	0.4	-0.6	-0.6	-1.1	-0.6	-0.9
Body Mass Index (BMI) (2010)	0.3	0.3	0.5	-0.6	-0.4	0.2	-0.5	-0.7	-0.6	-0.7	-0.7
Crohns Disease (2012)	0.3	0.5	1.5	0.6	-1.1	-1.2	0.4	0.4	0.3	0.9	0.1
Lupus	0.3	0.4	1.4	-0.1	-0.1	1.0	-0.8	0.4	-0.2	0.3	-1.2
Allergy or Eczema	0.3	0.7	3.3	-0.5	0.2	1.1	-0.4	-0.6	-0.8	-1.8	0.4
Neuroticism	0.3	0.8	1.5	0.9	-0.9	-0.5	1.2	1.0	0.9	1.1	0.2
Average weekly spirits intake	0.3	0.4	0.8	0.9	-0.3	-0.6	0.0	0.3	0.5	0.9	0.7
Hearing difficulty/problems: Yes	0.3	0.4	1.0	-0.2	1.0	-0.9	-0.4	-0.9	-0.4	-0.3	-0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.8	-0.9	-0.9	-0.7	0.3	-0.4	-0.6	-0.7	-0.1
Supplements: Zinc	0.3	0.3	1.1	-0.2	0.8	1.1	0.3	-0.2	-0.4	0.4	-0.0
Medication: Metformin	0.3	0.5	0.8	0.9	0.7	-0.5	0.6	0.8	0.7	0.7	0.6
Severe depression (siblings)	0.3	0.4	1.2	0.8	-0.6	-0.5	-0.5	0.2	0.4	0.4	1.1
Fed-up feelings	0.3	0.5	1.2	0.5	-0.3	-0.0	1.1	0.9	0.8	0.9	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.4	0.8	0.4	0.9	0.9	1.1	1.2	0.9	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.9	-0.1	0.0	-0.8	-0.7	-1.0	-0.6	-0.9	0.2
Hair/balding pattern: Pattern 2	0.3	0.3	0.6	0.6	0.3	-0.5	0.7	0.7	0.8	0.5	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	1.0	0.3	0.4	0.8	0.9	1.2	1.2	0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.4	-0.1	0.4	1.6	0.5	0.2	-0.1	-0.3	0.4
Illnesses of siblings	0.3	0.4	2.1	0.3	0.3	1.5	0.4	0.4	0.0	0.5	-0.2
Neuroticism score	0.3	0.6	2.2	0.7	-1.4	-1.5	0.1	0.3	0.5	0.4	0.1
Falls in the last year	0.3	0.4	1.0	0.8	-0.1	-0.1	0.5	0.6	0.8	1.0	0.5
Hair/balding pattern: Pattern 3	0.3	0.5	2.7	0.1	0.8	1.6	-0.2	0.4	0.4	0.2	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.9	-0.2	0.9	0.6	-0.1	-0.2	-0.2	-0.6	-1.0
Impedance of arm (left)	0.3	1.5	4.6	1.9	0.8	-2.1	-0.5	-0.2	0.7	0.1	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.9	0.3	0.7	-0.8	-0.7	-1.0	-0.2	-0.4	0.8
Pulse wave reflection index	0.3	0.4	1.9	0.6	1.4	0.2	0.2	0.0	0.4	0.2	0.7
Birth weight	0.3	0.6	1.8	-0.4	-1.1	1.3	0.4	1.1	0.4	0.0	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	0.5	0.3	1.2	0.6	0.3	0.2	-0.1	0.9
Number of children fathered	0.3	0.4	1.5	-0.3	-0.7	-1.2	-0.6	-0.1	0.1	-0.6	-0.3
Medication: Allopurinol	0.3	0.4	1.0	-0.2	1.0	-0.4	-0.2	-0.7	-0.6	-0.8	0.6
Medication: Seretide 50 evohaler	0.3	0.4	1.2	-0.7	-0.6	0.6	-0.2	-0.2	-0.5	-1.1	-0.7
Leg fat mass (right)	0.3	1.2	5.7	0.5	2.4	-0.8	1.5	-0.8	-0.2	0.3	0.6
Average weekly red wine intake	0.3	0.5	2.3	-0.1	-1.5	0.7	-0.5	0.1	-0.4	0.1	-0.6
Friendships satisfaction	0.3	0.3	0.9	-0.1	-0.9	-0.6	0.6	0.7	0.6	0.2	0.4
Miserableness	0.3	0.4	2.7	-0.2	-1.6	-0.6	-0.2	-0.1	-0.2	-0.3	-0.6
