Hub : Genes

DOPEY2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1320	0.0320	5.6e-08	0.052	0.073	0.084	0.077	0.080	5.3e-07	3.4e-09	2.2e-10	1.3e-09	5.0e-10
2	GTEx	Artery Aorta	0.1660	0.0530	6.7e-04	-0.005	NA	0.017	NA	0.003	8.3e-01	NA	3.7e-02	NA	2.1e-01
3	GTEx	Artery Tibial	0.1860	0.0501	7.2e-05	0.044	NA	0.015	NA	0.027	2.2e-04	NA	2.3e-02	NA	3.2e-03
4	GTEx	Cells Transformed fibroblasts	0.3540	0.0590	1.6e-09	0.044	NA	0.180	NA	0.142	3.0e-04	NA	1.7e-13	NA	8.7e-11
5	GTEx	Esophagus Mucosa	0.4550	0.0610	5.0e-15	0.307	NA	0.323	NA	0.326	6.1e-21	NA	3.5e-22	NA	2.1e-22
6	GTEx	Heart Left Ventricle	0.2422	0.0785	3.4e-03	0.159	NA	0.099	NA	0.121	8.1e-09	NA	6.5e-06	NA	5.8e-07
7	GTEx	Liver	0.6010	0.0790	1.2e-07	0.516	NA	0.399	NA	0.519	1.1e-16	NA	3.1e-12	NA	7.6e-17
8	GTEx	Muscle Skeletal	0.0933	0.0392	6.6e-03	0.046	NA	0.026	NA	0.045	2.4e-05	NA	1.2e-03	NA	2.8e-05
9	GTEx	Nerve Tibial	0.2156	0.0496	3.3e-06	0.044	NA	0.104	NA	0.094	4.3e-04	NA	9.0e-08	NA	3.8e-07
10	GTEx	Skin Not Sun Exposed Suprapubic	0.2740	0.0660	3.6e-06	0.034	NA	0.150	NA	0.143	5.4e-03	NA	1.3e-08	NA	2.9e-08
11	GTEx	Skin Sun Exposed Lower leg	0.4080	0.0480	0.0e+00	0.390	NA	0.360	NA	0.380	3.4e-34	NA	4.4e-31	NA	3.7e-33
12	GTEx	Thyroid	0.2250	0.0540	1.6e-05	0.025	NA	0.078	NA	0.084	4.5e-03	NA	1.4e-06	NA	5.6e-07
13	YFS	Blood	0.0787	0.0195	1.6e-08	0.031	0.034	0.034	0.041	0.034	1.3e-10	3.1e-11	2.9e-11	2.7e-13	3.1e-11
14	TCGA	Bladder Urothelial Carcinoma	0.0470	0.0240	6.2e-03	0.013	0.022	0.006	NA	0.011	2.8e-02	5.6e-03	8.4e-02	NA	3.7e-02
15	TCGA	Breast Invasive Carcinoma	0.0469	0.0201	2.5e-04	0.005	0.013	0.006	NA	0.004	2.4e-02	9.2e-04	1.8e-02	NA	4.6e-02
16	TCGA	Colon Adenocarcinoma	0.1540	0.0590	5.6e-05	0.011	0.050	0.059	NA	0.028	6.9e-02	7.5e-04	2.6e-04	NA	8.7e-03
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.1197	0.0351	1.7e-10	0.082	0.086	0.074	NA	0.083	1.6e-09	6.0e-10	1.0e-08	NA	1.4e-09
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0903	0.0303	2.4e-05	0.076	0.034	0.052	NA	0.066	6.4e-09	9.6e-05	1.7e-06	NA	6.0e-08
19	TCGA	Liver Hepatocellular Carcinoma	0.2690	0.0640	2.0e-07	0.264	0.175	0.226	NA	0.249	9.1e-13	1.2e-08	5.7e-11	NA	4.7e-12
20	TCGA	Lung Adenocarcinoma	0.1289	0.0392	1.5e-09	0.029	0.086	0.079	NA	0.066	2.0e-04	2.7e-10	1.4e-09	NA	3.7e-08
21	TCGA	Prostate Adenocarcinoma	0.1134	0.0372	7.8e-08	0.039	0.087	0.063	NA	0.072	6.0e-05	2.4e-09	3.9e-07	NA	5.1e-08
22	TCGA	Thyroid Carcinoma	0.1080	0.0390	4.1e-06	0.066	0.073	0.056	NA	0.033	5.6e-07	1.2e-07	3.7e-06	NA	3.5e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Bipolar Disorder (2018)	1.3	2.0	6.2	-1.8	0.6	-1.4	-0.3	-1.3	1.9	1.2	0.8	-1.0	-1.0	-1.5	-0.1	-1.3	-1.4	-2.4	-0.5	-2.5	1.0	1.0	-2.3	-1.1	-1.9
Bipolar Disorder or Schizophrenia	3.3	8.0	20.5	-3.5	0.1	-1.5	-1.4	-3.6	3.8	1.2	2.3	-0.9	-3.0	-4.1	-2.1	-1.4	-4.0	-3.5	-2.7	-4.2	0.8	0.9	-4.2	-0.6	-4.5
Depressed Affect (Nagel 2018)	0.7	1.4	5.9	0.5	0.6	1.6	2.2	1.0	-2.4	-0.2	-0.5	1.7	1.4	1.5	1.8	0.7	1.1	0.9	0.7	0.5	-0.1	-0.1	0.3	0.7	1.4
Depression (Nagel 2018)	0.9	1.3	6.0	0.2	1.8	-0.0	0.4	0.9	-2.1	0.7	-2.5	-0.1	1.5	1.3	0.5	-0.5	0.1	0.1	1.8	0.9	0.9	0.9	0.0	-1.2	1.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.6	-0.8	-0.4	-0.8	-0.7	-1.1	1.6	1.5	0.7	-1.3	-0.4	-1.0	-1.3	-0.5	-0.8	0.8	-1.2	0.4	1.6	1.5	-0.1	-0.4	1.0
Neuroticism (Nagel 2018)	0.4	1.0	4.9	-0.5	0.6	2.2	1.6	0.4	-1.9	-1.0	0.0	2.1	0.4	0.6	0.8	0.1	0.6	-0.4	-0.2	-0.4	-1.2	-1.1	-0.4	1.1	-0.2
Schizophrenia (2018)	3.3	6.9	18.4	-3.1	-0.6	-0.8	-1.6	-3.6	3.3	0.6	2.3	-0.4	-3.0	-4.1	-2.7	-0.7	-4.0	-2.6	-3.0	-3.4	0.3	0.3	-3.6	0.1	-4.3
Schizophrenia vs Biploar Disorder	0.8	1.0	5.2	-0.1	-0.1	1.5	1.1	-0.4	0.6	-0.5	1.7	1.5	0.4	-0.4	0.1	2.3	0.2	1.7	-0.2	0.9	-0.5	-0.6	0.8	1.5	0.1
Worry (Nagel 2018)	0.6	1.3	4.7	-1.3	0.8	2.1	1.7	0.0	-0.3	-1.2	1.2	2.2	0.0	0.1	0.4	-0.3	0.9	-1.0	-0.8	-0.5	-1.6	-1.5	-0.3	1.2	-0.9
Alzheimer’s Disease (in mother)	1.4	1.6	5.5	-0.9	0.2	-1.6	-1.9	-0.5	-0.1	-1.4	-1.1	-1.0	-1.0	-0.8	-1.3	-0.9	-1.2	-2.3	0.3	-1.2	-1.4	-1.3	-1.6	-1.3	-2.0
Alzheimer’s Disease (in father)	0.5	0.6	1.6	-0.4	-1.0	0.2	-1.2	-0.2	1.0	1.3	0.5	0.4	-1.2	-0.6	-0.3	-0.6	-0.4	-0.3	-0.8	-0.8	1.1	1.1	-0.7	-0.2	-0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	2.7	-0.7	-0.0	-0.1	-1.0	-0.8	-0.2	-0.7	-0.4	0.2	-1.4	-1.1	-0.5	-0.2	-0.6	-1.7	-0.2	-1.3	-0.9	-0.9	-1.4	-0.3	-1.0
Crohns Disease (2017)	0.3	0.6	3.4	-0.3	0.6	0.3	0.2	-0.1	-0.1	-0.7	1.8	1.8	0.1	-0.1	0.4	-0.8	0.6	0.3	-0.2	-0.6	-0.8	-0.7	0.5	1.3	-0.3
Irritable Bowel Disease (IBD)	0.3	0.7	2.2	-1.2	1.1	-0.6	-0.5	-0.4	-0.2	-1.3	1.1	0.9	-0.8	-0.4	0.3	-0.9	0.4	0.1	-0.3	-1.1	-1.5	-1.4	0.2	1.0	-0.4
Ulcerative Colitis (UC)	0.6	1.1	2.6	-1.6	1.3	-1.5	-1.4	-0.9	0.0	-1.2	0.1	-1.1	-1.4	-0.9	-0.7	-0.9	-0.5	-0.5	-0.5	-1.5	-1.3	-1.3	-0.7	0.0	-0.6
Major Depression (MDD)	0.5	0.6	3.5	-0.8	0.3	-0.1	-0.5	-0.1	1.4	-0.3	0.7	-0.0	0.1	-0.4	-1.2	-1.9	-0.1	-0.9	0.8	-0.3	-0.5	-0.3	-0.0	-0.4	-1.4
Reaction Time	1.0	2.0	4.8	-1.4	0.7	0.9	1.3	-1.7	1.3	2.2	2.0	0.4	0.3	-1.6	-0.4	1.7	-0.7	1.9	-1.4	-1.4	2.0	2.0	0.3	1.9	0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.4	-0.8	-0.1	-0.8	-0.3	-1.4	0.7	1.8	-0.3	-2.1	-1.1	-1.3	-2.0	0.1	-1.7	0.9	-1.4	-0.2	2.0	2.0	-0.3	-0.6	0.8
Breast Cancer	0.5	1.1	6.8	0.8	1.2	1.1	0.4	1.2	-1.8	-0.1	-2.6	1.3	0.7	1.3	0.9	-0.6	0.7	-0.0	0.9	0.8	-0.0	-0.0	1.1	-0.3	1.2
Ovarian Cancer	0.8	1.1	3.3	1.8	-1.0	1.0	0.9	1.0	0.4	-1.0	-0.1	0.6	0.7	1.0	0.3	1.0	1.3	1.6	1.3	1.8	-0.8	-1.0	1.2	0.5	0.9
Prostate Cancer	1.3	1.8	6.4	0.2	-2.5	2.4	0.9	-1.1	1.2	-0.9	1.1	2.4	-1.8	-1.7	0.5	0.5	0.1	-0.6	-1.0	-1.2	-1.0	-1.2	-0.0	1.9	-0.7
Age at First Birth	0.5	0.7	2.5	-0.1	0.8	0.1	0.5	1.1	0.1	-0.7	-1.0	0.4	1.4	1.1	0.4	0.4	0.3	-1.2	1.6	0.7	-0.9	-0.8	0.1	-1.4	-0.9
Bipolar Disorder (2011)	1.3	1.2	6.3	-0.6	-0.7	-0.3	-0.6	0.2	1.3	2.5	0.6	0.3	-0.1	-0.1	1.0	-0.9	-0.6	-1.4	-0.1	-0.6	2.1	2.1	-0.8	-1.2	-1.3
Body Mass Index (BMI) (2010)	0.8	1.1	4.2	0.2	1.0	-1.3	-1.0	0.1	-1.9	-0.2	-1.2	-1.6	0.2	0.3	-0.9	-1.2	-0.5	-2.1	0.5	-1.1	-0.2	0.1	-0.9	-1.8	-0.4
Coronary Artery Disease (CAD)	0.7	0.9	4.9	2.2	-0.4	1.1	-0.2	1.5	-0.4	-1.0	-0.2	0.3	0.8	1.3	-0.2	-0.3	0.7	-0.5	1.2	0.9	-1.2	-0.9	1.2	-0.1	-0.8
Crohns Disease (2012)	0.4	0.6	3.2	-1.7	-0.1	-0.9	-0.5	-0.6	0.8	0.1	1.8	0.9	0.0	-0.6	0.6	-0.5	0.1	0.5	-0.4	-1.3	-0.0	-0.0	-0.2	1.2	-0.6
Mean Putamen Volume	0.6	0.7	3.1	0.5	-1.8	0.7	-0.9	0.6	-0.4	-0.1	-0.4	0.5	0.6	0.5	1.3	-0.4	1.1	1.2	0.7	0.5	0.0	-0.0	1.2	0.6	1.2
