TWAS
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Models
Genes
Traits
[Hub]/) :
Traits
:
Basal metabolic rate
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chr7:139,475,320-140,010,108
Best TWAS P=6.91e-10 · Best GWAS P=5.96e-09 conditioned to 0.815
139.5M
139.6M
139.7M
139.8M
139.9M
140M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
PARP12
0.14
0.11
enet
10
0.12
9.4e-12
5.8
-6.2
6.9e-10
-0.93
0.00
1.00
TRUE
1
The Cancer Genome Atlas
Lung Adenocarcinoma
PARP12
0.02
0.01
blup
68
0.01
2.4e-02
5.6
-5.9
2.8e-09
-0.88
0.01
0.91
FALSE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
PARP12
0.06
0.04
lasso
2
0.04
1.3e-04
5.5
5.3
1.2e-07
0.93
0.01
0.97
FALSE