Best TWAS P=5.08e-10 · Best GWAS P=1.5e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KDELR2 | 0.07 | 0.05 | lasso | 2 | 0.05 | 1.4e-06 | -4.6 | 5.2 | 2.7e-07 | 0.42 | 0.81 | 0.10 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | DAGLB | 0.09 | 0.06 | lasso | 5 | 0.06 | 4.8e-08 | 6.3 | -6.2 | 5.1e-10 | -0.98 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RAC1 | 0.03 | 0.02 | enet | 7 | 0.02 | 6.8e-05 | 4.2 | 5.5 | 3.7e-08 | 0.62 | 0.16 | 0.70 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DAGLB | 0.06 | 0.02 | blup | 71 | 0.03 | 7.4e-04 | 4.6 | -5.8 | 7.4e-09 | -0.72 | 0.01 | 0.75 | FALSE |