Best TWAS P=4.9e-08 · Best GWAS P=2.47e-06 conditioned to 0.000432
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | DOPEY2 | 0.05 | 0.01 | blup | 115 | 0.02 | 5.6e-03 | -3.6 | -5.2 | 1.8e-07 | -0.35 | 0.02 | 0.05 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CBR1 | 0.45 | 0.09 | lasso | 5 | 0.22 | 5.1e-13 | 2.8 | -5.5 | 4.9e-08 | 0.01 | 0.02 | 0.74 | TRUE |