Fasting Glucose	1.5	1.8	5.1	0.5	1.8	0.1	0.8	2.2	-1.9	-1.2	-1.6	1.0	0.9	2.0	1.0	0.7	2.2	0.4	1.4	0.5	-1.2	-1.4	1.5	0.5	1.2
HbA1C	0.3	0.4	1.3	-0.1	-0.7	-0.2	-0.0	1.1	0.5	0.5	-0.2	0.3	0.7	1.1	0.5	-1.1	0.6	-0.3	0.2	0.5	0.6	0.6	0.5	-0.7	-0.3
HDL Cholesterol	0.4	0.7	4.8	-0.7	-0.2	0.6	1.4	-0.4	-0.5	-0.9	0.3	1.2	-1.0	-0.5	0.1	0.2	0.3	1.0	-0.9	-0.0	-0.8	-1.0	0.7	2.2	-0.2
LDL Cholesterol	0.5	0.7	1.8	1.3	0.6	1.0	-1.0	-0.6	-0.3	-0.7	1.2	1.2	-0.7	-0.6	-1.0	-1.1	-0.3	-0.2	-0.9	-0.5	-0.8	-0.8	0.4	1.3	-0.8
Lupus	0.6	0.9	4.5	1.2	-1.8	-1.2	0.3	-0.3	-1.0	-0.6	-2.1	-1.5	-0.5	-0.3	-0.1	0.6	-0.1	-0.8	0.2	-1.6	-0.5	-0.5	-0.6	-0.9	0.5
Neuroticism (2016)	0.7	1.0	3.8	-0.3	0.9	1.5	2.0	0.6	-1.4	-0.4	-0.5	1.8	0.4	0.5	1.1	-0.3	1.3	0.2	-0.4	1.0	-0.5	-0.6	1.2	1.4	0.8
Primary Biliary Cirrhosis	0.9	1.3	3.6	-1.5	-1.6	-1.4	-1.2	-1.4	1.9	0.7	0.6	-1.0	-0.7	-1.6	-0.7	-0.2	-1.2	-1.2	-0.4	-1.0	0.6	0.6	-1.1	-1.1	-0.9
Rheumatoid Arthritis	0.3	0.4	3.6	-0.5	1.9	0.1	-1.2	-0.3	0.3	-0.0	1.1	0.1	-0.4	-0.2	-0.2	0.7	-0.0	-0.0	-0.9	-0.7	-0.1	0.0	-0.6	0.5	-0.1
Schizophrenia (2014)	4.7	10.4	25.5	-4.3	-0.8	-1.0	-1.0	-4.8	4.4	1.8	4.0	-1.0	-3.2	-5.0	-3.4	-0.1	-5.0	-2.3	-3.3	-3.9	1.4	1.4	-4.0	0.1	-4.5
Triglycerides	0.4	0.7	2.2	0.6	-0.9	-0.9	-0.8	1.2	0.3	-0.8	-0.1	-0.5	-0.2	1.0	0.4	-1.0	0.8	-1.5	1.0	-0.0	-0.9	-0.7	-0.1	-1.5	-0.7
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.9	0.3	-1.7	-0.7	-1.0	1.0	-0.5	1.1	-1.0	0.0	1.9	1.1	1.9	-0.3	0.5	0.2	2.0	1.0	1.0	1.0	0.1	-1.4	0.8
Ulcerative Colitis	0.3	0.4	1.8	-1.0	1.3	-1.2	-0.6	-0.1	0.0	-1.0	-0.5	-0.5	-0.6	-0.2	0.1	-0.1	0.3	0.1	0.4	-0.8	-1.0	-0.9	0.0	0.2	-0.3
Blood Eosinophil Count	0.3	2.0	9.6	-0.5	1.3	1.2	2.7	-0.2	0.8	0.9	0.6	1.8	0.0	-0.4	-0.5	2.2	0.2	3.1	0.1	0.3	1.1	1.1	2.0	2.1	1.2
Blood Platelet Count	0.3	3.4	13.6	2.4	-1.0	0.8	1.2	3.6	-0.6	-0.5	-0.9	1.9	2.6	3.7	2.5	-0.5	2.5	0.4	2.1	2.6	-0.6	-0.5	1.7	-0.6	0.7
Blood Red Count	0.3	2.5	12.5	-0.5	3.5	-1.6	-3.2	-0.1	-1.0	1.4	-1.3	-2.2	0.6	0.2	0.9	-1.3	-0.2	-1.7	0.6	-1.0	1.5	1.6	-0.7	-2.4	1.3
Blood White Count	0.7	4.8	13.3	1.8	2.4	0.9	1.1	3.5	-1.6	0.7	-2.7	1.9	3.1	3.6	3.4	0.2	3.2	-0.1	2.7	1.9	0.7	0.8	2.0	-1.5	2.4
Heel T-Score	0.5	4.3	13.1	-1.5	-2.0	-3.1	-1.5	-1.4	2.7	3.2	0.7	-3.6	1.2	-1.3	0.3	-0.7	-1.7	-1.1	-0.2	-1.4	3.0	3.3	-2.1	-3.2	-0.0
BMI	0.2	1.2	5.6	-0.1	2.4	-0.2	0.2	-0.3	-1.2	1.6	-1.7	-0.6	0.2	-0.1	-0.6	1.4	-1.5	1.1	-0.2	0.3	1.8	1.8	-0.0	-0.7	1.1
Height	0.7	13.0	40.2	-3.0	-0.3	-2.1	-2.5	-6.3	2.4	2.0	1.8	-4.4	-4.7	-5.8	-6.0	1.1	-6.3	-0.2	-4.4	-3.5	2.4	2.3	-3.9	-0.7	-1.5
Waist Hip Ratio (WHR)	0.2	0.8	3.8	0.9	1.0	-1.2	-0.5	0.8	-0.7	0.4	-1.9	-0.7	1.2	1.1	0.4	0.1	0.0	-0.6	0.7	0.8	0.6	0.8	0.0	-1.8	0.6
Systolic Blood Pressure	0.2	1.0	3.5	1.9	1.0	1.3	1.8	0.6	-0.8	1.0	-0.7	0.7	1.7	1.0	1.2	0.2	0.4	1.1	0.2	0.7	0.9	0.8	0.7	0.3	0.7
Smoking Status	0.7	1.6	4.3	1.6	-0.5	-1.3	-1.0	1.4	-1.3	0.4	-2.1	-0.9	1.6	1.6	0.4	-0.3	0.5	0.8	1.5	2.1	0.8	0.8	1.1	-1.7	1.9
Allergy or Eczema	0.9	2.3	9.8	-3.1	0.1	1.0	0.7	-1.5	2.3	0.3	1.8	1.0	-3.0	-2.1	-0.6	0.9	-0.3	0.4	-2.1	-1.8	0.2	-0.0	-0.1	2.3	-0.5
Cardiovascular Disease	0.4	1.4	3.9	1.5	1.2	0.3	0.6	1.4	-1.7	0.5	-1.8	-0.1	1.7	2.0	0.3	0.7	0.8	1.6	1.2	1.0	0.8	0.7	1.0	-0.2	1.7
Hypothyroidism (self reported)	0.4	1.0	4.5	0.6	-1.5	1.2	2.0	0.0	-2.1	-0.9	-1.1	0.3	0.9	0.2	-0.1	1.2	-0.1	0.8	0.8	0.7	-0.8	-0.8	0.6	0.8	0.5
Respiratory disease	0.4	1.0	5.8	-1.1	0.9	-0.6	-0.3	-1.0	2.4	1.0	2.4	0.1	-0.2	-1.1	-0.2	0.3	-0.3	0.5	0.1	-1.1	0.9	0.8	0.1	0.7	-0.5
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.8	1.3	-0.1	-0.9	-0.5	1.0	-0.5	0.6	-1.8	-1.3	1.0	1.1	0.2	-1.5	-0.2	0.0	1.4	0.4	0.7	0.8	-0.3	-1.9	0.4
Lung FEV1/FVC ratio	0.8	4.0	16.7	1.2	-0.8	-0.1	-1.1	4.1	-1.6	-0.6	-2.1	0.4	2.3	4.1	2.5	-2.1	2.9	-1.5	2.5	2.2	-0.8	-0.5	1.1	-2.1	0.3
Lung FVC	0.7	3.6	8.4	-2.2	0.0	-2.2	-1.4	-2.4	1.7	1.5	1.8	-2.8	-0.8	-2.0	-1.4	-1.6	-2.5	-1.7	-2.0	-2.7	1.2	1.3	-2.9	-1.6	-1.3
Neuroticism	0.2	0.5	2.8	-0.7	0.7	1.7	1.2	0.2	-1.2	-0.0	0.3	1.4	0.4	0.6	0.3	0.0	0.3	-0.6	-1.1	0.1	-0.3	-0.2	-0.2	0.4	0.2
Chronotype (morning person)	0.7	1.6	6.2	1.2	-1.1	1.8	-0.4	-0.4	-1.5	-2.5	-0.3	0.8	-0.6	-0.5	-0.9	0.8	-0.1	-0.8	0.7	-0.7	-2.5	-2.5	0.6	1.4	-1.5
Hair Pigment	0.0	1.1	2.6	1.4	1.4	0.6	1.6	0.9	-1.5	-1.3	-1.1	0.8	0.3	1.0	-0.2	1.1	0.4	1.6	0.7	1.1	-1.1	-0.9	1.5	0.7	0.2
Tanning	0.1	1.5	8.8	-0.2	-0.5	-1.2	-1.8	-1.4	-0.5	-0.1	-0.7	-3.0	-0.9	-1.2	-1.9	-0.7	-1.8	-0.8	-0.1	-1.2	-0.1	-0.1	-1.7	-1.0	-0.7
Hand grip strength (left)	0.5	1.2	6.7	-0.3	-1.1	0.0	0.6	-1.6	0.6	-0.6	-1.0	-0.3	-2.2	-2.0	-1.0	2.6	-1.3	-0.3	-0.5	-0.7	-0.6	-0.8	-0.8	0.4	-0.4
Number of treatments/medications taken	1.4	2.5	12.2	0.9	0.3	1.0	3.5	0.9	-3.2	0.7	-1.5	-0.6	1.7	1.8	0.1	3.0	-0.2	1.6	0.9	1.7	0.9	0.9	1.1	0.0	1.7
Average weekly spirits intake	0.5	0.6	1.5	-0.5	0.6	0.5	-0.4	-0.8	0.3	0.8	-0.2	-0.5	-0.3	-0.9	-0.5	0.7	-1.2	-1.0	-0.2	-1.2	0.9	1.0	-1.2	-0.8	-0.5
Sensitivity / hurt feelings	0.1	0.2	1.2	0.5	-0.5	1.1	0.5	-0.3	-1.1	0.5	-0.1	-0.2	0.4	0.1	-0.3	0.2	-0.4	0.1	-0.2	0.3	0.4	0.5	0.1	-0.0	0.5
Frequency of depressed mood in last 2 weeks	0.8	1.1	6.0	0.7	0.6	-0.0	0.3	0.9	-2.3	0.5	-2.4	-0.0	1.2	1.3	0.7	-0.5	0.0	0.6	1.3	1.0	0.7	0.7	0.0	-1.0	1.1
Hearing difficulty/problems: Yes	0.2	0.4	1.7	-1.3	-0.0	-0.1	-0.4	0.5	-0.5	-0.1	0.5	-0.3	1.0	0.6	-1.0	-0.8	-0.5	0.4	-0.0	-0.2	-0.2	0.0	-0.3	-0.2	-1.3
Relative age of first facial hair	0.3	0.5	1.7	0.2	0.9	0.8	0.9	0.7	0.1	-0.7	-0.6	1.3	0.1	0.7	0.8	0.6	1.2	0.7	-0.1	0.4	-0.7	-0.8	0.5	0.6	0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	4.8	0.3	-0.5	-0.0	0.7	0.3	-2.2	-1.3	-0.6	0.1	0.2	0.4	-0.1	0.2	0.4	-0.4	0.2	0.0	-1.2	-1.2	0.1	0.4	-0.3
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.4	0.4	-0.3	-1.6	-0.9	-0.0	-1.2	1.3	-0.7	-1.8	0.7	0.6	-0.9	-0.4	-1.2	-0.4	-0.6	-0.7	1.3	1.5	-1.5	-1.6	0.1
Ever had hysterectomy (womb removed)	2.3	2.6	8.9	2.2	0.8	2.0	1.0	1.0	-1.5	0.9	0.2	0.9	2.8	1.5	0.1	0.1	0.9	3.0	1.3	2.5	1.1	1.0	2.5	1.5	2.1
Systolic blood pressure, automated reading	0.3	0.9	4.2	0.5	2.0	0.4	1.2	0.9	-0.7	1.1	-0.4	0.4	2.1	1.3	1.6	0.3	0.3	-0.5	0.3	0.1	0.8	0.9	-0.4	-1.0	-0.0
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	9.5	0.0	-1.2	-2.2	-2.0	-0.9	2.2	1.6	-0.0	-3.1	-1.1	-0.9	-1.8	-1.9	-1.9	-0.4	-0.1	-1.1	1.7	1.8	-1.5	-1.8	-1.0
Angina	0.4	0.5	2.2	-0.7	-0.5	0.1	-0.0	-0.7	-0.7	0.7	0.1	-0.5	0.3	-0.2	-0.9	0.3	-1.5	-0.8	-1.0	0.9	0.8	0.9	0.3	-0.5	-0.5
Medication for hormone replacement therapy	1.0	1.1	3.0	-1.6	0.8	-1.7	-1.2	-0.9	1.1	0.6	1.1	-0.8	-0.1	-0.8	-1.2	0.0	-1.0	-0.8	-0.7	-1.7	0.4	0.6	-1.7	-0.4	-1.2
