Best TWAS P=1.32e-09 · Best GWAS P=6.89e-11 conditioned to 0.0205
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNHIT6 | 0.05 | 0.01 | bslmm | 552 | 0.01 | 1.9e-02 | 4.6 | -5.6 | 2.6e-08 | -0.04 | 0.16 | 0.34 | TRUE |
| 2 | GTEx | Adrenal Gland | DDAH1 | 0.26 | 0.21 | lasso | 6 | 0.20 | 8.7e-08 | 4.3 | -5.5 | 5.1e-08 | -0.05 | 0.15 | 0.84 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | C1orf52 | 0.05 | 0.02 | blup | 564 | 0.03 | 9.5e-05 | 3.0 | 5.3 | 1.0e-07 | 0.01 | 0.30 | 0.53 | FALSE |
| 4 | YFS | Blood | BCL10 | 0.24 | 0.12 | enet | 48 | 0.19 | 1.1e-59 | 4.0 | 5.3 | 1.2e-07 | -0.03 | 0.91 | 0.08 | TRUE |
| 5 | YFS | Blood | ODF2L | 0.04 | 0.04 | enet | 18 | 0.04 | 1.8e-12 | 6.4 | -6.1 | 1.3e-09 | -0.91 | 0.00 | 1.00 | TRUE |