Best TWAS P=2.81e-11 · Best GWAS P=1.52e-09 conditioned to 0.00453
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | INADL | 0.15 | 0.06 | lasso | 5 | 0.05 | 0.00017 | 5.2 | -5.3 | 1.0e-07 | 0.81 | 0.06 | 0.48 | FALSE |
2 | GTEx | Esophagus Muscularis | TM2D1 | 0.12 | 0.03 | lasso | 3 | 0.04 | 0.00319 | 5.2 | 6.7 | 2.8e-11 | -0.55 | 0.02 | 0.87 | TRUE |