Vitamin and mineral supplements	0.4	0.5	1.3	0.6	0.8	0.3	0.9	0.7	-0.1	0.8	-1.1	-0.0	0.8	0.8	0.1	0.2	0.2	0.4	1.0	0.6	1.0	1.1	0.6	-0.9	1.1
Supplements: Zinc	0.4	0.5	1.6	-1.0	-1.2	-0.4	-0.6	-0.6	0.6	0.3	-0.3	-1.3	-0.2	-0.5	-1.0	-0.6	-1.1	-0.1	-0.3	0.2	0.4	0.3	-0.8	-0.7	-0.5
Medication: Co-codamol	0.2	0.2	1.3	0.3	1.1	-0.2	0.9	0.6	-0.3	0.1	-0.8	0.1	0.3	0.6	0.5	0.6	0.6	0.4	-0.2	0.2	0.1	0.2	0.4	-0.1	0.4
Medication: Metformin	0.5	0.7	2.6	0.7	-0.1	-0.2	0.3	0.8	0.4	1.5	-0.2	-0.4	0.6	0.8	0.8	0.3	0.4	0.5	0.5	0.8	1.5	1.6	1.0	-1.0	1.2
Diabetes (father)	1.5	1.8	8.6	2.6	-0.7	0.8	0.5	1.9	0.0	-1.0	-1.2	0.1	1.5	1.4	1.2	0.2	2.2	1.1	2.9	0.9	-1.0	-0.9	1.5	0.5	0.8
Diabetes (mother)	1.2	1.5	4.0	-0.6	1.3	-0.5	-0.6	-1.0	1.2	2.0	0.6	-1.1	-0.8	-0.9	-0.3	-0.5	-1.4	-1.6	-1.8	-0.6	1.8	1.9	-1.6	-1.6	-0.7
Severe depression (siblings)	0.7	0.8	3.3	-0.8	-0.3	0.1	0.5	-0.7	0.6	1.8	1.1	-0.1	0.3	-0.4	-0.4	-0.5	-1.1	-0.4	-1.0	-0.1	1.6	1.6	-1.2	-0.5	-0.6
Pack years adult smoking proportion	1.6	2.5	6.5	1.4	0.3	1.3	2.4	1.3	-1.1	1.4	-0.8	0.9	1.6	1.6	2.2	1.6	1.6	2.1	0.9	1.7	1.6	1.4	2.1	1.0	2.5
Impedance of leg (right)	1.0	5.0	20.4	0.8	0.0	2.5	2.0	2.7	-0.9	-2.7	-0.2	2.6	1.5	2.3	2.4	-0.3	4.5	0.5	1.9	1.8	-2.8	-2.8	3.5	2.0	1.6
Leg fat-free mass (left)	1.1	5.9	26.7	-0.7	1.6	-1.5	-1.1	-3.5	0.0	2.6	-0.1	-3.4	-1.7	-2.9	-4.1	1.5	-5.2	0.7	-2.2	-1.3	3.0	3.0	-2.8	-1.4	-0.6
Trunk fat percentage	0.6	2.3	7.6	-0.1	1.4	-0.8	0.2	-0.3	-1.5	2.2	-1.8	-2.5	1.2	0.4	-1.7	1.3	-2.2	1.1	0.1	0.2	2.4	2.7	-0.4	-1.8	1.2
Hand grip strength (right)	1.0	2.7	9.3	-1.2	-1.3	-0.9	-0.3	-2.7	1.5	0.4	-0.1	-1.2	-3.0	-2.9	-1.5	1.7	-2.5	-1.3	-1.9	-1.9	0.3	0.2	-2.1	-0.4	-1.1
Townsend deprivation index at recruitment	1.2	1.6	7.3	1.3	0.3	0.4	-0.1	0.6	-0.4	0.4	-1.6	0.3	1.3	0.6	1.3	1.0	1.1	2.5	1.7	1.7	0.8	0.5	2.0	0.5	2.7
Current tobacco smoking	2.2	3.6	10.3	2.3	-0.0	0.5	0.8	2.5	-2.4	-0.0	-1.8	-0.1	2.8	2.8	1.8	-0.0	2.5	1.4	2.3	3.1	0.4	0.3	2.3	-0.6	3.2
Average weekly fortified wine intake	1.1	1.2	4.1	-0.9	-1.5	-1.7	-2.0	0.3	1.9	0.9	1.0	-1.3	-0.0	0.4	-1.2	-0.6	-1.0	-0.4	-0.6	0.5	0.9	1.1	-0.4	-1.7	-1.1
Maternal smoking around birth	1.3	1.9	5.8	2.4	-0.0	2.2	1.2	1.0	-1.9	-0.9	-2.4	1.5	1.0	0.8	1.4	0.0	1.2	0.4	1.5	1.7	-0.9	-0.9	1.8	0.5	0.9
Fed-up feelings	1.1	1.9	6.7	1.0	1.3	1.7	1.5	1.3	-2.6	-0.6	-0.8	1.9	1.5	1.7	1.3	0.2	1.3	1.9	0.3	1.6	-0.3	-0.4	1.4	1.1	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.6	15.3	1.5	1.4	0.3	0.9	1.2	-3.1	0.8	-3.9	-0.1	1.5	1.7	0.8	0.2	0.6	1.3	1.9	1.7	1.2	1.1	1.1	-1.1	2.6
Relative age voice broke	1.9	2.9	8.3	1.0	0.8	1.4	2.0	2.6	-1.6	-1.2	-2.1	2.9	1.0	2.3	2.6	-0.0	2.7	1.4	1.5	1.1	-1.3	-1.2	1.5	1.2	0.8
Taking other prescription medications	0.3	0.5	3.5	-0.1	-0.3	-0.5	1.9	0.0	-1.1	-0.1	0.0	-1.1	0.2	0.4	-1.3	1.4	-0.6	-0.2	-0.2	-0.3	-0.1	0.1	-0.6	-0.2	-0.2
Age when periods started (menarche)	0.7	1.6	5.1	2.0	-1.9	-1.7	-1.3	0.9	-1.3	-0.1	-2.2	-1.7	0.5	0.9	-0.4	-1.6	-0.5	-1.5	1.0	0.3	0.1	0.2	-0.4	-2.3	-0.5
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	7.4	0.6	-0.8	1.4	0.6	-0.1	0.4	0.5	1.1	0.5	0.3	-0.1	-0.0	1.5	0.7	2.7	0.1	0.3	0.5	0.5	1.7	2.0	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	6.3	-0.8	0.2	-0.6	-1.0	-2.0	2.5	1.5	0.9	-0.4	0.1	-2.0	-1.5	0.3	-1.9	-0.1	-0.9	-1.2	1.3	1.4	-0.8	-0.5	-0.5
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.5	1.0	0.8	-1.6	-1.0	0.5	1.1	0.9	0.9	-1.9	0.4	0.4	0.1	-1.5	-0.1	-1.5	0.3	-0.0	0.8	1.0	-1.0	-1.7	-0.3
Qualifications: CSEs or equivalent	0.3	0.4	3.0	0.7	1.7	-0.3	0.2	-0.2	0.5	0.1	0.3	-0.5	0.8	-0.3	-0.1	-0.6	-0.5	-1.0	0.2	-0.6	0.1	0.1	-1.2	-0.6	-0.6
Serious illness, injury or assault to yourself	0.9	1.2	3.1	0.7	-0.6	-1.1	-0.0	-1.3	-1.1	1.2	-0.9	-1.5	-1.3	-1.1	-0.8	0.4	-1.7	-0.5	-0.2	-1.6	1.2	1.1	-1.8	-0.7	0.3
High blood pressure	0.4	1.3	6.1	1.8	0.8	-0.1	0.7	1.3	-2.5	0.1	-2.0	-0.7	1.7	2.0	0.2	0.1	0.5	0.8	1.0	0.5	0.3	0.3	0.5	-0.7	1.0
Hayfever, allergic rhinitis or eczema	1.1	2.4	9.3	-2.8	-0.1	0.0	0.6	-2.0	2.0	-0.2	1.4	-0.7	-3.1	-2.5	-1.6	0.6	-1.1	-0.1	-1.6	-2.2	-0.4	-0.5	-1.1	1.7	-1.2
Multivitamins +/- minerals	0.8	1.1	3.4	-1.9	-0.5	-0.4	-0.4	-1.4	0.7	-0.3	1.7	-0.2	-1.1	-1.5	-0.7	0.7	-0.9	-0.9	-1.1	-1.2	-0.6	-0.7	-1.2	0.9	-1.5
Stomach or abdominal pain in last month	0.5	0.6	3.4	0.4	1.8	1.0	-1.0	0.2	0.4	-0.3	-0.6	-0.2	-1.2	-0.2	-1.7	-0.9	-0.6	-0.3	-0.5	0.2	-0.2	-0.1	0.4	0.4	-1.4
Supplements: Glucosamine	2.2	2.9	9.9	-1.1	-2.0	-1.6	-1.2	-1.0	-0.2	0.1	0.6	-2.8	-1.4	-0.8	-2.5	-0.8	-2.4	-3.1	-1.3	-1.2	-0.1	0.3	-2.6	-2.1	-2.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.5	0.2	-0.1	0.3	-0.4	-0.3	-0.8	-1.9	0.7	-0.5	-1.0	-0.2	-0.9	-0.9	0.5	0.2	-0.3	-0.6	-1.8	-1.8	0.7	1.4	-0.5
Medication: Atenolol	2.1	2.7	13.2	0.3	-0.3	0.4	0.8	1.5	-3.6	0.3	-2.3	-0.7	2.3	2.4	1.0	2.0	0.5	1.3	1.5	2.4	0.7	0.7	1.5	-0.9	2.4
Medication: Levothyroxine sodium	0.4	0.6	4.4	0.2	-2.1	0.3	0.5	0.0	-0.9	-1.0	-0.8	-0.1	0.2	0.1	-1.0	0.8	-1.0	-0.5	0.1	-0.4	-1.0	-0.9	-0.6	-0.1	-1.3
Sitting height	0.7	4.7	24.2	-0.3	-0.2	-0.0	-1.4	-3.1	0.9	1.9	0.5	-2.8	-1.7	-2.9	-3.9	-0.6	-4.9	-0.8	-2.7	-0.4	2.2	2.2	-2.6	-1.3	-1.6
Chronic bronchitis/emphysema (father)	1.4	1.6	7.9	0.0	0.9	2.0	2.8	-0.4	-1.0	-1.0	0.5	1.3	-0.8	-0.3	0.7	2.2	0.8	1.4	-0.9	0.2	-0.9	-1.1	0.9	2.5	0.7
High blood pressure (mother)	0.5	0.8	4.0	-0.3	-0.3	-1.2	-0.8	-0.6	-0.1	-0.2	0.3	-2.0	-0.8	-0.2	-1.4	-0.8	-0.6	-1.0	-1.1	-0.8	-0.2	-0.0	-1.5	-1.1	-0.1
Body mass index (BMI)	0.4	1.5	4.4	-0.0	2.0	-1.2	-0.5	-0.5	-1.4	1.5	-1.6	-1.8	0.2	-0.0	-1.3	1.1	-2.1	0.7	-0.2	0.1	1.7	1.9	-0.6	-1.5	0.7
Impedance of leg (left)	0.9	4.6	18.8	0.8	0.0	2.7	2.3	2.9	-0.4	-1.9	-0.5	2.9	1.7	2.4	2.8	-0.0	4.3	0.4	1.8	1.9	-2.1	-2.0	3.4	1.6	1.5
Leg predicted mass (left)	1.1	6.1	27.5	-0.7	1.6	-1.5	-1.2	-3.6	0.1	2.5	-0.1	-3.5	-1.7	-3.0	-4.2	1.4	-5.2	0.6	-2.3	-1.4	2.9	3.0	-2.9	-1.4	-0.7
Trunk fat mass	0.8	3.4	11.4	-0.4	1.5	-1.5	-0.3	-1.2	-1.3	2.5	-1.7	-3.4	0.5	-0.4	-2.7	1.6	-3.4	0.9	-0.5	-0.2	2.8	3.1	-1.2	-2.2	0.9
Waist circumference	0.5	1.8	4.4	0.4	1.7	-1.2	-0.8	-0.5	-2.0	1.4	-1.9	-2.1	0.5	0.2	-1.6	0.8	-2.1	0.6	-0.1	0.2	1.8	2.0	-0.5	-1.8	1.0
Number of incorrect matches in round	0.3	0.5	1.3	-0.9	-1.0	0.3	-0.9	0.5	-1.1	-0.6	-0.8	0.2	0.5	0.6	-0.7	0.2	-0.5	-0.9	-0.1	0.1	-0.7	-0.4	0.1	-0.8	-1.1
Past tobacco smoking	0.5	0.9	4.3	-1.0	-0.3	1.3	1.1	-0.3	-0.9	-1.4	1.4	0.2	-0.7	-0.3	-0.3	0.6	0.7	0.1	-0.9	-0.6	-1.5	-1.6	0.2	2.1	-0.1
Alcohol usually taken with meals	1.2	1.9	5.8	-0.8	-1.3	-2.3	-1.1	-1.3	0.4	1.2	0.2	-2.4	-0.8	-1.0	-0.9	-0.7	-1.7	-1.7	-1.2	-1.6	1.0	1.0	-2.4	-1.8	-0.8
