[Hub]/) : Traits : Basal metabolic rate :

chr7:74,016,979-75,842,792

Best TWAS P=1.86e-09 · Best GWAS P=1.21e-08 conditioned to 0.316

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex POM121C 0.08 0.05 lasso 2 0.04 1.1e-05 -5.7 -5.5 3.8e-08 0.99 0 1.00 FALSE
2 CommonMind Brain Pre-frontal Cortex STAG3L1 0.23 0.14 enet 13 0.17 1.0e-19 -5.7 -5.9 2.8e-09 0.91 0 1.00 FALSE
3 GTEx Adipose Subcutaneous STAG3L1 0.30 0.24 enet 24 0.27 2.4e-22 -5.7 -5.6 2.7e-08 0.92 0 1.00 FALSE
4 GTEx Adipose Visceral Omentum STAG3L1 0.20 0.19 lasso 3 0.17 2.3e-09 -5.7 -5.7 1.5e-08 1.00 0 1.00 FALSE
5 GTEx Artery Aorta STAG3L1 0.18 0.03 lasso 4 0.08 3.9e-05 -5.7 -5.5 4.3e-08 1.00 0 1.00 FALSE
6 GTEx Artery Coronary STAG3L1 0.28 0.13 lasso 4 0.17 1.8e-06 -5.3 -5.5 4.2e-08 0.86 0 0.99 FALSE
7 GTEx Artery Tibial POM121C 0.12 0.10 lasso 1 0.10 6.8e-08 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
8 GTEx Artery Tibial STAG3L1 0.25 0.19 lasso 4 0.19 8.3e-15 -5.7 -5.7 9.7e-09 1.00 0 1.00 FALSE
9 GTEx Brain Cerebellar Hemisphere POM121C 0.33 0.32 lasso 3 0.30 1.4e-08 -5.7 -5.6 2.1e-08 1.00 0 1.00 FALSE
10 GTEx Brain Cerebellum POM121C 0.30 0.15 lasso 8 0.08 2.4e-03 -5.7 -5.3 9.3e-08 0.90 0 0.97 FALSE
11 GTEx Breast Mammary Tissue STAG3L1 0.16 0.15 lasso 2 0.14 8.7e-08 -5.7 -5.7 1.1e-08 0.98 0 1.00 FALSE
12 GTEx Breast Mammary Tissue (Female) STAG3L1 0.04 0.12 lasso 1 0.04 2.9e-02 -5.7 -5.7 1.2e-08 1.00 0 0.96 FALSE
13 GTEx Cells EBV-transformed lymphocytes STAG3L1 0.43 0.21 enet 21 0.23 3.8e-08 -5.7 -6.0 1.9e-09 0.86 0 1.00 TRUE
14 GTEx Cells Transformed fibroblasts POM121C 0.15 0.06 lasso 5 0.07 1.2e-05 -5.7 -5.8 5.2e-09 0.99 0 1.00 FALSE
15 GTEx Cells Transformed fibroblasts STAG3L1 0.22 0.17 lasso 4 0.18 2.6e-13 -5.7 -5.8 7.8e-09 0.96 0 1.00 FALSE
16 GTEx Colon Sigmoid STAG3L1 0.30 0.18 lasso 4 0.18 8.5e-07 -5.7 -5.5 3.2e-08 0.97 0 1.00 FALSE
17 GTEx Colon Transverse STAG3L1 0.22 0.18 lasso 1 0.16 4.0e-08 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
18 GTEx Esophagus Gastroesophageal Junction STAG3L1 0.36 0.16 lasso 5 0.16 1.7e-06 -5.7 -5.3 1.1e-07 0.93 0 1.00 FALSE
19 GTEx Esophagus Mucosa PMS2P3 0.14 0.15 lasso 2 0.14 9.7e-10 -5.7 -5.8 6.9e-09 1.00 0 1.00 FALSE
20 GTEx Esophagus Mucosa POM121C 0.13 0.10 lasso 1 0.07 1.0e-05 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
21 GTEx Esophagus Mucosa STAG3L1 0.19 0.19 lasso 1 0.18 2.4e-12 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
22 GTEx Esophagus Muscularis STAG3L1 0.30 0.15 lasso 4 0.16 4.3e-10 -5.7 -5.3 8.8e-08 0.94 0 1.00 FALSE
23 GTEx Heart Atrial Appendage STAG3L1 0.14 0.04 enet 12 0.04 5.0e-03 -4.7 -5.2 1.9e-07 0.76 0 0.95 FALSE
