Best TWAS P=3.26e-10 · Best GWAS P=5.2e-10 conditioned to 0.000555
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | RP11-23P13.6 | 0.07 | 0.00 | lasso | 5 | 0.01 | 9.6e-02 | -2.8 | 5.2 | 2.3e-07 | 0.66 | 0.05 | 0.55 | TRUE |
| 2 | YFS | Blood | MGA | 0.01 | 0.00 | blup | 454 | 0.00 | 7.1e-02 | -3.7 | -5.5 | 4.6e-08 | -0.27 | 0.12 | 0.10 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CHP | 0.06 | 0.01 | blup | 54 | 0.03 | 4.7e-04 | -3.7 | 6.3 | 3.3e-10 | 0.03 | 0.03 | 0.17 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CHP | 0.21 | 0.11 | lasso | 4 | 0.12 | 5.1e-13 | -5.0 | 5.4 | 5.8e-08 | 0.08 | 0.00 | 1.00 | FALSE |