Nervous feelings	0.5	0.8	2.9	-0.7	0.8	1.7	1.3	0.3	-0.0	-0.9	0.8	1.7	0.4	0.3	0.3	-1.1	1.1	0.7	-0.3	0.5	-1.2	-1.2	0.7	1.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	3.2	-0.6	1.8	0.9	0.2	-0.6	-0.8	-0.1	-0.9	-0.1	-0.5	-0.5	-0.9	-0.8	-1.0	-0.2	-0.1	-0.2	-0.1	-0.2	-0.7	0.1	-0.4
Hearing difficulty/problems with background noise	0.4	0.6	3.4	-1.8	-0.8	0.7	-0.3	0.1	0.0	-0.2	1.1	0.4	-0.9	0.1	-1.3	-0.8	-0.4	-0.3	-1.0	-0.3	-0.5	-0.3	-0.0	0.4	-1.6
Hair/balding pattern: Pattern 2	0.9	1.2	2.9	1.5	1.4	0.6	1.3	0.9	-1.5	-0.2	-1.6	0.5	1.3	1.3	1.1	1.0	0.8	0.7	0.5	1.5	0.1	0.0	1.2	0.0	1.7
Had menopause	0.5	0.6	2.6	-0.0	0.3	-0.0	-0.0	1.1	-0.7	1.0	0.2	-0.6	1.6	1.3	0.9	-0.9	0.7	-0.3	0.3	0.4	0.9	1.0	-0.2	-0.8	0.5
Had other major operations	1.0	1.2	6.3	-0.4	0.3	1.1	-0.8	-0.1	1.1	-1.6	1.2	1.1	-1.0	-0.4	-1.0	-1.2	-0.5	-1.0	-0.6	-0.4	-1.7	-1.6	-0.7	0.9	-2.5
Forced vital capacity (FVC)	1.8	6.9	17.3	-3.2	0.0	-1.8	-1.7	-4.2	3.3	2.1	2.4	-2.8	-2.6	-3.9	-3.2	0.1	-3.9	-0.8	-3.5	-2.9	2.0	1.9	-3.3	-0.7	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	4.7	-0.8	0.0	0.3	0.1	-1.5	2.2	0.6	0.8	-0.2	-0.4	-1.6	-1.4	0.8	-0.9	0.7	-0.6	-0.4	0.6	0.6	0.2	0.4	0.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.0	-0.9	-0.3	-0.4	0.0	-0.6	-0.3	-0.3	-0.8	0.5	-1.2	-0.9	-0.4	-0.5	-0.1	-0.5	-0.6	-1.4	-0.3	-0.3	-0.1	0.4	-0.3
Qualifications: None of the above	0.7	1.5	15.0	0.9	1.7	0.7	0.7	1.2	-3.9	-0.6	-1.2	0.6	1.4	1.6	1.4	0.3	0.9	0.7	-0.0	0.4	-0.5	-0.4	1.2	0.7	0.7
Financial difficulties in last 2 years	1.0	1.4	6.4	2.5	0.3	0.0	-0.2	1.2	-1.9	0.2	-2.0	-0.9	1.8	1.5	0.1	-0.2	0.3	0.2	1.8	1.2	0.4	0.4	0.4	-1.3	1.0
Mouth/teeth dental problems	1.9	3.0	9.8	-3.1	-0.1	-3.1	-3.0	-1.0	1.2	-0.1	0.5	-2.2	-1.8	-1.3	-1.6	-2.6	-1.6	-2.1	-0.8	-0.9	-0.1	-0.1	-1.2	-1.4	-1.8
Heart attack	0.8	1.0	3.1	-0.1	1.1	-0.9	0.3	0.3	-0.3	1.1	-0.4	-1.8	1.0	0.8	-1.0	1.1	-0.9	1.4	0.8	1.4	1.5	1.6	0.8	-0.6	0.5
Allergy	1.3	3.1	9.3	3.0	-0.9	0.6	-0.7	2.7	-1.3	-0.0	-1.6	1.5	3.0	2.9	2.0	-0.9	1.7	-0.1	1.9	2.8	0.2	0.3	1.6	-1.5	1.1
Pain all over the body in last month	0.4	0.4	3.4	0.3	1.9	0.6	0.3	0.2	-1.1	-0.0	-1.1	0.6	-0.5	0.0	-0.8	-1.1	-0.1	-0.1	-0.2	-0.7	0.0	0.2	0.4	0.3	-0.2
Diabetes (self-reported)	0.8	1.2	5.0	0.5	-0.1	-1.0	-1.5	1.1	-0.2	1.2	-1.5	-1.4	1.1	1.3	0.1	-1.0	-0.5	-0.1	1.1	0.6	1.4	1.6	-0.0	-2.2	0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.4	-1.6	-0.9	-0.7	0.2	-1.3	0.4	-0.9	0.2	-1.0	-1.8	-1.6	-0.7	0.2	-1.0	-1.1	-1.1	-1.5	-1.0	-1.0	-1.3	0.1	-0.8
Medication: Ramipril	0.2	0.3	1.8	1.3	-0.9	0.3	0.5	0.7	-0.6	0.2	-0.2	0.0	0.9	1.1	-0.2	-0.2	-0.0	0.7	-0.0	0.3	0.3	0.4	0.3	-0.2	0.1
Medication: Simvastatin	0.8	1.2	3.9	0.3	0.6	-1.4	0.1	-0.1	-1.4	1.5	-1.7	-2.0	0.9	0.5	-0.8	0.8	-1.2	0.6	-0.8	0.2	1.7	1.8	-0.5	-1.0	1.0
Fluid intelligence score	0.9	2.0	5.1	-1.1	-0.9	-1.6	-0.9	-1.4	1.1	1.7	1.0	-1.6	-2.0	-1.2	-2.2	-1.1	-1.9	-0.3	-2.2	-0.4	1.7	1.8	-0.9	-0.9	-0.3
Illnesses of siblings	1.5	2.2	11.0	-1.8	-0.4	0.4	0.2	-1.9	0.0	-1.3	0.7	-0.4	-3.3	-2.2	-1.8	0.9	-0.8	0.9	-2.1	-1.8	-1.2	-1.3	-0.4	2.4	-0.3
Neuroticism score	0.4	0.8	4.7	-0.8	1.1	2.2	1.3	-0.0	-1.3	-0.0	0.4	1.7	0.6	0.3	0.4	0.3	0.5	0.5	-0.8	0.4	-0.2	-0.1	0.6	1.1	0.8
Weight	0.8	4.1	17.0	-0.5	1.8	-1.3	-0.6	-2.3	-0.7	2.4	-1.2	-3.2	-0.9	-1.6	-3.3	1.8	-4.1	1.0	-1.5	-0.4	2.8	3.0	-1.7	-1.7	0.5
Impedance of arm (right)	0.3	1.6	6.4	0.9	-0.1	1.2	1.2	1.7	-1.0	-1.0	-0.3	0.7	2.1	1.7	1.4	-0.4	2.5	0.6	1.1	0.7	-1.1	-1.0	1.5	0.7	1.3
Arm fat percentage (right)	0.5	2.0	6.2	0.1	1.8	-1.6	-0.6	0.2	-2.0	1.4	-2.1	-2.5	1.4	0.9	-1.2	0.9	-1.7	0.5	0.3	0.1	1.7	2.0	-0.7	-2.1	1.1
Trunk fat-free mass	1.0	5.6	23.7	-0.8	1.0	-1.6	-1.4	-3.8	1.1	1.9	0.5	-3.1	-2.5	-3.3	-4.3	1.4	-4.9	0.3	-2.5	-1.1	2.3	2.2	-2.5	-1.1	-1.0
Hip circumference	0.5	2.1	7.5	-0.5	1.7	-0.5	-0.0	-1.4	-0.6	2.0	-0.7	-2.0	-0.4	-0.8	-2.1	1.4	-2.7	1.3	-1.0	-0.2	2.3	2.4	-0.8	-1.1	0.9
Time employed in main current job	1.8	2.0	5.1	1.8	-2.0	-0.2	0.4	1.8	1.9	0.5	-0.2	0.7	1.2	1.7	2.2	-0.6	2.3	1.7	1.2	1.9	0.7	0.5	1.9	-0.2	1.5
Alcohol intake versus 10 years previously	0.5	0.7	2.3	0.9	1.5	-0.8	0.5	1.1	-1.0	-0.0	-1.0	-0.6	1.1	1.3	-0.5	0.8	0.3	0.7	0.9	0.9	0.3	0.3	0.7	-0.7	0.8
Father’s age at death	0.9	1.3	5.4	-1.0	-0.6	-0.5	-1.3	0.6	-1.0	-1.7	0.8	-0.7	0.0	0.4	-0.2	-1.3	0.3	-1.4	0.5	-1.3	-1.9	-1.7	-0.9	0.1	-2.3
Worrier / anxious feelings	1.1	2.1	9.9	-0.9	0.4	3.1	2.1	0.4	-0.1	-0.8	0.9	2.7	-0.3	0.4	1.0	1.9	1.7	1.1	-0.6	1.0	-1.0	-1.1	1.7	2.1	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	3.4	0.4	1.0	-0.7	0.5	-0.1	-1.9	0.2	-0.4	-0.9	1.2	0.5	-0.9	0.3	-0.7	1.1	-0.0	0.0	0.5	0.5	-0.4	0.1	0.7
Falls in the last year	0.7	1.0	5.6	0.1	-0.7	0.2	-0.6	0.4	0.3	2.3	-0.3	-0.7	0.9	0.6	-0.3	0.1	-0.9	0.5	0.0	0.7	2.4	2.4	-0.2	-1.0	0.3
Hair/balding pattern: Pattern 3	2.9	4.3	13.4	-2.0	0.1	-3.7	-2.7	-0.5	0.4	0.7	-1.3	-3.2	-1.7	-0.8	-1.6	-1.7	-2.0	-3.3	-0.1	-2.3	0.8	1.0	-3.2	-3.6	-1.7
Number of live births	0.7	0.9	5.1	0.5	0.4	0.4	0.9	-0.5	-0.8	1.0	-1.2	0.3	0.7	-0.4	0.2	1.1	-0.5	2.3	0.3	1.0	1.2	1.0	1.4	1.1	1.3
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	6.4	-2.5	0.2	-1.7	-1.9	-2.1	1.9	1.2	1.0	-1.9	-1.6	-2.1	-1.7	-0.9	-2.3	-0.9	-2.2	-1.9	1.1	1.0	-2.5	-1.0	-1.4
Pulse rate	0.7	1.1	6.8	-0.6	-0.4	-1.1	-2.6	0.5	1.4	-0.0	-0.4	-1.4	0.3	0.2	-0.4	-2.0	-0.1	-1.6	0.3	-0.5	-0.1	0.1	-0.5	-1.5	-1.4
Happiness	0.7	0.8	4.5	-0.7	0.1	0.5	-0.4	1.6	0.8	-0.7	-0.4	1.4	0.4	1.6	0.3	-0.6	1.1	0.8	0.5	2.1	-0.5	-0.5	1.2	-0.2	0.1
Noisy workplace	0.6	0.7	3.4	-1.1	0.1	-0.3	-1.3	-0.8	1.6	-0.1	1.3	-0.2	-0.3	-1.1	-0.3	-0.4	-0.7	-0.8	0.1	-1.4	-0.2	-0.1	-0.4	0.1	-1.8
Qualifications: A levels/AS levels or equivalent	0.3	0.6	7.3	0.0	-0.9	0.4	-0.2	-0.0	2.7	0.3	1.6	0.4	-0.1	-0.3	-0.4	0.4	0.2	0.8	0.5	1.1	0.3	0.3	0.5	0.3	-0.3
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.5	1.4	-0.4	1.5	1.8	1.3	-0.6	-1.0	-0.2	1.3	0.6	1.3	0.8	0.4	2.1	1.4	1.4	1.9	-0.8	-1.0	1.5	1.1	1.6
Mouth/teeth dental problems: Dentures	0.3	0.4	1.4	0.2	-1.2	0.4	-0.4	-0.2	0.3	1.2	-0.4	0.4	1.0	-0.0	0.2	1.1	-0.4	0.1	0.3	-0.3	1.2	1.2	-0.2	-0.8	0.5
Asthma	0.6	1.1	4.4	-0.3	0.8	-0.4	0.6	-1.6	0.6	-0.6	2.1	-0.9	-1.1	-1.4	-2.0	0.2	-0.8	0.6	-0.8	-1.6	-0.6	-0.7	-0.7	1.4	-0.7
Medication: Ibuprofen (e.g. Nurofen)	2.3	3.0	9.7	1.8	0.5	1.6	2.4	1.2	-2.1	0.2	-1.3	1.3	1.6	1.7	1.3	1.2	1.2	2.5	1.4	3.1	0.5	0.3	2.3	0.6	3.1
Medication: Cholesterol lowering	0.4	0.6	3.6	-0.6	0.6	-0.5	1.3	-0.2	-1.3	0.0	-0.5	-1.2	0.9	0.4	-0.6	1.9	-0.3	0.6	-0.3	0.2	0.3	0.3	0.5	0.1	0.9