Commuting to job workplace: Public transport	0.3	0.3	0.6	0.4	-0.4	0.7	0.5	0.8	0.5	0.7	0.5
Medication: Bendroflumethiazide	0.3	0.5	2.0	0.2	0.4	1.2	0.2	-0.4	-0.1	0.1	1.4
Illnesses of father: High blood pressure	0.3	0.4	1.3	-1.1	0.1	0.2	-0.3	-0.1	-0.3	-1.1	-0.3
Number of operations (self-reported)	0.3	0.5	1.3	-0.1	-0.3	0.9	1.1	0.9	0.5	0.6	0.2
Average weekly beer plus cider intake	0.3	0.5	1.7	0.3	1.2	-1.3	0.7	-0.2	0.3	0.1	-0.2
Risk taking	0.3	0.4	1.0	0.9	0.4	-1.0	-0.3	0.3	0.8	-0.5	0.3
Impedance of whole body	0.3	1.6	6.9	1.6	0.6	-2.6	-0.6	-0.7	0.2	-0.0	1.3
Leg fat mass (left)	0.3	1.3	6.1	0.5	2.5	-0.9	1.4	-0.9	-0.2	0.2	0.7
Schizophrenia (2014)	0.2	0.4	1.4	0.7	-0.5	-1.2	-0.1	0.3	0.6	0.9	0.2
Ulcerative Colitis	0.2	0.2	0.4	-0.6	-0.2	-0.6	-0.3	-0.6	-0.6	-0.5	-0.2
BMI	0.2	1.1	3.4	-0.4	1.8	-0.6	-0.2	-1.8	-1.0	-0.4	-0.3
Lung FEV1/FVC ratio	0.2	0.9	2.1	1.0	0.7	0.3	0.9	0.3	0.8	1.4	1.3
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	-0.2	-0.8	-0.3	0.2	0.1	-0.1	-0.4	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.7	-0.5	-0.9	-0.5	0.6	0.0	-0.4	-0.1	-0.6
Townsend deprivation index at recruitment	0.2	0.3	0.8	-0.3	0.9	-0.4	-0.6	-0.8	-0.4	0.1	-0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	-0.3	-0.8	-0.3	-0.1	-0.2	-0.4	-0.0	-0.7
Qualifications: CSEs or equivalent	0.2	0.3	0.6	0.0	0.7	-0.2	0.8	-0.4	-0.6	-0.7	-0.3
Stomach or abdominal pain in last month	0.2	0.3	1.0	-0.3	0.1	-1.0	-0.4	-0.8	-0.5	-0.2	0.0
Waist circumference	0.2	0.7	2.9	0.8	1.7	-0.4	0.8	-0.5	0.1	0.2	0.9
Hearing difficulty/problems with background noise	0.2	0.3	1.2	0.1	-0.5	-1.1	-0.1	-0.4	-0.2	-0.6	0.2
Happiness	0.2	0.2	0.9	-1.0	-0.4	-0.3	0.2	-0.3	-0.5	-0.4	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.9	0.4	0.6	0.9	-0.2	-0.2	-0.0	-0.0	0.5
Arm fat mass (right)	0.2	0.7	3.2	0.6	1.8	-0.0	1.2	-0.2	0.2	0.4	0.6
Hair/balding pattern: Pattern 4	0.2	0.5	1.4	-0.1	-0.2	-0.9	-1.0	-1.2	-0.7	0.3	0.2
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.9	0.8	0.9	0.4	0.0	0.4	0.9	0.2	0.6
Comparative body size at age 10	0.2	0.7	2.6	0.0	1.6	0.3	-0.1	-1.2	-0.5	-0.6	0.9
Pulse wave peak to peak time	0.2	0.2	0.6	-0.4	-0.2	0.7	0.3	0.3	-0.4	-0.8	-0.4
Medication: Blood pressure	0.2	0.3	1.4	-0.3	-1.2	0.2	0.6	0.5	-0.2	0.5	-0.4
Overall health rating	0.2	0.5	2.6	-0.3	-0.4	-1.6	-0.2	-0.7	-0.6	-0.0	-0.7
Age at last live birth	0.2	0.2	1.0	0.2	0.1	0.2	1.0	0.6	0.4	0.6	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	-0.4	-0.7	0.7	-0.1	0.1	-0.0	-0.6	0.3
Mood swings	0.2	0.4	2.1	0.1	-1.5	-0.3	-0.8	0.2	0.1	0.0	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.6	0.4	0.2	0.1	-0.8	-0.1	0.6	0.3	0.2
