[Hub]/) : Traits : Whole body water mass :

chr13:47,822,976-52,109,040

Best TWAS P=7.63e-29 · Best GWAS P=2.48e-64 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLEU7 0.05 0.00 blup 581 0.02 1.6e-03 1.50 7.3 3.2e-13 -0.46 0.08 0.21 TRUE
2 CommonMind Brain Pre-frontal Cortex EBPL 0.34 0.16 bslmm 399 0.33 2.5e-41 0.34 -6.5 9.8e-11 0.04 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex TRIM13 0.15 0.04 lasso 5 0.12 1.1e-14 8.43 -6.3 3.8e-10 0.22 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum EBPL 0.27 0.03 enet 17 0.20 1.4e-10 8.00 -6.0 1.6e-09 0.09 0.88 0.01 FALSE
5 GTEx Artery Aorta EBPL 0.43 0.20 enet 78 0.28 8.1e-16 6.38 -6.6 3.8e-11 0.14 1.00 0.00 FALSE
6 GTEx Artery Coronary EBPL 0.48 0.03 enet 99 0.12 9.7e-05 8.00 -5.5 4.0e-08 0.04 0.29 0.04 FALSE
7 GTEx Artery Tibial RCBTB2 0.14 0.01 enet 10 0.07 6.4e-06 1.59 -5.2 1.7e-07 -0.06 0.01 0.08 TRUE
8 GTEx Brain Caudate basal ganglia EBPL 0.41 0.06 lasso 7 0.12 2.1e-04 6.30 -5.7 1.1e-08 0.02 0.11 0.17 FALSE
9 GTEx Brain Cerebellar Hemisphere EBPL 0.54 0.32 enet 17 0.34 1.2e-09 0.34 -5.5 3.1e-08 0.08 0.65 0.02 FALSE
10 GTEx Brain Cerebellum EBPL 0.50 0.30 enet 23 0.36 1.8e-11 8.00 -7.0 3.7e-12 0.05 0.86 0.01 FALSE
11 GTEx Brain Cortex EBPL 0.36 0.08 enet 24 0.14 1.5e-04 8.00 -6.3 2.8e-10 0.14 0.18 0.15 FALSE
12 GTEx Brain Nucleus accumbens basal ganglia EBPL 0.25 0.11 enet 21 0.11 7.9e-04 6.41 -5.8 4.8e-09 0.12 0.13 0.09 FALSE
13 GTEx Brain Putamen basal ganglia EBPL 0.31 -0.01 enet 18 0.05 2.9e-02 6.41 -5.7 1.1e-08 0.08 0.06 0.13 FALSE
14 GTEx Breast Mammary Tissue (Female) SUCLA2 0.07 0.13 lasso 4 0.04 2.9e-02 5.16 -5.3 1.2e-07 -0.01 0.02 0.64 TRUE
15 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 6.30 -6.5 6.3e-11 0.02 1.00 0.00 FALSE
16 GTEx Esophagus Muscularis EBPL 0.39 0.16 enet 36 0.29 9.2e-18 6.38 -6.1 9.8e-10 0.03 1.00 0.00 FALSE
17 GTEx Heart Atrial Appendage EBPL 0.17 0.04 lasso 5 0.05 2.2e-03 8.00 -5.5 3.0e-08 0.07 0.26 0.03 FALSE
18 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 8.68 9.0 2.5e-19 -0.11 0.51 0.02 TRUE
19 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 8.00 -6.9 6.7e-12 0.07 0.38 0.04 FALSE
20 GTEx Pituitary EBPL 0.44 0.32 enet 29 0.37 3.1e-10 6.38 -6.0 2.3e-09 -0.02 0.92 0.01 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 6.38 -5.9 3.3e-09 0.00 1.00 0.00 FALSE
22 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 6.83 -7.0 2.7e-12 0.02 1.00 0.00 FALSE
23 GTEx Spleen RCBTB1 0.37 0.02 lasso 5 0.04 3.5e-02 0.66 -6.2 4.9e-10 0.01 0.04 0.10 FALSE
24 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 6.56 -7.6 2.4e-14 0.03 1.00 0.00 FALSE
25 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 6.30 -6.7 2.0e-11 0.08 1.00 0.00 TRUE
26 METSIM Adipose EBPL 0.32 0.12 lasso 7 0.27 1.4e-39 6.56 -5.6 2.0e-08 0.03 1.00 0.00 FALSE
27 NTR Blood DLEU7 0.07 0.02 enet 22 0.06 1.3e-19 -7.28 -11.1 7.6e-29 0.61 0.11 0.89 TRUE
28 ROSMAP Brain Pre-frontal Cortex EBPL 0.43 0.28 lasso 8 0.43 7.3e-60 6.30 -5.9 3.5e-09 0.03 1.00 0.00 FALSE
29 The Cancer Genome Atlas Breast Invasive Carcinoma EBPL 0.07 0.03 enet 11 0.06 2.1e-12 6.41 -5.5 3.1e-08 0.04 0.06 0.94 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DLEU2 0.08 0.02 lasso 2 0.01 1.6e-02 -5.73 6.2 6.1e-10 0.02 0.13 0.25 FALSE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EBPL 0.21 0.14 enet 15 0.19 3.6e-21 -1.29 -5.4 6.4e-08 0.08 1.00 0.00 TRUE
32 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EBPL 0.27 0.16 blup 59 0.22 1.0e-12 -1.29 -6.2 5.5e-10 0.06 0.29 0.71 TRUE
33 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 8.57 8.6 1.3e-17 -0.10 0.01 0.96 FALSE
34 The Cancer Genome Atlas Pancreatic Adenocarcinoma EBPL 0.21 0.09 enet 10 0.13 4.9e-06 8.00 -6.9 5.6e-12 0.07 0.00 1.00 FALSE
35 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 6.41 -7.1 1.7e-12 0.06 0.01 0.98 TRUE
36 The Cancer Genome Atlas Prostate Adenocarcinoma EBPL 0.08 0.01 blup 59 0.04 6.4e-05 6.41 -6.4 1.4e-10 0.04 0.01 0.89 TRUE
37 The Cancer Genome Atlas Stomach Adenocarcinoma EBPL 0.10 0.07 enet 7 0.08 2.8e-06 8.00 -6.1 1.3e-09 0.12 0.00 1.00 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma EBPL 0.28 0.10 enet 17 0.26 7.7e-25 -1.29 -5.8 7.2e-09 0.02 0.24 0.76 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma TRIM13 0.04 0.00 blup 26 0.02 8.5e-03 8.72 -7.5 6.8e-14 0.06 0.00 0.46 FALSE