Depression (self-reported)	2.2	2.7	8.3	-0.9	0.7	-0.5	-0.5	-1.8	1.4	1.8	1.9	-1.9	0.2	-1.5	-2.9	-1.3	-2.5	-1.2	-1.0	-1.9	1.5	1.6	-2.4	-0.7	-2.2
Medication: Lansoprazole	3.2	3.6	10.0	1.3	-0.4	1.6	0.8	2.7	-1.5	0.6	-2.7	1.6	2.1	2.5	1.7	1.0	2.2	2.3	2.1	2.9	0.7	0.7	3.2	0.5	2.2
Prospective memory result	0.4	0.5	2.4	-0.4	-0.4	0.8	0.2	0.2	-0.7	-0.9	-0.9	0.5	1.3	0.1	0.1	0.4	-0.1	1.1	1.6	0.3	-0.7	-0.7	0.8	0.6	-0.4
Lung cancer (father)	0.8	0.9	3.0	-0.8	-1.7	0.7	-0.3	-1.4	0.9	0.1	1.7	0.4	-1.4	-1.6	-0.4	-0.9	-0.9	-1.4	-0.9	-0.5	-0.0	-0.1	-0.2	0.4	-1.1
Illnesses of mother	1.4	1.7	6.3	1.1	-0.4	1.9	1.4	0.4	-1.0	-0.7	0.3	2.3	0.8	0.2	1.5	0.3	1.5	2.0	1.1	0.5	-0.6	-0.9	2.1	2.5	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.3	6.2	-2.2	0.4	-1.5	-1.8	-2.2	1.8	-0.0	1.5	-2.0	-2.0	-2.3	-2.3	-1.3	-2.3	-1.9	-2.5	-2.0	-0.1	-0.1	-2.3	-0.7	-2.3
Pulse wave Arterial Stiffness index	0.6	0.7	2.0	1.2	1.0	0.8	0.9	0.4	0.3	1.3	-1.4	-0.6	0.7	0.5	0.2	0.4	-0.1	-0.1	0.7	0.8	1.4	1.4	0.5	-1.0	0.5
Impedance of arm (left)	0.1	0.6	2.6	-0.3	-0.9	0.7	0.9	0.9	0.2	-0.2	0.5	0.4	1.4	0.8	0.9	-0.7	1.6	0.4	0.6	0.1	-0.3	-0.2	1.1	0.5	0.7
Arm fat mass (right)	0.6	2.7	9.0	-0.2	1.9	-1.4	-0.6	-1.1	-1.4	1.9	-1.7	-2.8	0.1	-0.5	-2.4	1.5	-3.0	0.9	-0.8	-0.1	2.2	2.5	-1.0	-1.8	0.8
Trunk predicted mass	1.0	5.7	24.1	-0.8	1.0	-1.5	-1.4	-3.8	1.1	2.0	0.5	-3.1	-2.5	-3.3	-4.3	1.5	-4.9	0.3	-2.5	-1.1	2.4	2.3	-2.6	-1.1	-1.0
Standing height	0.7	7.3	26.1	-1.6	-0.2	-0.6	-0.5	-4.5	1.7	2.5	1.0	-3.7	-2.7	-3.9	-4.9	1.7	-5.1	0.9	-3.4	-1.2	3.0	2.9	-2.4	-0.6	-0.4
Length of working week for main job	0.8	0.9	4.4	0.8	-0.9	-0.3	-0.9	-0.9	0.8	-0.8	2.1	-0.7	-1.3	-0.7	-1.0	-0.4	0.7	0.2	-1.6	-0.7	-0.7	-0.9	-0.2	1.1	0.2
Exposure to tobacco smoke at home	0.7	0.7	2.4	-0.6	0.6	0.3	0.6	-1.4	-0.8	0.0	0.2	0.0	-1.2	-1.6	-0.2	1.5	-0.8	-0.9	-1.5	-1.4	-0.0	0.0	-0.8	0.5	0.1
Breastfed as a baby	6.2	7.7	16.9	-2.1	-3.2	-3.8	-3.2	-1.8	3.8	0.0	3.1	-4.1	-2.4	-1.9	-3.6	-2.5	-2.6	-3.5	-2.0	-2.2	-0.0	0.1	-3.0	-2.2	-3.9
Tense / ‘highly strung’	0.3	0.4	4.0	0.2	0.5	2.0	1.6	0.0	-0.5	0.6	-0.4	0.8	0.1	0.1	0.4	-0.4	0.2	-0.1	0.2	0.3	0.3	0.3	-0.0	0.2	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.2	-1.0	1.0	-0.6	-0.7	-0.1	-0.8	-0.2	-0.3	-0.4	0.1	-0.2	-1.0	-1.1	-1.2	-1.0	-0.6	-0.6	-0.2	-0.1	-1.0	-0.1	-1.5
Hair/balding pattern: Pattern 4	0.7	1.6	6.4	-0.2	-0.8	2.2	0.9	0.1	1.1	0.1	1.5	2.5	0.2	0.1	1.2	0.8	1.0	1.9	0.1	1.4	-0.0	-0.1	2.2	2.2	0.2
Birth weight of first child	0.3	0.6	2.9	-0.7	-1.4	1.3	0.6	-0.5	0.0	0.2	-0.8	0.1	-0.5	-0.5	0.3	1.1	0.5	1.2	0.0	0.4	0.3	0.1	0.8	0.9	1.7
Peak expiratory flow (PEF)	0.2	0.4	3.0	-0.5	-0.9	0.1	-0.8	0.5	1.7	0.2	-0.4	0.3	-0.4	0.3	0.2	-0.3	0.5	0.4	0.8	1.1	0.3	0.3	0.8	-0.5	0.0
Pulse wave reflection index	0.6	0.8	4.0	0.3	1.1	-0.3	2.0	-0.9	0.1	1.5	-0.0	0.1	-0.0	-0.6	0.8	0.8	-0.7	-0.1	-0.8	-0.5	1.5	1.3	-1.0	-0.2	0.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.8	-0.2	0.6	-0.7	-0.7	0.7	-0.1	-0.3	0.2	-0.8	0.9	0.9	-0.6	-0.6	0.3	-0.0	0.3	-0.3	-0.2	-0.1	-0.5	-0.5	-0.1
Loud music exposure frequency	0.7	0.8	2.5	-1.6	1.0	0.5	0.7	-0.8	-1.2	-1.1	0.0	0.8	-0.9	-0.8	0.4	1.2	-0.2	-0.4	-0.9	-1.0	-1.1	-1.2	-0.4	1.0	-0.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.8	0.2	-1.6	-1.5	-1.0	-0.1	1.1	0.2	-0.4	-1.2	0.3	0.0	-0.9	-0.4	-0.8	-1.1	0.5	0.1	0.2	0.2	-1.3	-1.7	-0.4
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	7.2	2.5	0.9	2.7	2.5	0.8	-1.2	-0.3	-0.4	1.5	1.1	1.1	1.1	2.3	1.2	2.1	1.1	1.3	-0.2	-0.3	1.5	1.6	1.2
Blood clot in the leg (DVT)	0.3	0.4	1.8	-0.3	0.3	-0.5	0.1	-1.2	-0.1	1.0	-0.4	-0.9	-0.3	-1.1	-0.1	0.3	-0.8	0.4	0.2	-1.3	0.9	0.8	-0.7	-0.2	0.3
Medication: Paracetamol	0.7	1.2	4.3	1.3	0.7	1.0	2.1	0.3	-1.3	0.1	-0.1	0.0	1.5	0.8	0.6	1.5	0.3	2.0	0.4	1.3	0.3	0.2	1.4	0.8	1.5
Headache pain in last month	0.4	0.6	2.3	-0.1	-0.2	-1.1	0.7	-0.9	-0.6	-0.8	-0.1	-1.5	-1.4	-0.7	-0.5	1.1	-0.3	-0.3	-1.3	-0.8	-0.6	-0.6	-0.9	-0.1	0.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	5.5	-0.5	0.1	0.3	-1.5	-0.7	2.3	0.5	1.2	0.6	-1.6	-1.5	-0.3	-1.5	-0.5	-0.3	-0.8	-0.7	0.2	0.3	-0.8	0.6	-1.2
Glaucoma (self-reported)	0.9	1.1	4.7	-0.3	-0.5	-0.5	-0.9	0.6	-0.5	-2.1	-0.6	-0.6	-0.6	0.3	0.2	-1.8	1.2	-1.0	0.9	-0.8	-2.2	-2.0	-0.0	-0.5	-0.1
Gout (self-reported)	1.3	1.8	3.7	-1.2	1.5	-1.6	-1.7	-0.3	-1.6	-1.6	-1.2	-1.0	-0.3	-0.3	-0.8	-1.5	-0.8	-1.8	0.2	-1.9	-1.5	-1.4	-1.9	-1.1	-1.8
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	5.3	0.4	-2.3	1.0	2.3	-0.1	-1.0	-0.9	-0.3	0.5	0.2	0.0	-0.3	1.7	-0.3	0.6	0.1	0.4	-0.9	-0.9	0.2	0.8	-0.1
Medication: Amlodipine	2.3	3.2	7.3	2.6	-0.7	1.5	0.4	2.7	-1.1	-1.3	-1.8	1.1	2.3	2.7	2.2	0.3	2.6	0.4	2.7	2.4	-1.2	-1.2	2.1	-0.6	1.3
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.9	-1.8	1.2	0.6	0.8	-1.5	0.8	-0.0	1.0	-0.0	-1.4	-1.7	-1.0	-0.7	-1.2	-0.3	-0.6	-2.0	0.0	-0.1	-1.0	0.8	-1.5
Birth weight	0.6	1.3	5.4	-0.5	-1.3	-1.7	-1.0	-1.5	1.2	0.6	1.3	-1.6	-1.4	-1.3	-2.3	0.0	-1.4	-0.1	-1.1	-1.1	0.7	0.8	-0.7	0.0	-0.1
Chronic bronchitis/emphysema (mother)	0.8	0.9	6.9	0.3	0.7	0.4	-0.2	-1.0	-0.0	-0.6	-1.3	-0.8	-2.6	-1.2	-2.1	0.4	-1.1	0.1	-0.6	0.0	-0.3	-0.4	-0.4	0.2	-0.1
High blood pressure (siblings)	1.2	1.7	7.3	0.3	0.6	-1.8	-1.4	0.3	0.5	1.0	0.6	-1.2	2.1	0.7	0.2	-2.7	-0.5	-2.2	0.3	-0.5	0.7	0.8	-1.8	-2.3	-1.6
Forced vital capacity (FVC), Best measure	1.6	6.0	14.4	-3.0	0.9	-1.6	-1.2	-3.8	2.7	0.7	2.4	-2.7	-2.6	-3.7	-3.4	-0.4	-3.5	-1.5	-3.4	-2.9	0.7	0.6	-2.9	-0.3	-2.2
Body fat percentage	0.5	2.0	4.8	0.2	1.9	-0.9	0.2	0.4	-2.0	1.6	-2.2	-2.2	1.5	1.1	-1.0	1.2	-1.6	0.8	0.6	0.5	1.8	2.2	-0.2	-2.0	1.2
Leg fat percentage (right)	0.6	2.0	7.4	0.6	2.0	-0.4	0.5	1.7	-2.7	0.2	-2.5	-1.2	1.8	2.2	0.3	1.2	0.2	0.6	1.5	1.5	0.4	0.7	0.8	-1.6	1.7
Arm fat-free mass (right)	1.0	5.1	22.4	-0.9	1.0	-1.2	-0.8	-3.4	0.8	2.4	0.0	-3.0	-2.1	-3.0	-3.8	1.9	-4.7	0.9	-2.1	-0.7	2.8	2.8	-2.0	-1.1	-0.5
Exposure to tobacco smoke outside home	1.0	1.3	4.0	1.1	-0.7	-0.2	1.0	0.2	-1.6	2.0	-1.0	0.8	1.4	0.8	1.4	0.8	-0.3	1.2	0.3	0.8	2.0	2.0	0.2	-0.6	1.6
Comparative body size at age 10	1.3	3.5	11.7	-1.6	-0.3	-0.2	-0.2	-3.4	0.5	1.9	1.1	-0.7	-2.1	-3.4	-1.6	-0.1	-3.0	-0.3	-3.1	-2.8	1.7	1.6	-2.3	1.1	-0.7
Number of full brothers	0.2	0.3	1.6	0.8	0.1	0.1	1.2	0.0	0.2	-0.3	0.6	0.9	0.2	0.0	0.6	-1.3	0.3	-0.1	0.1	-0.0	-0.5	-0.6	-0.0	0.3	-0.9
Worry too long after embarrassment	0.3	0.5	2.6	-1.6	0.2	0.7	0.5	-1.0	0.3	0.4	0.7	0.3	-0.5	-0.7	-0.5	0.7	-0.8	-0.7	-1.6	-0.6	0.1	0.2	-0.9	0.2	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	5.1	6.7	17.4	-2.9	0.4	-2.1	-2.2	-2.9	1.1	-0.5	1.7	-2.3	-2.6	-3.3	-2.9	-2.0	-2.9	-4.1	-2.3	-4.2	-0.8	-0.6	-4.0	-0.5	-3.9