24 GTEx Heart Left Ventricle POM121C 0.13 0.12 lasso 1 0.09 2.2e-05 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
25 GTEx Lung POM121C 0.13 0.10 lasso 3 0.10 7.8e-08 -5.7 -5.7 1.6e-08 0.98 0 1.00 FALSE
26 GTEx Muscle Skeletal PMS2P3 0.07 0.07 lasso 2 0.06 3.8e-06 -5.7 -5.6 1.7e-08 1.00 0 1.00 FALSE
27 GTEx Muscle Skeletal TRIM73 0.08 0.05 enet 11 0.06 3.4e-06 -5.7 -5.5 4.0e-08 0.88 0 1.00 FALSE
28 GTEx Nerve Tibial POM121C 0.22 0.14 lasso 5 0.14 6.9e-10 -5.7 -5.8 9.0e-09 0.97 0 1.00 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic PMS2P3 0.26 0.19 lasso 3 0.17 1.3e-09 -5.7 -5.4 5.3e-08 0.99 0 1.00 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic STAG3L1 0.13 0.19 lasso 1 0.18 2.6e-10 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
31 GTEx Skin Sun Exposed Lower leg PMS2P3 0.38 0.30 lasso 3 0.29 1.9e-24 -5.7 -5.8 8.6e-09 1.00 0 1.00 FALSE
32 GTEx Skin Sun Exposed Lower leg STAG3L1 0.27 0.15 lasso 5 0.15 1.3e-12 -5.7 -5.9 4.8e-09 0.98 0 1.00 FALSE
33 GTEx Stomach PMS2P3 0.16 0.07 lasso 5 0.09 3.7e-05 -5.3 -5.2 1.8e-07 0.91 0 0.99 FALSE
34 GTEx Stomach TRIM73 0.23 0.09 lasso 5 0.09 3.2e-05 -5.7 -5.4 7.3e-08 0.96 0 0.99 FALSE
35 GTEx Stomach STAG3L1 0.35 0.20 lasso 5 0.18 4.2e-09 -5.3 -5.3 1.1e-07 0.86 0 1.00 FALSE
36 GTEx Testis TRIM73 0.20 0.21 lasso 2 0.19 6.2e-09 -5.7 -5.7 1.3e-08 1.00 0 1.00 FALSE
37 GTEx Testis STAG3L1 0.24 0.24 enet 14 0.27 1.4e-12 -5.7 -5.7 1.3e-08 0.88 0 1.00 FALSE
38 GTEx Thyroid POM121C 0.14 0.08 lasso 3 0.07 3.4e-06 -5.7 -5.8 8.7e-09 0.96 0 1.00 FALSE
39 GTEx Thyroid STAG3L1 0.36 0.24 enet 17 0.27 8.0e-21 -5.7 -5.3 1.1e-07 0.92 0 1.00 FALSE
40 GTEx Whole Blood STAG3L1 0.08 0.06 lasso 3 0.07 2.8e-07 -5.7 -5.6 1.8e-08 1.00 0 1.00 FALSE
41 METSIM Adipose POM121C 0.11 0.08 lasso 1 0.08 1.6e-11 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
42 ROSMAP Brain Pre-frontal Cortex PMS2P3 0.05 0.04 lasso 1 0.03 4.6e-05 -5.7 -5.7 1.2e-08 1.00 0 1.00 FALSE
43 ROSMAP Brain Pre-frontal Cortex POM121C 0.36 0.26 lasso 7 0.27 2.8e-34 -5.7 -5.8 7.8e-09 0.99 0 1.00 FALSE
44 ROSMAP Brain Pre-frontal Cortex STAG3L1 0.46 0.32 lasso 4 0.32 2.2e-42 -5.7 -5.7 1.0e-08 1.00 0 1.00 FALSE
45 ROSMAP Brain Pre-frontal Cortex GTF2IP1 0.09 0.06 lasso 3 0.05 1.7e-07 -5.7 -5.7 1.1e-08 1.00 0 1.00 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma POM121C 0.04 0.04 lasso 2 0.03 1.2e-07 -5.7 -5.6 1.7e-08 1.00 0 1.00 FALSE
47 The Cancer Genome Atlas Thyroid Carcinoma POM121C 0.08 0.07 lasso 3 0.07 3.6e-07 -5.7 -5.8 7.2e-09 0.99 0 1.00 FALSE
48 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma PMS2L3 0.23 0.14 lasso 2 0.14 1.3e-04 -5.7 -5.7 1.6e-08 0.98 0 0.91 FALSE