Best TWAS P=4.56e-10 · Best GWAS P=3.28e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PPP3R1 | 0.25 | 0.22 | lasso | 4 | 0.26 | 5.4e-20 | -6.3 | -6.2 | 5.2e-10 | 0.95 | 0 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-474G23.2 | 0.17 | 0.14 | lasso | 3 | 0.12 | 2.3e-09 | -6.3 | -6.2 | 4.6e-10 | 0.97 | 0 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | WDR92 | 0.04 | 0.01 | blup | 49 | 0.01 | 7.9e-03 | -6.3 | -6.1 | 9.9e-10 | 0.49 | 0 | 0.94 | FALSE |