Wears glasses or contact lenses	0.2	0.2	0.6	-0.8	-0.3	0.1	-0.2	-0.1	-0.6	-0.5	-0.6
Ever taken oral contraceptive pill	0.2	0.2	0.3	0.5	0.3	-0.5	-0.6	-0.4	0.5	-0.6	0.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.5	0.3	-0.5	-0.7	-0.5	0.2	0.5	0.6	0.5
Myopia	0.2	0.2	0.7	0.8	0.5	0.1	0.1	-0.5	-0.1	0.5	0.7
Heart disease (siblings)	0.2	0.3	1.0	-0.3	0.6	0.2	-0.6	-1.0	-0.7	0.3	-0.0
Schizophrenia (2018)	0.1	0.2	0.4	0.5	-0.5	-0.6	-0.3	0.4	0.4	0.6	0.1
Crohns Disease (2017)	0.1	0.2	1.0	0.2	-0.3	-0.5	1.0	0.1	-0.2	0.3	0.2
Irritable Bowel Disease (IBD)	0.1	0.1	0.6	0.3	-0.1	-0.5	0.8	0.0	-0.1	0.2	0.5
Blood Platelet Count	0.1	0.6	1.9	-0.0	-1.4	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7
Blood White Count	0.1	0.7	1.8	1.3	-1.0	-0.0	0.6	0.3	0.8	1.1	0.1
Waist Hip Ratio (WHR)	0.1	0.5	1.4	0.8	0.4	-1.2	-1.0	-0.8	0.2	-0.2	0.1
Chronotype (morning person)	0.1	0.3	0.6	-0.4	-0.5	0.5	0.3	0.7	0.6	0.8	0.5
Sensitivity / hurt feelings	0.1	0.2	0.5	0.2	-0.4	-0.5	0.1	0.3	0.2	0.7	-0.6
High blood pressure (mother)	0.1	0.2	0.8	-0.4	-0.9	0.2	-0.7	0.1	-0.1	0.0	-0.2
Alcohol usually taken with meals	0.1	0.2	0.9	0.3	-0.0	0.9	-0.3	0.5	0.6	0.2	0.5
Forced vital capacity (FVC)	0.1	0.5	1.6	-0.9	-0.4	-1.3	0.3	-0.4	-0.6	-0.7	-0.9
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	0.4	-0.1	0.1	0.4	0.1	0.2	0.6	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	-0.1	-0.1	0.4	-0.3	-0.4	-0.4	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.9	-0.6	-0.1	-0.9	0.6	-0.2	-0.2	-0.2	-0.5
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	-0.7	0.3	0.6	0.0	-0.1	-0.5	-0.6	-0.7
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.8	0.4	0.0	-0.9	0.3	-0.3	0.1	-0.4	0.1
Shortness of breath walking on level ground	0.1	0.2	0.3	-0.1	-0.4	-0.5	-0.3	-0.2	-0.5	-0.6	-0.5
Medication: Ibuprofen	0.1	0.2	0.9	0.1	0.0	1.0	-0.2	-0.3	-0.3	-0.4	0.3
Alcohol intake frequency.	0.1	0.3	1.1	-0.6	0.2	0.9	1.1	0.5	-0.1	0.1	-0.3
Supplements: Vitamin C	0.1	0.2	0.4	-0.1	-0.6	0.0	-0.5	-0.5	-0.4	-0.3	0.2
Arm fat mass (left)	0.1	0.5	2.4	0.4	1.6	-0.2	1.1	-0.2	0.1	0.3	0.4
Guilty feelings	0.1	0.1	0.3	0.4	-0.1	-0.5	-0.5	-0.2	0.3	0.4	-0.1
Hearing aid user	0.1	0.1	0.4	0.3	0.3	0.3	0.6	0.4	0.2	0.3	-0.1
Diastolic blood pressure, automated reading	0.1	0.3	0.8	-0.3	0.1	-0.9	-0.3	-0.5	-0.0	-0.7	0.6
Ulcerative Colitis (UC)	0.0	0.1	0.2	0.2	0.4	-0.2	0.2	-0.1	-0.1	0.2	0.2
Hair Pigment	0.0	1.2	2.7	-0.6	-0.7	-1.6	-1.0	-1.3	-1.1	-0.6	-1.4
Tanning	0.0	0.2	0.8	-0.5	-0.3	-0.9	0.1	-0.3	-0.7	-0.0	-0.3
Medication: Ramipril	0.0	0.1	0.2	-0.1	0.2	0.4	-0.3	0.1	-0.1	0.1	-0.4

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