Wheeze or whistling in the chest in last year	0.3	0.5	2.7	0.5	1.6	-0.1	0.5	0.1	-1.6	-0.6	-1.0	-0.1	0.8	0.2	-0.5	-0.7	0.1	-0.2	1.0	-0.8	-0.5	-0.5	-0.1	0.1	0.0
Number of children fathered	0.2	0.3	1.4	0.0	0.5	0.2	-0.6	0.3	0.6	-0.2	0.3	0.4	0.0	0.1	-0.4	-0.7	0.2	-1.1	0.6	-0.9	-0.3	-0.3	0.1	-0.2	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.1	-1.1	1.0	0.5	-0.3	-0.5	1.3	-1.0	-0.1	-0.1	-1.1	-0.9	-1.8	-0.4	-0.4	-1.2	0.5	-0.1	-0.9	-0.9	-0.4	-0.2	-0.9
Age at first live birth	1.4	2.5	7.1	0.9	0.2	1.5	0.5	2.7	-0.4	-1.6	-0.8	2.4	0.9	2.3	2.0	-0.5	2.1	-0.5	2.1	2.5	-1.7	-1.7	1.7	-0.5	-0.2
Pulse wave peak to peak time	0.5	0.6	2.2	-1.2	-0.8	-0.7	-0.8	-0.6	0.0	-1.2	1.5	0.5	-0.8	-0.6	-0.3	-0.3	-0.1	0.4	-0.8	-0.7	-1.2	-1.2	-0.6	1.0	-0.5
Health satisfaction	0.9	1.2	3.2	0.6	0.7	1.1	0.1	1.4	-0.8	-1.3	-0.3	1.2	0.7	1.3	0.2	-0.1	1.6	1.5	1.1	1.3	-1.2	-1.1	1.8	1.3	1.0
Shortness of breath walking on level ground	0.8	1.0	7.2	0.2	2.7	0.0	1.0	1.2	-0.6	-1.2	0.5	-0.0	1.5	1.4	-0.1	-0.1	1.1	0.5	1.3	0.6	-1.0	-0.9	0.4	0.2	0.1
Qualifications: College or University degree	0.4	1.1	11.3	-0.9	-0.5	0.3	-0.2	-0.9	3.4	0.4	2.2	0.1	-1.5	-1.0	-1.2	-0.4	-0.5	0.2	-0.4	0.8	0.2	0.3	0.0	-0.2	-0.6
Eye problems/disorders: None of the above	0.2	0.2	0.8	-0.1	0.3	0.0	0.1	-0.2	-0.8	-0.6	0.7	0.4	0.3	0.2	-0.2	0.3	-0.5	-0.7	-0.6	0.4	-0.8	-0.6	-0.5	0.2	-0.9
Mouth/teeth dental problems: Loose teeth	0.7	0.8	4.6	0.2	2.1	0.3	0.4	1.3	-1.0	-1.0	-0.6	0.8	1.4	1.3	0.6	-0.2	1.3	0.0	0.8	0.1	-0.8	-0.7	-0.1	0.1	0.6
Emphysema/chronic bronchitis	0.5	0.6	3.2	0.4	1.8	-0.5	0.8	-0.2	-1.4	-1.2	-0.9	-0.1	1.0	-0.1	0.3	0.2	0.2	0.0	0.8	-0.4	-1.0	-1.1	0.2	0.1	0.0
Medication for pain relief, constipation, heartburn	1.6	2.8	7.5	-1.4	-0.5	0.0	-2.1	-1.5	2.7	-0.7	2.0	1.2	-2.5	-2.3	-0.3	-1.3	-0.2	-2.2	-1.5	-2.5	-1.2	-1.2	-1.7	0.7	-2.5
Neck or shoulder pain in last month	0.3	0.5	2.0	-0.4	-0.8	0.9	1.2	-0.1	0.3	0.6	0.7	-0.4	0.2	0.0	-0.3	1.3	0.1	1.4	-0.6	0.1	0.6	0.5	0.4	1.1	0.5
Medication: Blood pressure	1.0	1.7	8.9	1.2	-0.4	-0.8	0.9	1.5	-3.0	-0.2	-2.3	-1.3	1.9	2.5	0.3	0.5	0.4	0.1	1.1	1.0	0.1	0.2	0.2	-1.7	1.3
Angina (self-reported)	0.4	0.5	2.5	-1.0	-0.3	0.1	0.2	-0.8	-0.8	0.7	-0.1	-0.7	0.0	-0.4	-0.9	0.7	-1.6	-0.7	-1.2	0.6	0.9	0.9	0.1	-0.4	-0.3
Migraine (self-reported)	1.6	1.9	5.7	-1.7	-0.7	-0.3	1.6	-2.0	1.1	-0.1	1.8	0.2	-2.1	-2.0	-1.0	1.6	-1.4	0.2	-1.9	-2.4	-0.3	-0.3	-1.1	1.4	-0.8
Medication: Ibuprofen	2.5	3.0	9.2	1.7	-0.5	2.5	2.7	0.7	-1.5	0.4	-0.7	1.6	1.1	1.2	1.3	2.0	1.1	2.4	1.1	2.9	0.6	0.3	2.4	1.1	3.0
Medication: Allopurinol	1.4	1.9	5.4	-1.4	0.7	-2.2	-2.0	-0.8	-0.7	-0.7	-1.0	-1.4	-0.3	-0.8	-0.8	-1.8	-1.3	-2.0	-0.2	-2.2	-0.8	-0.6	-2.3	-1.5	-1.7
Medication: Omeprazole	0.5	0.6	3.8	-1.0	1.9	0.5	1.1	-0.7	-0.1	-0.0	0.4	-0.0	-1.0	-0.5	-1.4	0.7	-0.5	1.0	-0.0	0.1	0.2	0.1	0.7	1.0	0.3
Medication: Seretide 50 evohaler	0.2	0.2	1.2	-0.1	0.5	0.3	0.8	0.4	-1.1	-0.3	0.3	0.6	0.4	0.6	-0.4	-0.5	0.3	0.0	0.0	0.2	-0.2	-0.2	0.3	0.5	-0.2
Mean time to correctly identify matches	1.2	2.2	7.0	-2.1	-0.0	0.2	0.6	-2.3	0.9	1.9	2.2	-0.3	-0.8	-2.1	-1.1	1.0	-1.3	1.1	-2.6	-1.9	1.7	1.7	-0.4	1.8	0.0
Heart disease (mother)	2.1	2.6	8.1	0.5	1.2	-0.2	-0.5	2.0	1.0	2.8	-0.5	0.8	2.8	2.1	1.7	-0.4	0.3	-0.1	1.4	2.0	2.7	2.8	0.5	-2.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	7.9	-1.2	-2.8	-1.2	-1.7	-0.4	1.7	-1.8	1.3	-0.1	-1.8	-0.9	-0.7	-0.1	-0.1	-0.8	0.2	-1.3	-1.8	-1.9	-0.6	0.5	-1.8
Whole body fat mass	0.6	2.7	8.0	-0.2	2.1	-1.2	-0.1	-0.8	-1.6	2.1	-1.8	-2.8	0.5	-0.1	-2.1	1.6	-2.8	1.0	-0.3	0.1	2.4	2.7	-0.8	-1.9	0.9
Leg fat mass (right)	0.5	1.8	5.2	-0.1	2.3	-0.7	0.2	-0.2	-2.2	1.1	-2.1	-2.1	0.6	0.5	-1.4	1.8	-1.8	0.9	0.1	0.5	1.5	1.8	-0.2	-1.5	1.2
Arm predicted mass (right)	0.9	4.4	19.6	-0.7	1.1	-1.1	-0.7	-3.1	0.5	2.5	-0.3	-2.7	-1.8	-2.6	-3.4	1.6	-4.4	0.9	-1.8	-0.3	2.9	2.8	-1.8	-1.1	-0.2
Pulse rate, automated reading	0.6	1.8	6.8	-0.8	-0.5	-1.6	-2.0	-0.8	0.9	0.1	0.0	-1.6	-1.4	-0.9	-1.0	-0.8	-1.2	-2.2	-1.3	-2.4	-0.2	-0.0	-2.6	-1.3	-1.4
Alcohol intake frequency.	0.5	1.3	4.6	1.4	1.0	0.9	1.0	1.0	-0.5	-0.2	0.3	0.4	1.3	1.2	0.4	0.9	1.5	2.1	0.6	1.3	0.0	-0.1	1.9	1.3	1.7
Comparative height size at age 10	1.2	6.5	25.3	-2.3	-1.5	-0.5	0.1	-4.7	-0.0	1.5	0.4	-2.5	-2.8	-4.2	-4.2	1.9	-5.0	0.4	-3.3	-2.4	1.7	1.6	-2.8	0.4	-1.0
Number of full sisters	1.5	1.9	5.1	2.1	-0.7	0.8	1.1	0.4	1.8	2.2	0.8	0.4	1.2	0.5	0.6	1.5	0.4	2.2	-0.2	1.5	2.2	2.1	1.4	0.2	1.6
Suffer from ‘nerves’	0.5	0.7	3.3	-1.4	1.0	1.8	1.0	-0.7	0.7	0.3	1.3	1.4	0.4	-0.6	0.2	-0.7	-0.0	0.1	-0.9	-0.3	0.1	-0.0	-0.0	1.2	-0.5
Overall health rating	1.1	2.3	7.4	1.6	0.2	1.1	2.0	1.1	-2.5	0.8	-0.7	0.2	1.9	1.8	0.3	1.9	1.0	2.4	1.2	1.7	1.0	1.2	1.8	0.6	2.7
Chest pain or discomfort	0.4	0.6	2.6	0.6	0.2	1.0	0.3	-0.9	0.6	0.1	1.4	0.1	-0.2	-0.8	-1.6	-0.4	-0.9	0.2	-0.5	-0.3	-0.0	-0.1	-0.4	1.2	-1.2
Had major operations	1.8	2.1	7.5	-0.9	-0.8	-2.2	-0.8	-1.6	-1.0	0.4	-0.3	-2.7	-1.2	-1.3	-1.6	-0.1	-2.5	-2.0	-1.2	-1.4	0.2	0.4	-2.1	-1.8	-0.7
Age at last live birth	0.8	1.2	5.7	1.9	-0.3	0.0	-0.6	1.6	0.1	0.1	-0.8	0.7	1.1	1.6	0.8	-0.9	1.1	0.0	1.8	2.4	0.2	0.0	1.4	-0.8	0.7
Family relationship satisfaction	1.4	1.7	6.4	-1.4	0.2	-2.4	-2.5	-0.1	1.6	-0.5	1.0	-1.1	-0.6	0.0	-1.8	-2.1	-0.9	-1.6	-1.1	-0.2	-0.4	-0.2	-0.9	-1.5	-1.8
Leg pain on walking	0.9	1.1	4.4	-0.1	-0.2	1.7	-0.2	1.0	-0.8	-2.1	-0.9	1.2	-0.0	0.6	-0.3	-0.1	1.1	-0.2	0.8	0.1	-2.1	-2.0	1.0	1.1	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.6	0.3	1.1	1.7	1.2	-0.3	-0.2	-0.9	0.0	1.7	-0.2	-0.9	-0.4	1.1	0.0	0.2	0.3	-0.5	-0.9	-1.1	0.2	1.9	-0.8
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.2	1.4	-0.0	0.8	1.5	1.5	-1.0	-0.8	-1.0	0.2	1.2	1.8	1.4	0.8	1.7	0.9	1.6	1.2	-0.7	-0.7	1.2	-0.1	1.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	5.3	-1.8	0.5	1.2	0.9	0.0	1.5	1.1	0.6	2.3	-0.5	-0.3	1.6	1.2	0.5	0.5	-0.6	0.3	0.8	0.9	1.2	0.6	0.4
Medication: Aspirin	2.5	3.3	11.4	1.6	0.1	-0.7	0.7	2.6	-2.2	0.5	-2.0	-2.3	2.9	3.4	0.3	0.3	0.8	0.5	2.3	3.0	0.9	1.1	1.4	-2.4	1.5
Supplements: Vitamin C	0.7	0.9	3.8	1.4	-1.2	0.1	0.0	0.4	-0.2	-0.8	0.0	-0.6	-0.5	0.3	-0.6	-0.7	0.9	2.0	0.6	1.7	-0.5	-0.7	1.6	1.0	1.1
Knee pain experienced in last month	1.2	1.9	8.0	1.5	0.7	1.6	1.9	0.8	-0.8	-0.2	-0.6	0.6	0.4	1.0	0.3	2.8	1.5	2.3	0.9	1.8	-0.1	-0.1	1.8	0.9	2.4
Hypertension (Self-reported)	0.5	1.4	9.8	1.7	0.5	-0.1	0.9	1.3	-3.1	-0.1	-2.1	-0.6	1.9	2.2	0.2	-0.2	0.4	0.5	0.8	0.7	0.0	0.0	0.3	-0.7	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.8	-0.6	0.1	1.5	1.5	0.2	-1.5	0.2	-1.3	1.7	0.3	0.3	0.2	1.4	0.4	1.5	0.3	0.7	0.3	0.2	1.6	1.5	1.1
