Best TWAS P=1.65e-14 · Best GWAS P=8.29e-17 conditioned to 0.000195
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 0.00003 | 8.2 | -7.7 | 1.6e-14 | -0.86 | 0.02 | 0.93 | TRUE |
2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 0.00126 | 6.2 | -6.3 | 2.4e-10 | 0.03 | 0.89 | 0.01 | TRUE |