[Hub]/) : Traits : Basal metabolic rate : ← →

chr7:74,016,979-75,842,792

Best TWAS P=1.86e-09 · Best GWAS P=1.21e-08 conditioned to 0.316

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP4	joint
13	GTEx	Cells EBV-transformed lymphocytes	STAG3L1	0.43	0.21	enet	21	0.23	3.8e-08	-5.7	-6.0	1.9e-09	0.86	1.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	STAG3L1	0.23	0.14	enet	13	0.17	1.0e-19	-5.7	-5.9	2.8e-09	0.91	1.00	FALSE
32	GTEx	Skin Sun Exposed Lower leg	STAG3L1	0.27	0.15	lasso	5	0.15	1.3e-12	-5.7	-5.9	4.8e-09	0.98	1.00	FALSE
14	GTEx	Cells Transformed fibroblasts	POM121C	0.15	0.06	lasso	5	0.07	1.2e-05	-5.7	-5.8	5.2e-09	0.99	1.00	FALSE
19	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	-5.7	-5.8	6.9e-09	1.00	1.00	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	POM121C	0.08	0.07	lasso	3	0.07	3.6e-07	-5.7	-5.8	7.2e-09	0.99	1.00	FALSE
15	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	-5.7	-5.8	7.8e-09	0.96	1.00	FALSE
43	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	-5.7	-5.8	7.8e-09	0.99	1.00	FALSE
31	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	-5.7	-5.8	8.6e-09	1.00	1.00	FALSE
38	GTEx	Thyroid	POM121C	0.14	0.08	lasso	3	0.07	3.4e-06	-5.7	-5.8	8.7e-09	0.96	1.00	FALSE
28	GTEx	Nerve Tibial	POM121C	0.22	0.14	lasso	5	0.14	6.9e-10	-5.7	-5.8	9.0e-09	0.97	1.00	FALSE
8	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	-5.7	-5.7	9.7e-09	1.00	1.00	FALSE
44	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	-5.7	-5.7	1.0e-08	1.00	1.00	FALSE
11	GTEx	Breast Mammary Tissue	STAG3L1	0.16	0.15	lasso	2	0.14	8.7e-08	-5.7	-5.7	1.1e-08	0.98	1.00	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	-5.7	-5.7	1.1e-08	1.00	1.00	FALSE
7	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
12	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	-5.7	-5.7	1.2e-08	1.00	0.96	FALSE
17	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
20	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
21	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
24	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
41	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	-5.7	-5.7	1.2e-08	1.00	1.00	FALSE
36	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	-5.7	-5.7	1.3e-08	1.00	1.00	FALSE
37	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	-5.7	-5.7	1.3e-08	0.88	1.00	FALSE
4	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	-5.7	-5.7	1.5e-08	1.00	1.00	FALSE
25	GTEx	Lung	POM121C	0.13	0.10	lasso	3	0.10	7.8e-08	-5.7	-5.7	1.6e-08	0.98	1.00	FALSE
48	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	-5.7	-5.7	1.6e-08	0.98	0.91	FALSE
26	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	-5.7	-5.6	1.7e-08	1.00	1.00	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	-5.7	-5.6	1.7e-08	1.00	1.00	FALSE
40	GTEx	Whole Blood	STAG3L1	0.08	0.06	lasso	3	0.07	2.8e-07	-5.7	-5.6	1.8e-08	1.00	1.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	-5.7	-5.6	2.1e-08	1.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	-5.7	-5.6	2.7e-08	0.92	1.00	FALSE
16	GTEx	Colon Sigmoid	STAG3L1	0.30	0.18	lasso	4	0.18	8.5e-07	-5.7	-5.5	3.2e-08	0.97	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	-5.7	-5.5	3.8e-08	0.99	1.00	FALSE
27	GTEx	Muscle Skeletal	TRIM73	0.08	0.05	enet	11	0.06	3.4e-06	-5.7	-5.5	4.0e-08	0.88	1.00	FALSE
6	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	-5.3	-5.5	4.2e-08	0.86	0.99	FALSE
5	GTEx	Artery Aorta	STAG3L1	0.18	0.03	lasso	4	0.08	3.9e-05	-5.7	-5.5	4.3e-08	1.00	1.00	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	PMS2P3	0.26	0.19	lasso	3	0.17	1.3e-09	-5.7	-5.4	5.3e-08	0.99	1.00	FALSE
34	GTEx	Stomach	TRIM73	0.23	0.09	lasso	5	0.09	3.2e-05	-5.7	-5.4	7.3e-08	0.96	0.99	FALSE
22	GTEx	Esophagus Muscularis	STAG3L1	0.30	0.15	lasso	4	0.16	4.3e-10	-5.7	-5.3	8.8e-08	0.94	1.00	FALSE
10	GTEx	Brain Cerebellum	POM121C	0.30	0.15	lasso	8	0.08	2.4e-03	-5.7	-5.3	9.3e-08	0.90	0.97	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	STAG3L1	0.36	0.16	lasso	5	0.16	1.7e-06	-5.7	-5.3	1.1e-07	0.93	1.00	FALSE
35	GTEx	Stomach	STAG3L1	0.35	0.20	lasso	5	0.18	4.2e-09	-5.3	-5.3	1.1e-07	0.86	1.00	FALSE
39	GTEx	Thyroid	STAG3L1	0.36	0.24	enet	17	0.27	8.0e-21	-5.7	-5.3	1.1e-07	0.92	1.00	FALSE
33	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	-5.3	-5.2	1.8e-07	0.91	0.99	FALSE
23	GTEx	Heart Atrial Appendage	STAG3L1	0.14	0.04	enet	12	0.04	5.0e-03	-4.7	-5.2	1.9e-07	0.76	0.95	FALSE