Illnesses of father: Heart disease	0.7	0.9	3.0	0.9	1.0	1.2	-0.4	1.3	0.1	-0.6	-0.7	0.9	1.1	1.4	0.7	0.5	1.0	0.8	1.3	1.7	-0.6	-0.7	1.4	0.0	0.8
Illnesses of siblings: Diabetes	0.8	1.0	4.8	0.4	2.2	0.7	0.7	0.9	0.3	0.1	-0.1	1.4	1.9	0.9	1.6	0.5	1.2	-0.4	1.1	1.2	0.0	-0.1	0.7	-0.5	0.4
Smoking status: Previous	0.4	0.5	2.2	0.5	0.0	-1.5	-0.9	-0.3	0.9	0.4	-0.8	-0.1	-0.3	-0.5	0.1	-0.2	-0.9	-0.8	0.3	-1.0	0.3	0.3	-1.1	-1.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.6	13.9	-2.7	0.5	-1.0	-1.2	-3.0	1.8	0.2	2.0	-1.7	-2.1	-2.9	-3.7	-0.1	-2.9	-0.3	-2.6	-1.8	0.3	0.4	-1.6	-0.1	-1.4
Whole body fat-free mass	1.0	6.0	26.5	-0.8	1.5	-1.5	-1.2	-3.8	0.7	2.3	0.2	-3.2	-2.3	-3.2	-4.3	1.6	-5.1	0.5	-2.4	-1.2	2.7	2.7	-2.7	-1.2	-0.9
Leg fat-free mass (right)	1.2	6.4	28.7	-0.8	1.6	-1.3	-1.0	-3.6	0.5	3.0	-0.1	-3.3	-1.7	-3.0	-4.1	1.6	-5.4	0.9	-2.3	-1.2	3.4	3.4	-2.8	-1.4	-0.6
Arm fat percentage (left)	0.5	2.1	6.8	-0.4	1.5	-1.8	-0.7	-0.0	-1.5	1.8	-1.8	-2.6	1.2	0.6	-1.3	0.8	-2.0	0.5	0.1	-0.0	2.0	2.3	-0.8	-2.3	0.9
Average weekly red wine intake	0.5	0.7	4.4	0.2	-1.2	-0.0	-0.9	-0.4	1.0	-0.1	0.7	-0.0	-0.3	-0.6	0.5	-2.1	0.1	-1.8	-0.0	-0.9	-0.4	-0.4	-0.8	-0.2	-1.6
Handedness (chirality/laterality): Left-handed	0.7	0.8	5.1	-0.0	2.3	-0.2	0.7	-0.4	0.2	1.3	-0.4	-0.6	0.1	-0.4	-1.5	-0.2	-1.5	-0.2	-0.3	0.2	1.4	1.6	0.2	-0.4	-0.4
Mood swings	0.4	0.8	2.8	0.5	0.8	1.3	1.0	0.6	-1.7	0.3	-0.4	1.5	0.7	0.8	1.0	0.3	0.8	0.8	0.2	0.6	0.4	0.4	0.8	0.5	1.5
Loneliness, isolation	1.1	1.5	3.7	1.0	1.1	1.1	1.7	1.4	-1.8	0.4	-0.9	0.5	1.7	1.9	0.9	0.5	1.0	1.0	1.1	1.8	0.4	0.5	1.2	-0.4	1.9
Long-standing illness, disability or infirmity	1.0	1.5	4.0	1.4	-0.7	1.4	2.0	1.8	-1.2	-0.2	-1.1	0.8	1.3	1.9	0.3	1.4	1.4	1.4	1.6	1.2	0.1	0.2	1.5	0.1	1.1
Ever had bowel cancer screening	1.8	2.1	7.2	-0.1	-1.4	-2.0	-2.6	-0.5	1.1	1.2	0.9	-2.7	0.3	-0.1	-1.5	-0.5	-1.7	-1.3	-0.3	-1.0	1.1	1.5	-1.8	-2.4	-0.9
Diabetes diagnosed by doctor	0.7	1.1	4.8	0.3	-0.4	-1.2	-1.4	0.7	-0.2	1.2	-1.6	-1.6	0.8	0.8	-0.0	-1.5	-0.6	-0.3	1.0	0.3	1.3	1.6	-0.1	-2.2	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.9	-0.2	0.3	-0.6	-1.4	0.1	-0.3	0.2	-1.0	-0.7	0.2	0.3	0.2	-0.7	-0.1	-0.0	-0.2	0.3	0.4	0.4	-0.7	-0.8	0.4
Friendships satisfaction	0.6	0.8	2.6	-1.2	-0.3	-0.8	-1.2	-0.2	1.0	-1.3	0.7	0.1	-1.2	-0.4	-1.5	-1.6	-0.2	-0.2	-0.8	-0.3	-1.1	-1.0	0.0	0.2	-1.0
Qualifications: nursing, teaching	0.6	0.9	6.8	-0.6	-2.6	0.8	-0.7	-0.4	-0.3	-0.8	0.1	0.5	-1.7	-0.5	-0.9	0.3	-0.6	-0.2	-1.3	-0.6	-0.8	-0.8	-0.7	1.0	-1.2
Commuting to job workplace: Walk	1.0	1.1	4.6	-0.9	0.1	0.1	-1.5	-0.4	2.1	-0.3	1.8	0.5	-1.0	-0.7	-1.2	-0.9	-0.8	-1.1	-0.5	-0.2	-0.6	-0.4	-0.8	-0.3	-2.1
Eye problems/disorders: Cataract	0.9	1.0	3.6	-0.0	-1.6	0.2	0.7	-0.0	0.9	1.7	-0.4	0.2	0.3	0.1	0.6	1.5	-0.1	1.6	0.5	0.5	1.9	1.7	0.6	-0.3	1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	5.3	1.3	0.4	1.2	2.3	-1.0	0.3	-0.1	1.4	0.6	-0.6	-0.8	0.5	0.9	0.5	1.9	-0.1	-0.5	-0.2	-0.3	0.5	2.0	0.9
Medication for cholesterol	0.9	1.4	4.9	-1.4	0.4	0.8	0.7	-1.9	1.0	-0.5	1.3	0.5	-2.2	-2.2	-0.2	0.6	-0.7	-0.9	-1.8	-1.5	-0.6	-0.7	-0.7	1.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	-0.7	1.3	-0.2	-0.4	1.0	0.2	1.1	-0.8	-0.5	0.4	0.8	0.0	-0.8	0.5	0.5	1.1	0.9	1.3	1.4	0.9	-0.7	0.8
Back pain experienced in last month	0.4	0.5	2.0	0.2	0.3	0.3	0.6	0.7	-0.8	-0.4	-1.0	0.5	1.1	0.8	0.7	0.9	0.8	1.0	0.9	0.9	-0.2	-0.3	0.6	0.0	1.4
Mineral and other dietary supplements	0.8	1.1	2.9	1.4	1.1	0.9	1.0	0.8	-1.1	-0.3	-1.1	0.8	0.8	0.7	0.8	1.3	1.3	1.1	1.6	0.9	-0.2	-0.4	1.4	0.6	1.7
Breast cancer (self-reported)	0.5	0.7	3.3	0.3	-1.8	1.1	1.0	1.0	-0.6	-0.8	-0.7	1.0	0.4	1.0	0.6	0.3	0.8	-0.1	0.5	0.8	-0.9	-1.0	0.6	0.4	-0.1
Asthma (self-reported)	0.7	1.3	5.9	-0.5	0.8	-0.4	0.6	-1.6	1.0	-0.1	2.4	-1.2	-1.1	-1.4	-2.2	0.5	-1.0	0.5	-1.0	-1.8	-0.2	-0.2	-0.8	1.2	-0.9
Osteoporosis (self-reported)	1.1	1.3	2.9	-1.7	0.2	0.4	-1.1	-0.9	-0.7	-1.3	1.6	1.3	-1.1	-1.1	-0.2	0.5	-0.2	-0.9	-1.7	-1.5	-1.5	-1.5	-0.5	1.7	-1.5
Osteoarthritis (self-reported)	2.6	3.4	13.2	0.8	0.3	0.4	2.1	1.8	-3.0	0.3	-2.3	-1.3	2.2	2.6	1.0	2.6	1.5	1.4	1.3	2.4	0.6	0.8	1.3	-1.3	3.6
Medication: Aspirin	2.1	2.8	8.7	1.4	0.5	-0.9	0.5	2.3	-1.8	0.5	-2.3	-2.5	2.5	2.9	0.2	0.7	0.3	0.3	2.2	2.7	0.9	1.1	0.9	-2.5	1.1
Medication: Gliclazide	0.9	1.0	5.4	0.3	-0.6	-1.1	-0.5	1.0	-0.8	0.9	-1.9	-1.3	1.0	1.2	0.1	-0.4	-0.3	-0.4	1.0	0.8	1.0	1.2	-0.1	-2.3	0.4
Illnesses of father: None of the above (group 1)	1.9	2.4	4.9	-2.0	-1.9	-1.4	0.2	-2.0	0.7	1.9	1.0	-0.8	-1.4	-1.9	-0.6	-0.6	-2.2	-1.1	-2.2	-1.7	1.8	1.8	-2.1	-0.8	-1.0
Smoking status: Current	2.4	3.8	12.2	2.2	0.0	0.5	0.8	2.5	-2.4	0.1	-2.0	-0.2	2.9	2.8	1.7	0.2	2.4	1.6	2.2	3.3	0.7	0.5	2.5	-0.6	3.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	8.1	-1.9	-0.7	-1.1	-1.1	-0.3	0.3	0.1	0.5	-0.7	-0.6	-0.3	-0.1	-1.2	-0.9	-2.9	-1.4	-1.8	-0.1	0.0	-1.9	-1.2	-2.3
Whole body water mass	1.1	6.1	27.2	-0.6	1.3	-1.6	-1.4	-3.8	0.7	2.4	0.1	-3.4	-2.2	-3.2	-4.3	1.5	-5.2	0.5	-2.4	-1.2	2.8	2.7	-2.8	-1.3	-0.8
Leg predicted mass (right)	1.2	6.4	29.0	-0.8	1.5	-1.4	-1.0	-3.6	0.4	3.0	-0.1	-3.3	-1.7	-3.0	-4.1	1.5	-5.4	0.8	-2.3	-1.2	3.4	3.4	-2.8	-1.5	-0.6
Arm fat mass (left)	0.7	2.9	9.9	-0.6	1.8	-1.6	-0.8	-1.2	-1.0	2.2	-1.5	-2.8	0.1	-0.6	-2.3	1.3	-3.2	0.9	-0.9	-0.2	2.6	2.8	-1.1	-1.9	0.7
Number of self-reported non-cancer illnesses	0.4	0.8	2.5	-0.4	0.1	-0.4	1.5	0.1	-0.8	1.0	-1.0	-1.6	0.9	0.6	-0.9	0.4	-0.2	0.6	1.0	-0.2	1.1	1.3	0.2	-1.0	1.3
Average weekly champagne plus white wine intake	0.4	0.6	3.2	0.5	-1.8	-0.1	-0.9	-0.4	-0.1	-0.6	0.7	0.6	-0.3	-0.4	-1.0	0.4	-1.1	-0.3	-1.2	-0.3	-0.6	-0.5	-0.8	0.3	-1.4
Miserableness	0.6	1.1	4.9	-0.1	0.4	0.2	2.2	0.5	-1.7	0.6	-0.2	0.9	1.2	0.9	1.3	1.3	0.7	1.7	-0.0	0.3	0.7	0.7	0.2	0.9	1.5
Guilty feelings	0.5	0.7	2.5	-1.3	-0.1	1.0	-0.7	-0.0	-0.3	-1.5	0.9	1.3	-0.3	0.2	-0.6	0.1	0.2	0.2	-0.9	-0.2	-1.6	-1.4	0.3	1.0	-0.9
Wears glasses or contact lenses	0.8	0.9	3.6	-1.7	0.6	-1.0	-0.8	-0.2	0.4	0.1	0.5	-0.2	-0.1	-0.3	-0.8	-1.3	-1.3	-1.4	-0.5	-1.2	-0.1	-0.1	-1.4	-0.9	-1.9
Ever taken oral contraceptive pill	0.2	0.2	1.1	0.2	1.0	-0.7	-0.6	-0.2	0.1	-0.0	0.4	0.2	0.1	-0.1	0.4	0.2	0.3	0.2	0.5	0.3	0.1	0.1	0.3	-0.1	1.0
Hearing aid user	0.7	0.8	2.6	0.5	-0.6	-0.7	0.3	0.5	0.7	1.5	-0.1	-0.9	1.2	0.8	0.3	0.5	-0.0	1.1	1.0	1.0	1.5	1.6	0.6	-1.1	1.0
Mother’s age at death	0.6	0.7	3.3	-0.8	1.0	-1.0	-1.0	-0.1	0.8	0.1	-0.0	-0.7	0.1	-0.2	-0.6	-1.0	-1.2	-1.8	-0.2	-0.1	0.2	0.2	-1.1	-1.4	-1.5
Financial situation satisfaction	0.3	0.3	2.2	0.1	-0.3	-0.5	-0.5	-0.1	-0.1	-0.3	-0.0	-1.3	0.5	0.1	-1.5	-1.0	-0.3	0.9	0.1	0.5	-0.1	0.0	0.3	-0.1	0.2
Tinnitus: Yes, now most or all of the time	1.0	1.2	11.6	-3.4	1.2	0.1	0.3	-1.1	0.7	0.6	1.3	0.3	-0.6	-1.2	-0.6	0.1	-1.0	-1.1	-1.2	-1.1	0.4	0.5	-1.1	-0.0	-1.0
Commuting to job workplace: Public transport	0.6	0.8	2.6	-1.4	0.1	-1.0	-0.4	-1.0	0.7	0.7	1.6	-0.1	0.5	-1.1	-0.4	-0.7	-1.1	-0.9	-0.4	-0.9	0.5	0.5	-1.6	-0.5	-0.6
Eye problems/disorders: Glaucoma	1.0	1.2	4.9	0.4	-0.6	-0.2	-1.0	1.4	-0.2	-1.5	-0.1	0.4	0.4	1.1	1.3	-2.2	2.2	-0.4	1.2	-0.1	-1.7	-1.5	0.4	-0.1	0.5
Medication: Blood pressure	1.0	1.8	6.5	1.7	0.1	0.3	0.6	2.2	-1.8	0.0	-1.6	0.4	2.3	2.5	0.9	-0.6	1.2	1.2	1.6	2.2	0.1	0.1	1.6	-0.5	0.5
Pain type(s) experienced in last month: Hip pain	0.8	1.1	3.7	1.6	-0.4	1.6	1.5	0.9	-1.9	-0.6	-0.5	0.5	1.3	1.2	0.7	-0.5	0.5	0.5	1.7	1.3	-0.5	-0.6	0.6	0.4	-0.0
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.7	-1.6	-0.3	-0.8	-0.5	-1.1	1.2	0.1	1.5	-0.1	-0.6	-1.2	-0.1	-1.3	-1.0	-0.6	-1.6	-1.3	-0.1	-0.1	-1.2	0.3	-1.5
High cholesterol (Self-reported)	0.6	1.1	4.2	0.2	-0.5	-1.8	-0.6	0.3	-0.5	1.3	-0.7	-2.1	1.5	0.9	-0.9	0.3	-0.7	0.5	0.1	0.6	1.5	1.6	-0.1	-1.3	0.9
Medication: Bendroflumethiazide	1.4	2.1	6.5	1.8	-0.3	-2.3	-0.2	2.1	-1.4	0.6	-1.5	-1.1	2.4	2.6	1.5	-0.9	1.0	0.1	1.5	0.9	0.7	0.9	0.3	-2.2	0.7
Medication: Paracetamol	1.7	2.6	10.7	1.5	0.7	1.8	3.3	0.7	-1.3	0.6	-0.3	0.8	1.8	1.2	1.5	2.5	0.6	2.8	0.8	1.9	0.8	0.7	2.1	1.2	2.0
Medication: Lisinopril	1.6	2.1	7.4	1.4	-0.5	1.1	2.7	1.4	-0.6	1.2	-0.2	0.7	1.1	1.5	1.8	2.3	1.5	1.9	1.6	1.1	1.2	1.0	1.8	0.5	1.9
Medication: Atorvastatin	0.6	0.7	3.4	-0.4	-0.5	-0.3	0.4	0.2	1.1	-1.2	1.0	-0.5	0.1	0.3	-0.0	1.8	0.5	0.8	1.3	0.2	-1.0	-1.0	1.3	0.3	-0.3
Illnesses of father: High blood pressure	0.3	0.4	2.6	1.0	1.6	1.1	-0.3	-0.2	-0.3	-0.1	-1.0	-0.0	-0.3	-0.2	-0.8	0.1	-0.1	0.4	-0.3	0.4	-0.1	-0.1	0.5	0.3	0.6
Alcohol drinker status: Never	1.4	1.6	5.6	0.8	0.9	2.3	1.7	0.3	-0.3	-0.8	0.8	2.2	-0.1	0.0	1.8	0.7	1.8	1.3	0.3	0.8	-0.9	-1.2	1.3	2.4	1.1
Ever smoked	0.9	1.5	6.1	0.5	0.6	-1.5	-1.1	-0.3	1.9	2.1	-0.7	-0.8	0.6	-0.1	-0.1	-0.9	-1.3	0.1	0.6	1.0	2.3	2.3	-0.4	-2.5	0.2
Basal metabolic rate	1.0	5.8	25.9	-0.7	1.5	-1.5	-1.3	-3.5	0.4	2.4	-0.1	-3.4	-2.0	-2.9	-4.3	1.5	-5.1	0.6	-2.3	-1.1	2.8	2.8	-2.6	-1.4	-0.7
Leg fat percentage (left)	0.6	2.1	7.5	0.5	2.0	-0.4	0.5	1.7	-2.4	0.8	-2.7	-1.1	1.9	2.2	0.5	1.3	-0.0	0.5	1.3	1.4	0.9	1.2	0.6	-2.0	1.6
Arm fat-free mass (left)	0.8	4.0	17.5	-0.1	1.6	-0.9	-0.8	-3.0	0.3	2.1	-0.4	-2.7	-1.8	-2.5	-3.4	1.7	-4.2	0.8	-1.8	-0.6	2.5	2.5	-1.9	-1.1	-0.1
Number of operations (self-reported)	0.4	0.6	2.9	-0.5	-1.5	-0.3	-0.4	-1.1	0.1	-0.4	0.6	-1.1	-1.0	-1.0	-1.7	-0.3	-1.2	-0.0	-0.8	-0.2	-0.4	-0.3	-0.3	0.2	-0.5
Average weekly beer plus cider intake	0.5	0.8	4.5	-0.0	-1.1	0.6	-1.3	0.4	-0.1	-1.3	-0.7	0.3	-0.3	-0.0	0.1	-2.1	0.8	-0.4	1.5	-0.1	-1.4	-1.3	0.5	0.1	-0.5
Irritability	0.3	0.5	3.2	0.6	0.6	1.4	0.1	0.7	-1.1	-0.9	-1.1	1.8	-0.1	0.6	0.3	-0.2	0.3	-0.2	0.0	0.3	-0.9	-0.8	0.3	0.3	-0.2
Risk taking	0.9	1.4	5.1	1.2	0.5	-1.2	-1.9	-0.9	2.3	0.2	-0.8	-1.5	-0.7	-1.3	-0.7	-1.4	-1.0	-0.9	0.8	-1.4	0.3	0.3	-1.2	-1.4	-1.4
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.4	-0.3	-0.6	1.4	1.6	0.4	0.8	-0.9	1.4	1.2	-0.5	0.1	0.1	0.9	0.6	-0.7	-0.0	-0.3	-1.1	-0.8	0.4	0.7	-1.1
Fractured/broken bones in last 5 years	1.0	1.3	3.4	-1.2	0.3	-0.6	-1.4	-1.5	0.5	1.8	1.4	0.1	-0.7	-1.2	-0.6	-0.5	-1.6	-0.4	-1.8	-0.8	1.7	1.8	-0.9	-0.4	-0.1
Age started oral contraceptive pill	0.3	0.4	2.1	-0.2	0.9	-0.5	0.6	0.6	0.2	-0.1	1.4	-0.1	1.5	1.0	0.4	0.1	0.1	-0.3	-0.2	0.5	-0.3	-0.2	0.3	-0.4	-0.9
Diastolic blood pressure, automated reading	0.5	1.4	5.1	-0.5	1.2	-1.2	-0.9	-1.4	-0.1	1.2	-0.1	-1.5	-0.2	-1.1	-0.8	-0.3	-1.9	-1.2	-1.0	-2.0	1.0	1.1	-2.3	-1.2	-1.0
Ever depressed for a whole week	0.4	0.5	1.7	-0.4	0.0	0.3	0.2	-0.7	1.1	1.3	-0.1	0.7	-0.6	-0.8	-0.0	0.6	-0.1	0.8	-0.6	-0.5	1.3	1.2	0.1	0.8	0.8
Unable to work because of sickness or disability	0.2	0.3	1.3	0.3	0.3	-0.6	-0.7	0.5	-0.2	-0.7	0.2	-0.2	0.7	0.6	-0.1	-1.1	0.2	-0.3	0.4	-0.2	-0.5	-0.5	0.1	-0.1	-1.1
Commuting to job workplace: Cycle	1.4	1.6	5.0	0.1	-0.4	1.2	-0.3	-1.6	-0.8	-0.9	-0.2	0.0	-2.2	-1.9	-2.2	-0.6	-1.7	-0.9	-2.0	-1.8	-0.8	-0.8	-1.1	1.1	-1.3
Myopia	0.5	0.7	2.5	-0.6	-0.7	-0.3	-0.6	-0.6	1.3	-1.0	1.6	0.3	-0.8	-0.9	-1.2	-0.8	-0.5	-0.9	0.1	-0.7	-1.0	-1.1	-0.2	0.3	-1.4
Vascular/heart problems diagnosed by doctor	0.5	1.5	6.1	-1.5	-1.0	-0.6	-1.4	-1.2	2.5	-0.3	2.1	0.3	-1.7	-2.0	-0.4	-0.8	-0.5	-1.2	-1.1	-1.0	-0.5	-0.5	-1.0	0.3	-1.3
Cholesterol lowering medication	1.0	1.4	4.0	1.4	0.3	-1.2	0.0	1.3	-1.0	1.1	-1.7	-1.0	2.0	1.6	0.5	0.0	0.3	1.5	1.5	1.4	1.4	1.3	0.7	-1.0	1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	3.0	-1.4	1.4	0.2	0.8	-0.9	-0.4	0.4	0.0	-0.6	-1.3	-0.9	-1.7	0.7	-0.9	1.3	0.1	-0.3	0.7	0.6	0.6	1.0	0.5
Pain experienced in last month	0.5	0.8	5.2	-0.7	-0.5	-1.6	-1.2	0.6	0.9	0.0	0.8	0.6	1.0	0.4	1.5	-2.3	0.5	-0.5	0.8	-0.1	-0.1	-0.2	0.1	-0.6	-1.1
Supplements: Calcium	0.5	0.6	1.9	-0.7	0.2	0.6	0.2	-0.3	-0.2	-1.0	0.7	1.3	-0.3	-0.2	0.8	0.0	0.5	-0.2	-1.3	-0.5	-1.1	-1.4	0.0	1.3	-0.8
Basal cell carcinoma (self-reported)	0.4	0.5	2.4	-0.1	-1.3	-1.5	-0.9	0.3	0.3	0.2	0.4	-0.7	0.5	0.4	0.6	-0.7	0.2	-0.7	0.9	0.6	0.2	0.3	0.1	-1.2	0.1
Heart attack/myocardial infarction (self-reported)	0.7	1.0	3.5	-0.1	1.0	-1.0	0.3	0.2	-0.3	1.2	-0.3	-1.9	1.0	0.7	-1.1	1.1	-1.1	1.2	0.6	1.2	1.5	1.6	0.5	-0.7	0.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.8	-0.2	0.4	-0.5	0.1	-1.1	0.0	0.7	-0.4	-0.6	-0.3	-1.1	-0.0	0.2	-0.6	0.5	0.3	-1.4	0.6	0.6	-0.5	-0.1	0.3
Heart disease (siblings)	0.2	0.2	0.9	0.1	-0.8	0.1	-0.1	-0.3	-1.0	0.2	0.4	0.1	0.8	0.2	-0.6	0.2	-0.7	0.3	0.1	0.6	0.2	0.2	0.1	0.1	-0.1
Alcohol drinker status: Previous	0.5	0.6	3.4	0.0	-1.1	-0.5	0.3	-0.7	-0.2	-0.1	-1.3	-1.9	-0.1	-0.5	-1.4	0.6	-1.1	0.3	0.4	-0.7	0.1	0.2	-0.8	-0.6	0.1
Pack years of smoking	1.7	2.5	6.8	1.5	0.1	1.5	2.6	1.4	-1.4	1.1	-0.9	0.9	1.6	1.8	2.2	1.8	1.7	1.9	0.9	1.7	1.2	1.1	2.1	1.0	2.3
Impedance of whole body	0.4	1.8	8.1	0.1	-0.7	1.8	1.8	1.7	-0.0	-0.8	-0.0	1.5	1.4	1.4	1.8	-0.1	2.8	0.6	1.1	0.8	-1.0	-0.9	2.2	1.3	1.2
Leg fat mass (left)	0.5	1.9	4.8	-0.2	2.2	-0.8	0.2	-0.2	-1.9	1.5	-2.2	-2.1	0.6	0.5	-1.4	1.7	-2.0	0.9	0.0	0.5	1.8	2.1	-0.3	-1.7	1.2
Arm predicted mass (left)	0.9	4.6	20.5	-0.5	1.7	-1.2	-1.1	-3.1	0.3	2.1	-0.3	-2.9	-2.0	-2.6	-3.9	1.6	-4.5	0.7	-2.1	-0.7	2.5	2.5	-2.0	-1.1	-0.3